What's New in Cardiac MRI? — June 30, 2026
AI-summarised digest of 63 PubMed articles on Cardiac MRI published in the last 7 days.
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What’s New in Cardiac MRI?
June 30, 2026 · 63 articles · 15 research themes · covering June 23, 2026 – June 30, 2026
Overview
Across this week’s set of studies and reviews, a dominant theme is the move toward earlier and more precise cardiovascular risk stratification using advanced imaging—especially cardiac MRI—paired with better phenotyping. Multiple papers show that “subclinical” disease states (e.g., early CKD with albuminuria, preclinical diastolic dysfunction, diffuse myocardial changes, and post-revascularization risk markers) can be detected before overt heart failure or major events. In parallel, CMR tissue markers (LGE/T1 mapping/ECV and related surrogates) and CMR-derived functional metrics (including novel diastolic biomarkers and RV–PA coupling) are increasingly positioned as incremental tools beyond conventional clinical criteria.
A second major thread is methodological innovation to make imaging more scalable, reproducible, and clinically deployable. Several contributions focus on acquisition optimization (respiratory training, breath-holding, in-magnet exercise protocols, and CIED-related stress CMR constraints), while others develop AI frameworks for segmentation, motion tracking, and automated anomaly detection that reduce annotation burden and improve robustness across scanners and domains. Complementing this, genetics and systems biology approaches (e.g., heritable MRI-derived traits, monocyte transcriptomic signatures, and Mendelian-randomization-driven AF mechanisms) are used to connect imaging phenotypes to underlying biology.
Finally, the digest highlights how imaging is being integrated into specialized clinical pathways—ranging from inflammatory cardiac disease (pericarditis and myocarditis/inflammatory cardiomyopathy) and sarcoidosis prognosis to cardio-oncology imaging guidance and MINOCA/MINOCA diagnostic algorithms. Together, these works reinforce a broader shift: multimodality, mechanism-aware, and risk-stratified imaging strategies are becoming central to both diagnosis and long-term management.
Cardiac MRI Stress Perfusion & Ischemia Risk Stratification
Photon-counting detector CT in cardiovascular imaging: technical advances, clinical applications, and future perspectives.
This article is a narrative review that studied the state of the art of photon-counting detector computed tomography (PCD-CT) for cardiovascular imaging by synthesizing technical advances, clinical applications, limitations, and future directions from literature published between January 2015 and March 2025. It found that PCD-CT enables improved spectral imaging and potential benefits for cardiovascular diagnostics, while current limitations include availability, workflow integration, and remaining evidence gaps for some clinical indications. The review provides an evidence-based roadmap for researchers and clinicians considering PCD-CT in cardiovascular imaging and highlights priorities for future validation.
Hong Z, Yao B, Wu H · The international journal of cardiovascular imaging · (2026) · View on PubMed ↗
BMIPP Imaging in Out-of-Hospital Cardiac Arrest: Exercise-Induced Vasospastic Angina With Ventricular Fibrillation.
This case report used iodine-123 BMIPP single-photon emission computed tomography (SPECT) “ischemic memory” imaging to investigate exercise-induced vasospastic angina causing out-of-hospital cardiac arrest in a 51-year-old man. Despite emergency coronary angiography showing no significant stenosis, BMIPP SPECT supported myocardial ischemia consistent with vasospastic angina as the likely trigger of ventricular fibrillation. The report suggests BMIPP SPECT may help identify ischemia when standard angiography is unrevealing and invasive spasm provocation testing is uncertain.
Aikawa H, Murai K, Seiki S et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Indications, protocols, and interpretation of cardiovascular imaging for the evaluation and management of athletes: a clinical consensus statement of the European Association of Preventive Cardiology (EAPC) and the European Association of Cardiovascular Imaging (EACVI) of the European Society of Cardiology (ESC), Part 2: Cardiovascular magnetic resonance, cardiac CT, and nuclear imaging.
This European clinical consensus statement synthesized evidence and provided guidance on indications, protocols, and interpretation of cardiovascular imaging for athlete evaluation, focusing on cardiovascular magnetic resonance (CMR), cardiac CT, and nuclear imaging. The key finding is that a multimodality imaging strategy is recommended to distinguish physiological athlete remodeling from pathological substrates associated with exercise-related adverse events. Scientifically and clinically, the consensus standardizes how advanced imaging modalities should be used to improve risk stratification in sports cardiology.
Maestrini V, Gati S, D’Ascenzi F et al. · European journal of preventive cardiology · (2026) · View on PubMed ↗
Indications, protocols, and interpretation of cardiovascular imaging for the evaluation and management of athletes. A Clinical Consensus Statement of the European Association of Preventive Cardiology (EAPC) and the European Association of Cardiovascular Imaging (EACVI) of the European Society of Cardiology (ESC). Part 2-Cardiovascular Magnetic Resonance, Cardiac CT and Nuclear Imaging.
This clinical consensus statement addressed how to use cardiovascular imaging in athletes, specifically covering cardiovascular magnetic resonance (CMR), cardiac CT, and nuclear imaging, to evaluate suspected cardiac substrates linked to exercise-related risk. The key finding is that these modalities provide complementary information (structure, function, coronary anatomy, and tissue characterization) and should be selected within a multimodality diagnostic pathway. The guidance is intended to standardize imaging workflows and interpretation to better separate normal training effects from disease.
Maestrini V, Gati S, D’Ascenzi F et al. · European heart journal. Cardiovascular Imaging · (2026) · 2 citations · View on PubMed ↗
Indications, protocols, and interpretation of cardiovascular imaging for the evaluation and management of athletes: a clinical consensus statement of the European Association of Preventive Cardiology (EAPC) and the European Association of Cardiovascular Imaging (EACVI) of the ESC: Part 1-Exercise imaging.
This consensus statement focused on exercise imaging—especially exercise stress echocardiography (ESE)—for evaluating athletes and distinguishing physiological adaptations from pathology. The key finding is that exercise imaging is recommended for assessing cardiac reserve, unmasking concealed cardiomyopathies, and stratifying risk in both competitive and recreational athletes. Clinically, it provides practical recommendations for indications, protocols, and interpretation to improve detection of exercise-related cardiovascular abnormalities.
D’Ascenzi F, Sanz-de la Garza M, Maestrini V et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗
Indications, protocols, and interpretation of cardiovascular imaging for the evaluation and management of athletes: a clinical consensus statement of the European Association of Preventive Cardiology (EAPC) and the European Association of Cardiovascular Imaging (EACVI) of the ESC: Part 1-Exercise imaging.
This European consensus statement summarized evidence and provided practical guidance on exercise imaging, with emphasis on exercise stress echocardiography (ESE), for athlete cardiovascular assessment. The key finding is that ESE can evaluate cardiac reserve, reveal hidden cardiomyopathies, and support risk stratification by differentiating physiological remodeling from disease. This standardizes how exercise imaging should be performed and interpreted to improve safety in sports participation.
D’Ascenzi F, Sanz-de la Garza M, Maestrini V et al. · European journal of preventive cardiology · (2026) · 1 citations · View on PubMed ↗
Long-term Prognostic Value of Stress Cardiovascular Magnetic Resonance in Patients with Hypertension without known coronary artery disease.
This study evaluated the long-term prognostic value of vasodilator stress cardiovascular magnetic resonance (CMR) stress perfusion in consecutive patients with hypertension but no known coronary artery disease (CAD), followed for major adverse cardiovascular events (MACE) including cardiovascular death or non-fatal myocardial infarction (MI). The key finding was that stress CMR parameters provided prognostic information for future MACE in this hypertension population without known CAD (with Cox regression used to assess each parameter’s association). Clinically, this supports using vasodilator stress CMR as a risk-stratification tool to identify hypertensive patients at higher long-term cardiovascular risk even when CAD is not previously established.
Houssany-Pissot S, Garot J, Duhamel S et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗
Cardiac MRI Tissue Characterization & Myocardial Fibrosis/Inflammation
Splenic tissue alterations in ST-elevation myocardial infarction: determinants and prognostic implications.
This retrospective study examined determinants and prognostic implications of splenic tissue alterations assessed by cardiac magnetic resonance (CMR) in STEMI patients undergoing primary percutaneous coronary intervention (within 10 days). It evaluated splenic native T1 patterns and extracellular volume (ECV) and related them to infarction patterns, myocardial function, and adverse outcomes. Scientifically, it supports a cardio-splenic axis concept by linking CMR-detected splenic changes to systemic inflammation and prognosis after STEMI.
Yin TX, Zhu GJ, Gu XY et al. · European heart journal. Cardiovascular Imaging · (2026) · 2 citations · View on PubMed ↗
MRI-derived wall thickness heterogeneity in hypertrophic cardiomyopathy and in carriers of sarcomeric gene mutations.
This study used MRI-derived wall thickness heterogeneity metrics to assess hypertrophic cardiomyopathy (HCM) and carriers of sarcomeric gene mutations who may not meet conventional absolute wall thickness criteria. It found that wall thickness standard deviation (WTSD), reflecting heterogeneity, improves identification of HCM and mutation carriers compared with relying on absolute wall thickness cut-offs. The findings are significant because they may enable earlier detection of subtle disease in sarcomere mutation carriers using CMR quantitative phenotyping.
Aquaro GD, Licordari R, Todiere G et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗
Association between particulate matter air pollution and subclinical myocardial fibrosis in structurally normal hearts: a CMR-based study.
This CMR-based study investigated whether long-term exposure to particulate matter (PM2.5 and PM10) is associated with subclinical myocardial fibrosis in patients with structurally normal hearts and no late gadolinium enhancement. It tested relationships between PM exposure and CMR mapping parameters (diffuse fibrosis/inflammation surrogates) using multivariable regression adjusted for demographic, clinical, and socioeconomic factors. The results are important because they suggest an imaging-detectable pathway by which air pollution may contribute to early myocardial remodeling even before overt structural heart disease.
Figliozzi S, Filiberti G, Catapano F et al. · European heart journal. Cardiovascular Imaging · (2026) · 3 citations · View on PubMed ↗ · Free PDF ↗
Circulating monocyte gene expression profiles associated with cardiac remodeling and incident heart failure in the Multi-Ethnic Study of Atherosclerosis.
This Multi-Ethnic Study of Atherosclerosis analysis studied whether circulating CD14+ monocyte gene expression profiles measured by Illumina microarray relate to cardiac remodeling metrics from contrast-enhanced cardiac magnetic resonance and to incident heart failure in 1,195 community participants without ischemic heart disease. Specific monocyte transcriptomic patterns were associated with cardiac imaging measures and predicted incident heart failure. These results implicate circulating monocyte biology as a mechanistic and prognostic link to non-ischemic cardiac remodeling and future heart failure risk.
Peterson TE, Hahn VS, Ding J et al. · Communications medicine · (2026) · View on PubMed ↗
Late diagnosis of late onset Fabry disease.
This BMJ Case Reports article describes a male with late-onset left ventricular hypertrophy initially misdiagnosed as hypertrophic cardiomyopathy and later presenting with decompensated heart failure, where cardiac MRI suggested cardiac amyloidosis. Endomyocardial biopsy showed myocyte hypertrophy and fibrosis but did not identify the cause, and genetic testing revealed a pathogenic variant in the GLA gene causing Fabry disease (α-galactosidase A deficiency). The case highlights the importance of considering Fabry disease in unexplained LVH and using GLA genetic testing when imaging and biopsy are non-diagnostic.
Scully TG, Chalinor H, Theuerle J · BMJ case reports · (2026) · View on PubMed ↗
Morphological and functional evaluation of the left ventricle in severe aortic stenosis with afterload mismatch: a South African single-centre, cross-sectional cardiovascular MRI-based study.
This single-centre cross-sectional CMR study compared left ventricular (LV) remodeling and systolic function in severe aortic stenosis (AS) patients with afterload mismatch versus those without, using CMR to evaluate high-gradient severe AS phenotypes. Patients with low ejection fraction high-gradient severe AS (LVEF <50%, LEF-HG) were contrasted with those with normal ejection fraction high-gradient severe AS (NEF-HG), testing the hypothesis that insufficient LV hypertrophy (LVH) leads to high wall stress and systolic dysfunction. The results could clarify the mechanistic basis of LV failure in afterload mismatch and guide interpretation of CMR phenotypes in severe AS.
Rajah MR, Doubell AF, Herbst PG · BMJ open · (2026) · View on PubMed ↗ · Free PDF ↗
A woman in her 70s with chest pain and elevated troponin T levels.
This is a clinical case report describing a woman in her 70s presenting with chest pain and markedly elevated troponin T (initially 108 ng/L, rising to 263 ng/L) with normal electrocardiogram and coronary angiography. The key finding was that despite suspicion for acute coronary syndrome, subsequent evaluation including cardiac MRI and echocardiography did not show definitive pathology, while troponin T remained persistently elevated (~270 ng/L). The significance is that persistent troponin T elevation with normal coronaries requires consideration of non-ACS causes and careful longitudinal assessment.
Bertelsen BC, Qvigstad E, Larstorp ACK et al. · Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke · (2026) · View on PubMed ↗ · Free PDF ↗
The importance of spatial resolution in detecting chronic myocardial iron remnants following hemorrhagic myocardial infarction with T2* MRI.
This work studied how spatial resolution affects detection of chronic myocardial iron remnants after hemorrhagic myocardial infarction (hMI) using T2* cardiac MRI in digital phantom simulations and ex-vivo swine hearts (n=10). The key finding was that spatial resolution (in-plane voxel size and slice thickness) significantly influenced the ability to detect iron deposits across varying signal-to-noise ratios. Clinically, optimizing T2* MRI resolution could improve noninvasive identification of persistent hemorrhage-related iron, which is relevant to prognosis after revascularized MI.
Zhang X, Yang HJ, Dharmakumar R · Biomedical physics & engineering express · (2026) · View on PubMed ↗ · Free PDF ↗
Heart Failure Risk, Pre-Heart-Failure States & Diastolic Dysfunction
Diastolic echocardiographic parameters identify pediatric kidney transplant recipients with structural myocardial alterations.
This study examined whether diastolic echocardiographic parameters can identify structural myocardial alterations in pediatric kidney transplant recipients by comparing transthoracic echocardiography with cardiovascular magnetic resonance (CMR) using native T1 mapping. The key finding was that specific diastolic echocardiographic measures were associated with CMR-detected diffuse myocardial structural changes in this pediatric transplant population. This is scientifically and clinically important because it suggests an accessible echocardiographic screening approach for early post-transplant cardiac involvement when CMR native T1 mapping is not routinely available.
von der Born J, Ubenauf TA, Sugianto RI et al. · Pediatric nephrology (Berlin, Germany) · (2026) · View on PubMed ↗ · Free PDF ↗
Cine-derived mitral annular relaxation velocity for detection of preclinical left ventricular diastolic dysfunction.
This study evaluated a novel cardiac MRI biomarker, cine-derived mitral annular relaxation velocity (CMR-MARV), for detecting preclinical left ventricular diastolic dysfunction in 236 patients at risk of heart failure enrolled in the PARABLE trial, with 25 age- and sex-matched controls. CMR-MARV measured at four mitral annular anchor points (and related diastolic strain rates from feature tracking) differentiated patients meeting ALVDD criteria from controls with diagnostic accuracy assessed by ROC analysis. If validated, CMR-MARV could provide a noninvasive CMR method to identify early diastolic dysfunction before overt clinical heart failure.
McVeigh N, Ryan D, Ryan F et al. · Magnetic resonance imaging · (2026) · View on PubMed ↗
Regional fat distribution as a determinant of mortality in populations with left ventricular systolic dysfunction: challenging the obesity paradox.
Using UK Biobank Imaging Enhancement Programme participants with cardiac magnetic resonance (CMR)-defined left ventricular systolic impairment (left ventricular ejection fraction <50%), this study examined whether regional fat distribution better predicts mortality than body mass index (BMI) alone. The key finding was that specific regional adiposity patterns were associated with mortality risk in people with left ventricular systolic dysfunction, challenging the “obesity paradox” suggested by BMI-based analyses. Scientifically and clinically, CMR-based phenotyping of fat distribution may identify metabolically adverse adiposity that BMI can miss, improving risk prediction in heart failure with reduced ejection fraction.
Khanna S, Ho W, Takeuchi F et al. · European journal of preventive cardiology · (2026) · View on PubMed ↗
Pre-heart failure in early chronic kidney disease: clinical epidemiology and treatment.
This review characterized the “pre-heart failure” state in early chronic kidney disease (CKD) (KDIGO stages G1–G3), focusing on how mild kidney dysfunction—especially with albuminuria (A2–A3)—relates to subclinical cardiac abnormalities. The key finding was that even early CKD with albuminuria is associated with cardiac structural and functional changes such as left ventricular hypertrophy, concentric remodeling, left ventricular diastolic dysfunction, and heart failure with preserved ejection fraction (HFpEF). The clinical significance is that recognizing pre-HF in early CKD could enable earlier cardiovascular risk detection and intervention before overt heart failure develops.
Zoccali C, De Caterina R, Tuttle KR et al. · European heart journal · (2026) · 1 citations · View on PubMed ↗
Right Ventricle (RV) Function, RV–PA Coupling & Pulmonary Hypertension
Prognostic Implications of RV-Arterial Coupling Estimated by CMR in a Large Cohort of Tricuspid Regurgitation Patients.
This study assessed the prognostic value of a cardiac magnetic resonance (CMR) surrogate of right ventricular–pulmonary arterial coupling in a large cohort of tricuspid regurgitation (TR) patients referred for CMR between 2019 and 2024. Right ventricular–pulmonary arterial coupling was estimated by dividing forward right ventricular stroke volume (f-RVS) by pulmonary arterial effective elastance (Ea), and the resulting metric was evaluated for association with outcomes across a spectrum of TR severity. If confirmed, CMR-based RV–PA coupling could improve risk stratification in TR beyond conventional echocardiographic measures.
Margonato D, Fukui M, Nishihara T et al. · Circulation. Cardiovascular imaging · (2026) · View on PubMed ↗
Right Ventricular Metrics as End Points in Clinical Trials: A Review.
This review article assessed the current and emerging use of right ventricular (RV) structure/function and hemodynamic parameters as endpoints in cardiovascular interventional clinical trials. It found that RV-specific imaging and hemodynamic measures are underused and inconsistently implemented, and it proposed a framework for endpoint development, validation, and broader adoption. The significance is that better-chosen RV endpoints could enable more efficient trials with smaller sample sizes and faster timelines in RV-relevant cardiovascular diseases.
Surkova E, Lakatos B, Kempton H et al. · JAMA cardiology · (2026) · View on PubMed ↗
Right Ventricular Mechanical Dyssynchrony Reflects Hemodynamic Load in Pre-Capillary Pulmonary Hypertension.
This prospective study enrolled 30 patients with pre-capillary pulmonary hypertension (PH) without intraventricular conduction delay (QRS <120 ms) and assessed right ventricular (RV) mechanical dyssynchrony using two-dimensional speckle-tracking echocardiography alongside right heart catheterization, cardiac magnetic resonance imaging, and biochemical testing. The key finding was that RV mechanical dyssynchrony reflected hemodynamic load, with dyssynchrony correlating with measures of pulmonary vascular/afterload burden rather than conduction abnormalities. Clinically, RV dyssynchrony could serve as a noninvasive marker of hemodynamic severity in pre-capillary PH.
Igata S, Tahara N, Tahara A et al. · Pulmonary circulation · (2026) · View on PubMed ↗ · Free PDF ↗
Congenital Heart Disease (CHD) Imaging & Pediatric Cardiac MRI
Apical Right Ventricular Sequestration with Left Ventricular Hypertrabeculation: Multimodal Imaging Evaluation in an Adolescent.
This JACC Case Reports study evaluated an adolescent with apical right ventricular sequestration and left ventricular hypertrabeculation using multimodal imaging. In a 14-year-old female with palpitations, failure to thrive, and recurrent respiratory infections, imaging identified apical sequestration of the right ventricle as a rare variant of double-chamber right ventricle associated with a large ventricular septal defect and biventricular dysfunction. The case is significant because it demonstrates how multimodality imaging can clarify complex congenital anatomy that may be underrecognized and guide appropriate clinical management.
De la Cruz-Pelayo J, Mélendez-Ramírez G, de la Mora-Cervantes R et al. · JACC. Case reports · (2026) · View on PubMed ↗
From metabolic to pathologic complete response: case report of Neoadjuvant Lorlatinib in Stage IIIB ALK-positive NSCLC combined with uniportal VATS.
This case report studied neoadjuvant lorlatinib in a 35-year-old non-smoking woman with stage IIIB ALK-positive non-small cell lung cancer (NSCLC) (cT1bN2bM0) undergoing uniportal video-assisted thoracoscopic surgery (VATS). After 10 weeks of lorlatinib, the patient achieved a complete metabolic response on restaging PET-CT, enabling a multidisciplinary decision to proceed with surgery. The report is significant because it supports the potential of ALK-targeted therapy to convert unresectable stage IIIB disease to a surgically manageable state.
Li R, Wang C, Li Y et al. · Journal of cardiothoracic surgery · (2026) · View on PubMed ↗ · Free PDF ↗
High Intensity Interval Training Versus Moderate Continuous Training in Adults with Congenital Heart Disease: A Randomized Controlled Trial.
This randomized controlled trial compared 12 weeks of high-intensity interval training (HIIT) versus moderate continuous training (MCT) versus control in adults with congenital heart disease (ACHD), with peak oxygen uptake (V˙O2) as the primary outcome. The key finding (as reported in the trial design/aims) was to determine whether HIIT improves exercise capacity more than MCT and to assess effects on cardiac structure/function and quality of life. The significance is that it directly tests an exercise prescription strategy to improve prognosis-related functional capacity in ACHD patients.
Mao RT, Willner JP, Pylypchuk S et al. · The Canadian journal of cardiology · (2026) · View on PubMed ↗
Evaluation of the systemic right ventricle in transposition of the great arteries using fast strain encoded cardiovascular magnetic resonance.
This prospective single-center study evaluated global and regional systolic function in patients with a systemic right ventricle (SRV) due to transposition of the great arteries after Senning/Mustard repair or in congenitally corrected TGA (ccTGA) using fast strain-encoded cardiovascular magnetic resonance (fSENC). The key finding was the ability of fSENC to quantify SRV function with global and regional strain measures aimed at detecting early impairment. The significance is that fSENC may improve assessment of SRV systolic performance in TGA patients, potentially enabling earlier risk stratification and management.
Haney AC, Ochs A, Darino J et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
Pulmonary Artery Diameters in Children, Teenagers and Young Adults Derived from Quiescent Interval Slice Selective (QISS) Magnetic Resonance Angiography.
This study analyzed CMR data from 139 children, teenagers, and young adults (6 weeks–20 years) without pulmonary artery disorders to derive pulmonary artery (PA) diameters using the contrast-free radial Quiescent Interval Slice Selective (QISS) magnetic resonance angiography technique. The key finding was that QISS enabled reliable measurement of main PA, right PA, and left PA diameters and cross-sectional areas across pediatric age ranges. This provides a safer, motion-robust method to establish normative PA dimensions and support pediatric pulmonary vascular assessment.
Zalas-Piotrowiak D, Rozewicz Juraszek M, Gabbert DD et al. · Pediatric cardiology · (2026) · View on PubMed ↗ · Free PDF ↗
Performance of Free-Running Cardiac and Respiratory Motion-Resolved Whole-Heart 5D MRI in Congenital Heart Disease Patients Using a Gadolinium Enhanced Fast-Interrupted Steady-State Sequence.
In 45 congenital heart disease (CHD) patients undergoing clinically indicated MRI, this retrospective study compared gadolinium-enhanced free-running whole-heart 5D MRI (using a fast-interrupted steady-state sequence at 1.5 T) against 2D and 3D bSSFP MRI. The key finding was that gadolinium-enhanced 5D MRI produced comparable ventricular volume and ejection fraction estimates to 2D/3D methods while maintaining acceptable image quality and practical scan times. This supports broader clinical use of gadolinium-enhanced 5D MRI for comprehensive cardiac assessment in CHD.
Roy CW, Vogeli E, Megalo A et al. · Journal of magnetic resonance imaging : JMRI · (2026) · View on PubMed ↗ · Free PDF ↗
Diagnostic accuracy of fetal cardiac magnetic resonance imaging in cardiac and thoracic vascular anomalies: a meta-analysis.
This meta-analysis evaluated the diagnostic accuracy of fetal cardiac magnetic resonance imaging (FCMRI) for detecting cardiac and thoracic vascular anomalies in prenatal populations across observational studies. FCMRI was assessed as a complementary modality to fetal echocardiography (FE) to address diagnostic limitations in complex lesions, thoracic vascular anomalies, late gestation, and poor acoustic windows. Standardized evidence on FCMRI accuracy could improve prenatal decision-making by clarifying when additional fetal imaging beyond FE is most informative.
Bhargavi C, Shenoy RD, Rassaf A et al. · BMC medical imaging · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac MRI Acquisition Optimization (Respiration/Exercise/Protocols)
Apical hypercontractility mitigates impaired diastolic filling and lower intraventricular haemodynamic forces in human bed rest.
This experimental physiology study examined how apical right ventricular hypercontractility affects impaired diastolic filling and intraventricular haemodynamic forces during prolonged physical inactivity using cardiac magnetic resonance in 24 healthy participants. Participants underwent 60 days of strict head-down tilt bed rest (AGBRESA), and CMR was used to longitudinally quantify regional contractility and intracardiac haemodynamic forces. The findings are significant because they identify a compensatory mechanism (apical hypercontractility) that may mitigate early diastolic and haemodynamic deterioration during deconditioning.
Rabineau J, Al-Darwish F, Mulder E et al. · Experimental physiology · (2026) · View on PubMed ↗
Can resting segmental strain identify obstructive coronary artery disease in chronic coronary syndrome patients referred to CABG?
This prospective study evaluated 93 patients undergoing cardiac MRI to determine how different respiratory training and breath-holding methods affect image quality and reduce respiratory motion artifacts. The key finding was that specific respiratory training/breath-hold strategies improved cardiac MRI image quality compared with less effective approaches. Optimizing patient respiratory preparation can reduce motion artifacts and improve the reliability of cardiac MRI acquisitions in routine practice.
Rösner A, Kjønås D, Sandberg ML et al. · Cardiology · (2026) · View on PubMed ↗
Applicability of Stress Cardiac Magnetic Resonance Imaging in Patients With Cardiac Implantable Devices: A Systematic Review.
This systematic review evaluated the applicability of stress perfusion cardiovascular magnetic resonance (CMR) in patients with cardiac implantable electronic devices (CIEDs) by searching multiple databases for studies reporting CMR compatibility, safety, and image quality. Only eight studies met inclusion criteria, and the review synthesized findings on image quality, scanner/device compatibility and safety, and device-specific protocols/exclusion criteria. The work is clinically significant because it clarifies practical constraints for safely extending stress CMR to CIED patients, where evidence remains limited.
Zakavi S, Khorgami MR, Babaee P et al. · Cardiology research and practice · (2026) · View on PubMed ↗ · Free PDF ↗
Feasibility of real-time in-magnet exercise cardiovascular MRI with an individualized exercise protocol: Quantitative assessment at low, intermediate, and high exercise intensities.
This study evaluated the feasibility of real-time in-magnet exercise cardiovascular MRI (ExCMR) using an individualized supine exercise protocol to reach symptom- or fatigue-limited peak effort. The key finding was that using age-predicted maximal heart rate (APMHR%) and Borg RPE enabled quantitative image acquisition at low, intermediate, and high exercise intensities. This is significant because it advances practical implementation of in-bore ExCMR, a technique that can combine imaging with physiological provocation.
Crabtree CD, Stoner J, Chandrasekaran PS et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
AI/Deep Learning for Cardiac MRI Segmentation, Tracking & Biomarkers
Scalable Left Ventricular ROI Annotation for Stress Perfusion Cardiac MRI using Deep Learning with Visual Refinement.
This study developed a scalable, annotation-efficient deep learning framework for left-ventricular (LV) region-of-interest (ROI) localization in low signal-to-noise ratio stress perfusion cardiac MRI, using a pretrained U-Net based on the Multi-Centre, Multi-Vendor, and Multi-Disease (M&Ms) cine CMR dataset with visual refinement. The proposed approach improved LV-centered ROI extraction for stress perfusion CMR while reducing the need for extensive manual annotations. This enables more reliable preprocessing for downstream AI-based stress perfusion analysis, improving scalability for clinical and research cardiac MRI workflows.
Kalashami MP, Elshibly M, Shergill S et al. · Journal of imaging informatics in medicine · (2026) · View on PubMed ↗
Deep learning and red deer optimiser for automatic cardiovascular disease identification on magnetic resonance images.
This paper developed an automated cardiovascular disease identification framework (ACVD-RDODL) that combines deep learning with the Red Deer Optimiser (RDO) for analysis of cardiovascular magnetic resonance (MRI) images. The key finding is that the proposed pipeline, after image enhancement (e.g., Wiener filtering and dynamic histogram equalization), can automatically detect cardiovascular anomalies using AI-assisted feature selection/optimization. The significance lies in providing a potentially scalable method for automated CVD detection from MRI, which could reduce reliance on manual interpretation.
Singh A, Agarwal H, Singh AP et al. · Scientific reports · (2026) · View on PubMed ↗ · Free PDF ↗
Experimentally validated dual-band GHz metamaterial perfect absorber biosensor with negative-index response and AI-assisted electromagnetic analysis for breast cancer dielectric discrimination.
This proof-of-concept study presented and experimentally validated a dual-band GHz metamaterial perfect absorber biosensor designed for dielectric-sensitive electromagnetic sensing, with AI-assisted broadband spectral analysis for breast cancer dielectric discrimination. The key finding was near-unity absorption at 6.0 GHz and 9.1 GHz with engineered negative-index behavior, and experimental absorption exceeding 92.5% and 99.8% at the resonant frequencies matching simulations. The significance is that it demonstrates a potentially high-sensitivity, PCB-fabricated microwave biosensing platform that could support noninvasive breast cancer tissue characterization.
Hamza MN, Islam MT, Koziel S et al. · Biosensors & bioelectronics · (2026) · View on PubMed ↗ · Free PDF ↗
ContiMorph: An unsupervised learning framework for cardiac motion tracking with time-continuous diffeomorphism.
This paper introduced ContiMorph, an unsupervised learning framework for time-continuous cardiac motion tracking in cardiac image sequences. By combining a frame-aware U-Net with a time-embedded transformer to learn temporally continuous intra-frame motion fields (avoiding reliance on scaling-and-squaring integration), ContiMorph improves motion tracking accuracy over methods constrained to discrete Lagrangian fields. This could enhance CMR/echo-derived functional assessment and downstream diagnosis by producing more temporally consistent cardiac motion estimates.
Jiang M, Ruan X, Zheng L et al. · Medical image analysis · (2026) · View on PubMed ↗
Influence of Sb-doping on structural, optical and UV photodetector properties of CdS thin films.
This study investigated how antimony (Sb) doping affects the structural, optical, and ultraviolet (UV) photodetector properties of cadmium sulfide (CdS) thin films fabricated by nebulizer spray pyrolysis (NSP) on glass. X-ray diffraction (XRD) showed a hexagonal crystal structure for all films, and the 2 wt% Sb-doped CdS film had the highest crystallinity with FESEM indicating larger, more densely packed grains that enhanced UV photodetection performance. These materials-processing and characterization results support Sb-doped CdS as a tunable route to improved UV photodetectors.
Murahari P, Alagarasan D, Hegde SS et al. · Scientific reports · (2026) · View on PubMed ↗ · Free PDF ↗
Hierarchical Semantic Concept Modeling for Generalizable Myocardial Pathology Segmentation on Multisequence CMR Images.
This study developed and evaluated HSCM-Net, a hierarchical semantic concept modeling deep learning framework for generalizable myocardial pathology segmentation on multisequence cardiac MRI (CMR) images. The key finding is that integrating hierarchical semantic concept modeling of multisequence inputs and labels improves segmentation robustness under cross-domain distribution shifts compared with conventional approaches. Scientifically and clinically, better generalization for scar/edema segmentation can enable more reliable quantification of myocardial infarction severity across scanners and sites.
Dong J, Li L, Huang L et al. · IEEE transactions on neural networks and learning systems · (2026) · View on PubMed ↗
Cardiovascular Genetics & Genetically Informed Imaging Phenotypes
Hundreds of cardiac MRI traits derived using 3D diffusion autoencoders share a common genetic architecture.
This UK Biobank study used a 3D diffusion autoencoder to derive hundreds of latent cardiac MRI traits from temporally resolved cardiac MRI in 71,017 participants and then tested whether these traits share genetic determinants via genome-wide association study. The derived 3D diffusion autoencoder traits were reproducible and heritable (heritability h2 ~4–18%) and the genome-wide association analyses identified 89 significant common variants across 42 loci, indicating a common genetic architecture across many MRI-derived traits. The work supports diffusion-autoencoder cardiac phenotypes as scalable, genetically informative biomarkers for cardiometabolic risk.
Ometto S, Chatterjee S, Vergani AM et al. · Nature communications · (2026) · View on PubMed ↗
Multiomics Insights Into the Role of Spondin-1 in the Pathogenesis and Prognosis of Atrial Fibrillation.
This study used integrative multiomics to identify molecular drivers of atrial fibrillation (AF), prioritizing the protein SPON1 (spondin-1) through Mendelian randomization and colocalization of plasma protein quantitative trait loci (pQTL) and atrial expression quantitative trait loci (eQTL) with AF genome-wide association studies. The key finding was that SPON1 emerged as a priority candidate and was further supported by single-nucleus RNA sequencing, spatial transcriptomics, and experimental validation. These results suggest SPON1 as a potential mechanistic target and biomarker for AF pathogenesis and prognosis.
Long X, Zhang Y, Gao X et al. · Journal of the American Heart Association · (2026) · View on PubMed ↗ · Free PDF ↗
Inflammatory Cardiovascular Disease (Myocarditis/Pericarditis/IL-1)
Management of pericarditis: recent advances.
This narrative review studied recent advances in the management of pericarditis, focusing on mechanism-based, risk-stratified, and imaging-supported approaches. It found that diagnosis remains clinical but that inflammatory biomarkers and multimodality imaging—especially cardiac magnetic resonance—are increasingly used to improve diagnostic confidence, differential diagnosis, and therapeutic decisions, with aspirin forming part of treatment for most acute idiopathic or presumed viral cases. The review is clinically significant because it consolidates evolving evidence into practical, risk-guided management strategies for common emergency and cardiology presentations.
Imazio M · Polish archives of internal medicine · (2026) · View on PubMed ↗
Cardiac Troponin release, myocardial function and inflammation in patients with takotsubo syndrome: a cardiac magnetic resonance study.
This cardiac magnetic resonance study enrolled 94 patients with acute takotsubo syndrome and examined how peak high-sensitivity troponin T release relates to myocardial edema measured by CMR T2 mapping and to systemic inflammatory biomarkers. Patients with higher peak troponin T (≥28.8× upper limit of normal) showed stronger associations with myocardial edema and inflammatory biomarker profiles than those with lower troponin T. The results support a link between troponin-defined myocardial injury, CMR-detected edema, and systemic inflammation in takotsubo syndrome, informing pathophysiology and risk assessment.
Arcari L, Camastra G, Ciolina F et al. · The international journal of cardiovascular imaging · (2026) · View on PubMed ↗
Time-dependent effects of interleukin-1 blockade by anakinra in myocarditis and inflammatory cardiomyopathy.
This clinical study assessed time-dependent outcomes of interleukin-1 (IL-1) blockade with the IL-1 receptor antagonist anakinra in 42 consecutive patients with definite myocarditis or inflammatory cardiomyopathy (Infl-CMP), diagnosed by cardiac magnetic resonance with or without endomyocardial biopsy. The key finding was that clinical outcomes varied over time according to treatment exposure and discontinuation patterns of anakinra. The significance is that it informs how long IL-1 blockade may need to be continued and how stopping may affect recovery in inflammatory cardiomyopathy.
Peretto G, Villatore A, Trezza AF et al. · European journal of heart failure · (2026) · View on PubMed ↗
A forgotten cause of chest pain in the United States: a case report on acute rheumatic fever.
This case report described acute rheumatic fever (ARF) as an uncommon cause of chest pain in the United States in a young patient following untreated Group A Streptococcus (GAS) infection. The key finding was that the diagnosis relied on the revised Jones criteria, including serologic evidence of recent GAS infection, despite ARF being rare and therefore easy to miss. The clinical significance is heightened awareness that ARF can present with cardiac involvement (e.g., myocarditis/arrhythmias) and should be considered when chest pain and inflammatory/cardiac findings follow suspected GAS exposure.
Miller JA, Kim R, Kadiyala M et al. · Journal of medical case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Pathway for the Diagnosis and Management of Pericardial Disease: Contemporary Perspective.
This contemporary perspective article reviewed the diagnosis and management of pericardial disease across clinical entities such as acute pericarditis, pericardial effusion, cardiac tamponade, effusive-constrictive pericarditis, and constrictive pericarditis. It proposed an updated pathway-based framework that organizes care into five key clinical scenarios (including chest pain and hemodynamic compromise) and emphasizes multimodal imaging and targeted immunomodulatory therapies aligned with recent European Society of Cardiology and American College of Cardiology guidance. Scientifically and clinically, the pathway aims to standardize phenotyping and treatment decisions to improve implementation of guideline-based care across variable real-world practice.
Sivalokanathan S, Herzog E, Haider SW et al. · Critical pathways in cardiology · (2026) · View on PubMed ↗
Cardio-Oncology Imaging & Cancer-Related Cardiovascular Risk
Multimodality imaging in the detection and management of coronary and peripheral arterial disease in patients with cancer receiving cardiotoxic antineoplastic treatments: A clinical consensus statement of the ESC Council of Cardio-Oncology and the European Association of Cardiovascular Imaging (EACVI) of the ESC.
This ESC Council of Cardio-Oncology and EACVI clinical consensus statement studied how to use multimodality cardiovascular imaging to detect and manage coronary and peripheral arterial disease in patients receiving cardiotoxic cancer therapies. It found that imaging indications generally mirror those in the general population but require adaptation to cancer-specific pathophysiology and clinical presentations, with imaging playing a central role in baseline risk assessment and treatment planning. The consensus is clinically important because it standardizes imaging strategies to improve cardiovascular outcomes in cardio-oncology patients.
Novo G, Lopez-Fernandez T, Delgado V et al. · European heart journal. Cardiovascular Imaging · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗
Efficacy of post-transplant brentuximab vedotin maintenance by pre-transplant disease status in relapsed/refractory classic Hodgkin lymphoma.
This real-world analysis evaluated whether pre-transplant disease status predicts the efficacy of post-transplant brentuximab vedotin (BV) maintenance after autologous stem cell transplant (ASCT) in adult relapsed/refractory classic Hodgkin lymphoma. The key finding (as framed by the study’s aim) was to determine how BV maintenance outcomes differ by pre-ASCT metabolic response (including complete metabolic response) and by the number of AETHERA-defined clinical risk factors. Scientifically and clinically, the results could refine which high-risk cHL patients benefit most from BV maintenance after ASCT.
Desai SH, Geyer SM, Pederson L et al. · Blood cancer journal · (2026) · View on PubMed ↗ · Free PDF ↗
Toxic and explosive risks in pharmacy: an underestimated reality.
This article reviewed toxic and explosive hazards encountered in pharmacy practice, focusing on compounding pharmacies handling carcinogenic, mutagenic, and reprotoxic (CMR) substances such as chemotherapy drugs, anesthetic gases, antibiotics, and hormones. It highlights that exposure can occur via fine powder dispersion or volatile vapors leading to secondary contamination even when standard protective equipment is used, and it also emphasizes fire/explosion risks from volatile solvents like ethanol, acetone, and ethyl ether. The significance is preventive: it supports stronger occupational safety risk assessment and control measures to reduce healthcare worker harm and environmental contamination.
Larioui KY, Khoukh K, Zekri S et al. · Presse medicale (Paris, France : 1983) · (2026) · View on PubMed ↗
Meta-analysis of survival by phased-variant ctDNA and PET response in large B-cell lymphoma.
This meta-analysis pooled end-of-treatment measurable residual disease (MRD) assessed by phased-variant circulating tumor DNA (ctDNA) with positron emission tomography (PET) response in 367 patients with large B-cell lymphoma (LBCL) treated with curative-intent frontline therapy. Undetectable MRD by phased-variant ctDNA was associated with substantially better progression-free survival than detectable MRD, with stronger risk separation when PET showed complete metabolic response (CMR). Clinically, phased-variant ctDNA MRD can refine relapse risk beyond PET response and may improve post-treatment risk stratification in LBCL.
Gordon MJ, Choo-Wosoba H, Ozcan G et al. · Blood advances · (2026) · View on PubMed ↗ · Free PDF ↗
Atherosclerosis, Microvascular Dysfunction & ANOCA/MINOCA Pathways
Oxygenation-sensitive cardiovascular magnetic resonance imaging to identify coronary microvascular and vasomotor dysfunction in angina and no obstructive coronary artery disease.
This prospective study compared oxygenation-sensitive cardiovascular magnetic resonance (OS-CMR) against vasoactive breathing manoeuvres and invasive coronary function testing (ICFT) using intracoronary acetylcholine in patients with angina and no obstructive coronary artery disease (ANOCA) with endothelial-dependent coronary microvascular dysfunction (CMVD) and healthy controls. OS-CMR was evaluated as a non-invasive, needle-free diagnostic approach to detect endothelium-dependent CMVD relative to the gold-standard ICFT. The work is significant because it targets a less invasive diagnostic pathway for CMVD, which could improve risk stratification and management in ANOCA.
Hillier E, Palmer C, Lindsay K et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗
Prognostic value of epicardial adipose tissue assessed by cardiac magnetic resonance in patients with ST-elevation myocardial infarction after successful revascularization.
This registry-based study assessed whether epicardial adipose tissue (EAT) volume measured from cardiac magnetic resonance (CMR) cine sequences predicts outcomes after successful revascularization in 540 patients with ST-elevation myocardial infarction (STEMI). Using Cox proportional hazards modeling with a composite major adverse cardiovascular events (MACE) endpoint, the study tested the association between EAT volume and subsequent MACE and explored correlations with myocardial injury markers. If EAT volume is a robust prognostic biomarker, it could support risk stratification after STEMI using a noninvasive CMR-derived measure.
Wei L, Zhao CX, Dong JX et al. · BMC medical imaging · (2026) · View on PubMed ↗ · Free PDF ↗
Feasibility and Yield of a Diagnostic Protocol for Myocardial Infarction with Non-Obstructive Coronary Arteries.
This prospective multicenter cohort study evaluated a stepwise diagnostic protocol for myocardial infarction with non-obstructive coronary arteries (MINOCA) in MINOCA patients undergoing initial invasive coronary angiography (ICA) (Dec 2020–Jun 2024). The protocol’s key finding was the feasibility and diagnostic yield of adding ad-hoc optical coherence tomography (OCT) beyond ICA to reach a final underlying diagnosis. This supports a more practical, time- and cost-aware imaging strategy to improve etiologic classification of MINOCA in real-world care.
Nishimiya K, Yosofi B, Dimitriu-Leen AC et al. · The American journal of cardiology · (2026) · View on PubMed ↗ · Free PDF ↗
Standardized MRI-Based Quantification of Epicardial Adipose Tissue Volume: Reproducibility and Agreement With Cardiac Computed Tomography.
This retrospective study evaluated a standardized MRI-based method to quantify epicardial adipose tissue volume (EATV) and tested agreement with cardiac computed tomography (CT) in 127 patients with aortic stenosis (AS) plus 11 volunteers. The key finding was that the standardized MRI approach showed reproducibility and acceptable agreement with CT for EATV measurement. This supports MRI as a radiation-free alternative for EATV assessment that can be integrated with cardiac function and tissue characterization workflows.
Gronwald J, Gersch SS, Böttiger Z et al. · Journal of magnetic resonance imaging : JMRI · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac Sarcoidosis & Systemic Inflammatory Multiorgan Involvement
Prognostic impact of 18F-fluorodeoxyglucose positron emission tomography and cardiac magnetic resonance-proven cardiac involvement in pulmonary sarcoidosis: a single centre long-term cohort study.
This single-centre retrospective cohort study evaluated histologically confirmed pulmonary sarcoidosis patients, using 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) and cardiac magnetic resonance (CMR) to diagnose cardiac sarcoidosis and assess long-term outcomes and causes of death. Cardiac involvement confirmed by FDG-PET plus CMR was associated with worse prognosis in pulmonary sarcoidosis over long-term follow-up. The findings support FDG-PET/CMR-proven cardiac involvement as a clinically important risk stratifier in pulmonary sarcoidosis, potentially guiding closer monitoring and management.
Yoshikawa S, Sato T, Komori T et al. · BMC pulmonary medicine · (2026) · View on PubMed ↗
Cardiac Tumors & Rare Cardiac Masses (Imaging-Driven)
A rare capillary type cardiac hemangioma in the right atrium.
This case report described a rare capillary-type cardiac hemangioma located in the right atrium, emphasizing diagnostic challenges and the role of advanced imaging. The key clinical finding was that multimodality imaging—including echocardiography, CT, and cardiac magnetic resonance—helped characterize the lesion preoperatively despite the tumor’s rarity and nonspecific presentation. The report underscores the value of CMR and CT in improving diagnostic accuracy for uncommon cardiac tumors and guiding management planning.
Ku L, Qiu R, Ma X · The international journal of cardiovascular imaging · (2026) · View on PubMed ↗
Blunt Trauma-Induced Atrial Fibrillation as First Sign of an Unspecified Cardiac Hemangioendothelioma.
This JACC Case Reports report described a 40-year-old man who developed blunt trauma-induced atrial fibrillation as the first presentation of an unspecified cardiac hemangioendothelioma. Imaging with cardiac magnetic resonance and PET-CT identified a large right atrial tumor obstructing inflow and encasing the right coronary artery, and radical surgical resection with vascular reconstruction was performed. The clinical significance is that it highlights trauma-associated atrial fibrillation as a possible presenting sign of rare right atrial vascular tumors and supports the diagnostic value of CMR plus PET-CT.
van Dinter S, Maathuis H, Verkroost M et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Aortic/Arterial Disease (Aortitis/Aneurysm) & Vascular Pathology
Atypical Case of Takayasu Aortitis Presenting as Embolic Stroke With Concomitant Massive Thoracic Artery Aneurysm.
This case report studied a 44-year-old woman with hypertension who presented with embolic stroke and was found to have atypical Takayasu aortitis with a concomitant massive ascending thoracic artery aneurysm (6.0 × 6.0) involving the transverse arch. She underwent open surgical repair with Dacron graft placement, and pathology showed granulomatous inflammation consistent with autoimmune or infectious etiology. The report highlights that Takayasu aortitis can present with embolic neurologic events and large thoracic aneurysms, supporting early surgical and pathologic evaluation in atypical presentations.
Henson JC, Myers JH, Cummins M et al. · Clinical case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Arrhythmias, ECG Syndromes & Sudden Cardiac Death Risk
A Case of Brugada Syndrome… or Something Else? Behind Type 1 Brugada Pattern.
This case report studied a 51-year-old man with syncope during a febrile illness who had a transient spontaneous type-1 Brugada ECG pattern. Holter monitoring revealed multifocal ventricular ectopy including non-sustained ventricular tachycardia, prompting consideration of an alternative diagnosis when overt myocardial scar or arrhythmogenic substrate is suspected. Clinically, it emphasizes that a Brugada type-1 pattern during fever should trigger careful structural/arrhythmia evaluation rather than assuming primary Brugada syndrome.
Scarà A, Borrelli A, Romano S et al. · Clinical case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Digital Twin Guided Ventricular Tachycardia Ablation: Design and Rationale of the APOLO-VT Trial.
This article describes the design and rationale of the APOLO-VT trial, which will test a digital-twin–guided, multimodal workflow integrating noninvasive ECG imaging (ECGi) with invasive electroanatomic mapping (EAM) to guide ventricular tachycardia (VT) ablation in an interventional prospective setting. The key premise is that combining ECGi-derived structural/functional substrate characterization with EAM will improve identification and durable elimination of slow-conduction VT substrate compared with incomplete substrate targeting. Clinically, the trial aims to establish feasibility, safety, and impact of this integrated mapping strategy to reduce VT recurrence and ICD therapies.
Bhagirath P, Regany M, Borràs R et al. · Journal of cardiovascular electrophysiology · (2026) · View on PubMed ↗
Mortality among adolescent and young adults in specialized substance use treatment: a Swedish register study.
This Swedish register study examined all-cause and cause-specific mortality among adolescents and young adults (ages 13–25) receiving specialized substance use treatment. Using linked national registry data from 2011–2021 and modeling predictors including sex, migrant background, parental education, convictions, and treatment variables, the study quantified mortality risks relative to the general population. The findings are significant for public health planning and for targeting prevention and follow-up interventions in this high-risk treated population.
Karlsson P, Ekendahl M, Lindner P · Child and adolescent psychiatry and mental health · (2026) · View on PubMed ↗ · Free PDF ↗
[Incremental value of CMR for the 2025 appropriate use criteria of ICD implantation in sudden cardiac death risk stratification of dilated cardiomyopathy].
This single-center retrospective study evaluated whether the 2025 appropriate use criteria (AUC/AUV) for implantable cardioverter-defibrillator (ICD) implantation predicts sudden cardiac death (SCD) in dilated cardiomyopathy (DCM) patients, and whether cardiac magnetic resonance (CMR) tissue characterization adds incremental value. The key finding was that CMR parameters based on late gadolinium enhancement (LGE) and T1 mapping improved SCD risk stratification beyond the 2025 ICD appropriateness criteria in DCM patients. This suggests that integrating CMR tissue markers with guideline-based criteria could better identify DCM patients who benefit from ICD therapy.
Zhou D, Wang LL, Lian XQ et al. · Zhonghua xin xue guan bing za zhi · (2026) · View on PubMed ↗
Generated automatically on June 30, 2026. Covers PubMed articles published June 23, 2026 – June 30, 2026. Summaries are AI-generated; always consult the original publication for clinical or research decisions.