What’s New in Cardiac MRI?

July 08, 2026 · 93 articles · 15 research themes · covering July 01, 2026 – July 08, 2026

Overview

This week’s cardiovascular literature is dominated by a push toward more precise, imaging-driven risk stratification—especially using cardiac MRI beyond traditional late gadolinium enhancement. Multiple studies (e.g., hypertrophic cardiomyopathy, AL amyloidosis, acute myocarditis, and TTR amyloidosis) show that adding quantitative tissue metrics such as extracellular volume (ECV), myocardial strain, and even novel constructs like MRI entropy can improve prognostic discrimination for major adverse events and sudden cardiac death. Together, these works reinforce a broader theme: myocardial disease is not just “present or absent” on imaging, but heterogeneous in ways that can be quantified and used to guide follow-up intensity and therapeutic decisions.

A second major theme is refining diagnosis in “overlap” syndromes where clinical presentation can mislead—ranging from MINOCA/MINOCA-like mechanisms (including coronary microembolization) to myocarditis-like conditions and stress cardiomyopathy phenotypes. Reviews and case-based evidence emphasize that standardized frameworks and timely, appropriate testing matter: transient or atypical ECG patterns, inflammatory constriction vs fixed constriction, and myocarditis that may actually reflect inherited desmosomal cardiomyopathy all highlight the need for phenotype-aware evaluation and, in selected cases, earlier genetic consideration. In parallel, several studies address arrhythmia risk and substrate characterization—using both imaging-derived scar heterogeneity and emerging data-driven approaches (e.g., electrogram-based inference of nonendocardial fibrosis) to better predict and treat ventricular arrhythmias.

Finally, the digest includes strong methodological momentum: AI automation for cardiac imaging workflows, low-field CMR feasibility, free-breathing volumetric tissue mapping, and physics/CFD validation efforts that challenge assumptions used in hemodynamic biomarker computation. These advances aim to make high-quality cardiac phenotyping more scalable and reproducible—an essential step if the prognostic gains from advanced tissue characterization are to translate into routine clinical practice.

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Cardiac MRI biomarkers & tissue characterization (LGE/ECV/T1/T2/entropy/quantitative mapping)

Diagnostic and Prognostic Utility of Mitral Annular Plane Systolic Excursion: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the diagnostic and prognostic utility of mitral annular plane systolic excursion (MAPSE) across imaging modalities (including transthoracic echocardiography, transesophageal echocardiography, and cardiovascular magnetic resonance) in relevant cardiovascular populations. The key finding was that MAPSE provides clinically useful information for diagnosis and risk prediction, with evidence supporting its measurement as a simple, fast, and potentially automatable marker of longitudinal cardiac function. This is significant because it highlights MAPSE’s potential role in clinical risk stratification despite the lack of routine guideline endorsement.

Falconer D, Fröjdh F, Wyeth N et al. · Journal of the American Heart Association · (2026) · View on PubMed ↗ · Free PDF ↗

Fully quantitative CMR rest perfusion reveals myocardial perfusion abnormality in Kawasaki disease: Association with left ventricular Remodeling.

This prospective single-center study used fully quantitative cardiac magnetic resonance (CMR) rest perfusion to characterize myocardial perfusion abnormality in 87 children with Kawasaki disease (KD) and relate it to left ventricular (LV) remodeling. Myocardial blood flow (MBF) was measured and corrected for heart rate–blood pressure product (MBFcor), and statistical analyses tested associations with remodeling indices. The study links quantitative rest perfusion abnormalities to subsequent LV remodeling, supporting CMR perfusion as a marker of myocardial injury severity in KD.

Zhou Z, Ye P, Wang C et al. · International journal of cardiology · (2026) · View on PubMed ↗

Cardiac MRI-based strain analysis for the assessment of left atrial dysfunction in patients with atrial fibrillation.

This retrospective study evaluated whether cardiac magnetic resonance feature tracking (CMR-FT) left atrial (LA) strain parameters can detect early LA dysfunction in atrial fibrillation (AF). Among 113 AF patients and 52 matched healthy controls, LA strain metrics (including εs, εe, and εa) and structural/functional measures (e.g., LAEF, LAD, LAVI) were compared, and AF patients were stratified by abnormal versus normal LAEF/LAVI. The findings indicate that CMR-FT LA strain provides sensitive assessment of LA dysfunction in AF, potentially enabling earlier detection than conventional static measurements.

Zhou H, Zhu D, Hao S et al. · The international journal of cardiovascular imaging · (2026) · View on PubMed ↗ · Free PDF ↗

Enhanced risk stratification in hypertrophic cardiomyopathy through the integration of extracellular volume fraction on cardiovascular magnetic resonance.

This multicenter analysis studied 990 consecutive hypertrophic cardiomyopathy (HCM) patients undergoing cardiovascular magnetic resonance (CMR) from 2012–2024, quantifying late gadolinium enhancement (LGE) and global extracellular volume fraction (ECV). The key finding was that adding CMR-derived ECV (a diffuse interstitial fibrosis marker) provided incremental prognostic value beyond LGE for HCM-related events, including sudden cardiac death (SCD), heart failure (HF), and HCM-related death. Clinically, integrating ECV into CMR risk stratification could improve identification of HCM patients at higher risk for adverse outcomes.

Lee HJ, Gwak SY, Lee S et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗

Entropy for Prediction of MACEs in Myocarditis: A Cardiac MRI-based Biomarker of Myocardial Tissue Heterogeneity.

This retrospective multicenter study evaluated whether left ventricular (LV) entropy measures derived from cardiac MRI—global entropy and late gadolinium enhancement (LGE) entropy—in 492 patients with acute myocarditis (discovery cohort n=319; external testing cohort n=173) predict major adverse cardiovascular events (MACEs). LV global entropy and LV LGE entropy were associated with cardiovascular events, indicating that myocardial tissue heterogeneity quantified by MRI entropy improves risk stratification beyond conventional imaging features. Scientifically and clinically, the findings suggest LV entropy as a quantitative cardiac MRI biomarker for prognosis in acute myocarditis, potentially enabling earlier identification of patients at higher risk for MACEs.

Wang Y, Li L, Teng F et al. · Radiology · (2026) · View on PubMed ↗

A Comparison of Tissue Property Values Estimated Using Conventional Cardiac MRF and MT-Cardiac MRF.

This work compared tissue property values estimated using conventional cardiac magnetic resonance fingerprinting (cMRF) versus MT-cardiac MRF that explicitly models magnetization transfer (MT) during reconstruction to quantify T1 and T2. The key finding was that incorporating MT modeling improved the accuracy/robustness of estimated free-water and bound-pool parameters (e.g., T1f, T2f, and bound pool fraction) compared with a dictionary that ignores MT processes, supported by simulations, phantom experiments, and measurements in 14 healthy subjects. Scientifically, this advances quantitative cardiac MRI by reducing bias from MT effects, which can improve tissue characterization in clinical studies.

Kaplan S, Liu Z, Hamilton J et al. · Magnetic resonance in medicine · (2026) · View on PubMed ↗ · Free PDF ↗

The importance of spatial resolution in detecting chronic myocardial iron remnants following hemorrhagic myocardial infarction with T2* MRI.

This study investigated how spatial resolution affects detection of chronic myocardial iron remnants after hemorrhagic myocardial infarction (hMI) using T2* cardiac MRI, combining digital phantom simulations and ex-vivo swine hearts (n=10) with 8-week hMI. Lower in-plane voxel sizes and slice thickness influenced iron-deposit detectability across multiple signal-to-noise ratio levels, demonstrating that spatial resolution materially changes performance. Scientifically, it provides imaging-physics guidance for optimizing T2* MRI acquisition to reliably quantify chronic hemorrhage-related iron.

Zhang X, Yang HJ, Dharmakumar R · Biomedical physics & engineering express · (2026) · View on PubMed ↗ · Free PDF ↗

Cardiac MRI Identifies Subclinical Myocardial Tissue Abnormalities in Individuals With Hepatitis C Regardless of Myocardial Damage Markers or Fibrosis Stage.

This 3T cardiac MRI study assessed extracellular volume (ECV) fraction as a marker of inflammation/fibrosis in 10 untreated individuals with chronic hepatitis C virus (HCV) infection prior to therapy and compared them with age-matched healthy volunteers. HCV-infected participants had significantly higher ECV fraction (0.30±0.03 vs 0.26±0.03) regardless of myocardial damage markers, hypertension, smoking pack-years, or fibrosis stage. The results suggest early extrahepatic cardiac involvement in HCV before overt fibrosis or myocardial injury, supporting prompt HCV treatment.

D’Amore A, Sirajuddin A, George N et al. · Journal of viral hepatitis · (2026) · View on PubMed ↗

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Cardiomyopathies & inherited/genetic heart disease (including genotype–phenotype divergence)

Left ventricular excessive trabeculation: pathophysiology, diagnostic challenges, and prognostic significance.

This narrative review examined left ventricular excessive trabeculation (LVET)—including its relationship to left ventricular non-compaction (LVNC)—by focusing on pathophysiology, diagnostic challenges, and prognostic implications across genetic and acquired etiologies. The key finding was that LVET should be viewed as a heterogeneous phenotypic trait influenced by genetic factors, embryologic developmental processes, and hemodynamic adaptations, rather than a single primary cardiomyopathy mechanism. This matters scientifically and clinically because it explains why diagnosis and prognosis vary and why imaging criteria and risk assessment should account for underlying causes.

Beltrami M, Maestrini V, Baritussio A et al. · Heart failure reviews · (2026) · View on PubMed ↗

Clinical Course and Predictors of Heart Failure in Asymptomatic Obstructive Hypertrophic Cardiomyopathy.

This retrospective multicenter study evaluated predictors of progression to symptomatic heart failure in 341 asymptomatic patients with obstructive hypertrophic cardiomyopathy (NYHA class I, LVEF >50%, LV outflow tract gradient ≥30 mmHg) followed across four centers from 2003–2023. The key finding was that specific baseline clinical and echocardiographic features (in the context of obstructive physiology) were associated with subsequent development of symptomatic heart failure, identifying risk factors for deterioration in this otherwise asymptomatic population. This is significant because it can refine monitoring and early intervention strategies for patients with obstructive hypertrophic cardiomyopathy before they develop overt heart failure.

Schulz A, Maron MS, Peng LW et al. · Journal of the American Heart Association · (2026) · View on PubMed ↗ · Free PDF ↗

VCAM-1 as a biomarker of early cardiac phenotypic changes in Fabry disease.

This exploratory cross-sectional study assessed whether vascular cell adhesion molecule-1 (VCAM-1), an endothelial activation biomarker, reflects early cardiac phenotypic changes in Fabry disease (FD) adults. In 14 genetically confirmed FD adults from a family carrying the GLA p.Arg363His variant and 30 matched healthy controls, VCAM-1 levels were evaluated for association with early cardiac changes. If VCAM-1 tracks early cardiac involvement, it could support earlier risk stratification and monitoring in FD using a minimally invasive biomarker.

Lino DODC, Meneses GC, de Almeida IM et al. · BMC cardiovascular disorders · (2026) · View on PubMed ↗ · Free PDF ↗

Atypical Case of Takayasu Aortitis Presenting as Embolic Stroke With Concomitant Massive Thoracic Artery Aneurysm.

This case report described a 44-year-old woman with Takayasu aortitis presenting as embolic stroke with a concomitant massive thoracic artery aneurysm. The key finding was that surgical pathology showed granulomatous inflammation consistent with an autoimmune or infectious etiology, and the patient underwent open repair with a Dacron graft. Clinically, it highlights that Takayasu aortitis can manifest with embolic neurologic events and large aneurysms, requiring prompt vascular and pathologic evaluation.

Henson JC, Myers JH, Cummins M et al. · Clinical case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Stress native mapping does not distinguish patients with previous myocardial infarction with non-obstructive coronary arteries from healthy volunteers.

This study compared 1.5T CMR native T1 and native T2 stress perfusion mapping (with adenosine stress) between patients with prior suspected MINOCA who had normal CMR (n=15) and age- and sex-matched healthy volunteers. Stress native T1 and T2 (and related quantitative perfusion mapping) did not distinguish MINOCA patients with normal CMR from healthy controls. These findings suggest that non-contrast adenosine stress native T1/T2 mapping may have limited diagnostic discrimination for MINOCA patients when standard CMR is normal, informing how microvascular dysfunction is assessed in this subgroup.

Andersson DF, Johansson RS, Tornvall P et al. · Clinical physiology and functional imaging · (2026) · View on PubMed ↗ · Free PDF ↗

Pathological Q Waves in a Young Patient Without Ischemic Heart Disease.

This JACC Case Reports article described an 18-year-old asymptomatic man with pathological septal Q waves on ECG but without ischemic heart disease. The key finding was that multimodality cardiac imaging—particularly cardiac MRI for tissue characterization—was central to differential diagnosis and risk assessment in this atypical ECG presentation. Clinically, it highlights that pathological Q waves in young patients require imaging-based evaluation to identify non-ischemic causes and guide management.

Figueroa-Galván FS, Alanís-Naranjo JM, González-Najera MF et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Apical Hypertrophic Cardiomyopathy in ATTR Val142Ile Carrier: When Genes and Phenotype Diverge.

This case report described a 61-year-old African-American man with longstanding apical hypertrophic cardiomyopathy (ApHCM) who carried the pathogenic transthyretin (TTR) variant Val142Ile (ATTR V142I). The key finding was that despite genotype positivity, technetium-99m pyrophosphate scintigraphy (H/CL 1.01, visual grade 0) excluded transthyretin cardiac amyloidosis cardiomyopathy, and cardiac MRI confirmed apical-predominant hypertrophy with patchy LGE consistent with ApHCM. This is significant because it demonstrates genotype–phenotype divergence and the need for imaging confirmation to avoid misdiagnosis and inappropriate ATTR-CM management.

Khayat O, Moumneh MB, Salman O et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Filamin C Genetic Cardiomyopathy Presenting as Acute Myocardial Injury.

This case report studied acute myocardial injury in a 46-year-old man with nonischemic cardiac MRI findings and subsequently identified a pathogenic FLNC (filamin C) gene variant. Cardiac magnetic resonance imaging showed extensive ring-like subepicardial late gadolinium enhancement across 10 left ventricular segments without myocardial edema, with follow-up at 4 months demonstrating persistent fibrosis but preserved ventricular function and no arrhythmias. The report highlights that FLNC-related genetic cardiomyopathy can present as acute myocardial injury with a distinctive ring-like LGE pattern, supporting early genetic evaluation when nonischemic injury patterns are seen.

Alexandrino FB, Curtis B, Nguyen C et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Discordant Cardiomyopathy Phenotypes in Siblings With Homozygous FKRP c.1100T>C.

This case report studied two South African Afrikaner siblings with homozygous FKRP c.1100T>C (p.Ile367Thr) to examine how the same genotype can yield discordant cardiac phenotypes. The brother developed progressive nondilated cardiomyopathy (LVEF 41% at age 17) that evolved into dilated cardiomyopathy with extensive late gadolinium enhancement over 7 years, whereas the sister had a different cardiac phenotype (details truncated in the abstract). The findings emphasize that even with a shared homozygous FKRP founder variant, cardiac involvement can vary substantially, informing risk stratification and surveillance strategies in FKRP-related limb-girdle muscular dystrophy.

Mahon N, Coad S, Kiamanesh O · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗

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Arrhythmias & sudden cardiac death risk (including ablation substrate and PVCs)

Arrhythmic Myocarditis and Prevention of Sudden Cardiac Death: Current Evidence, Risk Stratification, and Management.

This review synthesized evidence on arrhythmic myocarditis and how to stratify risk for sudden cardiac death (SCD), focusing on clinical presentation, ventricular arrhythmia burden, ventricular function, genetic variants, and cardiac magnetic resonance (CMR) findings such as late gadolinium enhancement (LGE). The key finding was that ventricular arrhythmias occur in roughly 10% of hospitalized acute myocarditis patients—often early in the inflammatory phase—and that effective SCD risk stratification requires integrating arrhythmic, functional, genetic, and CMR substrate information rather than relying on a single factor. This is clinically significant because it supports more precise management decisions (monitoring intensity and preventive strategies) for patients with myocarditis who present with or develop arrhythmic phenotypes.

Imazio M, Collini V, Tomat M et al. · Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese · (2026) · View on PubMed ↗

Identifying the Presence and Characteristics of Mid-Myocardial and Epicardial Fibrosis From Intracardiac Electrograms in Patients Undergoing Ventricular Arrhythmia Ablation Using a Transformer-Based Self-Supervised Classifier.

This study investigated whether intracardiac electrograms recorded during ventricular arrhythmia ablation can be used to detect and characterize mid-myocardial and epicardial fibrosis, using a transformer-based self-supervised machine-learning classifier in patients undergoing ventricular arrhythmia ablation. The key finding was that the transformer-based self-supervised approach could infer nonendocardial scar characteristics from electrogram data, addressing limitations of delayed-enhancement CMR (e.g., workflow/artifact barriers in patients with implantable devices). This is significant because it could enable more accurate intra-procedural substrate identification and potentially improve ablation success for ventricular arrhythmias.

Liu X, Qayyum A, Bandyopadhyay S et al. · Circulation. Arrhythmia and electrophysiology · (2026) · View on PubMed ↗

Multiomics Insights Into the Role of Spondin-1 in the Pathogenesis and Prognosis of Atrial Fibrillation.

This study used integrative multiomics—Mendelian randomization and colocalization of plasma protein quantitative trait loci (pQTL) and atrial expression quantitative trait loci (eQTL) with atrial fibrillation (AF) genome-wide association studies—to identify molecular drivers of AF, then prioritized SPON1 (spondin-1) for deeper characterization using single-nucleus RNA sequencing and spatial transcriptomics. SPON1 emerged as a priority candidate with supporting genetic and tissue-level evidence linking it to AF pathogenesis and prognosis. These findings nominate SPON1 as a potential biomarker and therapeutic target for AF and provide a multi-omics framework to uncover causal protein–gene mechanisms in atrial remodeling.

Long X, Zhang Y, Gao X et al. · Journal of the American Heart Association · (2026) · View on PubMed ↗ · Free PDF ↗

Targeting Arrhythmogenic Late Sodium Current by FHF1A-Derivative FixR in Heart Failure Cardiomyocytes.

This study investigated whether an engineered peptide inhibitor, FixR (FHF inhibiting x region), can target the arrhythmogenic late sodium current (INa,L) in heart failure (HF) cardiomyocytes, focusing on FHF1A-related regulation of INa,L. Using reverse-transcriptase quantitative PCR of cardiac sodium channel and FHF splice isoforms in human HFrEF and HFpEF models, the authors tested FixR’s effects on INa,L and related proarrhythmic phenotypes. The results support FHF1A-pathway modulation as a potential therapeutic strategy to reduce late Na+ current–driven arrhythmia risk in HF.

Hegyi B, Angsutararux P, Chakouri N et al. · Circulation research · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗

Improving arrhythmic risk prediction using cardiac magnetic resonance within deep learning in ischemic heart disease.

This study assessed whether deep learning models using cardiac magnetic resonance (CMR) improve arrhythmic risk prediction in ischemic heart disease (IHD) beyond conventional clinical markers. In two independent IHD cohorts (including REVIVED-BCIS2-derived Dataset 2), late gadolinium enhancement (LGE) CMR features were used within deep learning to better stratify patients for arrhythmic events. The work suggests that automated scar-burden/heterogeneity information from LGE-CMR can enhance sudden arrhythmic death risk prediction for clinical decision-making.

Sen A, Jones RE, Morgan H et al. · NPJ cardiovascular health · (2026) · View on PubMed ↗ · Free PDF ↗

Revisiting the Link Between Substrate and Ventricular Tachycardia Rate: The Critical Role of Conduction Isthmus Structure and Function.

This prospective cohort study examined how global scar substrate metrics versus local conduction-isthmus structure and function predict ventricular tachycardia (VT) rate in 62 patients undergoing ablation for scar-related VT. It found that isthmus-specific conduction properties provided more direct predictive insight into VT rate than purely global substrate measures. The significance is that mapping and targeting conduction isthmus features may improve risk stratification and ablation strategy for VT by better linking local electrophysiology to clinical VT dynamics.

Guichard JB, Castrillo-Golvano L, Molero-Pereira S et al. · Heart rhythm · (2026) · View on PubMed ↗ · Free PDF ↗

Treatment of Premature Ventricular Contractions: A Review of Medical Therapy, Catheter Ablation, and Emerging Treatments.

This review studied the clinical management of premature ventricular contractions (PVCs) in patients with and without structural heart disease, focusing on medical therapy, catheter ablation, and emerging treatments. It found that PVC significance varies with symptom burden, PVC frequency, ventricular function, and underlying myocardial disease, and that PVCs can contribute to PVC-induced cardiomyopathy or trigger malignant ventricular arrhythmias in selected patients. Clinically, the article supports a risk- and phenotype-driven diagnostic workup (ECG, ambulatory monitoring, echocardiography, exercise testing, and cardiac MRI) to guide escalation from antiarrhythmic strategies to catheter ablation when needed.

Elattar S, Hodhod A, Basha NR et al. · Cardiology in review · (2026) · View on PubMed ↗

A Case of Brugada Syndrome… or Something Else? Behind Type 1 Brugada Pattern.

This case report described a 51-year-old man with syncope during a febrile illness who had a transient spontaneous type-1 Brugada ECG pattern, raising concern for Brugada syndrome versus an alternative diagnosis. The key finding was that Holter monitoring revealed multifocal ventricular ectopy including non-sustained ventricular tachycardia (NSVT), prompting reconsideration of the underlying cause when the ECG pattern was transient. This is significant because it emphasizes that a type-1 Brugada pattern—especially when transient—should trigger careful evaluation for structural or alternative arrhythmogenic substrates beyond classic Brugada syndrome.

Scarà A, Borrelli A, Romano S et al. · Clinical case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Assessment of left atrioventricular coupling index in hypertrophic cardiomyopathy: improving risk stratification with cardiac magnetic resonance (CMR).

This retrospective study assessed the prognostic value of the left atrioventricular coupling index (LACI), defined as left atrial end-diastolic volume divided by left ventricular end-diastolic volume, in 2,240 patients with hypertrophic cardiomyopathy using CMR-derived parameters including LGE and LVEF. The key finding was that LACI predicted sudden cardiac death (SCD) events and provided incremental prognostic information beyond guideline-based risk models. This suggests LACI could refine SCD risk stratification in HCM using routinely obtainable CMR volumetric measures.

Zhang D, Qian Y, Gu Z et al. · Clinical radiology · (2026) · View on PubMed ↗

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Myocarditis & inflammatory cardiomyopathies (incl. myocarditis-like phenotypes)

A hidden threat in the apical shadow: a case report regarding Loeffler endocarditis mimicking NSTEMI.

This case report described a 71-year-old man with long-standing idiopathic hyper-eosinophilia who presented with chest pain and progressive dyspnoea and was initially suspected of having NSTEMI. Cardiac MRI showed apical endocardial fibrosis with intracavitary thrombus, confirming Loeffler endocarditis due to hyper-eosinophilic syndrome (HES). The report emphasizes that CMR can distinguish Loeffler endocarditis from acute coronary syndromes, guiding appropriate corticosteroid and vitamin K antagonist anticoagulation rather than standard NSTEMI pathways.

Caruzzo CA, Rigamonti E, Scopigni FR et al. · European heart journal. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Lyme Myopericarditis With Effusive-Constrictive Physiology: Serial CMR Identifies a Reversible Inflammatory Phenotype.

This JACC Case Reports article describes a 45-year-old man with Lyme myopericarditis presenting with effusive-constrictive physiology, evaluated using serial cardiovascular magnetic resonance (CMR). The key finding was that serial CMR demonstrated a reversible inflammatory phenotype, helping distinguish inflammatory constriction from fixed constriction—an important management distinction. The case supports using serial CMR to guide treatment decisions in atypical Lyme pericardial disease with effusive-constrictive features.

Alhirtani N, Bigham G, Fabrizio C et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Prognosis of acute myocarditis beyond hospitalization: Results of a long-term prospective study.

This prospective single-center cohort study followed 158 patients admitted with acute myocarditis (AM) between 2007 and 2022 to assess long-term prognosis beyond hospitalization. The key finding was that severe complications such as cardiogenic shock or arrhythmic storm occurred in 3.6% of patients, with follow-up including annual clinical assessment plus treadmill testing, Holter monitoring, and echocardiography (and additional outcomes truncated in the abstract). Clinically, the study provides longer-term risk context for AM survivors and supports structured post-discharge surveillance.

de Freitas Vilela MM, Martins AM, Cazeiro D et al. · Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology · (2026) · View on PubMed ↗ · Free PDF ↗

Myocardial Calcification as a Rare Cardiac Sequela: When Sepsis Leaves Its Mark.

This case report described a 33-year-old woman who developed myocardial calcification after severe sepsis from disseminated Streptococcus pneumoniae, with markedly elevated troponin but normal coronary angiography. The key finding was that repeat chest CT four weeks later showed new extensive left ventricular and papillary muscle calcifications, consistent with sepsis-related myocardial calcification. Scientifically and clinically, it underscores a rare but potentially persistent structural sequela of sepsis that may require follow-up imaging when cardiac injury markers are present.

El-Hamad A, Sene PM, El Mehdi El Yamani M et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Septic cardiomyopathy: Fact or fiction?

This narrative review examined septic cardiomyopathy (SCM) as an acute, potentially reversible myocardial dysfunction occurring during sepsis and contrasted it with other acute cardiomyopathies such as Takotsubo cardiomyopathy and myocarditis. The key finding was that SCM remains “fact or fiction” largely because standardized diagnostic criteria are lacking and clinical/imaging overlap is substantial. Scientifically and clinically, it highlights the need for clearer definitions and diagnostic frameworks using echocardiography/strain, biomarkers, and clinical context.

Naimi A, Rodriguez M, Qadeer YK et al. · American heart journal plus : cardiology research and practice · (2026) · View on PubMed ↗ · Free PDF ↗

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Takotsubo syndrome & stress cardiomyopathy phenotyping

Sudden Cardiac Arrest and Takotsubo-Like Cardiomyopathy as the Initial Presentation of Primary Carnitine Deficiency.

This JACC Case Reports article describes an 18-year-old woman who presented with ventricular fibrillation cardiac arrest and was ultimately diagnosed with primary carnitine deficiency (PCD). Genetic testing identified a homozygous pathogenic SLC22A5 variant (c.43G>T; p.Gly15Trp) consistent with autosomal recessive PCD, with cardiac magnetic resonance showing a Takotsubo-like cardiomyopathy phenotype. The report highlights that PCD can present with sudden cardiac arrest and stress cardiomyopathy-like imaging, supporting early genetic diagnosis and timely carnitine-cycle targeted treatment.

Talasani N, Przybylski R, Delaney MA et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗

CMR Reveals the Influence of Trigger and Classification on the Myocardial Tissue Response in Takotsubo Syndrome.

This CMR study investigated how trigger type and the InterTAK classification relate to myocardial tissue response in patients with Takotsubo syndrome (TTS), comparing left ventricular function, myocardial edema, and myocardial injury across InterTAK categories and between primary versus secondary TTS. The key finding was that CMR-detected tissue responses varied according to trigger/classification, supporting biologic differences between primary (emotionally primed) and secondary (direct myocardial injury–driven) TTS. This is clinically important because it suggests CMR phenotyping could refine understanding of TTS mechanisms and potentially inform prognosis and management.

Gotschy A, Cammann VL, Schweiger V et al. · Circulation. Cardiovascular imaging · (2026) · View on PubMed ↗

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Ischemic heart disease, MINOCA/MINOCA-like syndromes & myocardial injury mechanisms

Prevalence and prognostic impact of unrecognized myocardial infarction detected by cardiac magnetic resonance in Thai patients with obesity.

This cohort study evaluated the prevalence and prognostic impact of cardiac magnetic resonance (CMR)-detected unrecognized myocardial infarction (UMI) in 1,053 Thai adults with obesity (BMI ≥25 kg/m2) without prior MI or coronary revascularization. CMR identified UMI and the presence of CMR-detected UMI was associated with worse clinical outcomes during follow-up. These findings support using CMR to uncover silent myocardial injury in Asian patients with obesity to improve cardiovascular risk stratification and prevention.

Chayanopparat P, Siriphiphatcharoen P, Laohabut I et al. · PloS one · (2026) · View on PubMed ↗ · Free PDF ↗

Molecular mechanisms of coronary microembolization-induced MINOCA.

This basic research article examined the molecular mechanisms by which coronary microembolization (CME) can cause myocardial infarction with non-obstructive coronary arteries (MINOCA). It frames CME as a major underlying pathology for MINOCA and highlights that delayed cardiac MRI diagnosis (often performed days after the event) limits rapid therapy initiation. Scientifically, the review identifies gaps in understanding CME’s molecular drivers, motivating development of faster diagnostic tools and CME-targeted treatments for MINOCA.

Iske J, Thau H, Mesfin JM et al. · Basic research in cardiology · (2026) · View on PubMed ↗ · Free PDF ↗

Stratified Medicine with Eplerenone for Myocardial Infarction or Injury and No obstructive Coronary Arteries: A Registry-Based Basket Trial.

This registry-based basket trial studied stratified medicine in patients with myocardial infarction with no obstructive coronary arteries (MINOCA) or nonischemic myocardial injury, focusing on coronary microvascular dysfunction endotypes and treatment with eplerenone. It found that the study design and objectives enable assessment of the prevalence and prognostic implications of coronary microvascular dysfunction and then evaluation of eplerenone in patients with that endotype. Scientifically, it addresses a major evidence gap by testing an endotype-informed approach to therapy in MINOCA/MINOCA-like syndromes where evidence-based treatments are limited.

Sykes R, Tan D, McKinley G et al. · American heart journal · (2026) · View on PubMed ↗ · Free PDF ↗

Right ventricular thrombus following a left anterior descending infarction: a rare case report of a common culprit.

This case report studied a 39-year-old man who developed a rare right ventricular (RV) thrombus after an anterior ST-elevation myocardial infarction (STEMI) due to a thrombotic occlusion of the mid-left anterior descending (LAD) artery in a left-dominant coronary system. The key finding was that advanced cardiac imaging supported the diagnosis of RV thrombus in an atypical infarct-extension pattern following an anterior LAD infarction. The clinical significance is that clinicians should consider RV thrombus even after anterior STEMI, and use advanced imaging to avoid missed diagnosis and to guide appropriate management.

Bigvava T, Hoechli A, Anabitarte P et al. · European heart journal. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗

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Coronary imaging, perfusion/viability & ischemia testing interpretation

Viability testing for guiding revascularization in ischemic cardiomyopathy.

This review assessed the role of myocardial viability testing in guiding revascularization decisions for ischemic cardiomyopathy, focusing on evidence from major trials (including STICH and follow-up) and how contemporary guideline-directed medical therapy changes the decision landscape. The key finding was that survival benefit from coronary artery bypass grafting (CABG) can occur independently of viability status, challenging the traditional assumption that viability testing reliably predicts functional recovery and improved outcomes after revascularization. This is clinically significant because it informs how clinicians should weigh viability testing versus modern revascularization strategies and medical therapy when selecting patients for CABG or other interventions.

Li KY, Dhingra NK, Patel R et al. · Current opinion in cardiology · (2026) · View on PubMed ↗

Cost-effectiveness of imaging modalities in coronary heart disease: A comprehensive review.

This comprehensive review evaluated the cost-effectiveness of coronary heart disease imaging modalities, with emphasis on myocardial perfusion imaging (MPI) using SPECT and PET. The key finding is that economic evaluations increasingly need to account for rising healthcare costs and rapidly evolving nuclear cardiology technologies when selecting between SPECT and PET-based strategies. The review is significant for guiding payer- and clinician-level decisions on which imaging approach provides the best value for CHD diagnosis and management.

Milan E, Giubbini R, Vitola J et al. · Seminars in nuclear medicine · (2026) · View on PubMed ↗

Characteristics and outcomes of patients undergoing coronary computed tomography angiography for suspected acute coronary syndrome in the emergency department.

This retrospective study evaluated 198 ED patients with suspected acute coronary syndrome who underwent cardiology assessment and coronary computed tomography angiography (CCTA) between January 2020 and December 2022. The key finding was the observed rate of the primary composite endpoint of major adverse cardiovascular events (MACE)—all-cause death, acute myocardial infarction, or myocardial revascularization—among those referred for CCTA (with results reported as 175 patients and truncated further details in the abstract). These findings inform how CCTA-based pathways perform for risk/outcome assessment in real-world ED presentations of suspected ACS.

Ciliberti G, Compagnucci P, Finori L et al. · The international journal of cardiovascular imaging · (2026) · View on PubMed ↗

Variability in Cardiac Stress Test Interpretation: Agreement Between Enrollment Sites and Core Laboratories in the Global ISCHEMIA Trial.

This study evaluated variability in myocardial ischemia interpretation between enrollment sites and core laboratories in patients with chronic coronary disease enrolled in the global ISCHEMIA trial (37 countries, 2012–2018). The key finding was that stress-test ischemia interpretation showed measurable disagreement across sites versus core laboratories, indicating nontrivial variability in how ischemia was classified. This matters because inconsistent stress-test reading can affect trial eligibility, risk stratification, and the generalizability of ischemia-guided management strategies.

O’Keefe E, Sperry BW, Jones PG et al. · Circulation. Population health and outcomes · (2026) · View on PubMed ↗ · Free PDF ↗

Comparison of Cardiac MR with PET CT in Evaluation of Myocardial Viability: Single-Center Experience.

This prospective single-center study compared cardiac MRI parameters (end-diastolic wall thickness, regional wall motion abnormalities, and late gadolinium enhancement) against PET-CT in 28 adults with perfusion/metabolism matched or mismatched defects. MRI-derived EDWT measured manually and with semiautomatic software was evaluated for myocardial viability relative to PET-CT findings, with infarcted tissue assessed using LGE. The work supports refining cardiac MRI protocols for viability assessment when PET-CT is used as the reference standard.

Arafath MY, Debi U, Singhal M et al. · The Indian journal of radiology & imaging · (2026) · View on PubMed ↗ · Free PDF ↗

Diagnosis of cardiac pathology on acute electrocardiographic-gated thoracic computed tomography: guidance for the general radiologist.

This article provided guidance for general radiologists on diagnosing cardiac pathology on acute electrocardiographic-gated thoracic CT angiography, emphasizing that the same dataset used for acute aortic syndrome can reveal other cardiac causes. The key finding was a practical framework to reduce missed or misinterpreted life-threatening cardiac pathology, including coronary artery atheromatous disease and related complications. This is significant for improving diagnostic accuracy and patient safety when radiologists interpret ECG-gated thoracic CT in acute presentations.

Manghat NE, Greco F, Harries I et al. · Clinical radiology · (2026) · View on PubMed ↗

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Cardiac sarcoidosis imaging & biopsy/tissue diagnosis frameworks

Multidisciplinary approach in cardiac sarcoidosis: to biopsy or not?

This review studied the diagnostic role of endomyocardial biopsy (EMB) in patients with cardiac sarcoidosis, focusing on how it fits within a multidisciplinary framework alongside noninvasive imaging. It found that EMB’s historically “gold standard” status is increasingly challenged by limited sensitivity, false-negative/inconclusive results, and procedural risks, leading to greater reliance on modern imaging strategies. Clinically, the review supports a more selective, imaging-driven approach to tissue diagnosis in cardiac sarcoidosis rather than routine EMB for all patients.

Pericao A, Sharma R · Current opinion in pulmonary medicine · (2026) · View on PubMed ↗

FDG PET for cardiac sarcoidosis: Protocol optimization, quantification, pitfalls, and multimodality imaging integration.

This review studied how to optimize and interpret 18F-FDG PET for cardiac sarcoidosis, focusing on protocol design, quantification approaches, common pitfalls, and integration with multimodality imaging (echocardiography and cardiac MRI). It concludes that PET should be used within a probabilistic multimodality framework and details how dietary preparation and imaging/analysis choices affect diagnostic performance and interpretation. The review is clinically significant because it provides practical guidance to improve diagnostic accuracy and management decisions for cardiac sarcoidosis, where outcomes include heart failure, conduction disease, ventricular arrhythmias, and sudden cardiac death.

Wopperer SB, Kronzer E, Ivare J et al. · Seminars in nuclear medicine · (2026) · 1 citations · View on PubMed ↗

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Amyloidosis (AL/TTR) imaging, strain, and risk stratification

Incremental Prognostic Value of Cardiac Magnetic Resonance Beyond Biomarker Staging in Transthyretin Cardiac Amyloidosis.

This multicenter retrospective cohort study evaluated whether adding cardiac magnetic resonance (CMR) parameters improves prognostic prediction beyond biomarker-based National Amyloidosis Center (NAC) staging in 266 patients with transthyretin cardiac amyloidosis (ATTR-CA). The key finding was that CMR variables provided incremental prognostic value for time to death over the NAC stage model, and the combined approach could better identify patients needing evaluation for advanced heart failure therapies and emerging disease-modifying treatments. This is significant because it supports integrating CMR into ATTR-CA risk stratification to refine clinical decision-making beyond serum biomarker staging alone.

Chiou T, Minga I, Subashchandran V et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗

Extracellular Volume Mapping by Cardiac MRI Predicts Sudden Cardiac Death in AL Amyloidosis: A South Asian Cohort Study.

In a South Asian ambispective cohort of 188 patients with biopsy-proven AL amyloidosis, the study measured cardiac extracellular volume (ECV) at diagnosis using T1 mapping on cardiac MRI and assessed its association with sudden cardiac death. Among the subset with evaluable ECV (22 patients), ECV was abnormal (≥25%) in 17 and normal (<25%) in 5, and higher ECV predicted sudden cardiac death risk. This supports ECV mapping as a clinically actionable biomarker for risk stratification in AL amyloidosis beyond conventional damage markers.

Pattnaik SA, Ahamed H, Gutjahr G et al. · Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · (2026) · View on PubMed ↗ · Free PDF ↗

CTLA4-Ig + Anti-IL-6/IL-6R Treatment Results in Long-term Allograft Survival and Function in Highly HLA-sensitized Patients.

This transplant study evaluated long-term allograft survival and function in highly HLA-sensitized patients using a combined immunosuppressive strategy of CTLA4-Ig plus anti–IL-6/IL-6R. The key finding was that this regimen enabled durable graft outcomes while addressing the heightened rejection risk in highly HLA-sensitized recipients, including those with limited options due to calcineurin inhibitor (CNI) neuro/nephrotoxicity. Clinically, it provides evidence for a CNI-sparing approach that may reduce donor-specific antibody rebound and rejection in this difficult-to-treat population.

Jordan SC, Chandran S, Ammerman N et al. · Transplantation direct · (2026) · View on PubMed ↗ · Free PDF ↗

The Diagnostic and Prognostic Value of Multi-Chamber Strain Analysis by Cardiac MRI in Amyloidosis.

This retrospective study evaluated diagnostic and prognostic value of multi-chamber myocardial strain on cardiac MRI in 47 patients with cardiac amyloidosis, relating strain to native T1 mapping and late gadolinium enhancement (LGE) using QALE. The key finding was that strain parameters across ventricles and atria correlated with native T1 and LGE measures and provided prognostic information for major adverse cardiovascular events (MACE). This supports multi-chamber strain as an imaging biomarker that may improve risk stratification in amyloidosis beyond conventional mapping and LGE alone.

Chilkuri SK, Dsouza R, Houbois C et al. · Journal of thoracic imaging · (2026) · View on PubMed ↗

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Valvular heart disease & structural interventions (including mitral/tricuspid/pulmonary valve planning)

Trileaflet mitral valve in hypertrophic obstructive cardiomyopathy: A rare anatomical variant requiring surgical intervention.

This case report describes a 68-year-old woman with hypertrophic obstructive cardiomyopathy (HOCM) who had a rare trileaflet mitral valve anatomical variant requiring surgery. Multimodal imaging (cardiac magnetic resonance and echocardiography) showed asymmetric septal hypertrophy with left ventricular outflow tract obstruction (resting gradient up to 87 mmHg) and severe mitral regurgitation with systolic anterior motion, with abnormal valve anatomy including anterior leaflet restriction and a clefted posterior leaflet. The key clinical finding was that symptoms persisted despite beta-blockers, leading to surgical intervention on symptomatic and prognostic grounds.

Kumar UA, Sitaranjan DR, Taghavi FJ · Perfusion · (2026) · View on PubMed ↗

An integrative approach to patient selection for mitral transcatheter edge-to-edge repair in secondary mitral regurgitation.

This review studied patient selection for mitral transcatheter edge-to-edge repair (M-TEER) in patients with secondary mitral regurgitation (SMR), integrating evidence from randomized trials (including MITRA-FR and COAPT) and multimodality echocardiography. It found that divergent trial outcomes are largely explained by differences in echocardiographic selection and left-ventricular remodeling, implying that SMR severity should be interpreted relative to ventricular size and regurgitant context. Scientifically and clinically, it proposes a structured framework to identify patients most likely to benefit from M-TEER despite heterogeneity in SMR and heart failure phenotype.

Brusosa M, Flores-Umanzor E, Horlick E · Current opinion in cardiology · (2026) · View on PubMed ↗

One Anatomy, Multiple Valve Choices: Interobserver Agreement in Selecting Transcatheter Pulmonary Valve.

This study evaluated interobserver agreement (IOA) in selecting transcatheter pulmonary valve (TPVR) device type, size, and position using 3D patient-specific anatomies derived from cardiac magnetic resonance images. The key finding was that agreement among six experienced observers varied across valve type (self-expanding, balloon-expandable, or surgical approach), size, and position when planning TPVR using the same 3D reconstructions. Scientifically and clinically, the work highlights where variability in imaging-based planning persists and supports developing a structured framework to improve consistency in TPVR device selection.

Pérez-Cualtán CE, Cabrales J, Garay F et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · (2026) · View on PubMed ↗ · Free PDF ↗

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Congenital heart disease & post-repair hemodynamics (incl. RVOT flow)

Characteristic flow of different right ventricular outflow tract morphology in repaired tetralogy of fallot patients studied by 4D-flow cardiac magnetic resonance images.

This retrospective CMR study analyzed 120 repaired tetralogy of Fallot (rTOF) patients using 4D-flow cardiac magnetic resonance to characterize right ventricular outflow tract (RVOT) flow patterns by morphology. RVOTs were classified as tubular, pyramidal, or trapezoid, and detailed flow characterization focused on tubular (n=86) versus pyramidal (n=22) morphologies due to small minor groups. The results are relevant for predicting hemodynamics and informing suitability for transcatheter pulmonic valve implantation (PPVI) planning in rTOF patients.

Srivichean A, Chungsomprasong P, Sanwong Y et al. · BMC medical imaging · (2026) · View on PubMed ↗ · Free PDF ↗

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Cardiac surgery & perioperative strategies (cardioplegia, revascularization, LV unloading)

Left Ventricular Unloading in Anterior ST-Segment Elevation Myocardial Infarction Without Shock: The ST-Segment Elevation Myocardial Infarction Door to Unload Randomized Controlled Trial.

The STEMI-Door to Unload (DTU) randomized controlled trial tested whether mechanical left ventricular (LV) unloading using a transvalvular microaxial flow pump (TV-mAFP), combined with delayed reperfusion, reduces infarct size versus reperfusion alone in patients with anterior ST-segment elevation myocardial infarction (STEMI) without cardiogenic shock. The key finding was that the LV unloading strategy was evaluated for its ability to decrease infarct size, addressing the load-dependent determinants of myocardial injury in this clinical population. If effective, this approach could change reperfusion workflows in anterior STEMI by incorporating device-based LV unloading to mitigate infarct size and downstream heart failure risk.

Kapur NK, Mangner N, Aghili N et al. · Journal of the American College of Cardiology · (2026) · 5 citations · View on PubMed ↗

Learning curves in Versius-assisted colorectal surgery: a risk-adjusted CUSUM analysis from a single center.

This retrospective single-center study evaluated learning curves for Versius-assisted colorectal cancer surgery using risk-adjusted cumulative sum (RA-CUSUM) analysis. The key finding was procedure- and operator-specific learning trajectories for skin-to-skin operative time across right hemicolectomy (RHC), sigmoid resection (SR), and anterior rectal resection (AR) in adult patients undergoing elective robotic surgery with the Versius system from December 2022 to August 2025. Scientifically, RA-CUSUM learning-curve modeling can help benchmark training and optimize safe adoption of the Versius platform in colorectal surgery.

Sachańbiński T, Miodoński M, Kropieniewicz J · International journal of colorectal disease · (2026) · View on PubMed ↗ · Free PDF ↗

Cardiac Imaging Predictors of Ventricular Recovery in Pediatric Patients Undergoing Aortic Valve Intervention for Regurgitation.

This retrospective study investigated which preoperative echocardiogram and cardiac magnetic resonance (CMR) parameters predict postoperative left ventricular (LV) recovery in pediatric and young adult patients (<30 years) undergoing aortic valve surgery for chronic aortic regurgitation (AR). It found that specific baseline imaging markers were associated with LV reverse remodeling after intervention. Clinically, the results aim to refine timing and risk assessment for AR surgery in younger patients where adult-derived surgical thresholds may not accurately predict recovery.

Flerlage EK, Huma LC, Gandhi R et al. · Pediatric cardiology · (2026) · View on PubMed ↗

Cardiac magnetic resonance imaging assessment of Del Nido versus cold blood cardioplegia in patients with low ejection fraction undergoing combined coronary artery bypass graft and mitral valve replacement: Early outcomes.

This prospective single-center study compared Del Nido cardioplegia (DNC) versus conventional cold blood cardioplegia (CBC) in 42 patients with reduced left ventricular ejection fraction (<45%) undergoing combined coronary artery bypass grafting (CABG) and mitral valve replacement (MVR), using cardiac magnetic resonance (CMR) to assess early myocardial functional recovery. The key finding was that CMR-based early functional recovery differed between the two cardioplegia strategies in this low-EF surgical population. This is significant because it provides early imaging-guided evidence that cardioplegia choice may influence myocardial recovery after complex cardiac surgery.

Gode S, Polat M, Eroğlu Polat A et al. · Turk gogus kalp damar cerrahisi dergisi · (2026) · View on PubMed ↗ · Free PDF ↗

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Heart failure & preventive screening/risk models (incl. HFpEF scores, polypills)

Obstructive sleep apnea and rising cerebrovascular disease mortality in the United States, 1999-2020: A retrospective analysis.

This retrospective analysis studied whether obstructive sleep apnea (OSA) is associated with rising cerebrovascular disease mortality in the United States from 1999–2020, stratifying adults with OSA by gender, race, urbanization, and geographic region. The key finding was that cerebrovascular disease mortality trends among adults with OSA increased over the study period, with differences across demographic and geographic strata. This is significant because it strengthens the public-health rationale for OSA screening and risk reduction as part of strategies to curb cerebrovascular mortality.

Zafar F, Jha M, Min S et al. · Sleep & breathing = Schlaf & Atmung · (2026) · View on PubMed ↗

From inflammation to inheritance: rethinking myocarditis as the first signal of desmosomal cardiomyopathy.

This review article rethinks acute myocarditis as a potential first clinical signal of inherited desmosomal cardiomyopathy by integrating evidence from molecular genetics, cardiac magnetic resonance (CMR), and translational pathology. It highlights that desmosomal dysfunction (via pathogenic variants) can produce myocarditis-like presentations, creating overlap between inflammatory myocarditis and inherited cardiomyopathy phenotypes. Clinically, the work argues for earlier genetic consideration in selected myocarditis cases to enable targeted diagnosis, family screening, and management.

AbdelMassih AF, Sankari AC, Mallouka G et al. · The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · (2026) · View on PubMed ↗ · Free PDF ↗

The HFpEF-ABA score predicts adverse cardiac remodelling and incident heart failure: a UK biobank study.

This UK Biobank study validated the HFpEF-ABA score (age, BMI, atrial fibrillation) as a preventive screening tool for incident heart failure and adverse cardiac remodeling in 416,374 community participants without baseline heart failure. Using cardiac magnetic resonance phenotyping alongside long-term outcome prediction, higher HFpEF-ABA scores were associated with greater risk of developing HFpEF-related remodeling and incident heart failure. The findings support using a simple clinical score to identify individuals who may benefit from earlier imaging-based surveillance and preventive strategies.

Shi Q, Gao Y, Chen D et al. · ESC heart failure · (2026) · View on PubMed ↗

Translation, cross-cultural adaptation, and psychometric evaluation of the Arabic version of the University of Wisconsin running injury and recovery index: a reliability and validity study.

This study investigated translation, cross-cultural adaptation, and psychometric performance of the Arabic version of the University of Wisconsin Running Injury and Recovery Index (UWRI-Ar) in Arabic-speaking runners aged 18–45 years with running-related injury. It found that UWRI-Ar demonstrated acceptable reliability and validity with test-retest assessment in a subset of participants who retested after 2–5 days. This is clinically significant because it provides a validated Arabic patient-reported outcome measure to assess running injury status and recovery in Arabic-speaking populations.

Aljohani MMA, Alshehri YS, Shuwayhi AM et al. · BMC sports science, medicine & rehabilitation · (2026) · View on PubMed ↗ · Free PDF ↗

Polypill for heart failure with reduced ejection fraction: the POLY-HF randomized trial.

This open-label randomized POLY-HF trial studied whether a once-daily heart failure with reduced ejection fraction (HFrEF) polypill improves cardiac function in adults with left ventricular ejection fraction ≤40%, enrolling a predominantly underserved population at two centers. It found that the polypill strategy using metoprolol succinate (25/50/100/150 mg), spironolactone 12.5 mg, and empagliflozin 10 mg was feasible to implement and was compared against rapid uptitration of individual guideline-directed medical therapy medications. The trial’s significance lies in testing whether simplified combination therapy can improve outcomes in real-world-like settings where guideline-directed medical therapy uptake is low.

Pandey A, Keshvani N, Rizvi SK et al. · Nature medicine · (2026) · View on PubMed ↗

Strategies for resilient climate in smart cities mediated by Nash equilibrium and autonomous decision-makers.

This paper studied strategies for climate resilience in smart cities by modeling city-level decision-making using Nash equilibrium, autonomous multi-agent systems, and machine learning. It found that integrating these approaches can generate tailored policy decisions for pollution levels and climate warming risk management for each city agent. The significance is that it offers a computational decision framework for global warming mitigation that can adapt to city-specific conditions rather than using one-size-fits-all policies.

Latha CM, Alvarado-Mentado M · Journal of environmental management · (2026) · View on PubMed ↗

A Global Consensus Conference on Surgical Management of Primary Uterovaginal Prolapse and Lower Urinary Tract Dysfunction: Combining Evidence with Expert Opinion.

This global consensus conference studied best-practice surgical management for primary uterovaginal prolapse (U-POP) and associated lower urinary tract dysfunction by combining systematic review evidence with expert opinion. It found that geographically diverse committees using structured MEDLINE/Embase/ClinicalTrials.gov searches (2000–Dec 2025) and consensus methods produced recommendations and identified key unanswered research questions. The significance is that it standardizes decision-making for controversial aspects of U-POP surgery and guides future high-quality research and systematic review efforts.

Gupta A, Grimes CL, Badlani G et al. · International urogynecology journal · (2026) · View on PubMed ↗ · Free PDF ↗

Stroke and its consequences: protocol and pilot data of the observational Berlin Long-term Observation of Vascular Events (BeLOVE) stroke stratum.

This protocol and pilot analysis studied the design and early data of the Berlin Long-term Observation of Vascular Events (BeLOVE) stroke stratum, enrolling adults with acute ischemic stroke, transient ischemic attack (TIA), or non-traumatic intracerebral hemorrhage. The key finding is that BeLOVE is a prospective, longitudinal, hospital-based observational cohort intended to characterize long-term risks for further major adverse cerebro- and cardiovascular events and death (MACE) and to capture cognitive, mental, and patient-reported outcomes. Scientifically, it provides a structured framework to generate evidence on long-term post-stroke outcomes that are currently poorly understood.

Nolte CH, Weber JE, Ahmadi M et al. · BMJ neurology open · (2026) · View on PubMed ↗ · Free PDF ↗

A 12-week Exercise Intervention Among Older Adults With Chronic Coronary Syndrome: Changes and Associations of Movement Behaviors and Cardiovascular Risk Factors.

This 12-week group exercise intervention study enrolled 35 older adults with chronic coronary syndrome (CCS) and measured changes in movement behaviors (via 7-day accelerometry), obesity markers, VO2peak, cardiometabolic risk, and brain-derived neurotrophic factor (BDNF) from baseline to 9 months. The key finding was the pattern of associations between changes in movement behaviors and improvements in VO2peak, cardiometabolic risk, and BDNF over follow-up. Clinically, it supports exercise programs that target daily movement patterns to improve cardiorespiratory fitness and cardiometabolic and neurotrophic health in CCS.

Ullrich A, Bahls M, Voigt L et al. · European journal of sport science · (2026) · View on PubMed ↗ · Free PDF ↗

Continuous Glucose Monitoring and Mortality Risk Among U.S. Veterans Receiving Dialysis With Diabetes.

This cohort study examined whether continuous glucose monitoring (CGM) use versus non-CGM use is associated with mortality among U.S. veterans receiving dialysis who also have diabetes, using linked national VA, US Renal Data System, and Medicare data. The key finding was that CGM use was associated with a survival difference compared with non-CGM use in this dialysis population (direction and magnitude reported in the full article). If confirmed, CGM could improve dysglycemia characterization and potentially outcomes in high-risk patients where traditional glycemic markers are less reliable.

Narasaki Y, Kalantar-Zadeh K, Zisman-Ilani Y et al. · Diabetes care · (2026) · View on PubMed ↗ · Free PDF ↗

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Cardio-oncology & treatment-related cardiotoxicity/survivorship data

Rare Late Cardiac Involvement Following Resected Primary Limb Dedifferentiated Liposarcoma: A Case Report.

This case report described rare late cardiac involvement in a 68-year-old woman with a history of resected primary limb dedifferentiated liposarcoma (DDLPS), presenting with progressive dyspnea and a mediastinal mass with pericardial involvement. Cardiovascular magnetic resonance (CMR) showed malignant features consistent with sarcoma (e.g., heterogeneous enhancement and tissue characteristics), supporting metastatic cardiac disease after prior DDLPS. The report highlights the need for high clinical suspicion and CMR-based evaluation for late cardiac metastasis in DDLPS survivors, which can directly affect diagnosis and management.

Alizadehasl A, Baghyari S, Salimi M · Clinical case reports · (2026) · View on PubMed ↗

Frontiers in Ocular Therapy: Linking Nanoparticles to Patho- Therapeutic Outcomes in Keratitis Treatment.

This article is a narrative review linking nanoparticle-based drug delivery strategies to patho-therapeutic outcomes in keratitis, focusing on how nanotechnology can overcome limitations of conventional antimicrobials such as poor ocular bioavailability and rapid tear clearance. The key finding is that emerging nanoparticle approaches (including improved delivery, targeting, and combination therapies) are positioned to enhance antimicrobial efficacy against bacterial, fungal, and viral keratitis. Scientifically, it consolidates current evidence to guide future formulation and translational research for more effective keratitis treatments.

Tiwari R, G D, Mohan VK et al. · Recent advances in anti-infective drug discovery · (2026) · View on PubMed ↗

Prevention of arterial catheter-related bloodstream infections: current evidence and future directions.

This review synthesized current evidence and future directions for preventing arterial catheter-related bloodstream infections (AC-CRBSI) in patients requiring arterial catheters for hemodynamic monitoring and blood sampling. It found that, unlike central venous catheter data, fewer studies directly evaluate optimal arterial catheter prevention, but insertion and maintenance strategies (e.g., minimizing catheter manipulation and applying best-practice infection control) are valuable. Clinically, the work supports updating and standardizing AC-specific prevention bundles to reduce AC-CRBSI risk in critical care settings.

Donner V, Sadeghi CD, Catho G et al. · Critical care (London, England) · (2026) · View on PubMed ↗ · Free PDF ↗

Fluoropyrimidine Cardiotoxicity: Role of Uridine Triacetate and Pharmacogenomic Insights from a Case of 5-FU-Induced Cardiogenic Shock.

This review discussed fluoropyrimidine cardiotoxicity, focusing on severe presentations including 5-fluorouracil (5-FU)-induced cardiogenic shock, and highlighted the potential role of uridine triacetate along with pharmacogenomic considerations. The key finding is that uridine triacetate and pharmacogenomic insights may help explain or mitigate fluoropyrimidine-induced cardiac injury beyond the classic mechanism of coronary vasospasm. Clinically, the synthesis supports more informed risk assessment and potential targeted management strategies for patients who develop life-threatening cardiotoxicity from 5-FU or capecitabine.

Filomia S, Del Buono MG, Saponara G et al. · Journal of cardiovascular pharmacology · (2026) · View on PubMed ↗

Diagnostic Tests for Stage B Heart Failure.

This Global Burden of Disease 2021–based analysis quantified ovarian cancer (OC) burden attributable to occupational asbestos exposure across Asia from 1990 to 2021. The key finding was the characterization of age-standardized and crude OC attributable deaths and disability-adjusted life years (DALYs) over time in relation to occupational asbestos exposure (with the abstract truncated before specific numeric results). Public-health significance lies in defining the regional temporal burden to support asbestos control policies and targeted prevention strategies.

Dang HNN, Luong TV, Huynh Q et al. · Current cardiology reports · (2026) · View on PubMed ↗ · Free PDF ↗

Integrative network and structural analysis of Pinus derived phytosterols in diabetes associated pathways.

This in silico pharmacology study used an integrative computational workflow to analyze how two Pinus-derived phytosterols, β-sitosterol and 24-nor-cholest-5,22E-dien-3β-ol, interact with diabetes-associated endocrine targets. The key finding was that ESR1, AR, SHBG, and CYP17A1 emerged as central network nodes in pathways related to endocrine resistance based on network pharmacology analysis. These results suggest potential molecular mechanisms for phytosterol effects in diabetes and provide candidate targets for future experimental validation.

Ali PR, Sri GK, Sravanthi G et al. · In silico pharmacology · (2026) · View on PubMed ↗ · Free PDF ↗

Zanubrutinib combined with R-CHOP in previously untreated diffuse large B-cell lymphoma with specific gene alteration: a phase II study.

This phase II study evaluated zanubrutinib (a BTK inhibitor) combined with R-CHOP as first-line therapy in previously untreated diffuse large B-cell lymphoma (DLBCL) patients aged 18–75 years with high-risk molecular alterations (including MYD88, CD79B, NOTCH1, TP53 mutations, or MYC rearrangements). The key finding was that the trial rationale targeted genomically defined BCR-signaling–associated disease features linked to prior BTK inhibitor sensitivity in relapsed settings. Clinically, the study tests whether adding zanubrutinib to standard R-CHOP improves outcomes for patients with specific high-risk gene alterations.

Zhang Q, Jiang S, Wei R et al. · Blood cancer journal · (2026) · View on PubMed ↗ · Free PDF ↗

Updated patient-reported outcomes and the effect of disease progression on health-related quality of life in the PRIMA/ENGOT-OV26/GOG-3012 trial of niraparib first-line maintenance therapy in patients with newly diagnosed advanced ovarian cancer.

This analysis studied updated patient-reported outcomes (PROs) and the effect of disease progression on health-related quality of life in the PRIMA/ENGOT-OV26/GOG-3012 trial, comparing niraparib first-line maintenance versus placebo in newly diagnosed advanced ovarian cancer. The key finding was that longitudinal HRQOL was assessed using EORTC QLQ-C30 and QLQ-OV28, FOSI, and EQ-5D-5L (EQ-VAS), and that disease progression influenced HRQOL trajectories in this randomized setting. Clinically, the results help contextualize the patient experience of niraparib maintenance by linking treatment and progression to quality-of-life outcomes.

Shahin MS, Lorusso D, Backes FJ et al. · Gynecologic oncology · (2026) · View on PubMed ↗

Cardiac Safety Outcomes in Delandistrogene Moxeparvovec Clinical Trials for Duchenne Muscular Dystrophy with Up to 5 Years of Follow-up.

This analysis assessed cardiac safety outcomes of the dystrophin gene transfer therapy delandistrogene moxeparvovec in clinical trials for Duchenne muscular dystrophy (DMD) with up to 5 years of follow-up (Trials 101, 102, ENDEAVOR, and EMBARK; excluding LVEF <40%). The key finding was that cardiac adverse events and echocardiographic measures were systematically tracked over time, with troponin I monitored regularly, supporting an overall characterization of cardiac safety in this population. Clinically, these results inform monitoring expectations and risk assessment for delandistrogene moxeparvovec as it is used in DMD patients over longer follow-up.

Veerapandiyan A, Bourke J, Soslow JH et al. · Cardiology and therapy · (2026) · View on PubMed ↗ · Free PDF ↗

Use of advanced cardiovascular imaging in rheumatic immune-mediated inflammatory diseases.

This retrospective multi-centre quality improvement study examined real-world use of advanced cardiovascular imaging—cardiac magnetic resonance (CMR), CT coronary angiography (CTCA), and positron emission tomography (PET)—in adults with less common/rare rheumatic immune-mediated inflammatory diseases (systemic lupus erythematosus, systemic sclerosis, inflammatory myopathy, vasculitis, or primary Sjögren’s disease) across four UK hospitals (2023–2024). The key finding was that imaging utilization varied in practice across these conditions and hospitals, highlighting heterogeneity in how and when advanced imaging is applied. This is significant because it identifies gaps that can guide future studies and help standardize imaging-based cardiovascular risk evaluation in these rare rheumatic diseases.

Gumber L, Meghji MA, Kakkar V et al. · Rheumatology (Oxford, England) · (2026) · View on PubMed ↗ · Free PDF ↗

CAR-T Cell Therapy Versus Salvage Chemotherapy in Relapsed/Refractory DLBCL: A Systematic Review and Meta-Analysis Integrating Radiologic, Laboratory, and Histopathologic Correlates.

This systematic review and meta-analysis synthesized randomized trials and comparative cohort studies in adults with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) comparing CAR-T cell therapy versus salvage chemotherapy, integrating radiologic, laboratory, and histopathologic correlates. The key finding was the comparative effectiveness of CAR-T relative to salvage chemotherapy across these outcome domains (with pooled estimates reported in the full text). Clinically, the analysis helps guide treatment selection for high-risk molecular features and primary refractory disease where optimal sequencing between CAR-T and chemotherapy remains uncertain.

Elsayed FM, Baban J, Elkholy HY et al. · La Clinica terapeutica · (2026) · View on PubMed ↗

Autologous Stem Cell Transplantation Of HIV-Positive Plasmablastic Lymphoma - Case Series.

This case series evaluated autologous stem cell transplantation (ASCT) as consolidation in HIV-positive patients with plasmablastic lymphoma (PBL) achieving first complete response (CR1) under highly active antiretroviral therapy (HAART). The key finding was that ASCT was feasible with reported safety and efficacy outcomes in this historically high-risk population. Clinically, it provides evidence supporting consideration of intensive consolidation strategies in HIV-associated PBL when viral control and supportive care are optimized.

Giri Raja Pandiyan VM, Perumal Kalaiyarasi J, Govindarajan DD et al. · Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · (2026) · View on PubMed ↗

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Cardiovascular imaging methods & AI/physics/low-field/automation (including workflow, reconstruction, phantoms)

Clinical Feasibility of Free-Breathing Volumetric Comprehensive Tissue Characterization via the Multi-parametric SAVA Technique.

This study evaluated the clinical feasibility of a free-breathing, volumetric multi-parametric SAVA cardiovascular magnetic resonance (3D mSAVA) protocol for comprehensive myocardial tissue characterization in patients, comparing it against conventional T1 mapping, T2 mapping, and phase-sensitive inversion recovery (PSIR) late gadolinium enhancement (LGE). The key finding was that 3D free-breathing mSAVA enabled acquisition of pre-/post-contrast T1, T2, extracellular volume (ECV), and synthesized bright-blood and dark-blood LGE with performance agreement versus standard mapping/LGE techniques sufficient to support routine clinical feasibility. This matters because a single, volumetric, free-breathing CMR workflow could reduce scan burden and improve adoption of parametric myocardial tissue mapping in everyday cardiology practice.

Jiang Y, Si D, Cai Q et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗

Ferumoxytol dose optimization for three-dimensional whole-heart magnetic resonance imaging in patients with congenital heart disease.

This prospective study in 45 pediatric and young patients with congenital heart disease evaluated ferumoxytol dose escalation for 3D whole-heart (WH) CMR at 1.5 T, testing sequential regimens (1 mg/kg→2 mg/kg vs 2 mg/kg→3 mg/kg) and measuring effects on longitudinal relaxation and image quality. The key finding was that increasing ferumoxytol dose improved the physiologic blood-pool nulling inversion time (TI)—a surrogate for post-contrast T1 shortening—while optimizing 3D WH image quality across the dose-escalation steps. This is clinically significant because it provides a practical dose–response framework to improve ferumoxytol-enhanced CMR quality in children and young patients.

Erdem S, Hussain T, El Jerbi A et al. · Pediatric radiology · (2026) · View on PubMed ↗ · Free PDF ↗

Integrative Observational and Genetic Evidence From the UK Biobank Supports Carotid Intima-Media Thickness as a Window Into Cardiac Remodeling.

This UK Biobank observational and genetic association study analyzed 46,102 participants with carotid ultrasound and cardiac magnetic resonance imaging to test whether carotid intima-media thickness (cIMT) reflects early cardiac remodeling and shares genetic architecture with cardiovascular disease. The key finding was that cIMT was phenotypically associated with cardiac remodeling traits and that genetic evidence supported shared genetic influences between cIMT and cardiovascular outcomes/traits. This is significant because it positions cIMT as a noninvasive “window” into early cardiac structural changes and helps connect vascular biomarkers to underlying genetic mechanisms of cardiovascular disease.

Chong SH, Saccoh AF, van Vugt M et al. · Journal of the American Heart Association · (2026) · View on PubMed ↗ · Free PDF ↗

Association between CMR-derived pulmonary artery pulse wave velocity and pulmonary risk factors: the multi-ethnic study of atherosclerosis COPD study.

This prospective multi-ethnic cohort study in participants from the Multi-Ethnic Study of Atherosclerosis COPD (MESA COPD) assessed whether pulmonary artery (PA) pulse wave velocity (PWV)—a marker of pulmonary arterial stiffness—relates to pulmonary risk factors, particularly smoking history, using cardiac magnetic resonance (CMR). Using 2-D phase-contrast flow imaging and semi-automated software to measure PA PWV (main, right, and left PA), the study tested associations between PA stiffness and smoking exposure. The findings are important because they could establish CMR-derived PA PWV as a quantitative biomarker linking pulmonary risk factors to vascular remodeling and future outcomes.

Huurman R, Xie E, Ohyama Y et al. · Magnetic resonance imaging · (2026) · View on PubMed ↗

A Physiologic Left Ventricle Flow Phantom for 4D Flow MRI Applications and CFD Verification.

This engineering study developed a subject-specific, MRI-compatible left ventricle (LV) flow phantom for 4D flow MRI applications and computational fluid dynamics (CFD) verification. The phantom used a PVA-based hydrogel in a closed-loop circulation system with an MRI-safe pump to reproduce healthy end-diastolic and end-systolic LV geometries for robust model validation. This provides a practical platform to reduce in vivo verification limitations (scan time and motion artifacts) and improve the accuracy of cardiac MRI/CFD pipelines.

Wiegand M, Obermeier L, Dillinger H et al. · Annals of biomedical engineering · (2026) · View on PubMed ↗ · Free PDF ↗

Transforming Cardiac Imaging With Artificial Intelligence: Automation, Precision, and Clinical Integration in Echocardiography and Magnetic Resonance Imaging.

This narrative review studied artificial intelligence (AI) applications for cardiac imaging across echocardiography and cardiac magnetic resonance (CMR), synthesizing 22 peer-reviewed studies from 2020–2026. It found that AI can automate echocardiographic image acquisition, chamber and valve segmentation, and left ventricular ejection fraction measurement with accuracy comparable to experienced echocardiographers, while also reducing interobserver variability and analysis time; it also highlighted automated global longitudinal strain for detecting subclinical dysfunction. The clinical significance is that AI-enabled workflows may improve precision and efficiency in routine cardiac imaging and support earlier detection of myocardial disease.

Choker AH · Echocardiography (Mount Kisco, N.Y.) · (2026) · View on PubMed ↗

A case of cardiac lymphangioma: diagnosis suggested by cardiac CT and MRI and successful conservative management.

This case report studied a 78-year-old woman with cardiac lymphangioma, a rare benign tumor, using multimodality imaging for diagnosis and conservative management. The key finding was that cardiac computed tomography (CT) and cardiac magnetic resonance imaging (CMR) identified a characteristic lobulated non-enhancing mass on CT and a multilocular cystic lesion with high T2 signal on CMR consistent with lymphangioma. Clinically, it demonstrates that advanced imaging can establish a diagnosis without standardized protocols and can support successful non-surgical management in this rare condition.

Kurosaka E, Matsuda J, Yanagiya N et al. · Journal of cardiology cases · (2026) · View on PubMed ↗ · Free PDF ↗

Prediction of hypertension and restenosis under guideline-directed management in aortic coarctation: development and validation of machine-learning models.

This development-and-validation machine-learning study evaluated prediction of hypertension and restenosis in patients with aortic coarctation (CoA) under guideline-directed management using routinely collected electronic health records, cardiovascular magnetic resonance (CMR), and follow-up data from 160 individuals (218 visits) in Berlin, Germany. The key finding was that ML models (including CatBoost, XGBoost, random forest, support vector classifiers, and neural networks) can stratify risk for future hypertension and restenosis despite recurrence occurring in up to one-third of patients over time. Scientifically and clinically, the work supports using CMR-informed ML risk prediction to personalize long-term surveillance and management after CoA treatment.

Fierley L, Versnjak J, Gabel G et al. · EClinicalMedicine · (2026) · View on PubMed ↗ · Free PDF ↗

Computational modeling of left ventricular flow using PC-CMR-derived four-dimensional wall motion.

This computational modeling study developed individualized left ventricular (LV) flow simulations by integrating two MRI modalities that quantify four-dimensional wall motion with computational fluid dynamics (CFD). The key finding was that PC-CMR-derived 4D wall motion can drive subject-specific LV hemodynamic models to characterize intracardiac flow without requiring fully coupled fluid-solid modeling. Scientifically, it advances imaging-driven CFD as a pathway toward personalized assessment of LV hemodynamics for cardiac disease research and potential translation.

Peighambari SB, Mukherjee T, Mendiola EA et al. · International journal of engineering science · (2026) · View on PubMed ↗

Leveraging natural language processing artificial intelligence for automated data extraction of ejection fraction and strain from cardiovascular imaging reports.

This retrospective observational study used natural language processing (NLP) to automatically extract ejection fraction (EF) and strain-related cardiac imaging parameters from free-text cardiovascular imaging reports in cancer survivors across echocardiography, nuclear cardiology, and cardiac MRI over 2000–2020. The key finding was that NLP-based automated extraction of EF and related parameters from multi-modality reports was feasible in a large EHR dataset of >4000 patients. This supports scalable, longitudinal extraction of quantitative cardiac function measures for cardio-oncology research and risk modeling using routine clinical documentation.

Brown SA, BagheriMohamadiPour M, Sparapani R et al. · American heart journal plus : cardiology research and practice · (2026) · View on PubMed ↗ · Free PDF ↗

In vivo evidence of blood flow slippage: failure of the no-slip boundary condition assumption.

This study used four-dimensional flow CMR of the descending thoracic aorta in seven healthy adult volunteers combined with Navier–Stokes modeling and data assimilation to test whether the in vivo “no-slip” boundary condition holds. The key finding was evidence of “blood flow slippage,” with near-wall tangential velocities estimated at approximately 30–80% of the measured near-wall values rather than approaching zero as predicted by no-slip. This challenges a foundational assumption in cardiovascular fluid dynamics and may affect how wall shear stress and related hemodynamic biomarkers are computed from imaging.

Jarolímová A, Hron J, Tůma K et al. · American journal of physiology. Heart and circulatory physiology · (2026) · View on PubMed ↗

Sustainable Low-Field Cardiovascular Magnetic Resonance in Changing Healthcare Systems-An Update.

This review/update summarized advances enabling sustainable low-field cardiovascular magnetic resonance (LF-CMR), particularly around 0.55 Tesla, for cardiac structure, function, and tissue characterization in settings with limited resources. The key finding was that optimized hardware (e.g., gradient/RF improvements) and AI-driven reconstruction can preserve strong diagnostic performance despite lower signal-to-noise at low field strengths. This is clinically significant because it supports broader CMR access in low- and middle-income countries and changing healthcare systems.

Umair M, Marey A, Murali S et al. · NMR in biomedicine · (2026) · View on PubMed ↗ · Free PDF ↗

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Generated automatically on July 08, 2026. Covers PubMed articles published July 01, 2026 – July 08, 2026. Summaries are AI-generated; always consult the original publication for clinical or research decisions.