What's New in Cardiac MRI? — May 20, 2026
AI-summarised digest of 62 PubMed articles on Cardiac MRI published in the last 7 days.
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What’s New in Cardiac MRI?
May 20, 2026 · 62 articles · 15 research themes · covering May 13, 2026 – May 20, 2026
Overview
Across this week’s PubMed set, a dominant thread is the expanding role of multimodality cardiac imaging—especially cardiac MRI (CMR)—to detect, phenotype, and risk-stratify myocardial disease that can be missed by standard tests. Several inflammatory cardiomyopathy-focused papers emphasize that CMR tissue characterization (e.g., LGE, T1/ECV mapping) and structured imaging criteria improve diagnostic precision and management planning, while serial imaging can track disease trajectory. Complementary modalities such as echocardiographic strain and PET/CT are repeatedly positioned as add-ons that improve etiology and prognostication, particularly when clinical presentations overlap (e.g., myocarditis vs sarcoidosis vs infection).
A second major theme is biomarker- and risk-model–driven prediction of cardiovascular outcomes, often linked to CMR-derived substrates. Studies connect inflammatory biomarkers (e.g., sST2) and cardiometabolic surrogates (e.g., insulin resistance via eGDR; metabolic phenotypes) to myocardial fibrosis and future heart failure risk. Prognostic CMR metrics such as left atrioventricular coupling (LACI) and feature-text-driven cine CMR models illustrate a shift toward scalable, interpretable risk stratification. In parallel, iron deficiency emerges as a mechanistic target in HFpEF and HFrEF contexts, with trials and substudies testing whether iron repletion improves myocardial energetics or dyssynchrony.
Finally, the digest highlights rapid growth in computational cardiology: annotation-free ROI localization, faster registration, foundation models for cine CMR analysis, and AI frameworks for early detection of inflammatory/infiltrative cardiomyopathies. These advances aim to reduce bottlenecks in imaging interpretation and enable broader, earlier detection in real-world settings (including mobile CMR and EHR-linked outcomes). Case reports and clinical studies also underscore the breadth of “cardiac mimics” and rare etiologies—ranging from tuberculous myocarditis and epicardial fat necrosis to cardiac metastases, carcinoid-related venous obstruction, and drug/supplement cardiotoxicity—where multimodality imaging and careful longitudinal assessment are crucial.
Inflammatory cardiomyopathies & myocarditis (imaging/diagnosis/risk)
Multimodality Imaging in Inflammatory Cardiac Disease.
This review studied multimodality imaging strategies for inflammatory cardiac diseases—including myocarditis, cardiac sarcoidosis, infective endocarditis, and pericarditis—in clinical practice. It found that echocardiography (transthoracic and transesophageal) is first-line for conditions such as infective endocarditis and pericardial effusion, while cardiac MRI provides gold-standard tissue characterization for myocarditis and cardiac sarcoidosis and CT and FDG-PET/CT add complementary anatomic and inflammatory information. The clinical significance is improved diagnostic precision and management planning by matching the imaging modality to the specific inflammatory cardiac pathology.
Mahmood A, Ramesh J, Patel DS et al. · Cardiology in review · (2026) · View on PubMed ↗
Insights Into the Natural History of Recurrent Myocarditis, A Multicenter International Study (Re-Myo Study).
This multicenter international Re-Myo study characterized the natural history and outcomes of recurrent acute myocarditis (Re-AM) in 141 patients with biopsy- or cardiac MRI–proven recurrence (median age 35 years, 77% male) compared with 372 patients with a single acute myocarditis episode. Re-AM patients had distinct clinical characteristics and outcomes, with the study’s primary endpoint combining all-cause mortality, heart transplant, and major ventricular arrhythmias. The findings are significant for risk stratification and management planning after myocarditis recurrence, where evidence has previously been limited.
Baggio C, Cannata A, Gasperetti A et al. · Journal of the American Heart Association · (2026) · View on PubMed ↗ · Free PDF ↗
Inflammatory cardiomyopathy: Position paper of the Italian Society of Cardiology Working Group on cardiomyopathies and pericardial diseases in collaboration with the Italian Society of Cardiology Working Group on cardiac magnetic resonance.
This position paper from Italian Society of Cardiology working groups in collaboration with the Italian Society of Cardiology Working Group on cardiac magnetic resonance defined inflammatory cardiomyopathy (iCMP) as the chronic hypokinetic phenotype within the myocarditis spectrum characterized by persistent inflammation, systolic dysfunction, and adverse remodeling. It emphasizes that iCMP often follows prior acute/subacute myocarditis, has heterogeneous causes (infectious, autoimmune, idiopathic) with possible genetic susceptibility in a two-hit model, and requires a multimodal diagnostic approach. The document provides a clinical framework to standardize recognition, diagnosis, and risk assessment of iCMP to reduce progression to dilated cardiomyopathy, heart failure, and arrhythmias.
Imazio M, Jahnsen V, Merlo M et al. · International journal of cardiology · (2026) · View on PubMed ↗ · Free PDF ↗
Multimodality Imaging in Myocarditis: Integrating Etiology, Diagnosis, and Risk Stratification.
This review synthesized evidence on multimodality cardiac imaging in myocarditis, focusing on how cardiac magnetic resonance (including parametric mapping and updated Lake Louise Criteria), echocardiographic strain, and positron emission techniques contribute to etiology, diagnosis, and risk stratification. It concludes that CMR is the reference noninvasive modality and that combining CMR with strain imaging and PET can enhance detection of subclinical dysfunction and improve longitudinal management. The clinical significance is a practical imaging integration pathway to better phenotype myocarditis and guide follow-up and risk management.
Debs D, Rushworth P, Liu J et al. · Current cardiology reports · (2026) · View on PubMed ↗
Cardiac sarcoidosis & granulomatous/infectious mimics
Ventricular Tachycardia as the Initial Presentation of Tuberculous Myocarditis.
This case studied a 47-year-old man from a tuberculosis-endemic region presenting with sustained monomorphic ventricular tachycardia and elevated cardiac biomarkers, with normal coronary angiography. Multimodal imaging showed extensive inflammatory nonischemic myocardial involvement and mediastinal lymphadenopathy, and initial lymph node biopsy with nonnecrotizing granulomas led to probable cardiac sarcoidosis and corticosteroid treatment before delayed culture confirmed Mycobacterium tuberculosis. The clinical significance is that tuberculous myocarditis can closely mimic cardiac sarcoidosis in ventricular arrhythmia presentations, so definitive microbiologic testing is crucial to guide appropriate therapy.
Subira-Ingla A, Francisco-Pascual J, Santos-Ortega A et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Immune checkpoint inhibitor (ICI) cardiotoxicity/myocarditis
Diagnostic and prognostic parameters for immune checkpoint inhibitor-related myocarditis: A meta-analysis.
This meta-analysis evaluated diagnostic and prognostic parameters for immune checkpoint inhibitor-related myocarditis (ICI-M) across 29 trials including 3568 patients. Abnormal cardiac magnetic resonance imaging (CMR) was present in 63.4%, with late gadolinium enhancement (LGE) in 65.3%, and the pooled odds ratio for LGE was reported as 5.32 (95% CI 1.61–17.50). These results support CMR—particularly LGE—as a key diagnostic indicator and help clarify which measurable parameters may carry prognostic value in ICI-M.
Lerchner T, Buehning F, Vogel J et al. · European journal of cancer (Oxford, England : 1990) · (2026) · View on PubMed ↗ · Free PDF ↗
Prospective Serial Cardiovascular Magnetic Resonance Imaging of Immune Checkpoint Inhibitor Myocarditis Correlates with Cardiovascular Outcomes.
This prospective study evaluated serial cardiovascular magnetic resonance (CMR) imaging as a predictor of outcomes in patients with immune checkpoint inhibitor (ICI) myocarditis versus pre-ICI controls scheduled to receive ICI therapy. The key finding was that changes in CMR parameters over follow-up at 8–12 weeks correlated with adverse cardiovascular outcomes (ACE) in the ICI myocarditis cohort. The scientific significance is that prospective serial CMR may offer a noninvasive way to monitor ICI myocarditis trajectory and stratify prognosis beyond biomarkers alone.
Kwan JM, Khattab M, Tysarowski M et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac biomarkers for cardiac inflammation/remodeling
Elevated sST2 associates with cardiac involvement and declines after treatment in newly diagnosed patients with idiopathic inflammatory myopathies.
This cohort study measured soluble suppression of tumorigenicity 2 (sST2) longitudinally in newly diagnosed and established patients with idiopathic inflammatory myopathies (IIM), compared with age- and gender-matched healthy controls and patients with rheumatoid arthritis. It found that elevated sST2 was associated with cardiac involvement and declined after treatment over time in newly diagnosed IIM patients. The significance is that sST2 may serve as a clinically useful biomarker for cardiac inflammation/remodeling and for monitoring treatment response in IIM.
Hanna B, Lundberg IE, Ekwall AH et al. · Arthritis research & therapy · (2026) · View on PubMed ↗
High-Sensitivity Cardiac Troponin in Hypertrophic Cardiomyopathy: Diagnostic Insights and Future Directions.
This narrative review synthesized observational cohort, mechanistic, and longitudinal evidence on high-sensitivity cardiac troponin (hs-cTn) in hypertrophic cardiomyopathy (HCM) to clarify diagnostic patterns and prognostic associations across phenotypic heterogeneity. Across multiple cohorts, hs-cTn elevation was reported in roughly one-quarter to one-half of patients and was linked to myocardial stress and outcomes in nonischemic cardiomyopathy contexts. The review supports hs-cTn as a potentially useful biomarker for risk stratification and future clinical decision-making in HCM, while highlighting the need for standardized interpretation.
Hassan A, Mizori R, Malik A et al. · Cardiology in review · (2026) · View on PubMed ↗ · Free PDF ↗
Heart failure risk prediction & prognostic CMR biomarkers
Glucose Disposal Rate: A Novel Measure of Insulin Resistance Associated With Myocardial Fibrosis and Incident Heart Failure.
This study evaluated whether the estimated glucose disposal rate (eGDR), a surrogate of insulin resistance, is associated with myocardial fibrosis and incident heart failure in 6,025 MESA participants free of heart failure at exam 2 (2002–2004). Lower eGDR (higher insulin resistance) was linked to greater myocardial fibrosis on cardiac magnetic resonance imaging (2010–2012) and to higher risk of developing heart failure during follow-up. Scientifically, it connects cardiometabolic insulin resistance to myocardial remodeling and provides a measurable risk marker that could refine prevention strategies for heart failure.
Bukhari S, Kwapong YA, Yanek LR et al. · Journal of the American Heart Association · (2026) · View on PubMed ↗ · Free PDF ↗
Associations of Metabolic Phenotypes with Cardiac Structure and Clinical Outcomes: Insights from the UK Biobank.
Using the UK Biobank cohort of 22,789 participants followed a median 5.1 years, this study examined how metabolic phenotypes (metabolically healthy nonobese vs obese; metabolically unhealthy nonobese vs obese) relate to cardiac magnetic resonance (CMR) measures and clinical outcomes. Metabolically unhealthy and/or obese phenotypes showed worse cardiac structure and were associated with poorer clinical outcomes over follow-up. This is clinically important because it suggests that combining obesity status with metabolic health improves prediction of subclinical cardiac damage and future risk.
Bogner B, Jung M, Reisert M et al. · The Journal of clinical endocrinology and metabolism · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗
A composable multimodal framework for cine CMR-text-driven prediction of heart failure outcomes.
This study proposed and evaluated a composable multimodal framework for predicting heart failure outcomes using cine CMR text-driven features. The key idea is that combining multimodal inputs (including text-derived information from cine CMR) can improve prediction of heart failure outcomes compared with more limited approaches. Scientifically, it advances interpretable, scalable risk modeling that could support more holistic patient assessment and treatment optimization in heart failure.
Chen J, Sun J, Wang X et al. · Physiological measurement · (2026) · View on PubMed ↗ · Free PDF ↗
Design and Rationale of the WE-CARE-HF-CMR Trial: Cardiorenal Care on Wheels for Asymptomatic Heart Failure Patients (NCT07185100).
The WE-CARE-HF-CMR trial is designed to evaluate cardiorenal care on wheels for asymptomatic heart failure patients using mobile cardiac MRI, focusing on detecting subclinical myocardial dysfunction. The rationale is that left ventricular global longitudinal strain (GLS) is more sensitive than left ventricular ejection fraction (LVEF), building on prior HERZCHECK data showing GLS-defined pre–heart failure (stage B HF) in rural Germany. If successful, the trial could establish a scalable approach to identify asymptomatic HF earlier in real-world (including urban) settings using mobile CMR.
Li JJ, Thiede G, Götze C et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac magnetic resonance-derived left atrioventricular coupling index predicts outcome in reduced ejection fraction.
Using the multicenter DERIVATE registry, investigators calculated a cardiac magnetic resonance–derived left atrioventricular coupling index (LACI = left atrial end-diastolic volume / left ventricular end-diastolic volume) in patients with heart failure and reduced ejection fraction (LVEF <50%) to predict outcomes. Higher or altered LACI was associated with increased risk of all-cause mortality and heart failure outcomes in Cox regression models. This supports LACI as a CMR-based prognostic biomarker that could improve risk stratification in reduced-EF heart failure.
Guglielmo M, Fedele D, Bergamaschi L et al. · ESC heart failure · (2026) · View on PubMed ↗ · Free PDF ↗
Characterisation of Incident Heart Failure after Ischaemic Stroke/Transient Ischaemic Attack: A UK Biobank Study.
In a prospective UK Biobank cohort of 405,406 participants aged 40–69 years without prior heart failure, investigators assessed incident heart failure after ischemic stroke/TIA and characterized associated cardiac MRI findings. Incident HF risk was quantified in stroke/TIA survivors, and CMR findings were used to describe the cardiac substrate linked to subsequent HF and mortality. This is clinically significant because it clarifies post-stroke/TIA HF risk and identifies CMR features that may help stratify patients for closer monitoring.
Muthalaly RG, Nerlekar N, Tan S et al. · ESC heart failure · (2026) · View on PubMed ↗ · Free PDF ↗
Iron deficiency and iron-related heart failure mechanisms
Intravenous IRON supplementation in Heart Failure with Preserved Ejection Fraction and iron deficiency (IRON-HFpEF): a comprehensive phase II multicentre placebo-controlled randomised clinical trial.
In the phase II multicentre randomized placebo-controlled IRON-HFpEF trial, 45 patients with heart failure with preserved ejection fraction (LV ejection fraction ≥50%) and iron deficiency (excluding those with iron-deficiency anemia) were randomized to intravenous ferric carboxymaltose (FCM) versus placebo. The trial assessed mechanistic effects on cardiovascular function and exercise tolerance using exercise right-heart catheterization, 6-minute walking distance (6MWD), cardiac MRI, and 31P-magnetic resonance spectroscopy of calf muscle at baseline and 4 months. If FCM improves these exercise and myocardial energetic endpoints, it would provide mechanistic and clinical rationale for treating iron deficiency in HFpEF beyond anemia status.
van de Bovenkamp AA, Nassiri S, de Man FS et al. · European journal of heart failure · (2026) · View on PubMed ↗ · Free PDF ↗
Role of dyssynchrony in short-term left ventricular systolic function after iron repletion in patients with heart failure.
This subanalysis of the Myocardial-IRON trial studied whether intravenous iron repletion with ferric carboxymaltose (FCM) affects short-term mechanical dyssynchrony in patients with heart failure (LVEF <50%) and iron deficiency, using cardiac magnetic resonance feature tracking to derive the longitudinal systolic dyssynchrony index (L-SDI). FCM was evaluated for its short-term impact on L-SDI and for associations between changes in dyssynchrony and response to cardiac resynchronization therapy (CRT). The findings are scientifically significant because they test a mechanistic link between iron repletion and improved ventricular synchrony that could help explain clinical benefits of intravenous iron in HF.
Del Canto I, Miñana G, Cardells I et al. · Communications medicine · (2026) · View on PubMed ↗ · Free PDF ↗
Aortic valve disease (aortic regurgitation/stenosis) & surgical outcomes
Contemporary Overview of Aortic Regurgitation in Young Individuals: Insights From Real-Life Evidence.
This article reviews contemporary evidence on aortic regurgitation (AR) in young adults aged 18–44 years, focusing on diagnostic strategies and timing of intervention. It emphasizes that prognosis depends on AR severity, underlying etiology, early left-ventricular dysfunction, and intervention choice, and that newer echocardiography-based thresholds for left-ventricular structural/functional assessment may better guide surgery timing in asymptomatic chronic AR. Clinically, it supports prompt multimodality evaluation (with echocardiography as the core test) to reduce under- or misdiagnosis and improve outcomes in younger patients.
Sozzi FB, Gamberini G, Kim JK et al. · Journal of the American Heart Association · (2026) · View on PubMed ↗ · Free PDF ↗
Interstitial Myocardial Fibrosis Analysis by Histology and Cardiac Magnetic Resonance in Severe Aortic Valve Disease.
In 108 patients undergoing aortic valve replacement with myocardial biopsy, this study compared interstitial myocardial fibrosis measured by collagen volume fraction (CVF) against cardiac MRI markers of fibrosis in severe aortic valve disease. Preoperative CMR included late gadolinium enhancement (LGE) and extracellular volume (ECV) derived from native and post-contrast T1 mapping, and these imaging measures were correlated with biopsy CVF. The significance is that ECV (interstitial fibrosis proxy) may better reflect diffuse myocardial fibrosis than LGE alone, potentially improving risk stratification and treatment targeting in severe aortic stenosis.
Bello JHSM, Demarchi LMMF, Fonseca RA et al. · Arquivos brasileiros de cardiologia · (2026) · View on PubMed ↗
Left Ventricular Rehabilitation after Ross operation for Critical Aortic Stenosis with Endocardial Fibroelastosis.
This study assessed long-term clinical and functional outcomes after Ross operation in patients with critical aortic stenosis, comparing those with and without endocardial fibroelastosis (EFE) and focusing on left ventricular (LV) performance. Patients underwent Ross surgery before age 1 year (neonatal/infant) between 2005 and 2025, and outcomes were analyzed using demographic, echocardiographic, and long-term clinical data. The significance is that it clarifies whether early Ross (with or without EFE resection) preserves or restores LV function over time, informing surgical and rehabilitation planning for this high-risk congenital subgroup.
Jacob KA, Korsuize NA, van Wijk A et al. · The Journal of thoracic and cardiovascular surgery · (2026) · View on PubMed ↗ · Free PDF ↗
Congenital/early-life cardiovascular programming (preterm birth, pediatric syndromes)
Structural and Functional Abnormalities in the Preterm Heart: From Development to Adulthood.
This review studied how preterm birth affects cardiac structure and function from development through adulthood, focusing on mechanisms that increase later cardiovascular disease risk. It found that multiple pathways—such as abnormal oxygen exposure, altered extracellular matrix composition, mitochondrial dysfunction in cardiomyocytes, immature sarcoplasmic/endoplasmic reticulum, and increased procedural stress—contribute to long-term cardiovascular vulnerability even when early hearts appear structurally normal. The significance is supporting the rationale for heightened clinical surveillance and guiding future research into targeted prevention strategies for adults born preterm.
Zegelbone P, Young K, Hughes F et al. · Journal of the American Heart Association · (2026) · View on PubMed ↗ · Free PDF ↗
Smaller coronary artery size in adults born preterm.
This study used 1.5T cardiac MRI in adults to test whether coronary artery size is reduced in people born preterm, measuring left main (LM), left anterior descending (LAD), and right coronary artery (RCA) dimensions with 3D bSSFP coronary MR angiography. Adults born preterm had smaller coronary artery size (reduced LM/LAD/RCA area and/or diameter) than adults born at term. These findings suggest that preterm birth may program long-term coronary vascular development, potentially contributing to higher adult ischemic heart disease risk.
Barton GP, Sharma K, Hussain T et al. · Pediatric research · (2026) · View on PubMed ↗
Coronary/ischemia evaluation & coronary anatomy–physiology frameworks
Integrating Anatomy and Ischemia in Chest Pain Evaluation.
This American Journal of Cardiology review integrated anatomic and physiologic approaches to chest pain evaluation using noninvasive and invasive coronary assessment strategies. It highlights coronary CT angiography with or without CT-derived fractional flow reserve and functional imaging (e.g., stress echocardiography, PET myocardial blood flow/coronary flow reserve, and stress CMR) for triage and characterization, and invasive coronary angiography with physiology (FFR/iFR) plus intravascular imaging (IVUS and optical coherence tomography). The synthesis supports a combined anatomy–ischemia framework to improve diagnostic accuracy and guide management in suspected coronary artery disease.
Tiotsop M, Salabei JK · The American journal of cardiology · (2026) · View on PubMed ↗
Giant Postischemic Left Ventricular Aneurysm Without Q Waves: Multimodality Imaging-Guided Surgery.
This JACC Case Reports study examined a 55-year-old woman with inferolateral myocardial infarction who developed a giant postischemic left ventricular aneurysm without diagnostic Q waves. Multimodality imaging showed progressive left ventricular remodeling with aneurysmal evolution and mural thrombus despite serial electrocardiograms lacking pathological Q waves, guiding multimodality imaging-guided surgical management. The significance is that clinicians should not rely solely on Q waves for aneurysm suspicion, as advanced imaging can reveal evolving aneurysm and thrombus even when ECG findings are misleading.
Gaido L, Attisani M, Scalini F et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Bilateral Coronary Artery-to-Pulmonary Artery Fistula Treated Using Minimally Invasive Coils and Vascular Embolization Devices.
This case studied a 44-year-old woman with bilateral coronary artery-to-pulmonary artery fistulas (CAPF) causing exertional dyspnea and stress cardiac magnetic resonance–proven myocardial ischemia. The fistulas were successfully treated with a minimally invasive endovascular strategy using pulmonary artery–side vascular occlusion devices followed by coil embolization of the coronary artery–side inflow sites. The report highlights that even when Qp/Qs is near-normal, stress CMR can detect ischemia and targeted coil/embolization can be an effective, less invasive treatment for complex bilateral CAPF.
Takagi R, Irita J, Akazawa Y et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac tumors/metastases & tumor-related cardiac disease
Imaging of Myocardial Carcinoid Metastasis.
This JACC Case Reports study described two patients with metastatic neuroendocrine tumors (NETs) presenting with isolated myocardial metastases without valvular involvement. It found that Gallium-68 DOTATATE PET/CT identified the cardiac metastases and cardiac MRI further characterized them, whereas transthoracic echocardiography had limited ability to detect myocardial involvement. The clinical significance is that multimodality imaging can improve detection and characterization of rare, often asymptomatic cardiac NET metastases.
Ranganath S, Ynalvez L, Ryoo Ali HJ et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac tumour in paediatrics: the role of multimodal imaging and therapeutic catheterisation.
This case report studied a pediatric patient with a cardiac tumor initially misdiagnosed as asymmetric septal hypertrophic cardiomyopathy, using multimodal imaging and therapeutic catheter-based management. It found that echocardiography showed a large interventricular septal mass with central vascularization and a severe right ventricular outflow tract gradient, while cardiac MRI confirmed a highly vascularized lesion with characteristic signal features and a markedly increased extracellular volume. The significance is demonstrating how multimodal imaging can correct diagnostic uncertainty in children and guide appropriate therapeutic catheterization planning.
Trujeque L, Hernandez K, Tavera A · Cardiology in the young · (2026) · View on PubMed ↗ · Free PDF ↗
Rapid Onset of Iron Overload Cardiomyopathy in Cirrhosis.
This JACC Case Reports report described two men with cirrhosis who developed iron overload cardiomyopathy (IOC) without hereditary hemochromatosis or transfusion-dependent anemia. Both patients rapidly progressed to severe cardiomyopathy with markedly reduced left ventricular ejection fraction after previously higher values, consistent with IOC emerging in the setting of cirrhosis-related iron accumulation. The significance is that clinicians should consider IOC as a potential, treatable cause of new heart failure in cirrhosis even without classic hereditary or transfusion risk factors.
Nouraee CM, Swain WH, Harmon DM et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Right Ventricular Metastasis From Rectal Cancer Recurrence.
This case report described a 55-year-old man with prior rectal adenocarcinoma recurrence concern, where multimodality imaging identified a right ventricular metastasis from rectal cancer recurrence. Cardiac MRI revealed a large right ventricular free-wall lesion with endoluminal growth and late enhancement, and intracardiac echocardiography-guided endomyocardial biopsy was used to obtain tissue diagnosis. The clinical significance is that cardiac metastasis can present as an isolated intracardiac mass, and CMR plus biopsy can enable diagnosis even when extracardiac disease is not evident.
Vilela M, Cazeiro D, Ferreira D et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Inferior Vena Cava Stenosis Mimicking Right Heart Failure in Carcinoid Heart Disease.
This case report described two patients with advanced carcinoid heart disease in whom serotonin-mediated fibrosis caused inferior vena cava (IVC) stenosis, mimicking right heart failure. The authors highlight that venous outflow obstruction from carcinoid-related fibrosis can produce a decompensation phenotype indistinguishable from valvular disease, despite the typical right-sided valve involvement. The significance is that clinicians should evaluate for venous outflow obstruction (e.g., IVC stenosis) when carcinoid patients present with right-sided failure symptoms that do not fully match expected valvular findings.
Vila-Sanjuán S, Vallejo N, Martí-Aguasca G et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac masses, rare cysts, and parasitic disease
Massive cardiac echinococcosis.
This report described a case of massive cardiac echinococcosis presenting with atypical symptoms such as chest pain or breathlessness and characterized the disease using multimodal imaging. The authors used chest radiography, CT, and cardiac MRI to document the cardiac hydatid cyst involvement. The clinical significance is heightened awareness that hydatid disease can involve the heart and may require comprehensive imaging to establish diagnosis and guide management.
Rai P, Aswani Y · The international journal of cardiovascular imaging · (2026) · View on PubMed ↗
Epicardial Fat Necrosis as a Rare Cause of Chest Pain: Peeling Back the Layers.
This case report described two patients with acute severe pleuritic chest pain ultimately diagnosed with epicardial fat necrosis (EFN) using chest CT imaging. Both cases showed elevated inflammatory markers (D-dimer, C-reactive protein) with normal troponin, and CT demonstrated characteristic EFN; symptoms resolved with nonsteroidal anti-inflammatory drugs. The significance is that EFN should be considered in the differential diagnosis of MI/PE/pericarditis-like presentations to avoid unnecessary invasive workup and to guide appropriate anti-inflammatory treatment.
Da Silva E, Chow B, Paterson DI et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac arrhythmias & arrhythmia-induced cardiomyopathy
Prevalence and characteristics of normal electrocardiograms in hypertrophic cardiomyopathy.
This retrospective study evaluated hypertrophic cardiomyopathy (HCM) patients diagnosed by European Society of Cardiology (ESC) criteria to determine the prevalence and clinical characteristics of those with a normal electrocardiogram (ECG). It focused on how patients with normal ECG relate to indicators of disease severity, addressing the diagnostic delay risk in a subgroup with milder disease. Clinically, defining how often ECG can be normal in HCM and what severity markers still apply can refine diagnostic pathways and reduce missed or delayed HCM recognition.
Guler A, Gorgulu BK, Surgit O et al. · Journal of electrocardiology · (2026) · View on PubMed ↗
Prevalence and Recovery of Arrhythmia-Induced Cardiomyopathy in Patients With Newly Diagnosed Heart Failure Using a Wearable Defibrillator: A Real-World Cohort Study.
This real-world cohort study assessed the prevalence, predictors, and outcomes of arrhythmia-induced cardiomyopathy (AIC) in 780 patients treated with a wearable cardioverter-defibrillator (WCD) from 2017–2023, focusing on newly diagnosed idiopathic left ventricular systolic dysfunction (LVEF <35%) with persistent arrhythmia (atrial fibrillation/flutter or >20% ventricular ectopy). The study evaluated how early rhythm control enabled by WCD relates to recognition and recovery of AIC in routine practice. The findings are intended to improve identification of reversible cardiomyopathy drivers and guide early management strategies in patients with LV dysfunction and ongoing arrhythmia.
Yogarajah J, Dannebaum J, Halim A et al. · Journal of cardiovascular electrophysiology · (2026) · View on PubMed ↗ · Free PDF ↗
Malignant Mitral Valve Prolapse With Life-Threatening Ventricular Arrhythmias: A Multidisciplinary Team-Guided Stepwise Management.
This case report studied malignant arrhythmogenic mitral valve prolapse (MVP) in a 45-year-old woman with bileaflet myxomatous MVP, mitral annular disjunction, and mild mitral regurgitation who developed polymorphic ventricular tachycardia and recurrent ventricular fibrillation despite medical therapy and ICD shocks. The key finding was that life-threatening ventricular arrhythmias occurred even without severe MR and without detectable myocardial fibrosis on cardiac magnetic resonance imaging, implying that electrical and mechanical risk markers can identify imminent risk. The significance is that risk stratification for MVP-related sudden cardiac death may require integrating multiple markers beyond fibrosis and MR severity to guide stepwise multidisciplinary management.
Javadi N, Jahangir A, Galazka P et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Hypertrophic Cardiomyopathy Today: Integrating Myosin Inhibition with Established Strategies.
This narrative review studied contemporary approaches to hypertrophic cardiomyopathy (HCM) by integrating advances in imaging, genetics, and therapeutics, with particular emphasis on cardiac myosin inhibitors. The key finding is a synthesis of how multimodality imaging (echocardiography and cardiac magnetic resonance) and modern risk stratification inform individualized management, including trial evidence for mavacamten and aficamten. The significance is that it provides an up-to-date framework for clinicians to apply myosin inhibition alongside established strategies for obstructive and nonobstructive HCM.
Seçkin Ö, Ünlü S · Current cardiology reviews · (2026) · View on PubMed ↗
Drug/supplement-induced cardiotoxicity (chemotherapy, supplements, toxins)
Superior anti-DLBCL efficacy of novel organic arsenical Z2-A-Z2 through ROS-mediated apoptosis and critical NF-κB/IκBα signaling pathway inhibition.
This preclinical cancer study tested the novel organic arsenical compound Z2-A-Z2 in diffuse large B-cell lymphoma (DLBCL), focusing on its effects in GCB- and ABC-subtype DLBCL cell lines and in normal peripheral blood mononuclear cells (PBMCs). Z2-A-Z2 showed superior anti-DLBCL efficacy by inducing ROS-mediated apoptosis and inhibiting the NF-κB/IκBα signaling pathway that supports lymphoma survival. The work is significant because it identifies a mechanistic therapeutic strategy targeting NF-κB signaling in a lymphoma subtype that often resists standard treatments.
Wei W, Ma Y, Liu Y et al. · Journal of experimental & clinical cancer research : CR · (2026) · View on PubMed ↗ · Free PDF ↗
Fluoropyrimidine Cardiotoxicity With Overlapping Vasospastic and Pericardial Features: A Diagnostic Challenge.
This JACC Case Reports report described a 57-year-old man with HER2-positive gastric cancer receiving FOLFOX-6M plus trastuzumab who developed severe chest pain during 5-fluorouracil (5-FU) infusion with ECG changes and marked QTc prolongation but negative cardiac biomarkers. Fourteen hours later, new concave ST-segment elevation emerged despite normal echocardiography and coronary CT angiography, illustrating overlapping vasospastic and inflammatory pericardial features as a diagnostic challenge in fluoropyrimidine cardiotoxicity. Clinically, the case emphasizes that fluoropyrimidine-induced cardiac events may evolve beyond initial biomarker negativity and require careful serial ECG/imaging assessment.
Viñas-Mendieta AE, Valencia-Hernandez HA, Ruiz-Mori E et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Myopericarditis After Combined Idarubicin and Quizartinib in FLT3-ITD-Positive AML.
This case report studied cardiotoxicity in a 64-year-old man with FLT3-ITD-positive acute myelogenous leukemia treated with cytarabine plus idarubicin followed by the FLT3 inhibitor quizartinib. The patient developed myopericarditis with fever, hypotension, troponin I elevation, diffuse ST-segment elevation, and cardiac magnetic resonance imaging late gadolinium enhancement consistent with myopericarditis. The report is clinically significant because it suggests that adding FLT3 inhibition (quizartinib) after anthracycline exposure (idarubicin) may increase risk of inflammatory myocardial/pericardial injury, warranting close cardiac monitoring in this treatment sequence.
Spahr ZR, Vasquez MA, Tangella A et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Unexplained Supraventricular Tachycardia and Myocardial Injury After Bitter Orange Supplement Use in a Young Woman.
This case report studied cardiovascular toxicity in a 38-year-old woman after using a weight-loss supplement containing bitter orange (Citrus aurantium) with p-synephrine. The patient developed supraventricular tachycardia and myocardial injury with a marked rise in high-sensitivity troponin I, with adenosine terminating the arrhythmia and subsequent evaluation excluding other causes (e.g., pulmonary embolism). The clinical significance is that sympathomimetic supplements such as p-synephrine can precipitate both arrhythmia and myocardial injury, highlighting the need for medication/supplement history and prompt cardiac assessment in similar presentations.
Plaitis A, Grigoraki E, Karakosta M et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiovascular imaging AI/automation & computational methods (CMR/CT/MRI)
Fast and scalable annotation-free LV-centered ROI localisation in stress perfusion cardiac MRI.
This engineering study developed an annotation-free pipeline for fast, scalable left ventricle (LV)-centered region-of-interest (ROI) localization in stress perfusion cardiac MRI. It found that combining Fast Fourier Transform-based localization with Sobel edge refinement and a heuristic fallback can generate consistent LV-centered ROIs directly from raw perfusion frames without task-specific labels, using a circular post-processing ROI to standardize ventricular coverage. The significance is enabling efficient, scalable stress perfusion CMR analysis when manual annotation is impractical and labeled datasets are scarce.
Kalashami MP, Fagioli A, Marini MR et al. · Computers in biology and medicine · (2026) · View on PubMed ↗
Fourier-Net+: Band-Limited Spatial Representation for Efficient Medical Image Registration.
This paper studied Fourier-Net+ for efficient medical image registration by learning a band-limited, low-dimensional representation of the displacement field rather than predicting dense full-resolution displacement maps. It found that deterministic Fourier-domain band-limiting for down/up-sampling plus a parameter-free, model-driven decoder reduces computational cost while maintaining deformable registration capability across real-valued image modalities. The significance is faster, more scalable unsupervised deformable registration for high-resolution volumetric medical imaging tasks.
Jia X, Thorley A, Gomez A et al. · IEEE transactions on neural networks and learning systems · (2026) · View on PubMed ↗
Multimodal Artificial Intelligence for Early Detection and Precision Management of Inflammatory and Infiltrative Cardiomyopathies.
This article proposes a multimodal artificial intelligence (AI) approach for early detection and precision management of inflammatory and infiltrative cardiomyopathies (including cardiac sarcoidosis, transthyretin amyloidosis, and autoimmune myocarditis). The key concept is that AI can integrate ECG, echocardiography, CMR, PET/scintigraphy, biomarkers, and electronic health record (EHR) features to improve diagnostic suspicion, tissue-based phenotyping, and risk-directed triage. Scientifically and clinically, this could shorten time to diagnosis in conditions that are often recognized only after advanced myocardial dysfunction develops.
Adrejiya P, Alkhatib DA, Aljaroudi W · Current problems in cardiology · (2026) · View on PubMed ↗
Feasibility of Magnetic Resonance Imaging-Guided Pulmonary Artery Stenting in a Commercial Wide-Bore 0.55-T Scanner.
This preclinical feasibility study tested real-time magnetic resonance imaging (MRI)-guided pulmonary artery (PA) stenting in a swine model using a commercial wide-bore 0.55-T MRI system with ferumoxytol-enhanced imaging. PA stenting was successful in 7 of 10 juvenile pigs, with all successful deployments occurring after switching from femoral to external jugular venous access, and real-time gradient-echo imaging provided sufficient visualization for catheter navigation and stent deployment. The results are significant because they support the technical feasibility of radiation-free, MRI-guided vascular interventions for complex PA procedures.
Liu Y, Kelly JM, Swinning J et al. · JACC. Basic to translational science · (2026) · View on PubMed ↗ · Free PDF ↗
Impact of formalin fixation on biventricular parameters in cardiac diffusion tensor imaging: A pilot study in a miniature swine model.
This pilot ex-vivo miniature swine study examined how formalin fixation affects biventricular cardiac diffusion tensor imaging (cDTI) parameters, using histology as the reference standard. High-resolution cDTI was acquired at baseline and days 5 and 9 after fixation, and hematoxylin-and-eosin staining on day 10 quantified helix angle (HA) and HA transmurality across 64 myocardial segments (48 LV, 16 RV). The results indicate that fixation can alter cDTI-derived microstructural metrics, which is scientifically important for standardizing and interpreting cDTI in post-mortem or histology-correlated workflows.
Zhu L, Xu J, Cui C et al. · The international journal of cardiovascular imaging · (2026) · View on PubMed ↗
Simultaneous multi-slice Cardiac Diffusion Tensor Imaging with variable CAIPIRINHA shifts and artefact-aware AI.
This study introduced ORCAS, a framework combining variable CAIPIRINHA acquisition with artefact-aware AI reconstruction to enable simultaneous multi-slice (SMS) cardiac diffusion tensor imaging (cDTI) with fewer repetitions. The method targets SMS inter-slice leakage artefacts and low signal-to-noise ratio (SNR) limitations by decohering SMS artefacts across repetitions while using AI to improve reconstruction quality. Scientifically, ORCAS aims to make in-vivo cDTI faster and more feasible for myocardial microstructure assessment without prohibitive scan times.
Tänzer M, Lim EJ, Qiu HH et al. · Medical image analysis · (2026) · View on PubMed ↗
Blood cell traits on cardiovascular morpho-functional phenotypes: evidence from Mendelian randomization analysis.
This 2-sample Mendelian randomization study used genetic instruments for 15 blood cell traits (7 red blood cell, 6 white blood cell, and 2 platelet traits) to test causal effects on 100 cardiovascular magnetic resonance (CMR) morpho-functional traits. The CMR traits were derived from seven genome-wide association studies and served as preclinical endophenotypes of cardiac chamber and aortic segment structure and function. Establishing causal links between specific blood cell traits and CMR phenotypes could inform mechanistic pathways and identify biomarkers or targets for cardiovascular disease prevention.
Li M, Zhu H, Shen L et al. · Medicine · (2026) · View on PubMed ↗ · Free PDF ↗
Quantitative ventricular trabeculation assessment in cardiac MRI: optimised blood-pool segmentation, box-counting fractal analysis and non-fractal measurements.
This methodological study optimized an automated cardiac MRI workflow for quantitative ventricular trabeculation assessment using level-set blood-pool segmentation and box-counting fractal analysis, targeting left and right ventricles at end-diastole and end-systole. The authors evaluated how box size, sampling, and rotation affect fractal dimension (FD) estimates and proposed alternative non-fractal boundary measures to improve robustness for large-scale cohort analysis. Reliable, automated trabeculation quantification could enable scalable phenotyping and longitudinal tracking of ventricular remodeling in clinical and research settings.
Sedlacik J, McGurk KA, Tokarczuk PF et al. · The international journal of cardiovascular imaging · (2026) · View on PubMed ↗ · Free PDF ↗
CardioSynth: Parameter-driven cardiac MRI generation via oriented bounding boxes.
This computer methods study introduced CardioSynth, a parameter-driven cardiac MRI generation framework using oriented bounding boxes to represent and manipulate cardiac substructures while preserving anatomical plausibility. The method encodes substructures as oriented bounding boxes and applies progressive label modification to generate synthetic images with controlled area changes. Such synthetic, controllable cardiac MRI generation could support scalable training, simulation, and research workflows without requiring repeated acquisition of real scans.
Banerjee S, Mazumder O, Sinha A · Computer methods and programs in biomedicine · (2026) · View on PubMed ↗ · Free PDF ↗
Radiomics with native T1 mapping for contrast-free detection of acute and chronic myocardial infarction: A multicenter study.
This multicenter retrospective study developed and validated contrast-free radiomics models using native T1 mapping from 3.0T cardiac MRI to detect myocardial infarction (MI) and distinguish acute from chronic lesions. Using manual ROI delineation, recursive feature elimination, and ROC-based evaluation in 310 MI patients (162 acute, 148 chronic) plus 180 controls, the authors built Model 1 for MI diagnosis and Model 2 for acute/chronic differentiation, with Model 2 externally validated. If validated further, native T1 radiomics could enable non-contrast, automated MI characterization for broader clinical use and longitudinal monitoring.
Li S, Huo H, Zheng Y et al. · International journal of cardiology · (2026) · 1 citations · View on PubMed ↗
High-precision brain tumor segmentation with switchable normalization in faster R-CNN architecture.
This study developed and evaluated a Switchable Normalization-based Faster R-CNN (SNFRC) deep learning framework for high-precision brain tumor segmentation from multi-modal MRI in heterogeneous imaging conditions. The key finding is that using switchable normalization within the region proposal network (RPN) improves feature consistency across heterogeneous data distributions and supports a detection-based segmentation approach for accurate delineation of irregular small tumors. The work is significant for clinical imaging workflows because it targets robust, high-accuracy segmentation without requiring separate models for each data distribution or protocol.
Kumar DR, Reddy PV, Mohammad H et al. · Scientific reports · (2026) · View on PubMed ↗ · Free PDF ↗
Development and validation of a versatile foundation model for cine cardiac magnetic resonance image analysis.
This study developed and validated CineMA, a versatile foundation model for cine cardiac magnetic resonance (CMR) image analysis, pre-trained on 15 million cine CMR images from 74,916 studies and then fine-tuned for multiple tasks. The key finding is that the multi-view conv-transformer masked autoencoder foundation model can be fine-tuned and evaluated across eight independent datasets for segmentation, landmark localization, and disease-related measurements, reducing the need to train separate task-specific models from scratch. The clinical significance is improved efficiency and reproducibility for extracting CMR measurements that are currently time-consuming and subjective, potentially accelerating scalable CMR-based care and research.
Fu Y, Bai W, Yi W et al. · Communications medicine · (2026) · View on PubMed ↗ · Free PDF ↗
Epidemiology, public health, and real-world outcomes (EHR/cohorts/trends)
Measurement of quality of stroke care with national electronic health records: a prospective cohort study during and after the COVID-19 pandemic.
This prospective England-wide cohort study used linked national electronic health records (including SSNAP, primary/secondary care, dispensed medications, and mortality data) to evaluate stroke care quality before and after the COVID-19 pandemic in 425,675 adults. It focused on metrics not routinely captured, including stroke incidence, secondary prevention medication dispensing, and a proxy for disability-time spent at home (“home-time”). The scientific significance is validating EHR linkage as a scalable way to quantify real-world stroke care quality and disability-related outcomes across system disruptions.
Farrell J, Nolan J, Lambert R et al. · BMJ open · (2026) · View on PubMed ↗
Arteriovenous fistula creation results in cardiac dysfunction and remodeling in a uremic pig model.
This preclinical study investigated cardiovascular effects of arteriovenous fistula (AVF) creation in a uremic pig model of end-stage kidney disease, including AVF creation supported by percutaneous transluminal angioplasty (PTA). It found that AVF creation led to cardiac dysfunction and remodeling, establishing a large-animal model to study mechanisms linking AVF-induced hemodynamic changes to adverse cardiac outcomes. The significance is providing a translational platform to test interventions that could reduce cardiac morbidity in dialysis patients.
Kane J, Singh PG, Kilari S et al. · American journal of physiology. Renal physiology · (2026) · View on PubMed ↗
Trends and Projections for Aortic Stenosis and Hypertension-Related Mortality Among Older Adults in the United States: A Retrospective Population-Based Analysis.
This retrospective population-based analysis studied trends and projections of mortality among older U.S. adults with comorbid aortic stenosis (AS) and hypertension (HTN) from 1999–2020 using CDC WONDER multiple cause-of-death data. It found that mortality patterns differed by demographic-geographic factors and used joinpoint regression (APC/AAPC) plus ARIMA-based projections to estimate future mortality through 2030. The significance is informing public health planning by quantifying how combined AS+HTN burden evolves over time and where disparities may widen.
Bhatti MI, Safiullah M, Farhan K et al. · High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · (2026) · View on PubMed ↗
Determining adverse childhood experiences and their association with substance use among young adults in universities and colleges in Mombasa County, Kenya.
This cross-sectional study assessed adverse childhood experiences (ACEs) and their association with substance use (alcohol, tobacco products, and illicit drugs) among 849 young adults sampled from universities and colleges in Mombasa County, Kenya. It investigated whether participants who reported ACEs were more likely to report substance use, using self-reported exposure and outcome measures. The findings are important for public health and prevention planning by clarifying how early-life adversity may contribute to later substance use in young adults.
Odero M, Kihoro RW, Mbogo PW et al. · Substance abuse treatment, prevention, and policy · (2026) · View on PubMed ↗ · Free PDF ↗
Epidemiology of non-ischaemic dilated cardiomyopathy.
This Nature Reviews Cardiology article synthesizes evidence on the epidemiology of non-ischaemic dilated cardiomyopathy (DCM), defined by left ventricular dilatation and systolic dysfunction, with emphasis on prevalence estimates derived from cardiac magnetic resonance (CMR) studies. It reports that non-ischaemic DCM is more common than previously thought (around 1 in 220) and appears about twice as prevalent in men as in women, with prevalence potentially higher when early/subclinical disease is included. The review is significant because it frames how improved imaging and genetic technologies are reshaping understanding of disease burden and risk across age groups.
Ramos-López N, Domínguez F, Ochoa JP et al. · Nature reviews. Cardiology · (2026) · View on PubMed ↗
Subclinical Origins of Cardiometabolic Risk in Indian Adolescents: A Cross-Sectional Study.
This cross-sectional study measured anthropometry, hepatic fat, and cardiometabolic risk factors in apparently healthy Indian adolescents aged 11–16 years using 3.0T MRI proton density fat fraction (PDFF) and whole-body fat by dual-energy X-ray absorptiometry (DXA). The study found cardiometabolic risk factors were present in about one-third of participants (32.5% reported with at least one CMR factor, with results truncated in the abstract). These findings suggest that subclinical cardiometabolic risk is already detectable in early adolescence and may be linked to body and hepatic fat, supporting earlier screening and prevention strategies in youth populations.
Hegde SG, Kankara SR, Raj JM et al. · Indian pediatrics · (2026) · View on PubMed ↗
Naïve CD4+ T-cells and disease status at CART infusion correlate with clinical outcomes in real-world large B-cell lymphoma patients receiving second-line CAR T therapy.
This retrospective real-world study evaluated 64 patients with relapsed/refractory large B-cell lymphoma receiving second-line commercial CAR T therapy with either axicabtagene ciloleucel (axi-cel) or lisocabtagene maraleucel (liso-cel), focusing on how naïve CD4+ T-cell levels and disease status at CAR T infusion relate to outcomes. Primary refractory disease and progressive disease at infusion were associated with inferior response rates, while overall and complete response rates were similar between axi-cel and liso-cel. These findings suggest that baseline immune composition (naïve CD4+ T-cells) and disease burden at infusion can help refine prognostication for second-line CAR T in routine practice.
Schneider M, Paruzzo L, Stella F et al. · Nature communications · (2026) · View on PubMed ↗ · Free PDF ↗
Unmasking subclinical cardiomyopathy: The role of cardiopulmonary exercise testing when screening genotype-positive phenotype negative relatives.
This single-center case series studied whether cardiopulmonary exercise testing (CPET) can unmask subclinical cardiomyopathy among gene-positive, phenotype-negative (G+P-) relatives in families undergoing cascade testing for likely/definite pathogenic cardiomyopathy variants. The key finding was the added diagnostic value of CPET in detecting abnormalities not evident on conventional screening (ECG, echocardiography, Holter monitoring, and cardiac MRI) in younger, phenotype-negative individuals. The clinical significance is that CPET may improve risk detection and surveillance strategies for relatives carrying cardiomyopathy genes but lacking overt structural/functional disease on standard tests.
Abela M, Scicluna J, Debattista J et al. · International journal of cardiology · (2026) · View on PubMed ↗
Canadian radiology: 2026 update.
This narrative update reviewed selected Canadian radiology research across subspecialties, including abdominal and cardiothoracic imaging, and highlighted system-level developments in practice and delivery. It reports notable advances such as disease-specific oncologic imaging guidance and updated approaches to contrast media hypersensitivity, alongside contributions to cardiac magnetic resonance and opportunistic cardiovascular imaging. The review is significant for clinicians and researchers because it consolidates evolving evidence and practical imaging guidance relevant to Canadian care pathways.
Kamran R, Buckley B, Costa AF et al. · Diagnostic and interventional imaging · (2026) · View on PubMed ↗ · Free PDF ↗
From Healthy to Heart Failure in 24 Hours: Defining the upper limit of exercise induced cardiac fatigue.
This single-athlete study examined the cardiac consequences of 12-hour and 24-hour intense cycling in a former professional ultra-endurance athlete using echocardiography, rest and exercise cardiac MRI, and biomarkers (BNP and cardiac troponin-I). After the 12-hour attempt and the 24-hour attempt, the athlete showed measurable cardiac fatigue/functional and biomarker changes consistent with an upper limit of exercise-induced cardiac stress. The findings are important for sports physiology and cardiology because they help define how extreme endurance exercise can transiently affect cardiac structure/function and injury markers.
Foulkes SJ, Anderson M, Janssens K et al. · Journal of applied physiology (Bethesda, Md. : 1985) · (2026) · View on PubMed ↗ · Free PDF ↗
Generated automatically on May 20, 2026. Covers PubMed articles published May 13, 2026 – May 20, 2026. Summaries are AI-generated; always consult the original publication for clinical or research decisions.