What's New in Cardiac MRI? — May 26, 2026
AI-summarised digest of 63 PubMed articles on Cardiac MRI published in the last 7 days.
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What’s New in Cardiac MRI?
May 26, 2026 · 63 articles · 15 research themes · covering May 19, 2026 – May 26, 2026
Overview
Across this week’s papers, cardiovascular risk is increasingly being framed through “tissue and physiology” rather than just symptoms or ejection fraction. Multiple studies use CMR-derived fibrosis and remodeling signals—ranging from diffuse fibrosis patterns in aortic stenosis, noninfarcted myocardium changes after MI, and myocardial elasticity after infarction, to insulin-resistance–linked fibrosis and heart-failure incidence—to show that clinically accessible markers can identify patients at risk earlier. In parallel, phenotype-based approaches (e.g., CMR remodeling clusters after STEMI; metabolic health/obesity phenotypes modifying CMR outcomes) suggest that prognosis improves when we stratify by underlying biology rather than single thresholds.
A second dominant theme is the expanding role of CMR (often with PET/CT or CT) in complex inflammatory and non-atherosclerotic cardiac disease. Recurrent myocarditis, Chagas cardiomyopathy, cardiac sarcoidosis, lupus myocarditis, eosinophilic heart disease, and even rare entities like cardiac lymphoma and metastatic neuroendocrine tumors all highlight a common message: tissue characterization and multimodality workflows reduce diagnostic uncertainty when presentations mimic ACS or cardiomyopathy. Diagnostic accuracy is further supported by advances in imaging protocols (ultrafast pediatric CMR, standardized T1 mapping) and by AI/automation that improves measurement consistency and scales CMR analysis.
Finally, the digest reflects a broader shift toward mechanistic and translational cardiology—linking imaging to hemodynamics, arrhythmia risk, and systemic pathways. Examples include CMR hemodynamic force metrics predicting MACE during immune checkpoint inhibitor therapy, right-heart diastolic dysfunction conceptualized as a unified “diastolic unit,” metabolomic signatures tied to RV dysfunction in pulmonary vascular disease, and gene-pathway or channel-target strategies (e.g., FHF–INa,L) aimed at arrhythmia prevention. Together, these studies point to a future where imaging, biomarkers, and computational tools converge to enable earlier detection, better phenotyping, and more personalized management.
Cardiac MRI for Cardiomyopathies & Genetic Disease
Fast and scalable annotation-free LV-centered ROI localisation in stress perfusion cardiac MRI.
The study developed and evaluated an annotation-free pipeline for left ventricle (LV)-centered region-of-interest (ROI) localisation in stress perfusion cardiac MRI, using raw perfusion frames from cardiac MRI datasets. The method combined Fast Fourier Transform-based localisation with Sobel edge refinement and a heuristic fallback to generate consistent circular LV-centered ROIs without task-specific labels. This scalable approach can reduce the need for manual annotation and accelerate stress perfusion CMR analysis workflows for research and potentially clinical imaging pipelines.
Kalashami MP, Fagioli A, Marini MR et al. · Computers in biology and medicine · (2026) · View on PubMed ↗
Cone reconstruction for EBSTEIN anomaly: Effect on tricuspid valve growth and biventricular remodeling in children.
This retrospective study evaluated cone reconstruction (CR) surgery in 17 children (<18 years) with Ebstein anomaly (Carpentier types A–C) and assessed effects on tricuspid valve growth and biventricular remodeling using echocardiography and cardiac magnetic resonance imaging (CMR). The key findings (as reported in the abstract) indicate no operative mortality and provide postoperative assessment of tricuspid valve and biventricular size/function changes over follow-up. These results support CR as a surgical option influencing right-sided valve development and overall ventricular remodeling in pediatric Ebstein anomaly.
Lee JH, Kim WH, Baek SM et al. · Interdisciplinary cardiovascular and thoracic surgery · (2026) · View on PubMed ↗
Epicardial adipose tissue is associated with impaired outcomes in genotype-positive hypertrophic cardiomyopathy.
This retrospective study quantified epicardial adipose tissue (EAT) volume by cardiovascular magnetic resonance in a genotype-positive hypertrophic cardiomyopathy (HCM) cohort and related EAT (high vs low by median) to malignant ventricular arrhythmias (MVA) and heart failure outcomes using multivariable Cox regression. Higher EAT volume was associated with impaired clinical outcomes, including increased risk of MVA and worse prognosis in genotype-positive HCM patients. These findings support EAT as a potentially actionable imaging biomarker for risk stratification beyond genotype in HCM.
Mahmoud B, Koppelaar AJ, Michels M et al. · European journal of heart failure · (2026) · View on PubMed ↗ · Free PDF ↗
Prognostic Impact of LGE Granularity Using CMR in End‑Stage Hypertrophic Cardiomyopathy.
This retrospective multicenter study evaluated prognostic value of late gadolinium enhancement (LGE) granularity features—incorporating location, extent, and pattern—on cardiovascular magnetic resonance in patients with end-stage hypertrophic cardiomyopathy (HCM) defined by left ventricular ejection fraction <50%. LGE granularity metrics were assessed for association with adverse outcomes in this high-risk population. If validated, LGE granularity could improve CMR-based risk prediction in end-stage HCM beyond conventional LGE presence/extent.
Hudelo J, Garot J, Toupin S et al. · Circulation. Cardiovascular imaging · (2026) · View on PubMed ↗
Natural history of cardiac involvement in women carrying pathogenic DMD gene variants: a 7-year longitudinal study.
This 7-year longitudinal study examined the natural history of cardiac involvement in women carrying pathogenic dystrophin (DMD) gene variants (Duchenne- and Becker-associated). It found that over follow-up, cardiac magnetic resonance (CMR) assessments tracked evolution of ventricular function, myocardial fibrosis, and arrhythmias in this genetically defined population. Scientifically and clinically, the results support better long-term surveillance strategies for cardiomyopathy and conduction abnormalities in female DMD carriers.
Lyu Z, Joensen H, Poulsen NS et al. · Journal of neurology · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac MRI in cardiac dystrophinopathy: recommendations on imaging.
This article provided expert recommendations on cardiac MRI (CMR) for cardiac dystrophinopathy, focusing on patients with Duchenne muscular dystrophy (DMD). It found that compared with echocardiography, CMR better detects myocardial tissue changes before measurable decline in pump function and maintains measurement accuracy as DMD progresses. Clinically, the recommendations support more sensitive and reliable imaging surveillance to guide heart-drug treatment in DMD.
McDiarmid A, Augustine D, Coats C et al. · Open heart · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac MRI for Inflammatory Myocardial Diseases
[Chagas cardiomyopathy].
This review studied chronic Chagas cardiomyopathy in patients with Trypanosoma cruzi infection, focusing on how cardiovascular imaging detects early myocardial involvement. It found that echocardiography best assesses cardiac function and structural abnormalities, while cardiac magnetic resonance (CMR) enables tissue characterization and identification of myocardial fibrosis, improving diagnosis and risk stratification. Clinically, these imaging approaches support earlier detection of a disease that often progresses silently for decades and can culminate in heart failure and sudden cardiac death.
Redzepi B, Mainta I, Jackson Y et al. · Revue medicale suisse · (2026) · View on PubMed ↗
[Cardiac sarcoidosis in 2026 : current perspectives].
This review studied cardiac sarcoidosis in patients with systemic sarcoidosis, emphasizing diagnostic pathways and imaging in symptomatic cases. It found that endomyocardial biopsy has limited sensitivity (~20%), so advanced imaging—particularly [18F]-fluorodeoxyglucose positron emission tomography/computed tomography ([18F]FDG PET/CT) and cardiac magnetic resonance (CMR)—is central for prompt and accurate detection. The scientific significance is improved diagnostic sensitivity for a condition that can present with atrioventricular block, ventricular tachycardia, heart failure, and sudden cardiac death.
Sritharan A, Hermann Kamani C, Lu H et al. · Revue medicale suisse · (2026) · View on PubMed ↗
Multimodality Imaging in Inflammatory Cardiac Disease.
This narrative review studied multimodality imaging strategies for inflammatory cardiac diseases, including myocarditis, cardiac sarcoidosis, infective endocarditis, and pericarditis. It found that echocardiography is first-line for many scenarios (e.g., endocarditis and pericardial effusion), CMR provides gold-standard tissue characterization for myocarditis and cardiac sarcoidosis, and CT/FDG PET/CT add complementary anatomic and inflammatory information. The significance is optimized diagnostic accuracy and management planning across heterogeneous inflammatory etiologies.
Mahmood A, Ramesh J, Patel DS et al. · Cardiology in review · (2026) · View on PubMed ↗
Insights Into the Natural History of Recurrent Myocarditis, A Multicenter International Study (Re-Myo Study).
This multicenter international study characterized the natural history and outcomes of recurrent acute myocarditis (Re-AM) in 141 patients (median age 35 years, 77% male) with biopsy- or cardiac MRI–proven recurrence, compared with 372 patients with a single acute myocarditis episode. Re-AM patients experienced worse clinical outcomes, with the study’s primary composite endpoint including all-cause mortality, heart transplant, and major ventricular arrhythmias. Clinically, the results emphasize that recurrent myocarditis is not benign and warrants closer longitudinal monitoring and risk stratification after recurrence.
Baggio C, Cannata A, Gasperetti A et al. · Journal of the American Heart Association · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac MRI for Ischemia, MINOCA & Microvascular Dysfunction
Prognostic Implications of Coronary Microvascular Dysfunction in ST-Elevation Myocardial Infarction by Obesity Status.
This multicentre prospective cohort study evaluated coronary microvascular dysfunction (CMD) in 497 ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI), stratified by obesity status using BMI categories. CMD was defined by an angiography-derived index of microcirculatory resistance (angio-IMR) > 40 U, and the study assessed how CMD prognosis differed across obesity groups. The findings aim to clarify whether obesity modifies the long-term cardiovascular risk associated with CMD after STEMI, informing more personalized post-PPCI management.
Guo Q, Guo Y, Shi S et al. · Diabetes, obesity & metabolism · (2026) · View on PubMed ↗
Coronary artery Ectatic/Aneurysmatic disease: From pathophysiology to management.
This narrative review examined coronary artery ectatic/aneurysmatic disease (CAE/CAA), focusing on its multifactorial pathophysiology (atherosclerosis, genetic predisposition, systemic autoimmunity, and infectious triggers) and diagnostic/management approaches across adult and pediatric etiologies (e.g., connective tissue disorders, Kawasaki disease, MIS-C). CAE/CAA is associated with increased risks of thrombosis, embolization, and acute coronary syndromes even without obstructive coronary artery disease. Clinically, recognizing CAE/CAA mechanisms and tailoring management is important to prevent thromboembolic and ischemic events in affected patients.
Markousis-Mavrogenis G, Ebrahimihoor E, Lima JAC et al. · Progress in cardiovascular diseases · (2026) · View on PubMed ↗
Myocardial Infarction With Nonobstructive Coronary Arteries With Coronary Microvascular Dysfunction Associated With Systemic Sclerosis: Case Report.
This case report described myocardial infarction with nonobstructive coronary arteries (MINOCA) due to coronary microvascular dysfunction (CMD) associated with systemic sclerosis (SSc), using invasive coronary physiology testing including index of microvascular resistance (IMR) and coronary flow reserve (CFR) alongside cardiac magnetic resonance (CMR). The report highlights that SSc-related small-vessel vasculopathy can produce MINOCA mechanisms that are confirmed by invasive testing and CMR rather than by obstructive coronary disease. Clinically, it underscores the value of coronary function testing and CMR in SSc patients presenting with MINOCA to guide diagnosis and management.
Ohga Y, Nishikawa T, Hirai A et al. · Case reports in vascular medicine · (2026) · View on PubMed ↗ · Free PDF ↗
Pre-perfusion coronary wedge pressure and microvascular obstruction in anterior ST elevation myocardial infarction (STEMI): An analysis from the EUROICE study.
This EUROICE study analysis investigated whether pre-perfusion coronary wedge pressure (CWP) measured during balloon occlusion relates to microvascular obstruction (MVO) in anterior ST-elevation myocardial infarction (STEMI). The study focused on microvascular injury assessed by CMR as MVO, addressing the limitation that commonly used invasive indices like IMR are obtained after reperfusion and may miss microvascular compromise during occlusion. The work is significant because it evaluates an earlier, simpler invasive marker (CWP) for risk stratification tied to CMR-defined microvascular injury.
Butt H, van Beek K, Sajjad U et al. · International journal of cardiology · (2026) · View on PubMed ↗
Layer-specific fast strain-encoded cardiovascular magnetic resonance in suspected acute coronary syndrome: a prospective study.
This prospective observational study evaluated whether layer-specific fast strain-encoded cardiovascular magnetic resonance (fSENC) can identify ischemic causes in patients with suspected acute coronary syndrome. It found that patients with chest pain and low-to-intermediate pretest probability underwent rapid CMR before further therapy, using layer-specific strain analysis to better characterize myocardial injury patterns beyond early troponin-detected injury. Clinically, the approach may improve noninvasive triage by distinguishing coronary plaque rupture requiring invasive management from other causes of myocardial injury.
Weberling LD, Siry D, Haney AC et al. · Clinical research in cardiology : official journal of the German Cardiac Society · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac MRI for Myocardial Fibrosis, Remodeling & Heart Failure Risk
Filamin C Genetic Cardiomyopathy Presenting as Acute Myocardial Injury.
This JACC Case Reports report described a 46-year-old man with acute myocardial injury characterized by nonischemic imaging, in whom genetic testing identified a pathogenic FLNC (filamin C) variant. Cardiac MRI showed extensive ring-like subepicardial late gadolinium enhancement across 10 LV segments with no myocardial edema, and follow-up at 4 months demonstrated persistent fibrosis with preserved ventricular function and no arrhythmias. The case is significant because it links a specific FLNC genetic cardiomyopathy phenotype to a distinctive ring-like LGE pattern that can aid diagnosis in acute myocardial injury presentations.
Alexandrino FB, Curtis B, Nguyen C et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Rethinking Post-Infarction Remodeling: Identification and Validation of Data-Driven Cardiac MRI Phenotypes for Risk Stratification.
This prospective longitudinal study used unsupervised clustering on serial cardiac MRI (CMR) data to identify and validate data-driven left ventricular remodeling phenotypes after reperfused STEMI. In a derivation cohort (n=337) and independent validation cohort (n=190), patients underwent CMR at <7 days and at 6 months, and the resulting remodeling phenotypes were designed to improve prognostic stratification beyond conventional adverse LV remodeling definitions based on end-diastolic volume index and ejection fraction. This approach is significant because it may enable more accurate, phenotype-based prediction of outcomes after STEMI using routine CMR follow-up.
Xiang JY, Wu J, Zhao Y et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗
Changes in myocardial elasticity derived from in-vivo cardiac MRI in a swine model of ischemic heart failure.
This in-vivo preclinical study used a clinically relevant swine model of ischemic heart failure after myocardial infarction (MI) to derive myocardial elasticity (secant modulus) from cardiac MRI (wall stress–wall strain analysis). The key finding was that secant modulus measured by CMR captured myocardial remodeling changes beyond what is typically assessed by left ventricular ejection fraction (EF), potentially detecting early mechanical alterations after MI. This suggests CMR-derived myocardial elasticity could serve as a more sensitive imaging biomarker for progression and early detection of post-MI heart failure.
Lefkowitz E, Ref J, Bravo F et al. · Scientific reports · (2026) · View on PubMed ↗ · Free PDF ↗
Distribution of diffuse myocardial fibrosis is uneven and associated with left ventricular function in severe aortic stenosis.
This study investigated diffuse myocardial fibrosis (DMF) distribution and its relationship to left ventricular (LV) function in patients with severe aortic stenosis using CMR and myocardial biopsy. It found that DMF distribution was uneven across the myocardium and that CMR tissue characteristics of DMF were associated with LV functional impairment. The significance is improved understanding of which fibrosis patterns are linked to worse cardiac performance and may inform prognosis and potential reversibility after surgery.
Holmberg E, Engvall J, Nylander E et al. · Open heart · (2026) · View on PubMed ↗ · Free PDF ↗
Multiparametric Cardiac Magnetic Resonance Characterization of the Noninfarcted Myocardium: Definition, Assessment, and Clinical Significance.
This review studied the noninfarcted myocardium (NIM) after acute myocardial infarction (AMI) and how multiparametric CMR characterizes its functional, structural, and inflammatory changes. It found that CMR can detect NIM alterations such as inflammation, interstitial expansion, and altered myocardial deformation, extending assessment beyond infarct size and peri-infarct regions. The clinical significance is that NIM characterization may better explain post-AMI remodeling and risk, potentially guiding prognosis and therapy targeting the broader myocardium.
Pavon AG, Bergamaschi L, Guglielmo M et al. · JACC. Cardiovascular imaging · (2026) · View on PubMed ↗
Structural and Functional Abnormalities in the Preterm Heart: From Development to Adulthood.
This review synthesized evidence on structural and functional abnormalities in the preterm heart, linking disrupted development (e.g., oxygen exposure, extracellular matrix changes, cardiomyocyte mitochondrial dysfunction, and immature sarcoplasmic/endoplasmic reticulum) to increased cardiovascular disease risk in adulthood. It emphasizes that even when preterm infants have structurally normal hearts, developmental insults can produce long-term cardiovascular vulnerability. The clinical significance is that it supports heightened surveillance and early risk stratification strategies for individuals born preterm.
Zegelbone P, Young K, Hughes F et al. · Journal of the American Heart Association · (2026) · View on PubMed ↗ · Free PDF ↗
Glucose Disposal Rate: A Novel Measure of Insulin Resistance Associated With Myocardial Fibrosis and Incident Heart Failure.
This study evaluated whether the estimated glucose disposal rate (eGDR), a surrogate measure of insulin resistance derived from body mass index, hypertension, and hemoglobin A1c, is associated with myocardial fibrosis and incident heart failure in 6,025 MESA participants without heart failure. Lower eGDR (greater insulin resistance) was linked to greater myocardial fibrosis and a higher risk of developing heart failure during follow-up. These findings support using eGDR as a clinically accessible cardiometabolic risk marker to identify individuals at risk for insulin-resistance–related myocardial remodeling and future heart failure.
Bukhari S, Kwapong YA, Yanek LR et al. · Journal of the American Heart Association · (2026) · View on PubMed ↗ · Free PDF ↗
Associations of Metabolic Phenotypes with Cardiac Structure and Clinical Outcomes: Insights from the UK Biobank.
Using UK Biobank data, this prospective cohort study examined how metabolic phenotypes—metabolically healthy nonobese (MHN) vs obese (MHO) and metabolically unhealthy nonobese (MUN) vs obese (MUO)—relate to cardiac structure assessed by cardiac magnetic resonance imaging and to subsequent clinical outcomes over a median 5.1-year follow-up in 22,789 participants. Metabolically unhealthy phenotypes, particularly when combined with obesity (MUO), were associated with more adverse cardiac structural findings on CMR and worse clinical outcomes than metabolically healthy groups. These results refine cardiovascular risk stratification by showing that metabolic health status modifies the impact of obesity on cardiac remodeling and prognosis.
Bogner B, Jung M, Reisert M et al. · The Journal of clinical endocrinology and metabolism · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗
Cardiac MRI for Valvular Heart Disease (Aortic Valve)
Contemporary Overview of Aortic Regurgitation in Young Individuals: Insights From Real-Life Evidence.
This review summarized real-world evidence on aortic regurgitation (AR) in young adults (18–44 years), focusing on under- or misdiagnosis and the role of severity, etiology, early left ventricular dysfunction, and intervention strategy in prognosis. It highlights that echocardiography remains the primary imaging tool while multimodality assessment and emerging left ventricular structural/functional thresholds may improve timing of surgery in asymptomatic chronic AR. The significance lies in improving diagnostic accuracy and refining risk-based management to prevent progression and adverse outcomes in younger AR patients.
Sozzi FB, Gamberini G, Kim JK et al. · Journal of the American Heart Association · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac MRI for Right Heart Function & Pulmonary Vascular Disease
Hemodynamic and metabolomic responses to infusion of GLP-1 agonist exenatide in pulmonary arterial hypertension.
In a first-in-disease clinical study, investigators infused the GLP-1 receptor agonist exenatide intravenously during right heart catheterization in 17 patients with idiopathic pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH), and also tested acute effects in a monocrotaline (MCT) PAH rat model with cardiac magnetic resonance. Exenatide was well tolerated and acutely reduced mean pulmonary artery pressure, with multisite metabolite sampling showing metabolomic changes accompanying the hemodynamic response. The results suggest GLP-1 agonist therapy may have rapid, biologically linked pulmonary vascular effects in PAH/CTEPH and justify further mechanistic and clinical trials.
Samaranayake CB, Niglas M, Baxan N et al. · JCI insight · (2026) · View on PubMed ↗ · Free PDF ↗
Right Heart Diastology, Where Are We Now?
This 2026 review synthesized current evidence on right heart diastolic dysfunction across pulmonary vascular disease, heart failure, and congenital heart disease, reframing it as a unified “diastolic unit” involving right atrial function, right ventricular compliance, and pulmonary arterial load. The authors argue that abnormalities in relaxation and compliance often precede overt right systolic failure and are mediated by load-dependent mechanisms. Clinically, this reframing supports earlier detection and more consistent measurement of right heart diastolic dysfunction to improve prognosis and phenotyping.
Kocx CJ, Hemnes AR, Healy J et al. · Circulation research · (2026) · View on PubMed ↗ · Free PDF ↗
Metabolomics of Right Ventricular Function in Pulmonary Hypertension.
Using the multicenter PVDOMICS (Pulmonary Vascular Disease Phenomics) cohort, this study performed metabolomic analyses to identify metabolites and pathways associated with right ventricular (RV) systolic function, stratifying associations by pulmonary vascular resistance, pulmonary hypertension group 1 status, and sex. RV systolic function was quantified using fractional area change (echocardiography), global longitudinal strain (echocardiography), and ejection fraction (cardiac magnetic resonance), and regression models adjusted for age, sex, body mass index, and PH group. The work links specific circulating metabolic signatures to RV dysfunction across pulmonary hypertension phenotypes, informing mechanistic hypotheses and potential biomarkers beyond group 1 disease.
Chacon-Barahona J, Chung SJ, Garry JD et al. · Circulation research · (2026) · 1 citations · View on PubMed ↗
The relationship between myocardial and hepatic T1 relaxometry on cardiovascular magnetic resonance imaging and clinical outcomes late after tetralogy of Fallot repair.
In adults with repaired tetralogy of Fallot (rTOF) and healthy controls, this prospective study measured myocardial and hepatic native T1 relaxometry and calculated extracellular volume fraction (ECV) on cardiovascular magnetic resonance, then related these diffuse fibrosis surrogates to clinical outcomes. Patients were categorized by residual hemodynamic load (pulmonary stenosis and/or pulmonary regurgitation), and the study assessed whether myocardial and hepatic parametric imaging metrics were associated with and prognostic for late outcomes. The findings support the concept that combined myocardial–hepatic CMR biomarkers may reflect systemic disease burden after rTOF repair.
Ishikita A, Marques L, Thomas S et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
Arteriovenous fistula creation results in cardiac dysfunction and remodeling in a uremic pig model.
This experimental study used a uremic pig model of chronic kidney disease induced by renal embolization to test whether arteriovenous fistula (AVF) creation (supported by percutaneous transluminal angioplasty, PTA) causes cardiac dysfunction and remodeling. AVF creation produced cardiovascular changes consistent with impaired cardiac function and structural remodeling in the uremic setting. The findings are clinically important because they provide a large-animal mechanistic model for AVF-associated cardiovascular risk in end-stage kidney disease (ESKD) patients.
Kane J, Singh PG, Kilari S et al. · American journal of physiology. Renal physiology · (2026) · View on PubMed ↗
Cardiac Imaging Biomarkers & Tissue Characterization (General)
Validation of a novel three-dimensional ultrafast cardiac magnetic resonance imaging protocol in adolescents: a non-inferiority study compared with the two-dimensional gold standard.
This non-inferiority study validated a novel three-dimensional (3D) ultrafast cardiac MRI protocol against a conventional two-dimensional (2D) gold-standard protocol in adolescents. The key finding was that the 3D ultrafast approach provided non-inferior performance for assessing cardiac function, strain, and tissue characterization compared with the 2D protocol at 3-T in 39 adolescents (mean age ~12 years). This supports shorter, fewer-breath-hold CMR acquisition strategies to improve feasibility and maintain diagnostic accuracy in pediatric imaging.
Chen W, Liu S, Li W et al. · Pediatric radiology · (2026) · View on PubMed ↗ · Free PDF ↗
T1 Mapping In Differentiating Healthy And Pathological Myocardium.
This retrospective CMR study evaluated native T1 mapping measurement location and technique at 1.5T to standardize native T1 assessment, comparing non-ischemic dilated cardiomyopathy (NIDCM) and hypertrophic cardiomyopathy (HCM) against controls. The key finding was that specific native T1 mapping approaches and measurement locations provided better diagnostic discrimination between healthy myocardium and pathological myocardium in these cohorts. This helps establish a standardized, reproducible T1 mapping protocol to improve CMR-based differentiation of cardiomyopathies.
Bozer Uludağ S, Ünal S, Peker E et al. · Anatolian journal of cardiology · (2026) · View on PubMed ↗ · Free PDF ↗
Multimodality Imaging for Cardiac Masses & Tumors
Unveiling the invisible: the role of multimodality imaging in diagnosing primary cardiac lymphoma.
This article used a clinical multimodality imaging case to illustrate diagnostic challenges of primary cardiac lymphoma (PCL) and how imaging can differentiate it from mimicking conditions. In a 54-year-old woman with ACS-like presentation and a peri-atrial mass on transthoracic echocardiography, cardiac CT ruled out coronary artery disease and instead showed a hypodense process with an “encasement sign” around the left circumflex artery, supporting PCL suspicion. The report emphasizes that multimodality imaging is critical for recognizing PCL when presentations are nonspecific and can be mistaken for acute coronary syndromes.
Aronovich A, Sarid N, Hirsh M et al. · The international journal of cardiovascular imaging · (2026) · View on PubMed ↗
Left Ventricular Metastasis from Hepatocellular Carcinoma Presenting With Systemic Embolization and Stroke.
This case report described a 71-year-old man with prior hepatocellular carcinoma (HCC) who presented with systemic embolization and stroke, ultimately found to have a left ventricular (LV) metastasis. Transthoracic echocardiography suggested an LV mass initially thought to be thrombus, while cardiac MRI supported metastatic involvement, explaining the multifocal infarcts. The case is clinically important because it demonstrates a rare pathway of HCC to the LV that can present as embolic stroke and may be missed without advanced cardiac imaging.
Rashwan R, Kholeif Z, Vega-Sanabria B et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
New-Onset Atrial Flutter Revealing a Large Right Coronary Artery to Superior Vena Cava Fistula.
This JACC Case Reports report describes a 63-year-old man presenting with palpitations, hypotension, and atrial flutter with rapid ventricular response, in whom multimodality imaging identified a large right coronary artery-to-superior vena cava (RCA–SVC) fistula. Coronary computed tomography angiography and cardiac magnetic resonance demonstrated the fistula with right-sided chamber dilation, and cardiac catheterization confirmed the diagnosis followed by successful transcatheter coil embolization. The case highlights that coronary artery fistulas can present with atrial arrhythmias and that CT/CMR plus catheter confirmation can guide minimally invasive treatment.
Acharya S, Patel V, Shahane S et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Giant Cardiac Glomangioma With Extensive Intravascular Extension: A Surgical and Pathological Rarity.
This case report describes a patient with a giant cardiac glomangioma showing extensive intravascular extension from the right ventricular free wall into the right atrium and inferior vena cava, reaching the left common iliac vein. The tumor was successfully treated with surgical excision with an excellent clinical outcome. The rarity and anatomic extent emphasize the value of multimodality imaging for diagnosis and surgical planning in unusual cardiac tumors.
Bhutta M, Tariq K, Iqtadar R et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Diagnostic Accuracy of an Integrated Multimodality Imaging Approach in Patients With Cardiac Masses.
This prospective diagnostic accuracy study evaluated integrated multimodality imaging—echocardiography-derived multiparametric scores, cardiac MRI (CMR), cardiac CT (CCT), and 18F-FDG PET—among patients with suspected cardiac masses, using histology as the reference standard for malignant versus benign disease. The key finding was that combining multiparametric scores across modalities improved identification of malignant cardiac masses compared with single-modality scoring. This supports a more accurate, histology-anchored multimodality imaging workflow for risk stratification of suspected cardiac tumors.
Angeli F, Armillotta M, Foà A et al. · JACC. Cardiovascular imaging · (2026) · View on PubMed ↗ · Free PDF ↗
Rare presentation of right ventricular myxoma causing severe anaemia and acute kidney injury.
This BMJ Case Reports report described a 53-year-old man with a rare right ventricular myxoma presenting with severe anemia and acute kidney injury. The key finding was that multimodal evaluation—including transthoracic and transoesophageal echocardiography, CT with FDG PET, cardiac MRI, and endomyocardial biopsy—enabled diagnosis of the intracardiac mass prior to surgical excision and tricuspid valve repair. This highlights the diagnostic complexity of right-sided cardiac tumors and the value of multimodality imaging plus tissue sampling in atypical presentations.
Shah S, Gill JS, Gill J et al. · BMJ case reports · (2026) · View on PubMed ↗
Imaging of Myocardial Carcinoid Metastasis.
This JACC Case Reports article described two patients with metastatic neuroendocrine tumors (NETs) presenting with isolated myocardial metastases without valvular involvement. In both cases, Gallium-68 DOTATATE PET/CT identified cardiac involvement and cardiac magnetic resonance (CMR) further characterized myocardial lesions, whereas transthoracic echocardiography had limited sensitivity for detecting myocardial metastases. The report highlights the clinical significance of multimodality imaging—especially CMR following DOTATATE PET/CT—for recognizing otherwise under-diagnosed cardiac NET metastasis.
Ranganath S, Ynalvez L, Ryoo Ali HJ et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac tumour in paediatrics: the role of multimodal imaging and therapeutic catheterisation.
This case report in pediatric cardiology described a 14-year-old boy initially misdiagnosed with asymmetric septal hypertrophic cardiomyopathy after a murmur, later found to have a highly vascular interventricular septal mass. Multimodal imaging including echocardiography and cardiac magnetic resonance (CMR) characterized the lesion (including hyperintensity on HASTE/T1/T2 and high extracellular volume), and therapeutic catheterization was part of the management pathway. The case is significant because it demonstrates how multimodal imaging can redirect diagnosis and guide intervention for pediatric cardiac tumors that mimic cardiomyopathy.
Trujeque L, Hernandez K, Tavera A · Cardiology in the young · (2026) · View on PubMed ↗ · Free PDF ↗
Nuclear Imaging (FDG PET/Pyrophosphate) in Cardiac Disease
Apical Hypertrophic Cardiomyopathy in ATTR Val142Ile Carrier: When Genes and Phenotype Diverge.
This JACC Case Reports article described a 61-year-old African-American man with longstanding apical hypertrophic cardiomyopathy (ApHCM) who was found to carry the pathogenic transthyretin (TTR) variant Val142Ile (V142Ile). Despite genotype positivity, technetium-99m pyrophosphate scintigraphy (H/CL 1.01, visual grade 0) excluded transthyretin cardiac amyloidosis cardiomyopathy (ATTR-CM), while cardiac MRI confirmed apical-predominant hypertrophy with patchy late gadolinium enhancement. The case demonstrates gene–phenotype divergence and the importance of imaging confirmation to avoid misclassifying phenocopies as ATTR-CM in TTR mutation carriers.
Khayat O, Moumneh MB, Salman O et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
FDG PET for cardiac sarcoidosis: Protocol optimization, quantification, pitfalls, and multimodality imaging integration.
This narrative review synthesized evidence on FDG PET in cardiac sarcoidosis (CS), focusing on protocol optimization, quantification methods, common pitfalls, and how PET integrates with echocardiography and cardiac MRI (CMR) in multimodality diagnostic frameworks. The key finding was that standardized dietary preparation and careful quantification/interpretation of FDG uptake are critical to improving diagnostic performance and reducing false positives, especially when integrated with CMR and clinical context. This provides practical guidance for nuclear cardiology workflows to improve CS diagnosis and management.
Wopperer SB, Kronzer E, Ivare J et al. · Seminars in nuclear medicine · (2026) · View on PubMed ↗
AI/Automation for Cardiac Imaging & Diagnostics
Investigation of Concordance between Artificial Intelligence and Manual Measurements of the Cardiac Parameters in Cardiac Magnetic Resonance Imaging.
This prospective external validation study assessed concordance between a commercially available artificial intelligence (AI) system and manual measurements for cardiac magnetic resonance (CMR) parameters in 100 healthy Chinese volunteers. The key finding was that AI-derived biventricular metrics and per-segment left ventricular wall thickness (LVWT) measurements showed strong agreement with manual measurements in an independent clinical setting. This supports broader clinical deployment of AI-assisted CMR quantification for standardized cardiac parameter measurement.
Tang R, Xu Z, Huang Z et al. · Journal of imaging informatics in medicine · (2026) · View on PubMed ↗
Contrastive language image pretraining for a cardiac magnetic resonance image embedding with zero-shot capabilities.
This study developed and evaluated CMR-CLIP, a contrastive language image pretraining model that learns image-report embeddings from cardiovascular magnetic resonance (CMR) studies treated as video-like inputs. The key finding was that CMR-CLIP achieved zero-shot capabilities for CMR representation tasks without requiring precise image-text pairing, leveraging 11,028 single-center studies. This advances foundation-model approaches for CMR by enabling scalable, report-aligned embeddings that may reduce labeling burden in cardiovascular imaging.
Nakashima M, Qiu J, Huang P et al. · Nature communications · (2026) · View on PubMed ↗ · Free PDF ↗
Fourier-Net+: Band-Limited Spatial Representation for Efficient Medical Image Registration.
This paper developed Fourier-Net+ for unsupervised medical image registration, targeting high-resolution volumetric data where full-resolution dense displacement-field prediction is computationally expensive. Fourier-Net+ uses deterministic Fourier-domain band-limiting for efficient down/up-sampling and a parameter-free, model-driven decoder to learn a low-dimensional, band-limited displacement representation. The method is significant because it can reduce registration time and resource use while maintaining broad modality compatibility for deformable image alignment.
Jia X, Thorley A, Gomez A et al. · IEEE transactions on neural networks and learning systems · (2026) · View on PubMed ↗
Cardiac Imaging in Systemic/Autoimmune Diseases
Inaugural cardiac involvement in Goodpasture syndrome: a case report.
This case report described inaugural cardiac involvement in a 44-year-old Tunisian woman with Goodpasture syndrome presenting initially with NSTEMI-like symptoms and elevated troponin. Cardiac MRI demonstrated transmural myocardial necrosis, and subsequent massive hemoptysis, acute respiratory distress syndrome, and acute kidney injury led to identification of anti-glomerular basement membrane (anti-GBM) disease. The report highlights that early cardiac MRI findings can reveal rare cardiac manifestations of Goodpasture syndrome and support timely diagnosis of anti-GBM vasculitis.
Lassoued T, Ferjani S, Abbassi M et al. · Journal of medical case reports · (2026) · View on PubMed ↗
Discordant Cardiomyopathy Phenotypes in Siblings With Homozygous FKRP c.1100T>C.
This JACC Case Reports article describes two South African Afrikaner siblings homozygous for the founder FKRP variant c.1100T>C (p.Ile367Thr), both with discordant cardiomyopathy phenotypes. The brother developed progressive cardiomyopathy with later dilatation and extensive late gadolinium enhancement fibrosis over years, illustrating variable cardiac expression despite the same genotype. The case underscores that additional modifiers beyond FKRP genotype can drive divergent cardiac phenotypes in limb-girdle muscular dystrophy R9.
Mahon N, Coad S, Kiamanesh O · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Serum vs. tissue cytokine dysregulation in SLE-associated myocarditis: a hypothesis from an African cohort perspective.
This hypothesis-driven study compared serum cytokine dysregulation with cardiac tissue inflammatory cytokine profiles in an African mixed-ancestry cohort of systemic lupus erythematosus (SLE) patients, including SLE without myocarditis and SLE-associated myocarditis (LM), with cardiac MRI (CMR) and standard-of-care biomarkers. The key finding was that cardiac tissue cytokine patterns in SLE myocarditis correlated with SOC measures (serum biomarkers and CMR), highlighting discordance between blood and tissue inflammation. This provides mechanistic support for tissue-targeted understanding of lupus myocarditis and suggests that CMR plus biomarker assessment may better reflect cardiac involvement than serum alone.
Ollewagen T, Toit RD, Karamchand S et al. · Molecular medicine (Cambridge, Mass.) · (2026) · View on PubMed ↗ · Free PDF ↗
Current state of knowledge on the epidemiology, aetiology, diagnosis, and management of heart involvement in eosinophilia. A Clinical Consensus Statement of the ESC Working Group on Myocardial & Pericardial Diseases.
This European Society of Cardiology (ESC) Working Group clinical consensus statement reviewed the epidemiology, causes, diagnosis, and management of heart involvement in eosinophilia (eosinophilic heart disease). The key finding was that cardiac involvement is frequently missed early and may occur even without peripheral eosinophilia, making organ/tissue biopsy essential for correct diagnosis in selected patients. This emphasizes earlier recognition and guideline-informed management to reduce cardiac morbidity and mortality in eosinophilia-associated disease.
Kuchynka P, Brucato A, Tschöpe C et al. · European journal of heart failure · (2026) · View on PubMed ↗
Elevated sST2 associates with cardiac involvement and declines after treatment in newly diagnosed patients with idiopathic inflammatory myopathies.
This longitudinal cohort study measured soluble suppression of tumorigenicity 2 (sST2) in newly diagnosed and established idiopathic inflammatory myopathies (IIM) patients (34 newly diagnosed, 109 established) and compared them with age- and gender-matched healthy controls and rheumatoid arthritis (RA) patients. Elevated sST2 was associated with cardiac involvement (CI) and declined after treatment over a 2-year follow-up period. These results suggest sST2 could serve as a biomarker for cardiac inflammation/remodeling activity and treatment response in IIM.
Hanna B, Lundberg IE, Ekwall AH et al. · Arthritis research & therapy · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac Electrophysiology & Arrhythmia Risk (Imaging/Mechanisms)
Targeting Arrhythmogenic Late Sodium Current by FHF1A-Derivative FixR in Heart Failure Cardiomyocytes.
The study investigated whether a FixR (FHF inhibiting x region) targeting fibroblast growth factor homologous factors 1–4 (FHF1–4) modulates late sodium current (INa,L) in human heart failure with reduced ejection fraction (HFrEF) and related translational animal models. Reverse-transcriptase quantitative PCR characterized cardiac sodium channel and FHF splice isoforms, and FixR testing showed effects on cardiomyocyte INa,L relevant to arrhythmogenic mechanisms in HF. Targeting the FHF–INa,L axis may represent a gene-pathway-directed strategy to reduce proarrhythmia risk in HFrEF.
Hegyi B, Angsutararux P, Chakouri N et al. · Circulation research · (2026) · View on PubMed ↗
Catheter ablation of epicardial premature ventricular complexes in patients with and without cardiac scar.
This retrospective study evaluated catheter ablation outcomes for left ventricular epicardial premature ventricular complexes (PVCs) in patients with and without myocardial scar, using late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) to define scar presence. Acute and long-term procedural outcomes were compared between epicardial PVC patients with versus without cardiac scar. The results are clinically relevant because they clarify how myocardial scar burden may influence the success and durability of epicardial PVC ablation strategies.
Jiwani S, Arps K, Shah M et al. · Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · (2026) · View on PubMed ↗ · Free PDF ↗
Hemodynamic/Physiology Imaging & Exercise Response
Smaller Right Ventricle Results in Poorer Exercise Performance in Young Patients With Repaired Tetralogy of Fallot.
This study examined young patients with repaired tetralogy of Fallot (rTOF) to determine whether right ventricular (RV) size relates to exercise performance, using cardiopulmonary exercise testing (CPET) and cardiac magnetic resonance imaging (CMR) in 37 patients (mean age 17±5 years). The key finding was that smaller right ventricle size was associated with poorer exercise performance, with oxygen pulse (V̇O2/heart rate) used as a surrogate for stroke volume and correlations assessed against CMR measures. Clinically, RV size metrics from CMR may help refine risk stratification for exercise intolerance and guide timing of pulmonary valve replacement decisions.
Mhanna C, Kourpas K, Tsuda T · Circulation journal : official journal of the Japanese Circulation Society · (2026) · View on PubMed ↗ · Free PDF ↗
Dynamic right ventricular and atrial volume responses to exercise in endurance-trained and untrained healthy individuals.
This study compared dynamic right ventricular (RV) and atrial (left and right) volume responses to exercise in endurance-trained versus untrained healthy individuals using exercise real-time cardiac magnetic resonance (CMR) with respiratory control. It found that the four-chamber heart’s volume changes during exercise differed between endurance-trained and untrained groups, extending prior observations of enhanced left ventricular function in trained individuals. The significance is mechanistic insight into how training alters cardiopulmonary hemodynamics, informing interpretation of exercise CMR in healthy physiology.
Östenson B, Ostenfeld E, Edlund J et al. · PloS one · (2026) · View on PubMed ↗ · Free PDF ↗
Clinical Prediction Models & Noninvasive Risk Stratification
Prediction of Left Ventricular Systolic Dysfunction from ICU Electrocardiograms Using Vision Transformer Embeddings and Multimodal Features.
This retrospective ICU study developed a multimodal model to predict reduced left ventricular ejection fraction (LVEF ≤40%) directly from 12-lead electrocardiograms by combining Vision Transformer (ViT) deep embeddings pretrained on CMR data with conventional quantitative ECG features. Classifiers including Random Forest, XGBoost, and a focal-loss shallow multilayer perceptron (MLP) were trained on ~900 ICU admissions from a single tertiary center. The approach could enable earlier identification of LV systolic dysfunction in critically ill patients when echocardiography/CMR is delayed or unavailable.
Lenkowicz J, di Giorgi N · Studies in health technology and informatics · (2026) · View on PubMed ↗ · Free PDF ↗
Relationship between hemodynamic forces based on CMR and major adverse cardiac events in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors.
This prospective study investigated whether cardiovascular magnetic resonance (CMR) hemodynamic force parameters relate to major adverse cardiac events (MACE) in cancer patients receiving anti-PD-1/PD-L1 immune checkpoint inhibitors. It found that patients underwent CMR about 12 weeks after starting immunotherapy (with normal baseline echocardiograms), enabling analysis of how CMR-derived hemodynamic forces predict subsequent MACE. The clinical significance is potential risk stratification for immunotherapy-associated cardiotoxicity using noninvasive CMR metrics.
Gao D, Wang Y, Shi Y et al. · BMC medical imaging · (2026) · View on PubMed ↗ · Free PDF ↗
Comparison of Left Ventricular Ejection Fraction and Disease Classification by Cardiac Magnetic Resonance and Echocardiography.
This retrospective study compared left ventricular ejection fraction (LVEF) measurements obtained by cardiac magnetic resonance (CMR) versus transthoracic echocardiography (TTE) in 1213 patients undergoing both tests within 1 week, and assessed determinants of discordant European Society of Cardiology heart failure classification using LVEF thresholds (50% and 35%). LVEF values and resulting clinical classification differed between CMR and TTE, with imaging characteristics identified as predictors of classification discordance via logistic regression. The findings support more careful interpretation of LVEF cutoffs when switching between CMR and echocardiography for heart failure phenotyping and treatment decisions.
Le Y, An J, Liang L et al. · The American journal of cardiology · (2026) · View on PubMed ↗
Non-cardiac/Health Systems & Public Health
An international randomised controlled trial of a novel antimicrobial dressing for peripheral intravenous catheters (ProP trial).
The ProP trial studied the feasibility and preliminary clinical outcomes of chlorhexidine gluconate (CHG)-impregnated dressings for peripheral intravenous catheters (PIVCs) in a multicentre adaptive randomized controlled trial in Australia. The key finding reported in the abstract is the trial’s assessment of feasibility and early outcomes for CHG-impregnated PIVC dressings compared with standard care, addressing a gap where CHG evidence is established for central lines but not PIVCs. If effective, this strategy could reduce phlebitis and infection-related antimicrobial use in routine hospital PIVC care.
Drugeon B, Ball DL, Kleidon TM et al. · Antimicrobial resistance and infection control · (2026) · View on PubMed ↗
Analysis of OSCE-based clinical competency assessment among critical care medicine residents in Zhejiang Province, China: a multicenter retrospective cohort study.
This multicentre retrospective cohort study analyzed Objective Structured Clinical Examination (OSCE) performance among 175 critical care medicine residents across seven training bases in Zhejiang Province, China (2023–2025). The key finding was an assessment of OSCE score patterns by training base to identify educational gaps and inform optimization of residency training. The results support using station-based OSCE analytics to target curriculum improvements in critical care education.
Chen C, Mao W, Cai K et al. · BMC medical education · (2026) · View on PubMed ↗ · Free PDF ↗
Two decades of pulmonary vascular disease and ischemic heart disease mortality in the united states: A longitudinal analysis using CDC WONDER (1999-2020).
This retrospective longitudinal analysis used the CDC WONDER database to study pulmonary vascular disease (PVD) and ischemic heart disease (IHD) mortality trends in U.S. adults aged ≥45 years from 1999–2020. Across the combined PVD+IHD dataset (184,780 deaths), overall age-adjusted mortality rates increased from 6.9 to 8.9 per 100,000 over the study period, with mortality quantified using joinpoint regression (annual percent change) stratified by demographic and geographic factors. These findings highlight changing cardiovascular mortality burdens and potential demographic/geographic disparities that can inform targeted public health and clinical risk-reduction strategies.
Nawaz A, Hafeezullah F, Siddiqui ZA et al. · Journal of thrombosis and thrombolysis · (2026) · View on PubMed ↗
Sustained and discontinued operational changes to ethics committees in the post-pandemic era: a qualitative study in Kenya.
This qualitative study explored ethics committee (EC) operational changes retained or discontinued after the COVID-19 pandemic in Kenya, focusing on how ECs adapted rapid review processes during public health emergencies. The study assessed which pandemic-era EC workflow adjustments were sustained versus dropped in the post-pandemic period. Understanding these changes is significant for strengthening resilient, ethically robust research oversight during future public health emergencies.
Kebenei E, Cheruiyot D, Bukusi EA et al. · BMC medical ethics · (2026) · View on PubMed ↗ · Free PDF ↗
Rotator Cuff Repair With Bone Marrow Stimulation Versus Rotator Cuff Repair With Patch Augmentation: A Systematic Review.
This systematic review compared rotator cuff repair (RCR) augmented with bone marrow stimulation (BMS) versus RCR augmented with patch augmentation (PA), synthesizing Level 1–2 studies identified via PubMed, Cochrane Library, and Embase. The review aimed to determine differences in clinical efficacy and retear rates between the two adjunct techniques. The findings are important for evidence-based selection of biologic/construct-support strategies to improve healing and reduce retear after RCR.
Lim JJ, McCarty C, Belk JW et al. · Orthopaedic journal of sports medicine · (2026) · View on PubMed ↗
Measurement of quality of stroke care with national electronic health records: a prospective cohort study during and after the COVID-19 pandemic.
This prospective England-wide cohort study used linked electronic health records (EHRs) from the Sentinel Stroke National Audit Programme (SSNAP), primary/secondary care, dispensed medications, and mortality data to evaluate stroke care quality before and after the COVID-19 pandemic in 425,675 adults. The study assessed metrics including stroke incidence, secondary prevention medication dispensing, and “home-time” (disability-time spent at home) as a proxy outcome not routinely captured. By validating the use of national linked EHRs for stroke quality measurement, the work provides a scalable approach to monitor and improve post-pandemic stroke care delivery.
Farrell J, Nolan J, Lambert R et al. · BMJ open · (2026) · View on PubMed ↗ · Free PDF ↗
Trends and Projections for Aortic Stenosis and Hypertension-Related Mortality Among Older Adults in the United States: A Retrospective Population-Based Analysis.
This retrospective population-based analysis used CDC WONDER multiple cause-of-death data to examine trends, demographic-geographic disparities, and projections for mortality related to comorbid aortic stenosis (AS) and hypertension (HTN) among older adults in the United States from 1999–2020. The study quantified changes in crude and age-adjusted mortality rates and used joinpoint regression plus ARIMA modeling to project mortality through 2030. The results are important for public health planning by clarifying how combined AS/HTN mortality evolves over time and where disparities may widen.
Bhatti MI, Safiullah M, Farhan K et al. · High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · (2026) · View on PubMed ↗
Generated automatically on May 26, 2026. Covers PubMed articles published May 19, 2026 – May 26, 2026. Summaries are AI-generated; always consult the original publication for clinical or research decisions.