What's New in Cardiac MRI? — June 23, 2026
AI-summarised digest of 61 PubMed articles on Cardiac MRI published in the last 7 days.
Jump to category
What’s New in Cardiac MRI?
June 23, 2026 · 61 articles · 15 research themes · covering June 16, 2026 – June 23, 2026
Overview
This week’s digest is dominated by advances in cardiovascular magnetic resonance (CMR) as both a mechanistic biomarker platform and a clinical decision tool. Multiple studies link CMR-derived remodeling—such as fibrosis, strain, synchrony, and atrial functional measures—to downstream outcomes ranging from heart failure progression and major cardiovascular events to cognitive decline after cardiac allograft vasculopathy. In parallel, several works emphasize the value of integrated, multimodal CMR phenotyping (e.g., combining perfusion metrics with diffuse fibrosis) and of quantitative flow/pressure approaches (including 4D flow–based measures) for improved risk stratification beyond conventional imaging endpoints.
A second major theme is the rapid maturation of AI across the cardiac imaging workflow: from robust cross-scanner segmentation and motion tracking for strain analysis, to report structuring that reduces ambiguity in cine CMR interpretation, to ECG-based AI screening for hypertrophic cardiomyopathy and narrative reviews mapping where AI is currently most effective (often as enrichment rather than standalone diagnosis). These efforts collectively aim to make advanced imaging more scalable, reproducible, and clinically actionable.
Finally, the digest highlights the expanding cardio-oncology and inflammatory myocarditis/pericardial landscape. Case reports and mechanistic reviews underscore that modern cancer immunotherapies and targeted agents can produce myocarditis or pericardial syndromes that mimic acute coronary syndromes, and that early CMR phenotyping can be pivotal for diagnosis and management. Complementing this, consensus guidance and athlete-focused imaging studies reinforce standardized, multimodality strategies to distinguish physiological adaptation from pathology—an approach that increasingly mirrors the broader push toward precision phenotyping across patient populations.
Cardio-Oncology: Cancer therapy–related cardiac toxicity
A rare case of fulminant talquetamab-induced myocarditis presenting as a STEMI mimicker.
This case report studied a 69-year-old man with relapsed/refractory multiple myeloma treated with talquetamab, a CD3/GPRC5D bispecific T-cell engager, who developed fulminant myocarditis presenting as a STEMI mimicker. The key finding was that myocarditis occurred after talquetamab initiation and was steroid-refractory, leading to a presentation that mimicked acute myocardial infarction. Clinically, it underscores the need for early cardiac evaluation and myocarditis consideration in patients receiving talquetamab and other novel T-cell–engaging immunotherapies.
Kim EJ, Saravia SD, Sahni G · Cardio-oncology (London, England) · (2026) · View on PubMed ↗ · Free PDF ↗
Myopericarditis After Combined Idarubicin and Quizartinib in FLT3-ITD-Positive AML.
This JACC Case Reports report described a 64-year-old man with acute myelogenous leukemia who developed myopericarditis after sequential cytarabine and idarubicin (anthracycline exposure) followed by quizartinib, a FLT3 inhibitor. Cardiac magnetic resonance showed late gadolinium enhancement consistent with myopericarditis in the setting of troponin elevation and diffuse ST-segment elevation. The case raises clinical concern that FLT3 inhibition with quizartinib may exacerbate or unmask cardiotoxic inflammatory injury in patients already exposed to anthracyclines.
Spahr ZR, Vasquez MA, Tangella A et al. · JACC. Case reports · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗
Fluoropyrimidine Cardiotoxicity With Overlapping Vasospastic and Pericardial Features: A Diagnostic Challenge.
This case report described a 57-year-old man with HER2-positive gastric cancer who developed fluoropyrimidine cardiotoxicity during 5-fluorouracil (5-FU) infusion as part of FOLFOX-6M plus trastuzumab. The presentation combined features of coronary vasospasm (including marked QTc prolongation and evolving ST-segment elevation) with pericardial/inflammatory characteristics, creating a diagnostic challenge despite initially negative biomarkers and normal echocardiography and coronary CT angiography. Clinically, it underscores the need for rapid recognition and careful differentiation of overlapping vasospastic and pericardial syndromes during fluoropyrimidine therapy.
Viñas-Mendieta AE, Valencia-Hernandez HA, Ruiz-Mori E et al. · JACC. Case reports · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗
Cardio-Oncology: Cancer risk prediction from cardiovascular imaging
Association of Subclinical Cardiac Remodeling With Incident Cancer in the MESA Cohort.
This study examined whether cardiac magnetic resonance imaging (CMR) measures of subclinical cardiac remodeling are associated with incident cancer in participants of the Multi-Ethnic Study of Atherosclerosis (MESA). Using multivariable Cox proportional hazards models, the authors evaluated the relationship between each CMR-derived remodeling metric and time to cancer diagnosis across an all-inclusive cancer endpoint and cancer subtypes (including prostate and breast). If CMR-detected subclinical remodeling predicts future cancer risk, it could support shared pathophysiology between cardiovascular remodeling and carcinogenesis and improve risk stratification beyond traditional factors.
Cai X, White Q, Juarez J et al. · Journal of the American Heart Association · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac MRI/CT AI for Imaging, Segmentation, and Reporting
Parameter-efficient adaptation of foundational models for automated myocardial strain analysis.
The research investigated parameter-efficient adaptation of foundational segmentation and motion-tracking models for automated myocardial strain analysis across cardiac imaging domains, focusing on cross-scanner generalization. The key finding was that CardiacSAM (Segment Anything Model fine-tuned with Low-Rank Adaptation) combined with uniGradICON for myocardial motion estimation enabled robust strain estimation with minimal adaptation data for deployment to new institutions. Scientifically, this provides a practical pathway to reduce dataset dependence and improve reliability of automated myocardial strain quantification in real-world clinical imaging pipelines.
Bernardo A, Mato G, Calandrelli M et al. · Biomedical physics & engineering express · (2026) · View on PubMed ↗ · Free PDF ↗
CineScribe: LLM-based detection and mitigation of ambiguity in cine cardiac magnetic resonance reports.
This study developed CineScribe, an LLM-based system trained on expert-annotated cine cardiac MRI (cineCMR) reports to detect and mitigate ambiguity by converting free-text into structured regional wall-motion abnormality (RWMA) representations. The key finding was that CineScribe achieved strong performance on report structuring (macro-F1 0.92, 95% CI 0.89–0.94), enabling standardized generation from validated diagnostic findings. Scientifically and clinically, it supports more consistent cineCMR interpretation and reduces miscommunication risk from imprecise narrative reporting.
Villanueva Benito G, Descalzo ML, Pujadas S et al. · Computers in biology and medicine · (2026) · View on PubMed ↗ · Free PDF ↗
Artificial Intelligence for the Detection of Hypertrophic Cardiomyopathy From Standard Electrocardiogram.
This diagnostic study evaluated an artificial intelligence algorithm (Viz HCM, Viz.ai) for hypertrophic cardiomyopathy (HCM) detection using 12-lead electrocardiograms (ECGs) in a cohort of 150 patients with suspected HCM who had analyzable ECGs and were confirmed by cardiac MRI (cMRI) and physician record review, plus 83 controls without cardiomyopathy. The key finding was that the AI algorithm could classify ECGs as HCM-positive versus negative with clinically useful performance and that specific predictors contributed to correct classification. Clinically, this supports ECG-based AI as an earlier screening/enrichment tool to reduce delayed HCM diagnosis and prompt confirmatory imaging.
Park J, Kermanshahchi J, Love CJ et al. · JACC. Advances · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac MRI Hemodynamics & Flow Quantification
Prognostic Value of Coronary Sinus Flow and Aortic Pressure Gradient Quantified by 4D Flow CMR in AMI.
This retrospective study investigated prognostic value in 103 acute myocardial infarction (AMI) patients who underwent CMR before percutaneous coronary intervention (PCI), using 4D flow CMR-derived coronary sinus flow (CS flow) and aortic pressure gradients. It found that CS flow (normalized to left ventricular mass) and peak pressure gradients across the aortic valve were associated with a composite endpoint including all-cause death, unplanned revascularization, recurrent MI, heart-failure rehospitalization, and stroke. The clinical significance is that 4D flow CMR metrics may provide additional risk stratification in AMI beyond standard imaging and clinical variables.
Li Y, Wang S, Li G et al. · Academic radiology · (2026) · View on PubMed ↗
Analysis of cardiac dynamic global function.
This work proposed a systematic, AI-assisted approach to analyze cardiac dynamic global function from imaging by moving beyond conventional end-diastole/end-systole volume and ejection fraction metrics that are limited by time-consuming segmentation. The key finding was the feasibility of generating standardized measures of dynamic changes in cardiac volumes over the cardiac cycle using AI-enabled segmentation and a structured analysis pipeline. Scientifically, it addresses the lack of standardized methods for dynamic global function assessment and could enable more sensitive detection of disease-related functional impairment.
Axel L, Kanski M, Jhaveri A et al. · JRSM cardiovascular disease · (2026) · View on PubMed ↗ · Free PDF ↗
Agreement between ventricular stroke volumes and great vessel flow using cine and phase-contrast MRI in healthy subjects.
This study in 15 healthy volunteers compared left ventricular stroke volume (LV-SV) and right ventricular stroke volume (RV-SV) derived from cine CMR with great vessel forward flow measured by phase-contrast MRI in the ascending aorta (Ao) and pulmonary artery (PA). The key finding was imperfect agreement between ventricular stroke volumes and corresponding great vessel flows, with Bland–Altman analysis showing negative additive bias for RV-PA, RV-Ao, and RV-LV parameter pairs. Scientifically and clinically, it highlights limitations of indirect regurgitation quantification approaches that assume equivalence among these CMR-derived measures.
Kawaguchi A, Kawaguchi W, Hayashi M et al. · Radiological physics and technology · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac MRI Biomarkers of Myocardial Remodeling (Fibrosis/Strain/Synchrony)
Pre-heart failure in early chronic kidney disease: clinical epidemiology and treatment.
This review studied the concept of “pre-heart failure” in early chronic kidney disease (CKD), focusing on epidemiology and treatment implications in CKD stages G1–G3, particularly with albuminuria (KDIGO A2–A3). It found that even mild eGFR reductions in this population correlate with subclinical cardiac abnormalities such as left ventricular hypertrophy, concentric remodelling, left ventricular diastolic dysfunction, heart failure with preserved ejection fraction (HFpEF), and arrhythmias. The clinical significance is that CKD-associated cardiac dysfunction may represent an earlier, treatable stage before overt heart failure develops.
Zoccali C, De Caterina R, Tuttle KR et al. · European heart journal · (2026) · View on PubMed ↗
Heart involvements in systemic sclerosis beyond pulmonary hypertension: From conduction, rhythm and function defects to coronary artery disease.
This narrative review studied cardiac involvement in systemic sclerosis (SSc) beyond pulmonary hypertension, covering conduction, rhythm, functional defects, and coronary artery disease. It found that cardiac disease is frequently underestimated: clinically manifest cardiac involvement occurs in roughly 15–35% of patients, while subclinical dysfunction is detected in about 70% with advanced screening, including myocardial fibrosis, coronary microvascular dysfunction, arrhythmias, conduction disorders, and pericardial/valvular disease. The clinical significance is that comprehensive cardiac screening in SSc may reduce morbidity and mortality by identifying early, non–pulmonary-hypertension-related cardiac pathology.
Barile R, Rotondo C, Giancaspro G et al. · La Revue de medecine interne · (2026) · View on PubMed ↗
Microvascular dysfunction and neurovascular signalling impairment in diabetic silent myocardial ischemia.
This review article studied the mechanisms underlying diabetic silent myocardial ischemia (DSMI), focusing on coronary microvascular dysfunction and neurovascular signaling impairment in the setting of chronic hyperglycemia. The key finding was that oxidative stress, advanced glycation end-product (AGE) accumulation, and mitochondrial dysfunction reduce nitric oxide (NO) bioavailability and capillary integrity while diabetic peripheral/autonomic neuropathy blunts nociceptive signaling. Scientifically, it links two converging pathological axes to explain DSMI’s symptom-free presentation and highlights targets for future therapeutic intervention.
Rajasekaran HK · Microvascular research · (2026) · View on PubMed ↗
Brain Cortex Thinning in Cardiac Allograft Vasculopathy - Associations With Myocardial Fibrosis and Cognitive Impairment.
This clinical imaging study examined brain cortex thinning in patients after heart transplantation, comparing those with cardiac allograft vasculopathy (CAV) versus those without CAV and versus healthy controls using brain MRI and cardiac MRI. The key finding was that the CAV group showed significant cortical thinning in specific regions (e.g., bilateral superior frontal gyrus, left angular gyrus, left supramarginal gyrus) and that these changes were associated with myocardial fibrosis and cognitive impairment. Clinically, it suggests a neuroanatomic biomarker pathway linking CAV-related cardiac injury to cognitive decline.
Qin Q, Zhu D, Zheng N et al. · Circulation journal : official journal of the Japanese Circulation Society · (2026) · View on PubMed ↗ · Free PDF ↗
Primary heart involvement assessed by cardiac magnetic resonance is associated with capillaroscopy abnormalities in systemic sclerosis.
This cross-sectional exploratory study evaluated primary heart involvement in 40 patients with systemic sclerosis (SSc) using cardiac magnetic resonance (CMR) after a cold-stress protocol and compared it with peripheral vasculopathy assessed by nailfold capillaroscopy. The study found that CMR-defined SSc heart involvement was associated with capillaroscopy abnormalities, linking microvascular dysfunction in the periphery to cardiac tissue/functional changes detected by CMR. These findings support CMR as a sensitive tool for identifying clinically relevant cardiac involvement in SSc and suggest that peripheral microangiopathy may mirror cardiac microvascular pathology.
Martins L, Uellendahl M, Ferreira G et al. · Advances in rheumatology (London, England) · (2026) · View on PubMed ↗ · Free PDF ↗
Myocardial fibrosis is associated with worse left ventricular strain and synchrony assessed by novel CMR imaging in the general population: data from the Akershus Cardiac examination 1950 study.
This population-based CMR study analyzed 200 elderly participants without known coronary artery disease (Akershus Cardiac Examination 1950) to test how myocardial fibrosis relates to left ventricular deformation and mechanical synchrony. Diffuse fibrosis quantified by septal extracellular volume (ECV) and focal fibrosis quantified by late gadolinium enhancement (LGE) were associated with worse LV strain and altered mechanical dispersion/synchrony measured with CMR feature tracking (CMR-FT) and fast strain-encoded MR (fSENC). These findings support the use of advanced CMR fibrosis metrics to detect subclinical myocardial remodeling that may precede overt cardiovascular disease.
Wimalanathan T, Sulkowska J, Melles AW et al. · The international journal of cardiovascular imaging · (2026) · View on PubMed ↗ · Free PDF ↗
Pectus Excavatum-Induced Preload Insufficiency Presenting as Long-Standing Sinus Tachycardia.
This JACC Case Reports report studied a 65-year-old woman with long-standing sinus tachycardia and refractory symptoms despite high-dose beta-blockade, investigating the hemodynamic impact of severe pectus excavatum. Right heart catheterization showed markedly low filling pressures (mean right atrial pressure 1 mm Hg) with preserved cardiac output, and cardiovascular magnetic resonance demonstrated severe anterior cardiac compression (Haller index 8.1). The case highlights that pectus excavatum can cause preload insufficiency presenting as persistent sinus tachycardia, supporting CMR and invasive hemodynamics to identify a reversible mechanical cause.
Alkhatib R, Zghyer F, Hatab T et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Giant Postischemic Left Ventricular Aneurysm Without Q Waves: Multimodality Imaging-Guided Surgery.
This JACC Case Reports report described a 55-year-old woman with inferolateral myocardial infarction who developed a giant postischemic left ventricular aneurysm without pathological Q waves. Multimodality imaging demonstrated progressive left ventricular remodeling with aneurysmal evolution and mural thrombus despite misleading electrocardiographic findings, guiding multimodality imaging-guided surgery. The case emphasizes that absence of Q waves does not exclude aneurysm formation and that imaging-based surveillance can be critical for timely surgical management.
Gaido L, Attisani M, Scalini F et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Rapid Onset of Iron Overload Cardiomyopathy in Cirrhosis.
This case report described two patients with cirrhosis who developed rapid-onset iron overload cardiomyopathy (IOC) without hereditary hemochromatosis or transfusion-dependent anemia. Both patients presented with new or worsening cardiomyopathy with markedly reduced left ventricular ejection fraction over a short interval. The report highlights that iron accumulation in cirrhosis can precipitate IOC, supporting earlier cardiac evaluation and iron assessment in at-risk cirrhotic patients.
Nouraee CM, Swain WH, Harmon DM et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Metabolic and Redox Pathway Dysregulation in HIV-Associated Coronary Endothelial Dysfunction.
In virally suppressed people with HIV (PWH) on antiretroviral therapy, this prospective observational study integrated in vivo stress cardiovascular magnetic resonance (CMR) with high-throughput serum proteomics to identify circulating protein signatures linked to coronary endothelial dysfunction. The key finding was that coronary endothelial dysfunction in treated PWH corresponded to proteomic signatures indicating metabolic and redox pathway dysregulation. This is significant because it provides mechanistic biomarkers that may explain persistent cardiovascular risk in virally suppressed HIV and could guide targeted therapeutic strategies.
Keole KS, Bukhari S, Minhas A et al. · American journal of physiology. Heart and circulatory physiology · (2026) · View on PubMed ↗
Cardiac Imaging in Cardiomyopathies & Genetic/Phenotypic Risk
Right Side Accessory Pathway Mediated Cardiomyopathy Treated with Amiodarone: First Adult Case Report.
This first adult case report studied a 44-year-old man with Wolff-Parkinson-White syndrome and a right-sided accessory pathway mediated cardiomyopathy to test whether amiodarone could achieve complete pharmacologic reversal. The key finding was that amiodarone treatment led to reversal of the preexcitation pattern and improvement of the cardiomyopathy without proceeding directly to catheter ablation. Clinically, this suggests a potential noninvasive option for stabilizing adult accessory-pathway–related cardiomyopathy when ablation is not immediately feasible.
Costa A, Laxina I, Hakim F et al. · American journal of therapeutics · (2026) · View on PubMed ↗ · Free PDF ↗
Spindle Cell Cardiac Lipoma in an Adolescent: A Case Report and Systematic Review of Cases.
This case report and systematic review studied spindle cell cardiac lipoma in a 13-year-old adolescent presenting with a cardiac murmur and intracardiac masses. The key finding was that imaging (echocardiography and cardiac MRI) demonstrated a lobulated mass involving the aortic valve with extension into the left ventricular outflow tract, and the case highlights diagnostic uncertainty that required surgical management. The significance lies in documenting an exceptionally rare pediatric cardiac tumor and summarizing clinical features to improve recognition and diagnostic strategy.
Soh SL, Wee IJY, Murray Binti Jeffery Murray RL et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Left ventricular non-compaction in heart failure: contemporary perspective on diagnostic challenges and treatment opportunities.
This narrative review synthesized evidence on left ventricular non-compaction (LVNC) versus left ventricular hypertrabeculation (LVHT) in heart failure, focusing on diagnostic challenges, imaging criteria, pathophysiology, and genetic background. The key message is that distinguishing adaptive trabeculation from true LVNC is critical because misclassification can lead to inappropriate interventions or missed identification of high-risk patients. Scientifically and clinically, the review highlights how contemporary imaging and genetics should be integrated to improve diagnosis and management of LVNC/LVHT phenotypes.
Geavlete O, Tschöpe C, Angermann CE et al. · Heart failure reviews · (2026) · View on PubMed ↗
Occult Idiopathic Ventricular Fibrillation After Preoperative Cardiovascular Evaluation.
This case report studied a 50-year-old man who experienced out-of-hospital cardiac arrest about 1 hour after preoperative cardiovascular clearance for elective surgery, with no prior symptoms or known structural heart disease. Despite extensive evaluation including coronary angiography, cardiac magnetic resonance, electrophysiological study, and genetic testing, no cause of idiopathic ventricular fibrillation was identified, and a dual-chamber implantable cardioverter-defibrillator was implanted. The report is significant because it underscores that idiopathic ventricular fibrillation can occur perioperatively even after negative multimodality workup, informing risk assessment and monitoring around surgery.
Ganthan RR, Isber R, Elcicek A et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Diffusion tensor cardiovascular magnetic resonance differentiates pediatric dilated and hypertrophic cardiomyopathies.
This European Journal of Radiology study evaluated diffusion tensor cardiovascular magnetic resonance (DTI) to differentiate pediatric dilated versus hypertrophic cardiomyopathies using quantitative diffusion metrics including apparent diffusion coefficient (ADC) and fractional anisotropy (FA). The key finding was that DTI-derived microstructural measures provided discriminatory information beyond conventional CMR functional and tissue characterization. This is significant because it supports noninvasive assessment of myocardial microstructure to improve diagnostic classification and potentially risk stratification in children with cardiomyopathy.
Juárez JT, Tobón SH, Patrón Chi SA et al. · European journal of radiology · (2026) · View on PubMed ↗ · Free PDF ↗
Multimodality imaging characterization of Perugini scintigraphic grades in transthyretin amyloid cardiomyopathy: a single-center experience.
This single-center study assessed multimodality imaging characteristics across Perugini scintigraphic grades in transthyretin amyloid cardiomyopathy (ATTR-CM) using technetium-99m pyrophosphate (99mTc-PYP) scintigraphy. By comparing clinical and imaging features between Perugini grades 2 and 3 (both considered diagnostic), the study evaluated whether these grades reflect distinct phenotypes and how diagnostic yield varies by grade. The significance is that refining interpretation of Perugini grade differences could improve noninvasive diagnostic accuracy and prognostic/phenotypic understanding in ATTR-CM.
Bucius P, Zarambaite E, Lusaite K et al. · Journal of cardiovascular imaging · (2026) · View on PubMed ↗ · Free PDF ↗
Multimodal phenotypic clustering predicts cardiac outcomes in Fabry disease.
This Orphanet Journal of Rare Diseases study developed a multimodal phenotypic clustering framework integrating sex, genetics, clinical assessments, ECG, imaging, and biomarkers to predict cardiac outcomes in Fabry disease. Using 525 “visit years” across 98 participants (including 60 females and 60 with classic mutations), it assessed how each modality contributed to characterizing progression and forecasting adverse cardiovascular events. The significance is that a comprehensive, data-driven multimodal approach may better predict cardiac deterioration in Fabry disease than any single assessment alone.
Shemesh E, Feigin P, Tan CY et al. · Orphanet journal of rare diseases · (2026) · View on PubMed ↗ · Free PDF ↗
Phenotype, genotype and prognosis of Apical Hypertrophic Cardiomyopathies: A French multicentric cohort.
This French multicenter cohort study evaluated phenotype, genotype, and prognosis in 201 patients with apical hypertrophic cardiomyopathy (ApHCM) confirmed by echocardiography, cardiac magnetic resonance, and genetic testing, compared with 419 patients with non-apical HCM. ApHCM showed distinct genotype–phenotype and prognostic features relative to non-apical HCM (with Fabry disease and one amyloidosis case excluded from the ApHCM analyses). These findings refine risk stratification and genetic counseling for ApHCM patients in clinical practice and support more tailored follow-up strategies.
Martel H, Lucas C, Benjelloun H et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗
AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich Ataxia: A Nonrandomized Clinical Trial.
In a nonrandomized clinical trial, adults with Friedreich ataxia cardiomyopathy caused by pathogenic variants in the frataxin (FXN) gene received systemic AAVrh.10hFXN, an AAV serotype rh.10 vector delivering the normal human FXN coding sequence. The study assessed safety and preliminary efficacy of AAVrh.10hFXN based on clinical and cardiac outcomes during follow-up. If confirmed in larger controlled studies, this gene therapy could provide a disease-modifying option for FXN-deficient cardiomyopathy in Friedreich ataxia.
Crystal RG, Weinsaft JW, Kaminsky SM et al. · JAMA cardiology · (2026) · View on PubMed ↗ · Free PDF ↗
Sudden Death in Young Competitive Athletes Due to Arrhythmogenic Cardiomyopathy: A 4-Decade National Referral Center Experience.
Using the North-East Italy registry of juvenile sudden cardiac death (≤40 years) from 1985–2024, this national referral center study examined arrhythmogenic cardiomyopathy (ACM) as a cause of sudden death in competitive athletes under the 1994 and 2010 diagnostic criteria. ACM accounted for 29% of athlete sudden deaths and the study characterized clinical and pathology features of these cases. The results highlight the ongoing burden of ACM-related sudden death in athletes and inform how screening criteria and diagnostic approaches may need to evolve.
De Gaspari M, Pilichou K, Zorzi A et al. · Circulation. Arrhythmia and electrophysiology · (2026) · View on PubMed ↗ · Free PDF ↗
Left Atrial Reservoir Strain for Predicting Progression to End-Stage in Hypertrophic Cardiomyopathy.
This cohort study analyzed 925 patients with hypertrophic cardiomyopathy (HCM) followed for progression to end-stage HCM (left ventricular ejection fraction <50% without reversible causes), with a CMR subcohort of 491 patients. The key finding was that left atrial reservoir strain measured by CMR was associated with subsequent progression to end-stage HCM over a median follow-up of 6.5 years. Clinically, this supports using left atrial reservoir strain as a prognostic imaging biomarker to identify HCM patients at higher risk for deterioration and guide closer management.
Kwak S, Jeong MH, Park CS et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗
Myocarditis & Immune/Inflammatory Cardiac Syndromes
Immune Checkpoint Inhibitor-Associated Myocarditis: A Retrospective Case Series.
This retrospective case series studied immune checkpoint inhibitor (ICI)-associated myocarditis in five patients treated at Mayo Clinic Florida (2019–2024), including cases categorized as definite/probable/possible based on cardiac MRI (CMR) and histopathology when available. It found that myocarditis developed 5–30 days after starting anti–PD-1 therapy, with a median patient age of 74 years and four of five patients being male. The clinical significance is that it highlights the early timing and diagnostic role of CMR in recognizing potentially fatal myocarditis as an immune-related adverse event of anti–PD-1 treatment.
Monsanto MA, Schneider A, Chirila RM et al. · Romanian journal of internal medicine = Revue roumaine de medecine interne · (2026) · View on PubMed ↗ · Free PDF ↗
Long-term CMR Findings in Pediatric COVID-19 Related Myocarditis.
This retrospective study evaluated long-term cardiac magnetic resonance (CMR) findings in 21 pediatric patients (mean age 13.1 years) with suspected COVID-19–related myocarditis, using the 2009 Lake Louise criteria and imaging timepoints of <30 days, 30–364 days, and ≥365 days. While acute abnormalities were often favorable, the study assessed whether myocarditis-related CMR abnormalities persisted across midterm and long-term intervals. These findings are clinically important for defining the durability of myocardial injury after COVID-19–associated myocarditis/MIS-C in children and for guiding follow-up imaging strategies.
Vasquez Choy AL, Adebo DA, Patel MD et al. · Pediatric cardiology · (2026) · View on PubMed ↗ · Free PDF ↗
Chest Pain With Immune Checkpoint Inhibitor Therapy: Harnessing the Power of Multimodality Imaging.
This case report examined a 53-year-old woman with metastatic lung adenocarcinoma receiving the immune checkpoint inhibitor pembrolizumab who developed worsening pleuritic chest pain consistent with a cardiovascular immune-related adverse event. Serial chest CT showed progressive pericardial thickening and the clinical workup supported immune-mediated pericarditis/pericardial involvement rather than alternative causes such as pneumonia or pulmonary embolism. The report is significant because it emphasizes multimodality imaging to recognize and diagnose rare ICI-associated pericarditis early, enabling timely management.
Roy R, Liu L, Li H et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Fulminant Eosinophilic Myocarditis After Sequential Biologic Therapy in Ulcerative Colitis.
This JACC Case Reports article studied a 35-year-old man with ulcerative colitis who developed fulminant eosinophilic myocarditis after sequential biologic therapy, most recently vedolizumab, and corticosteroid withdrawal. He presented with cardiogenic shock, severe biventricular dysfunction (left ventricular ejection fraction 10%), and hypereosinophilia (2,154/µL), with cardiac magnetic resonance suggesting diffuse myocardial involvement and endomyocardial biopsy confirming eosinophilic myocarditis. The case is clinically important because it links biologic sequencing and steroid withdrawal to life-threatening eosinophilic myocarditis and supports rapid biopsy/CMR-based diagnosis in unstable patients.
Lee J, Kim D, Hong D et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Clinical and Cardiac Magnetic Resonance Phenotype of Probable Viral versus Probable Immune-mediated Acute Myocarditis.
This European Journal of Heart Failure study compared clinical presentation, CMR phenotype, and prognosis between clinically defined probable viral myocarditis (pVM) and probable immune-mediated myocarditis (pIM) in patients referred for CMR at two tertiary centers. pVM was defined as myocarditis within 14 days of a documented infection, while pIM was defined as acute myocarditis in patients with known systemic autoimmune disease, and the study assessed whether these groups differed in CMR features and outcomes. The significance is that CMR phenotyping may help distinguish viral versus immune-mediated acute myocarditis when endomyocardial biopsy is not routinely performed.
Bernhard B, Fabian E, Stoyanov K et al. · European journal of heart failure · (2026) · View on PubMed ↗
Benralizumab as a steroid-sparing rescue therapy in ANCA-negative eosinophilic granulomatosis with polyangiitis: real-world experience from three cases and review of the literature.
This real-world report described three patients with ANCA-negative eosinophilic granulomatosis with polyangiitis (EGPA) treated with benralizumab, an anti–IL-5 receptor monoclonal antibody that rapidly depletes eosinophils, alongside a literature review. Benralizumab was used as steroid-sparing rescue therapy, with changes in eosinophil kinetics and clinical/laboratory measures reported across the cases. These observations support benralizumab as a potential targeted option for refractory or steroid-dependent ANCA-negative EGPA driven by type 2 inflammation.
Sebastian A, Kosałka-Węgiel J, Puchala M et al. · Rheumatology international · (2026) · View on PubMed ↗ · Free PDF ↗
Pericardial Disease Pathways and Imaging
Pathway for the Diagnosis and Management of Pericardial Disease: Contemporary Perspective.
This contemporary perspective studied diagnostic and management pathways for pericardial disease across clinical scenarios including acute pericarditis, pericardial effusion, cardiac tamponade, effusive-constrictive pericarditis, and constrictive pericarditis. It found that recent European Society of Cardiology and American College of Cardiology guidance emphasizes improved phenotyping, multimodal imaging, and targeted immunomodulatory therapies, but real-world implementation varies. The clinical significance is that the proposed pathway-based framework can standardize decision-making and treatment selection across urgent and non-urgent pericardial presentations.
Sivalokanathan S, Herzog E, Haider SW et al. · Critical pathways in cardiology · (2026) · View on PubMed ↗
ECMO-Supported Pericardiectomy in Constrictive Tuberculous Pericarditis With Severe Ventricular Dysfunction.
This JACC Case Reports report described a 20-year-old man with constrictive tuberculous pericarditis and severe biventricular systolic dysfunction (LVEF <15%) who deteriorated despite empirical antituberculosis therapy and heart failure treatment. The key intervention was ECMO-supported radical pericardiectomy after ongoing cardiogenic shock, with the case highlighting the feasibility of mechanical circulatory support in this rare presentation. Clinically, it provides practical guidance for managing life-threatening constrictive pericarditis complicated by profound ventricular failure.
Elmorshidy M, Helal A, El-Din M et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Atrial Fibrillation & Rhythm Control Evaluation
CMR Detected Atrial Structural and Functional Remodeling in AF HFrEF: Ablation vs Medical Rate Control.
This study used cardiac magnetic resonance (CMR) to assess biatrial structural/functional remodeling and exercise capacity in atrial fibrillation (AF) patients with heart failure with reduced ejection fraction (HFrEF) enrolled in the CAMERA-MRI and CAMERA-MRI II trials, comparing catheter ablation (CA) versus medical rate control (MRC). CMR detected atrial remodeling differences between treatment strategies, including changes in atrial contractile function and associated exercise capacity outcomes. These findings support CMR as a mechanistic tool to evaluate whether CA improves atrial performance beyond rate control in AF-HFrEF patients, with potential implications for selecting rhythm-control strategies.
Cho KK, Segan L, Kistler PM et al. · JACC. Clinical electrophysiology · (2026) · View on PubMed ↗
Congenital Heart Disease Imaging & Interventions
Intraoperative Cardiac Events During Pediatric Cardiac Magnetic Resonance Imaging Under Anesthesia: A Retrospective Cohort Study.
This single-center retrospective cohort study assessed intraoperative cardiovascular instability in pediatric patients (≤18 years) with congenital heart disease undergoing cardiac magnetic resonance (MRI) under anesthesia from 2013–2025. Using a composite framework for intraoperative cardiovascular instability, it quantified the incidence of intraoperative cardiac events and identified predictors of instability during pediatric CMR. The results are significant for improving peri-anesthesia risk stratification and monitoring strategies in children undergoing non-surgical but physiologically vulnerable imaging procedures.
Wingert T, Liang J, Feldman K et al. · Paediatric anaesthesia · (2026) · View on PubMed ↗ · Free PDF ↗
Prospective Midterm Outcomes of the PULSTA Self-Expandable Transcatheter Pulmonary Valve: The PULSTA CE Approval Study.
This prospective, multinational PULSTA CE approval study evaluated midterm safety, hemodynamic performance, and durability of the PULSTA self-expandable transcatheter pulmonary valve in 58 patients across 11 centers in 6 countries. The key findings (as reported in the truncated abstract) focus on the valve’s midterm clinical performance and durability in patients with congenital or acquired right ventricular outflow tract dysfunction requiring pulmonary valve replacement. Scientifically and clinically, these results support the feasibility of a self-expanding transcatheter pulmonary valve platform to reduce repeat surgical interventions from prosthetic degeneration.
Lee SY, Kim GB, Carminati M et al. · Circulation. Cardiovascular interventions · (2026) · View on PubMed ↗
Multimodality approach to the no-entry ventricle for VT ablation: first European experience of the RA-to-LV percutaneous access-a case report.
This European Heart Journal Case Reports article presented the first European experience of RA-to-LV percutaneous access for ventricular tachycardia (VT) ablation in an 81-year-old man with rheumatic heart disease and double mechanical left-sided valve replacement. Because conventional retrograde or transseptal approaches were not feasible due to prosthesis-related risk, the team used an RA-to-LV puncture through the inferoseptal process as an alternative access route. The case supports the feasibility of RA-to-LV access as a practical strategy for VT ablation when standard catheter pathways are contraindicated by mechanical valves.
Sanaú J, García JR, Comín-Colet J et al. · European heart journal. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Shape and flow characterization of the pulmonary arteries after the LeCompte maneuver.
This retrospective single-center study applied statistical shape modeling (SSM) and 4D flow cardiovascular magnetic resonance (CMR) to characterize pulmonary artery (PA) geometry and flow in patients with transposition of the great arteries (TGA) after the arterial switch operation (ASO), compared with age/size-matched controls. The key finding was that PA shape and flow metrics derived from SSM and 4D flow differed in post-ASO TGA patients relative to controls, linking geometry to altered hemodynamics. Clinically, this provides an imaging framework to quantify PA remodeling after ASO and may help identify patients at risk for future right-sided outflow or flow-related complications.
Bunag JE, Casto T, Phan TT et al. · JRSM cardiovascular disease · (2026) · View on PubMed ↗ · Free PDF ↗
Filling the Gaps: Generating 4D Dense Cardiac Anatomy from Sparse CMR for Enhanced Tetralogy of Fallot Assessment.
This study developed and validated a deep learning pipeline to generate 4D dense cardiac anatomy from sparse CMR-like slices for repaired tetralogy of Fallot (rToF), using CT-derived isotropic 3D whole-heart segmentations to train the model. The key finding was that the model could reconstruct comprehensive 3D four-chamber anatomy despite the anisotropic resolution, inter-slice inconsistencies, and motion artifacts typical of standard CMR acquisitions. This is significant because it bridges CT spatial resolution with CMR clinical accessibility, potentially improving rToF assessment and follow-up planning.
Mauger C, Deng Y, Xu Y et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
Valvular Disease (Mitral Regurgitation) and AI Workflow
Advances in artificial intelligence for the evaluation of mitral regurgitation.
This article is a narrative review summarizing current evidence for artificial intelligence (AI) across the diagnostic pathway for mitral regurgitation (MR), from upstream screening to advanced multimodality imaging. The key finding is that AI tools (including digital stethoscopes and deep learning ECG models) are largely used as enrichment strategies for early detection/risk stratification rather than standalone definitive diagnostics, with ongoing work needed for clinical integration. This is significant because it maps where AI is already improving MR workflow and where validation and standardization remain critical.
Sanchez AA, Sadeghpour A, Asch FM · Current opinion in cardiology · (2026) · View on PubMed ↗
Heart Failure Risk Stratification with Multimodal CMR
Long-term Prognostic Value of Stress Cardiovascular Magnetic Resonance in Patients with Hypertension without known coronary artery disease.
This cohort study evaluated the long-term prognostic value of vasodilator stress cardiovascular magnetic resonance (CMR) perfusion in patients with hypertension but no known coronary artery disease (CAD). It found that stress CMR parameters were associated with subsequent major cardiovascular events (MACE), defined as cardiovascular death or non-fatal myocardial infarction (MI), over follow-up from 2008–2022. The scientific significance is that stress CMR may enable risk stratification and potential CAD screening beyond traditional clinical assessment in hypertensive patients without known CAD.
Houssany-Pissot S, Garot J, Duhamel S et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗
Incremental Prognostic Impact of Quantitative Perfusion CMR and T1 Mapping in Patients with Heart Failure.
This prospective cohort study evaluated patients with clinically diagnosed heart failure who underwent CMR between 2017 and 2024 to determine the incremental prognostic value of combining quantitative perfusion CMR with T1 mapping-derived diffuse fibrosis. The key finding was that stress/rest myocardial blood flow and perfusion reserve (MPR), together with diffuse fibrosis measures, provided additional prognostic information beyond either component alone. Scientifically and clinically, it supports integrated CMR phenotyping to improve risk prediction in heart failure.
Takafuji M, Sia CH, Anderton T et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
Vascular/Structural Remodeling in Congenital or Vascular Disease
Pathophysiologic Consequences of Early Coarctation Stenting in a Longitudinal Porcine Model.
This longitudinal preclinical study examined early coarctation (COA) stenting in a porcine model, comparing sham, COA control, and COA stent groups with serial dilations to adult aortic diameters. The key finding was that early stent implantation produced distinct, time-dependent pathophysiologic cardiovascular consequences compared with controls over the 20-week follow-up. These results are significant for guiding the timing and expected long-term vascular remodeling risks of next-generation COA stent strategies.
Gober LM, Stellon MA, Culver MA et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiovascular Imaging in Athletes & Exercise Stress Testing
Indications, protocols, and interpretation of cardiovascular imaging for the evaluation and management of athletes: a clinical consensus statement of the European Association of Preventive Cardiology (EAPC) and the European Association of Cardiovascular Imaging (EACVI) of the European Society of Cardiology (ESC), Part 2: Cardiovascular magnetic resonance, cardiac CT, and nuclear imaging.
This European consensus statement studied how to use cardiovascular magnetic resonance (CMR), cardiac computed tomography (CT), and nuclear imaging to evaluate athletes and distinguish physiological cardiac remodelling from pathology. It found that a multimodality imaging strategy—tailoring modality choice to specific clinical questions such as structure/function, coronary anatomy, and tissue characterization—improves risk assessment for exercise-related adverse events. The guidance is clinically significant because it standardizes indications, protocols, and interpretation across advanced imaging tests for both competitive and recreational athletes.
Maestrini V, Gati S, D’Ascenzi F et al. · European journal of preventive cardiology · (2026) · View on PubMed ↗
Indications, protocols, and interpretation of cardiovascular imaging for the evaluation and management of athletes. A Clinical Consensus Statement of the European Association of Preventive Cardiology (EAPC) and the European Association of Cardiovascular Imaging (EACVI) of the European Society of Cardiology (ESC). Part 2-Cardiovascular Magnetic Resonance, Cardiac CT and Nuclear Imaging.
This European consensus statement studied how to use cardiovascular magnetic resonance (CMR), cardiac CT, and nuclear imaging in athletes to evaluate cardiovascular substrates linked to exercise-related adverse events. It concluded that CMR, CT, and nuclear imaging provide complementary information (cardiac structure and function, coronary anatomy, and tissue characterization) and should be integrated into a refined diagnostic workflow. The scientific significance is that it provides practical, modality-specific recommendations to improve differentiation of normal athletic adaptation from concealed cardiovascular disease.
Maestrini V, Gati S, D’Ascenzi F et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗
Indications, protocols, and interpretation of cardiovascular imaging for the evaluation and management of athletes: a clinical consensus statement of the European Association of Preventive Cardiology (EAPC) and the European Association of Cardiovascular Imaging (EACVI) of the ESC: Part 1-Exercise imaging.
This European consensus statement studied exercise imaging—especially exercise stress echocardiography (ESE)—in competitive and recreational athletes to distinguish physiological adaptations from pathological conditions. It found that ESE is particularly useful for assessing cardiac reserve, unmasking concealed cardiomyopathies, and stratifying risk during exertion. The clinical significance is that it offers standardized indications, protocols, and interpretation to improve detection of exercise-related cardiovascular risk in athletes.
D’Ascenzi F, Sanz-de la Garza M, Maestrini V et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗
Indications, protocols, and interpretation of cardiovascular imaging for the evaluation and management of athletes: a clinical consensus statement of the European Association of Preventive Cardiology (EAPC) and the European Association of Cardiovascular Imaging (EACVI) of the ESC: Part 1-Exercise imaging.
This European consensus statement studied exercise imaging, focusing on exercise stress echocardiography (ESE), for evaluating cardiovascular function in athletes and differentiating normal remodelling from disease. It reported that ESE can assess cardiac reserve, reveal concealed cardiomyopathies, and support risk stratification in both competitive and recreational athletes. The clinical significance is that it provides actionable guidance for when and how to perform and interpret ESE to improve athlete safety.
D’Ascenzi F, Sanz-de la Garza M, Maestrini V et al. · European journal of preventive cardiology · (2026) · View on PubMed ↗
Non-cardiac/Basic Science & Other Mechanistic Biology (non-clinical)
Single-Port Robotic Transanal Minimally Invasive Surgery for Rectal Cancer: A Novel Approach With FishBowl-Early Case Series.
The study evaluated single-port robotic transanal minimally invasive surgery (SP-TAMIS) using the Da Vinci SP platform in patients with rectal cancer undergoing organ-preservation strategies after neoadjuvant chemoradiotherapy. In this early case series, the authors report feasibility of SP-TAMIS for local excision in the confined pelvic space, addressing key adoption barriers such as docking constraints. If confirmed in larger cohorts, SP-TAMIS could expand minimally invasive local cancer management and potentially support Watch-and-Wait pathways with low morbidity.
Mellano A, Pellegrino L, Salomone S et al. · Surgical laparoscopy, endoscopy & percutaneous techniques · (2026) · View on PubMed ↗ · Free PDF ↗
Protective effect of coumarin on diabetes-induced sciatic nerve damage in rats via TRPV1 modulation.
This animal study evaluated whether coumarin protects against diabetes-induced sciatic nerve damage in Wistar rats and whether the effect involves TRPV1 modulation. The key finding was that coumarin treatment improved outcomes in the diabetic neuropathy model and altered TRPV1-associated signaling pathways implicated in oxidative stress, inflammation, and apoptosis. These results are significant because they support TRPV1 as a mechanistic target and position coumarin as a candidate neuroprotective therapy for diabetic peripheral neuropathy.
Yıldızhan K, Altındağ F, Bayir MH et al. · Experimental neurology · (2026) · View on PubMed ↗
Architecture and function of holocentric CENP-A-independent inner kinetochores.
This structural study investigated how inner kinetochores are organized in the holocentric silkmoth Bombyx mori, which lacks the canonical centromere-specifying histone variant CENP-A, using cryo-EM/structural characterization of the constitutive centromere-associated network (CCAN). The authors report that the B. mori CCAN contains four previously uncharacterized centromeric subunit proteins structurally related to the Dam1/DASH complex that function to scaffold the inner kinetochore in a CENP-A-independent manner. This advances understanding of kinetochore architecture and chromosome segregation mechanisms in species with holocentric centromere biology.
Yu C, Sankaranarayanan SR, Cornilleau G et al. · Science advances · (2026) · View on PubMed ↗ · Free PDF ↗
Outcomes in laparoscopic versus robotic-assisted surgery for median arcuate ligament syndrome: a systematic review and meta-analysis.
This systematic review and meta-analysis compared outcomes of robotic-assisted median arcuate ligament release (RMALR) versus laparoscopic MAL release (LMALR) in adult patients with median arcuate ligament syndrome (MALS). The analysis synthesized perioperative and postoperative outcomes across comparative studies to determine whether one approach offers superior clinical results. Clinically, the findings aim to guide surgical approach selection for a rare vascular compression syndrome where evidence is limited.
Arabi Z, Geropoulos G, Jayawardena P et al. · Journal of robotic surgery · (2026) · View on PubMed ↗ · Free PDF ↗
The Challenge of Differentiating Mixed Histiocytosis: A Case Report.
This case report described a 69-year-old woman with multisystem histiocytosis in whom Langerhans cell histiocytosis (LCH) and Erdheim-Chester disease (ECD) were diagnosed sequentially over 7 years. The key clinical finding was the coexistence of both histiocytic disorders, illustrating the diagnostic difficulty of differentiating mixed histiocytosis when presentations overlap across organs. The report is significant because it underscores the need for careful longitudinal evaluation and diagnostic workup in patients with complex histiocytic disease.
Harris L, Arnolda R, Ogburn D et al. · Case reports in hematology · (2026) · View on PubMed ↗ · Free PDF ↗
L1CAM signaling through planar cell polarity drives SOX2 expression and lung adenocarcinoma metastasis.
This mechanistic cancer biology study investigated how L1CAM signaling regulates SOX2 expression and metastatic progenitor emergence in lung adenocarcinoma (LUAD). The authors found that L1CAM is expressed at the invasive front and in distant metastases and drives the formation/maintenance of SOX2+ metastatic progenitors, linking cell adhesion signaling to a fetal-like progenitor state. This is significant because it identifies a pathway (L1CAM→SOX2) that may be targetable to limit LUAD metastasis.
Park JS, Kaygusuz Y, Kenum C et al. · Nature communications · (2026) · View on PubMed ↗ · Free PDF ↗
Outcomes From the Multicenter ACCRU-LY-1804/CARiBOU TRIAL (Cytarabine, Acalabrutinib and Rituximab Integrated With Bortezomib-Based Outpatient Therapy) in 1st Line Mantle Cell Lymphoma.
In the phase 2 multicenter ACCRU-LY-1804/CARiBOU trial, previously untreated mantle cell lymphoma (MCL) patients received an outpatient regimen combining cytarabine and acalabrutinib with rituximab integrated with bortezomib-based therapy (alternating VR-CAP and R-cytarabine plus continuous acalabrutinib). The primary endpoint was complete metabolic response (CMR) rate, with safety, feasibility of stem cell collection, progression-free survival (PFS), and overall survival (OS) as key secondary outcomes. This regimen’s outcomes could improve first-line depth of response and treatment feasibility for MCL while maintaining manageable toxicity.
Smith SD, Sundaram S, Giri S et al. · American journal of hematology · (2026) · View on PubMed ↗
Size-resolved microelectrical effects of fine aerosol on nocturnal ozone: Evidence from field observations and statistical modeling.
Using summertime ground-based observations in Xi’an (2023–2025), this field study combined generalized additive models (GAM), partial least squares structural equation modeling (PLS-SEM), and a simplified interfacial contribution model to test whether particle electrical properties—specifically particle charge-to-mass ratio (CMR)—influence nocturnal ozone (O3) enhancement under stable conditions. The key finding was an association between particle charge-to-mass ratio and nocturnal O3 variations, supporting a role for particulate electrical effects in O3 chemistry beyond meteorological transport. Scientifically, it suggests that aerosol electrical properties can be an additional predictor/mechanistic driver of nighttime O3 behavior, informing atmospheric modeling and mitigation strategies.
Wang Y, Zhang L, Li J et al. · Environmental research · (2026) · View on PubMed ↗
Generated automatically on June 23, 2026. Covers PubMed articles published June 16, 2026 – June 23, 2026. Summaries are AI-generated; always consult the original publication for clinical or research decisions.