What's New in Cardiac MRI? — July 20, 2026
AI-summarised digest of 67 PubMed articles on Cardiac MRI published in the last 7 days.
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What’s New in Cardiac MRI?
July 20, 2026 · 67 articles · 15 research themes · covering July 13, 2026 – July 20, 2026
Overview
TODO
Athlete heart vs cardiomyopathy (differential diagnosis)
Severe Left Ventricular Dilation With Preserved Contractile Reserve in an Adolescent Elite Athlete.
This case studied an 18-year-old competitive male basketball athlete with exertional palpitations and atrial fibrillation, using multimodality cardiovascular imaging to distinguish physiologic remodeling from early cardiomyopathy. Evaluation showed severe left ventricular dilation (indexed end-diastolic volume 156 mL/m²) with moderately reduced ejection fraction (35–40%) and supraphysiologic tissue Doppler diastolic velocities, while cardiac magnetic resonance confirmed marked dilation without late gadolinium enhancement. Scientifically, it emphasizes that preserved contractile reserve and absent LGE can coexist with severe structural abnormalities, complicating differentiation between athletic remodeling and emerging cardiomyopathy.
Mutebi C, Chukwurah M, Chukumerije MT et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Physiologic Unmasking of an Anomalous Right Coronary Artery in a Competitive Lacrosse Athlete.
This case studied an 18-year-old competitive lacrosse player with progressive exertional dyspnea despite normal ECG, cardiac magnetic resonance, and nuclear stress testing. Baseline transthoracic echocardiography suggested anomalous right coronary artery (ARCA), and coronary computed tomography angiography confirmed an interarterial and intramural course with mild associated findings, demonstrating physiologic unmasking of the anomaly. The significance is that routine testing may miss exertional limitation in well-conditioned athletes, and CT angiography can be crucial when echocardiography raises suspicion for ARCA.
Chukwurah MI, Akele O, Bhatia R et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Differentiating an Athlete’s Heart and Cardiomyopathy: Role of Advanced Cardiac Imaging.
This case report studied how advanced cardiac imaging can distinguish athlete’s heart from cardiomyopathy in a 37-year-old male endurance athlete with cardiac enlargement detected on a coronary calcium scan. While ECG and echocardiography suggested exercise-induced physiological remodeling, cardiac magnetic resonance (CMR) identified multifocal myocardial scarring concerning for cardiomyopathy. The report highlights CMR as a clinically important tool when standard evaluation is equivocal, potentially changing diagnosis and management in athletes.
Jilani T, Khan S, Fakikh Y et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Apical Hypertrophic Cardiomyopathy and Elite-Level Sports: A 12-Year Follow-Up Case.
This 12-year follow-up case studied an asymptomatic elite athlete diagnosed with apical hypertrophic cardiomyopathy (aHCM) who participated in professional-level sports from ages 17 to 31. Despite long-term elite exercise, there were no adverse morphologic changes and no progression of apical fibrosis or disease after stopping professional sports. The report supports the concept that aHCM may have a more favorable long-term interaction with high-level athletic activity than other HCM phenotypes, informing risk counseling for athletes.
Thio Q, van Hattum J, Nijland F et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Performance-Enhancing Drug-Associated Myocarditis in a Young Athlete: From Cardiogenic Shock to Clearance.
This case report studied a 21-year-old athlete who developed fulminant myocarditis after performance-enhancing drug use. Cardiac magnetic resonance confirmed myocarditis after normal coronary angiography, and the patient improved from cardiogenic shock with inotropic support using diuresis and high-dose corticosteroids. The case highlights the need for careful, biomarker- and CMR-guided activity restriction and return-to-exercise decisions in athletes with drug-associated myocarditis.
Parks EA, Essig J, Pistiolis S · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac Remodeling and Dysfunction Associated in Populations With Obesity: An Analysis of Cardiac Structure and Function.
This systematic review and meta-analysis synthesized evidence from 2000–2025 comparing cardiac magnetic resonance (CMR) parameters in adults with obesity (WHO criteria) versus non-obese controls. The key finding was an obesity-related CMR phenotype characterized by consistent differences in myocardial structure/function and tissue/adiposity measures across included studies. This is significant because it provides a consolidated CMR-based framework for detecting subclinical cardiac remodeling in obesity and may guide risk assessment and future intervention trials.
Khanna S, Wilson D, Mann G et al. · Obesity reviews : an official journal of the International Association for the Study of Obesity · (2026) · View on PubMed ↗
Molecular and imaging biomarkers in myocardial ischemia/reperfusion injury: from pathogenetic mechanisms to therapeutic targeting.
This narrative review synthesized evidence on molecular and imaging biomarkers for myocardial ischemia/reperfusion injury (MIRI), linking mechanistic pathways (e.g., infarct expansion, microvascular obstruction, intramyocardial hemorrhage, and adverse remodeling) to biomarker-based detection and therapeutic targeting. The key finding was that while high-sensitivity cardiac troponins are central for necrosis diagnosis, they provide limited mechanistic insight into upstream MIRI processes, motivating broader biomarker panels. Scientifically, the review frames how emerging imaging and molecular biomarkers could improve mechanistic characterization and guide targeted interventions for MIRI.
Nasoufidou A, Bantidos MG, Kofos C et al. · Expert review of cardiovascular therapy · (2026) · View on PubMed ↗
Cardiac magnetic resonance imaging assessment of Del Nido versus cold blood cardioplegia in patients with low ejection fraction undergoing combined coronary artery bypass graft and mitral valve replacement: Early outcomes.
This single-center prospective study compared Del Nido cardioplegia (DNC) versus conventional cold blood cardioplegia (CBC) in 42 patients with low ejection fraction (LVEF <45%) undergoing concomitant coronary artery bypass grafting (CABG) and mitral valve replacement (MVR), with early myocardial functional recovery assessed by cardiac magnetic resonance (CMR). The key finding was that the cardioplegia strategy influenced early post-operative myocardial functional recovery as measured by CMR. Clinically, this suggests DNC may be a viable alternative to CBC for myocardial protection in high-risk patients undergoing combined CABG and MVR.
Gode S, Polat M, Eroğlu Polat A et al. · Turk gogus kalp damar cerrahisi dergisi · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac tumors and masses (imaging + pathology)
Shortness of Breath Due to a Large Spontaneous Left Atrial Intramural Hematoma.
This case studied a 58-year-old man with acute severe shortness of breath after marathon and 10-mile running, in whom echocardiography and cardiac magnetic resonance imaging were used to evaluate a large left atrial mass. Imaging showed intermediate T1 and slightly elevated T2 signal with no enhancement on first-pass or late gadolinium enhancement, leading to a diagnosis of spontaneous left atrial intramural hematoma confirmed at surgery. Clinically, it highlights how CMR signal characteristics can distinguish spontaneous left atrial intramural hematoma from other left atrial masses and guide urgent surgical management.
Mulder AAW, Vergeer D, Olsthoorn JR et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Right Atrial Mass in an Adolescent With a Complex Hematologic History: What Is the Diagnosis?
This case studied a 17-year-old female with hemoglobin SS sickle cell disease, Moyamoya disease, prior stroke, and pulmonary embolism, in whom cardiac magnetic resonance incidentally found a large pedunculated right atrial mass. The patient underwent cardiac catheterization for therapeutic removal and pathology, resolving the differential of thrombus versus tumor versus vegetation. The significance is that complex hematologic and thromboembolic histories require integrating clinical context with multimodality imaging to correctly diagnose right atrial masses.
Almasri M, Dalby S, Stallings-Archer K et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Mitral Valve Blood Cyst Discovered as an Incidentaloma in Trauma Evaluation.
This case studied a 31-year-old woman undergoing trauma evaluation after multiple stab wounds to the left chest, in whom imaging incidentally identified a mitral valve mass. Transesophageal echocardiography characterized a 2.0 × 1.5 cm cystic structure attached to the ventricular aspect of mitral A2/A3 scallops, consistent with a congenital mitral valve blood cyst. The significance is that rare valvular blood cysts can mimic thrombus or other traumatic cardiac injuries, so careful echocardiographic characterization prevents misdiagnosis and inappropriate intervention.
Bravo F, Ref J, Pullela N et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Leiomyosarcoma First Signaled by Chest Pain: Beyond Angina.
This case report examined a rare presentation of primary malignant cardiac tumor in a 49-year-old man with worsening exertional chest pain and dyspnea. Imaging was discordant—cardiac MRI favored a benign mass while echocardiography favored malignancy—and final pathology showed high-grade left atrial leiomyosarcoma with myxoid features. The findings emphasize the diagnostic value of multimodality imaging and the need for tissue diagnosis when imaging results conflict in suspected cardiac tumors.
Shakfeh K, Suma V, El Khoury G et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Incidental Cardiac Fibroma in a Young Soldier: Exercise Authorization and Graded Fitness-for-Duty Determination.
This case report described an incidental cardiac fibroma in a 25-year-old active-duty soldier identified after routine electrocardiographic screening with transthoracic echocardiography. The key finding was the detection of a well-circumscribed intramyocardial mass (20×20 mm) in the basal interventricular septum and the subsequent graded fitness-for-duty determination in the context of sports/exercise authorization. This highlights the need for evidence-informed guidance for exercise and occupational clearance when rare primary cardiac tumors like fibroma are discovered incidentally.
Demoulin R, Parsaï C, Bone ACK et al. · Military medicine · (2026) · View on PubMed ↗
Concomitant Hypertension in Hypertrophic Cardiomyopathy: Clinical Phenotype and Prognostic Associations of Cardiovascular Magnetic Resonance Biomarkers.
This registry-based cohort study compared CMR phenotypes and prognostic associations in hypertrophic cardiomyopathy (HCM) patients with concomitant hypertension versus those without, using data from the HCM-LGE registry (2008–2024). The key finding was that hypertension-defined HCM had distinct CMR characteristics and different long-term prognostic performance of CMR-derived biomarkers for all-cause mortality. This supports incorporating hypertension status when interpreting CMR biomarkers to better stratify risk in HCM.
Florence J, Gonçalves T, Toupin S et al. · European journal of preventive cardiology · (2026) · View on PubMed ↗
Cardiac aneurysm and post-ischemic structural sequelae
Long-Term Survival With Left Ventricular Aneurysm: The Cardiac Ball That Didn’t Burst.
This case report studied long-term outcomes of a giant left ventricular aneurysm (LVA) in a 58-year-old man with ischemic cardiomyopathy and heart failure with reduced ejection fraction. Multimodality imaging using transthoracic echocardiography and cardiac magnetic resonance confirmed a giant inferolateral LVA (12.0 × 8.6 × 7.2 cm), and although surgery was recommended, the patient declined. The case is significant because it documents unusually prolonged survival despite a large LVA, informing risk expectations and management discussions.
Encarnación-Martínez U, Arriaga-Páez F, Guillén-Ortiz CA et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Coronary intramural hematoma and trauma-related ischemic injury
Coronary Intramural Hematoma in a Young Athlete After Direct Ball Impact to the Chest.
This case report investigated coronary intramural hematoma (IMH) after blunt chest trauma in a 19-year-old competitive athlete. After troponin peaked at 20,400 ng/L and coronary angiography showed a nonobstructive ostial LAD lesion, cardiac MRI demonstrated near-transmural ischemic injury with microvascular obstruction and coronary CT angiography showed hyperdense mural thickening with positive remodeling. The report is clinically important because it links sports-related blunt impact to IMH and demonstrates how CMR/CT can characterize ischemic injury and vessel wall pathology.
Sakhi H, Kalifa L, Fradi S et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Myocarditis and drug-associated myocarditis in athletes/patients
Mesalazine-Induced Myocarditis: A Challenging Diagnostic Journey.
This clinical case report describes a patient who developed acute chest pain and elevated cardiac biomarkers shortly after starting mesalazine, ultimately diagnosed with mesalazine-induced myocarditis. Cardiac MRI was pivotal for diagnosis, and prompt discontinuation of mesalazine led to rapid clinical recovery. The report emphasizes early recognition and MRI-based confirmation of drug-induced myocarditis to prevent progression to severe complications.
Bouayed MZ, Benaini I, Koulali H et al. · Clinical case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Premature Ventricular Contractions as a Result of Subacute Myocarditis in a Professional Football Player.
This case studied a 33-year-old professional football player undergoing return-to-play evaluation for premature ventricular contractions (PVCs) and atypical chest pain. ECG showed fragmented R waves and PVCs, cardiac magnetic resonance demonstrated late gadolinium enhancement consistent with subacute myocarditis, and after 2–3 months of rest plus guideline-directed medical therapy, risk stratification supported management decisions for athletic participation. Scientifically and clinically, it illustrates a multimodality approach (ECG, CMR, PET) to reduce diagnostic uncertainty when myocarditis is suspected as the cause of PVCs in athletes.
Pirquet C, Underberg D, Osler B et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Arrhythmogenic cardiomyopathy and inherited arrhythmia risk
Pleiotropic Phenotype of RYR2 Exon 3 Deletion: Biventricular Noncompaction and Malignant Arrhythmias.
This JACC Case Reports report describes a 33-year-old woman with an RYR2 exon 3 deletion (E3DS) presenting with pregnancy-associated premature ventricular contractions and later developing biventricular noncompaction, sinus node dysfunction, and malignant arrhythmias. Electrophysiology testing showed complete supranodal atrioventricular block with extensive right atrial low-voltage areas, and cardiac MRI confirmed biventricular noncompaction, with persistent bradyarrhythmia postpartum. The case highlights the pleiotropic phenotype of RYR2 exon 3 deletion (structural cardiomyopathy plus severe conduction/arrhythmia disease), informing clinicians to consider ryanodinopathy in similar presentations.
Faucher L, Cardi T, Fitouchi S et al. · JACC. Case reports · (2026) · View on PubMed ↗
Exercise-Provoked Wide-Complex Tachycardia and Extreme Duke Score: Orthodromic Reciprocating Tachycardia Unmasked by Electrophysiology Study.
This 2026 JACC Case Reports report described a 44-year-old man who developed exercise-provoked sustained wide-complex tachycardia with left bundle branch block morphology during stress-test recovery. Electrophysiology study unmasked orthodromic reciprocating tachycardia mediated by a concealed left posterior accessory pathway, after angiography and cardiac MRI excluded obstructive and structural heart disease. The case emphasizes that supraventricular tachycardia with aberrancy can mimic ventricular tachycardia during exercise testing, and that electrophysiology study is crucial for correct diagnosis and management.
Ray N, Petty A, Money D et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Fabry disease cardiomyopathy: Time for a closer heart rhythm monitoring?
This 2026 narrative review evaluated whether closer heart rhythm monitoring is needed in Fabry disease cardiomyopathy to better identify patients at risk of sudden cardiac death (SCD). It summarized evidence on Fabry disease (Anderson-Fabry disease) arrhythmia pathophysiology and argued that standard intermittent monitoring such as 24-hour Holter can miss paroxysmal, asymptomatic lethal arrhythmias. The review supports reconsidering monitoring strategies to improve risk stratification for lethal arrhythmic events in Fabry disease.
Mugnai G, Genovese D, De Michieli L et al. · Heart failure reviews · (2026) · View on PubMed ↗
Syncope and Scar in a Former Elite Basketball Player.
This case studied a 47-year-old former elite basketball player presenting with exertional syncope and evaluated for late sequelae of myocarditis-related ventricular tachycardia (VT). Cardiac magnetic resonance showed an inferolateral scar consistent with prior myocarditis, coronary angiography excluded obstructive coronary disease, and electrophysiology testing demonstrated inducible VT leading to implantable cardioverter-defibrillator placement. The clinical significance is improved risk stratification for VT in athletes with scar on CMR, supporting appropriate device therapy to prevent sudden cardiac events.
Garba DL, Aronis KN, Barouch LA et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Myocardial Inflammation Reveals a Genetic Desmosomal Cardiomyopathy in an Athlete.
This case studied a 32-year-old female athlete with bradycardia, troponin elevation, and high PVC burden, using cardiac magnetic resonance, endomyocardial biopsy, and genetic testing to evaluate overlapping myocarditis and inherited cardiomyopathy. Biopsy confirmed acute lymphocytic myocarditis and genetic testing identified a likely pathogenic PKP2 variant, consistent with a genetic desmosomal cardiomyopathy phenotype. The significance is that myocardial inflammation can unmask arrhythmogenic cardiomyopathy, and PKP2 testing can clarify etiology and inform long-term management in athletes.
Kueppers ST, Magnussen C, Waldeyer C et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Left-Dominant Arrhythmogenic Cardiomyopathy in a Young Athlete: Silent Danger on the Pitch.
This case studied a 21-year-old athlete with neurologic symptoms and chest discomfort, evaluated for arrhythmogenic left ventricular cardiomyopathy (ALVC) with a myocarditis-like “hot phase.” Cardiac imaging showed LV dilation, apical hypokinesia, apical thrombus, and multifocal nonischemic late gadolinium enhancement with edema, but progressive LV remodeling with persistent LGE and endomyocardial biopsy showing low-grade inflammation supported ALVC rather than transient myocarditis. The clinical significance is that ALVC can mimic myocarditis and still carry ventricular arrhythmia risk, so persistent CMR abnormalities and biopsy findings should prompt cardiomyopathy-directed management.
Esteves S, Cazeiro DI, Guimarães T et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac MRI as surveillance and risk stratification of arrhythmogenic foci in long-chain hydroxyacyl-CoA dehydrogenase deficiency.
This case report studied cardiac MRI as a surveillance tool for arrhythmogenic substrates in a 22-year-old woman with long-chain hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency. Over serial cardiac MRIs, the patient showed stable myocardial scar burden but evolving septal hypertrophy despite preserved ventricular function. The report is significant because it supports MRI-based longitudinal monitoring for early detection of arrhythmogenic risk in fatty-acid oxidation disorders before overt functional decline.
Kantheti H, Natarajan R, Yuvaraj R et al. · Proceedings (Baylor University. Medical Center) · (2026) · View on PubMed ↗
Ventricular Tachycardia in a Young Athlete With Prior Myocarditis and MYL2 Mutation.
This case report studied a 23-year-old female competitive soccer player with prior myocarditis and a MYL2 mutation who underwent monitored return to play. Although she recovered with activity restriction and had normal follow-up imaging and testing, she developed a 42-second episode of polymorphic ventricular tachycardia while sprinting. The report underscores that inherited cardiomyopathy risk (MYL2) can persist or emerge despite apparent myocarditis recovery, supporting cautious, genotype-informed athletic clearance.
Burka S, Garba D, Barouch LA et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac MRI-Derived Right Ventricular Strain for Risk Stratification in Pediatric and Adolescent Arrhythmogenic Cardiomyopathy: A Multicenter Cohort Study.
This multicenter cohort study evaluated pediatric and adolescent patients (≤18 years) with arrhythmogenic cardiomyopathy (ACM) to determine whether cardiac MRI-derived right ventricular global longitudinal strain (RVGLS) improves risk stratification beyond conventional clinical and CMR markers. The key finding was that RVGLS had prognostic and incremental value for predicting severe cardiac outcomes in this underrepresented population. Clinically, incorporating RVGLS into CMR-based assessment could improve identification of high-risk pediatric/adolescent ACM patients for closer monitoring and management.
Xu W, Sa F, Song Y et al. · JACC. Cardiovascular imaging · (2026) · View on PubMed ↗
Hypertrophic cardiomyopathy (HCM): trials, prognosis, and phenotype modifiers
Clinical phenotype and outcomes of low-risk HCM patients who maintained stable exercise habits during follow-up.
This study evaluated 253 low-risk hypertrophic cardiomyopathy (HCM) patients who maintained reliably documented stable exercise habits during follow-up, stratifying them into sedentary, mild, and vigorous exercise groups. The key finding was that sustained exercise participation identified a subgroup with a more favorable clinical phenotype and follow-up outcomes compared with sedentary patients within the low-risk category. These data suggest that, in carefully selected low-risk HCM patients, stable regular exercise may be associated with improved longitudinal outcomes.
Pelliccia A, Ferrera A, Daniello CD et al. · International journal of cardiology · (2026) · View on PubMed ↗
Trientine for hypertrophic cardiomyopathy: a phase 2 trial.
This phase 2 trial studied trientine dihydrochloride in people with hypertrophic cardiomyopathy (HCM) to test whether copper chelation and improved intracellular copper I trafficking can reduce disease features linked to mitochondrial dysfunction and fibrosis. The key finding reported in the abstract is that trientine was evaluated for efficacy and safety in HCM based on preclinical evidence of improved mitochondrial function and reduced left ventricular hypertrophy and fibrosis. The trial is clinically significant because it targets a mechanistic pathway (copper handling and mitochondrial energy deficiency) that could translate into a disease-modifying therapy for HCM.
Farrant JP, Dodd S, Rosala-Hallas A et al. · European heart journal · (2026) · View on PubMed ↗ · Free PDF ↗
Vascular remodeling and microvascular dysfunction (including HFpEF/CMD)
Understanding HFpEF Through Imaging: Strengths, Limitations, and Current State of the Art.
This 2026 JACC Cardiovascular Imaging State-of-the-Art review synthesized evidence on imaging approaches for diagnosing and phenotyping heart failure with preserved ejection fraction (HFpEF) and linked multimodality imaging to invasive hemodynamics. It concluded that echocardiography and other noninvasive imaging are first-line tools, but that current noninvasive indices can lack sensitivity because resting diastolic pressures may be normal and HFpEF pathophysiology extends beyond isolated diastolic dysfunction. The review highlights how integrating imaging with invasive hemodynamic measurements could improve HFpEF diagnosis and mechanistic understanding.
Harada T, Naser JA, Ghanbari F et al. · JACC. Cardiovascular imaging · (2026) · View on PubMed ↗
Left ventricular end-diastolic pressure in women with ischemia and no obstructive coronary artery disease: The women’s ischemia syndrome evaluation - Coronary microvascular dysfunction study (WISE-CVD).
This 2026 WISE-CVD study investigated women (n=253) with ischemia and no obstructive coronary artery disease (INOCA) to determine how coronary microvascular dysfunction (CMD) relates to elevated left ventricular end-diastolic pressure (LVEDP). Using invasive coronary functional testing to measure resting LVEDP and coronary microvascular function, with a predefined subset undergoing cardiac MRI, the study tested the hypothesis that CMD-mediated impairment in LV relaxation contributes to higher LVEDP. The results aim to improve mechanistic understanding and clinical phenotyping of CMD-associated HFpEF physiology in women.
Ranasinghe S, Tjoe B, Chang J et al. · International journal of cardiology · (2026) · View on PubMed ↗ · Free PDF ↗
Vascular changes in hypertrophic cardiomyopathy.
This review summarized evidence on vascular changes in hypertrophic cardiomyopathy (HCM), focusing on microvascular dysfunction and structural vascular remodeling across disease severity. It synthesizes modalities used to assess vascular function (cardiac and peripheral) and links vascular abnormalities to progression involving fibrosis and clinical outcomes. The review is significant because it frames vascular pathology as a potential driver of HCM progression and a target for future risk stratification and therapies.
Visch JE, Nassar A, Burchell G et al. · Cardiovascular research · (2026) · View on PubMed ↗ · Free PDF ↗
Heart failure and cardiomyopathy progression/monitoring (general)
Reverse Remodeling in Pediatric Myocarditis With DCM Phenotype Impact of rASD and PAB.
This retrospective JACC Advances study analyzed 31 children under 3 years old with biopsy-proven myocarditis and a dilated cardiomyopathy (DCM) phenotype to evaluate a staged, pathophysiology-guided strategy combining left atrial decompression and pulmonary artery banding (PAB). The key finding was that this approach was associated with reverse remodeling in selected infants/young children, with outcomes suggesting benefit from targeting hemodynamic drivers during early disease. Clinically, it supports an age- and mechanism-guided interventional pathway to promote myocardial recovery and potentially delay progression to end-stage heart failure in pediatric myocarditis with DCM phenotype.
Logeswaran T, Akintürk H, Schranz D et al. · JACC. Advances · (2026) · View on PubMed ↗ · Free PDF ↗
[Diagnostic and therapeutic challenges in pediatric takotsubo syndrome: a case report].
This 2026 pediatric case report described diagnostic and therapeutic challenges in takotsubo syndrome in a 15-year-old adolescent with Barlow syndrome and severe mitral regurgitation undergoing mechanical mitral valve replacement. Intraoperative findings suggested endocarditis and were subsequently confirmed, illustrating how takotsubo-like presentations can overlap with postoperative hemodynamic deterioration etiologies. The report underscores the need for careful differential diagnosis in children when acute cardiomyopathy occurs in complex surgical settings.
Maza-Caneva OC, Villa-Vargas RA, Restrepo-Hincapié AC et al. · Archivos de cardiologia de Mexico · (2026) · View on PubMed ↗ · Free PDF ↗
Quantitative CMR-derived pulmonary circulation imaging biomarkers in recent-onset dilated cardiomyopathy associated with pulmonary hemodynamics and clinical improvement.
This retrospective study evaluated quantitative pulmonary circulation imaging biomarkers (PCIB) derived from cardiovascular magnetic resonance (CMR) in 90 recent-onset dilated cardiomyopathy (RODCM) patients with baseline and 1-year follow-up imaging. After excluding 26 patients with myocarditis confirmed by endomyocardial biopsy, the study assessed associations between PCIB, pulmonary hemodynamics/pulmonary hypertension, systolic and diastolic function, and clinical improvement. The work is significant because it supports CMR-based pulmonary vascular biomarkers as potential tools for risk assessment and monitoring therapeutic response in early-stage DCM.
Opatřil L, Mojica-Pisciotti ML, Panovský R et al. · BMC medical imaging · (2026) · View on PubMed ↗ · Free PDF ↗
CMR Findings Across Disease Phases in Takotsubo Syndrome: Insights From the Multicenter EVOLUTION Registry.
This retrospective multicenter EVOLUTION registry analysis studied 439 patients with Takotsubo syndrome (400 females; mean age ~70 years) and compared cardiac magnetic resonance (CMR) findings across disease phases defined by time from symptom onset to CMR (acute 1–72 hours, subacute 4–21 days, late ≥22 days). The key finding was that CMR tissue and functional characteristics differed by acquisition phase, reflecting dynamic myocardial changes over time. These phase-specific CMR insights can improve interpretation of imaging in Takotsubo syndrome and support more accurate timing of diagnosis and follow-up.
Cau R, Luetkens J, Pontone G et al. · The American journal of cardiology · (2026) · View on PubMed ↗ · Free PDF ↗
The CAMERA-MRI Score to Predict LVEF Normalization Post Ablation for Primary Atrial Fibrillation Mediated Cardiomyopathy: a Pooled Analysis of Two Randomized Clinical Trials.
This pooled analysis studied predictors of left ventricular ejection fraction (LVEF) normalization after catheter ablation in patients with primary atrial fibrillation (AF)-mediated cardiomyopathy using baseline and serial CMR from the CAMERA-MRI and CAMERA-MRI II randomized trials. The key finding was that the CAMERA-MRI score (and its components) could stratify which patients were more likely to achieve post-ablation LVEF normalization. This supports a CMR-based, prospective risk prediction tool to guide expectations and management in AF-mediated cardiomyopathy.
Cho KK, Segan L, Anthony C et al. · Heart rhythm · (2026) · View on PubMed ↗
Differential Biventricular Strain Recovery With Selective Fibrosis Biomarker Regression After Sleeve Gastrectomy: A Prospective CMR Feature-Tracking Study.
In a single-center prospective cohort of 32 patients with paired follow-up CMR after laparoscopic sleeve gastrectomy (LSG), this study used CMR feature-tracking (CMR-FT) to assess differential biventricular and biatrial strain recovery alongside fibrosis and adipokine biomarkers. The key finding was that regression of fibrosis biomarkers and changes in myocardial deformation were not uniform across chambers, showing differential biventricular strain recovery after LSG. This suggests that cardiac reverse remodeling after bariatric surgery may follow distinct timelines and mechanisms, which could refine monitoring and therapeutic targeting.
Akarsu H, Kılıç İD, Dodurga Y et al. · Obesity surgery · (2026) · View on PubMed ↗
Topical vascular organoid therapy promotes microvascular regeneration and functional recovery in porcine ischemic cardiomyopathy.
This preclinical study tested a scaffold-free topical vascular organoid therapy composed of human endothelial progenitor cells (EPCs) and mesenchymal stem cell-derived smooth muscle cells (SMCs) in a porcine model of ischemic cardiomyopathy. Four weeks after transplantation onto the left ventricular surface, cardiac MRI showed preserved left ventricular ejection fraction and modest improvement in regional function versus controls. These results support the scientific potential of EPC-SMC organoids to regenerate microvasculature and improve functional recovery beyond epicardial revascularization.
Farag JA, Yajima S, Kawai Y et al. · Stem cell reports · (2026) · View on PubMed ↗ · Free PDF ↗
Thrombus detection and thromboembolic risk (CMR-guided)
Determinants, risk score, and prognostic implications of left ventricular thrombus in ischemic cardiomyopathy assessed by cardiac magnetic resonance: a retrospective cohort study.
This retrospective cohort study evaluated 790 patients with chronic ischemic cardiomyopathy (LVEF <50%, >40 days post–myocardial infarction) who underwent cardiac magnetic resonance (CMR) to detect left ventricular thrombus (LVT) and to identify associated risk factors and prognostic implications. CMR-detected LVT was associated with worse major adverse cardiovascular events (MACE), and the authors developed a CMR-based risk score to stratify risk in chronic ICM. These findings support CMR-guided identification and risk stratification of LVT in chronic ischemic cardiomyopathy to inform closer surveillance and management.
Aramcharoen C, Buraphat P, Wanitanantakun T et al. · Annals of medicine · (2026) · View on PubMed ↗ · Free PDF ↗
Congenital heart disease and long-term surveillance
The Right Atrium and Atrialised Right Ventricle are Associated with Cardiac Output During Exercise in Patients with Ebstein Anomaly of the Tricuspid Valve.
This study investigated the relationship between right-sided cardiac volumes and exercise performance in 13 un-operated pediatric patients (median age 13.5 years) with Ebstein anomaly of the tricuspid valve. Using exercise testing and resting/exercise cardiac magnetic resonance imaging, it assessed how right atrial volume and atrialised right ventricle volume relate to cardiac output (cardiac index) and exercise capacity (%VO2max). The findings are significant because they identify right atrial and atrialised right ventricular contributions to exercise physiology, potentially informing functional assessment in Ebstein anomaly.
Gnanappa GK, Luxford J, Dryburgh L et al. · Pediatric cardiology · (2026) · View on PubMed ↗ · Free PDF ↗
Multimodality Imaging of Pulmonary Regurgitation and Right Ventricular Remodeling in Adults With Repaired Tetralogy of Fallot: A Descriptive Single-Center Case Series.
This descriptive single-center case series studied seven adults with surgically repaired tetralogy of Fallot (TOF) who underwent serial transthoracic echocardiography (TTE) and at least two cardiac magnetic resonance (CMR) examinations over 5 to >15 years. The key finding was that multimodality imaging characterized chronic pulmonary regurgitation (PR) and right ventricular (RV) remodeling trajectories over long-term follow-up. These longitudinal imaging patterns can inform timing and decision-making for pulmonary valve replacement (PVR) in repaired TOF patients.
AlRahimi J · Cardiology · (2026) · View on PubMed ↗ · Free PDF ↗
Effects of Dehydroepiandrosterone in Pulmonary Hypertension (EDIPHY): A Randomized, Double-Blind, Placebo-Controlled Crossover Trial.
This randomized, double-blind, placebo-controlled crossover trial tested whether dehydroepiandrosterone (DHEA) improves right ventricular (RV) function in participants with pulmonary arterial hypertension (PAH), using cardiac magnetic resonance (CMR) to measure RV longitudinal strain over 18 weeks. DHEA showed no effect on RV longitudinal strain compared with placebo. These findings suggest that correcting low DHEA/DHEA-S levels is not an effective strategy for improving RV systolic deformation in PAH, at least on the studied time scale and outcome.
Sanders R, Walsh T, Baird GL et al. · Annals of the American Thoracic Society · (2026) · View on PubMed ↗
Long-Term Follow-Up With Cardiovascular Magnetic Resonance in 2 Patients With Isolated Left Ventricular Apical Hypoplasia.
This JACC Case Reports report described two patients with isolated left ventricular apical hypoplasia who underwent serial cardiovascular magnetic resonance imaging over more than a decade from childhood into early adulthood. The key finding was that ventricular morphology and function remained relatively stable over long-term follow-up in both cases. The long follow-up is scientifically significant because it helps clarify the natural history of this rare congenital anomaly and supports the role of CMR for longitudinal surveillance.
Isenia C, Hassing HC, Constantinescu AA et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Valvular disease and pericarditis (including recurrent pericarditis)
Recurrent Pericarditis in a Rugby Player: Imaging-Guided Therapy.
This case studied a 26-year-old rugby player with recurrent pericarditis after atrial septal defect repair, using cardiac magnetic resonance and inflammatory biomarkers to guide imaging-guided therapy. The patient achieved remission on rilonacept despite moderate pericardial late gadolinium enhancement on initial CMR, and relapse occurred 11 months after tapering when rilonacept was stopped, with rapid response after reinitiation. Clinically, it supports using CMR and biomarkers to inform tapering decisions in recurrent pericarditis to balance relapse risk with return-to-play considerations.
Abuawad A, Badwan O, Ehsan M et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac imaging methods, AI, and reconstruction (CMR/4D flow/fetal)
Training Deep Learning Based Dynamic MR Image Reconstruction Using Synthetic Fractals.
This study investigated whether deep learning dynamic MRI reconstruction models trained on synthetically generated quaternion Julia fractal data (2D+t) can replace or supplement models trained on natural video and cardiac MRI datasets. The key finding was that a 3D U-Net artifact-suppression model trained on synthetic fractal data (F-DL) performed comparably to or better than models trained on natural videos (NV-DL) and cardiac MRI data (CMR-DL) for dynamic reconstruction from radially undersampled multi-coil k-space. This provides a privacy- and availability-friendly training strategy for dynamic MRI reconstruction that could accelerate deployment of reconstruction networks in clinical settings.
Raman A, Jaubert O, Wrobel M et al. · Magnetic resonance in medicine · (2026) · View on PubMed ↗
Cardiovascular 4D Flow MRI for multidirectional hemodynamic assessment: a single-centre observational study.
This single-centre observational study evaluated the feasibility and clinical utility of cardiovascular four-dimensional flow MRI (4D Flow MRI) in 30 cardiovascular MRI cases acquired on a Siemens MAGNETOM Skyra 3.0-T system using time-resolved, velocity-encoded 4D flow with retrospective ECG gating and respiratory compensation. The study found that the technique enabled multidirectional hemodynamic visualization and quantitative assessment using region-adjusted velocity encoding. These results support 4D Flow MRI as a practical noninvasive tool for detailed cardiovascular flow characterization that may improve hemodynamic assessment beyond conventional imaging.
Ye Y, Zeng T, Chen Y et al. · Biomedizinische Technik. Biomedical engineering · (2026) · View on PubMed ↗ · Free PDF ↗
Impact of transcatheter aortic valve replacement on blood flow in the ascending aorta and brachiocephalic artery.
This prospective study evaluated patients undergoing transcatheter aortic valve replacement (TAVR) for aortic stenosis using four-dimensional flow cardiovascular magnetic resonance (4D flow CMR) before and after the procedure. It assessed changes in blood flow in the ascending aorta and brachiocephalic artery and tested whether the magnitude of post-TAVR flow increase depended on pre-TAVR flow rate. The findings are intended to clarify how baseline aortic arch flow physiology influences hemodynamic response after TAVR, informing post-procedural assessment using 4D flow CMR.
Yamasaki K, Tsuneta S, Kanaya M et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac MRI Reconstruction Using Diffusion Priors and Multi-Scale Transformer-Based Feature Modeling.
This 2026 IEEE Journal of Biomedical and Health Informatics paper proposed a diffusion-based multi-scale feature fusion transformer (DMFT) for cardiac MRI reconstruction. The method was designed to address transformer-based limitations such as poor high-frequency detail recovery, inconsistent structure under undersampling, and limited interpretability by incorporating diffusion priors and multi-scale feature modeling. If validated clinically, this approach could improve reconstruction quality and reliability for real-world cardiac MRI workflows under accelerated acquisition.
Lyu J, Zhao B, Al-Hazzaa SAF et al. · IEEE journal of biomedical and health informatics · (2026) · View on PubMed ↗
Fast and scalable annotation-free LV-centered ROI localisation in stress perfusion cardiac MRI.
This study developed and tested an annotation-free left ventricle (LV)-centered region-of-interest (ROI) localization pipeline for stress perfusion cardiac MRI in a scalable, automated manner. The method uses Fast Fourier Transform-based localization with Sobel edge refinement and a heuristic fallback, then applies a circular ROI post-processing step to generate consistent LV-centered ROIs directly from raw perfusion frames without task-specific labels. This could reduce the need for manual annotation and accelerate stress perfusion CMR analysis workflows where labeled datasets are scarce.
Kalashami MP, Fagioli A, Marini MR et al. · Computers in biology and medicine · (2026) · View on PubMed ↗
Generative MR Multitasking With Complex-Harmonic Cardiac Encoding: Bridging the Gap Between Gated Imaging and Real-Time Imaging.
This methodological study developed a generative MR multitasking reconstruction framework for cardiac MRI that bridges gated imaging and real-time imaging using complex-harmonic cardiac encoding. Using a conditional variational autoencoder (CVAE), it learns implicit neural temporal bases from sequence timings and models cardiac motion as a complex harmonic with latent amplitude capturing beat-to-beat variability, enabling unified reconstruction across free-breathing and gated-like/time-resolved views. The approach aims to reduce the gap between gated and real-time cardiac MRI, potentially improving quantitative and motion-robust imaging.
Fang X, Christodoulou AG · Magnetic resonance in medicine · (2026) · View on PubMed ↗ · Free PDF ↗
Standardized Acquisition of Fetal Cardiac Cine MRI: A Practical Guide.
This practical guide article describes standardized acquisition methods for fetal cardiac cine MRI, focusing on overcoming limitations of fetal cardiac assessment by using advances in fetal rhythm monitoring for retrospective gating and motion compensation. The key contribution is a reproducible, standardized cine MRI protocol intended to enable systematic fetal cardiac evaluation despite variable fetal position and maternal factors that affect ultrasound. Standardization is clinically significant because it can improve feasibility and comparability of fetal cardiac MRI across centers, supporting broader adoption for prenatal cardiac assessment.
Biechele G, de Vries F, Stos B et al. · Circulation. Cardiovascular imaging · (2026) · View on PubMed ↗
AI Model Improves Interpretation of Cardiac Magnetic Resonance Imaging Scans.
This News and Perspectives report describes emerging research on an AI tool intended to improve the interpretation of cardiac magnetic resonance (CMR) scans, addressing the time and specialist expertise required for manual reading. The key finding is that AI-assisted interpretation can enhance accuracy and efficiency compared with conventional workflows. Scientifically and clinically, such tools could streamline CMR reporting and potentially improve consistency of cardiac imaging interpretation.
Narang SK · Journal of medical Internet research · (2026) · View on PubMed ↗ · Free PDF ↗
Quantitative imaging biomarkers (strain, ECV, radiomics, feature tracking)
Advancing Heart Ageing in Ischemic Heart Disease: Insights from CMR and ECG Analysis.
This study assessed biological heart ageing in prevalent ischemic heart disease (IHD) cases (n=2,142) by estimating heart age using advanced cardiac magnetic resonance (CMR) radiomics features and electrocardiogram (ECG) phenotypes. The key finding was that IHD was associated with an increased heart age gap (HAG), and conventional imaging indices and vascular risk factors contributed to the biological age estimation. Scientifically, it supports CMR+ECG-derived biomarkers as measurable indicators of accelerated cardiac ageing in IHD and may enable risk stratification beyond traditional clinical measures.
Salih AM, Rauseo E, Galazzo IB et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
Fully Automatic Left Atrial Strain Quantification via Multi-task Learning on Cardiac Cine MRI.
This multi-center study developed a fully automatic left atrial (LA) strain quantification method using multi-task learning on cardiac cine MRI, addressing limitations of manual/landmark feature tracking and contouring errors. The model used groupwise registration plus segmentation with a spatiotemporal cross-attention module and synergistic losses to quantify LA strain directly from two- and four-chamber cine images, outperforming or matching conventional feature tracking approaches (e.g., optical flow and other algorithms). This improves reproducibility and scalability of LA strain measurement for clinical research and potential routine use.
Zhao Y, Chen H, Gong Y et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
Septal thickness to QRS voltage ratio in Lead I/aVR: A simple tool for estimating cardiac amyloid burden.
This study evaluated whether an integrated echocardiographic-electrocardiographic (echo-ECG) index—maximum septal thickness (MST) divided by QRS voltage in lead I and/or aVR—correlates with cardiac magnetic resonance (CMR) extracellular volume (ECV) as a reference measure of cardiac amyloid burden. The key finding was that the MST/QRS voltage ratio showed meaningful correlation with CMR-derived ECV, offering a simpler surrogate for amyloid burden. This could improve accessibility of noninvasive amyloidosis risk stratification where ECV measurement is limited by cost or availability.
Sclafani M, Arcari L, Tini G et al. · International journal of cardiology · (2026) · View on PubMed ↗ · Free PDF ↗
Epidemiology, prevention, and population risk (aging, tobacco, obesity, environment)
Clinical spectrum and ascertainment pathways in pediatric female dystrophinopathy.
This single-center retrospective case series characterized 35 genetically confirmed pediatric girls with DMD gene variants to define the clinical spectrum, ascertainment pathways, subclinical muscle involvement, and inheritance patterns of female dystrophinopathy. The study found that presentations ranged from asymptomatic at evaluation to subtle childhood skeletal muscle and cardiac manifestations, with ascertainment differing between symptom-driven detection and identification through other pathways. These results improve recognition and diagnostic strategy for female dystrophinopathy, supporting earlier surveillance for cardiac and muscle involvement in affected girls.
Jiao H, Bai J, Li P et al. · Italian journal of pediatrics · (2026) · View on PubMed ↗ · Free PDF ↗
Ischemic heart disease mortality with documented tobacco use in the United States, 1999-2023: a nationwide population-based analysis.
This nationwide U.S. population-based analysis used CDC mortality data (1999–2023) to quantify ischemic heart disease (IHD; ICD-10 I20–I25) mortality trends among adults aged ≥25 years with documented tobacco use disorder (ICD-10 F17 as a contributing cause). The key finding was that IHD mortality associated with documented tobacco use persisted over time and showed measurable temporal trends using joinpoint regression (annual percent change and average annual percent change). Clinically, the results reinforce tobacco use as a major driver of IHD mortality and support targeted prevention and cessation efforts to reduce premature cardiovascular deaths.
Ibrahim AA, Tariq Z, Samad A et al. · Archives of public health = Archives belges de sante publique · (2026) · View on PubMed ↗ · Free PDF ↗
Associations of thoracic muscle area factor and visceral adiposity with cardiac function in patients with overweight or obesity.
This 2026 observational study assessed 154 overweight/obese patients who underwent cardiac magnetic resonance to test independent and interactive associations between thoracic axial skeletal muscle mass (TASM) factor, visceral adiposity, and cardiac function. TASM factor was positively associated with left ventricular ejection fraction (EF) and global circumferential strain (GCS), while visceral fat showed associations with cardiac biomarkers including N-terminal pro–B-type natriuretic peptide (NT-proBNP). These findings suggest that CMR-derived body composition metrics (muscle and visceral fat) may help characterize cardiac functional status and risk in people with overweight/obesity.
Gao L, Cheng L, Liu W et al. · Nutrition, metabolism, and cardiovascular diseases : NMCD · (2026) · View on PubMed ↗
Mapping chemical footprints: A baseline assessment for organochlorine pesticides and polychlorinated biphenyls in coastal sediments of Greece (eastern Mediterranean Sea).
This 2026 Marine Pollution Bulletin study performed a baseline environmental assessment of organochlorine pesticides (24 substances) and polychlorinated biphenyls (25 substances) in coastal sediments across 48 sites in Greece. Surface sediments collected in March 2023 and March 2024 were analyzed to characterize pollution levels and infer potential sources of these persistent, bioaccumulative contaminants. The work provides a reference dataset for monitoring long-term contamination and potential remobilization into marine ecosystems in the eastern Mediterranean.
Parinos C, Skavantzou T, Plakidi E et al. · Marine pollution bulletin · (2026) · View on PubMed ↗ · Free PDF ↗
Population aging and changes in mortality from four major noncommunicable diseases in Suzhou, China: a population-based study from 2000 to 2020.
This population-based study analyzed how population aging affected mortality trends from four major noncommunicable diseases—cancer, cardiovascular disease, chronic respiratory disease, and diabetes—in Suzhou, China from 2000 to 2020. Using household-registered population data and death records, the study quantified changes in crude and age-standardized mortality (Segi world standard), years of life lost, and premature mortality over time. The results are significant for public health planning by clarifying how demographic aging may drive future NCD mortality burdens.
Huang C, Bai M, Hua Y et al. · BMC public health · (2026) · View on PubMed ↗ · Free PDF ↗
Initial experience with primary and redo robotic pyeloplasty using the Versius robotic system (CMR).
This retrospective study evaluated outcomes of primary and redo robotic pyeloplasty using the Versius robotic system (CMR) in patients treated at Pakistan Kidney and Liver Institute & Research Center (PKLI&RC), Lahore. Across 74 patients operated between May 2023 and July 2025, the study assessed perioperative parameters and surgical outcomes for both initial and repeat procedures. The findings provide early real-world evidence for feasibility and effectiveness of the Versius platform in PUJO management, including redo cases.
Zafar N, Nusrat NB, Muhammad S et al. · Urologia · (2026) · View on PubMed ↗
HERZCHECK: Early Detection of Subclinical Preheart Failure Using Mobile Cardiac Magnetic Resonance and Telemedicine in Rural and Underressourced Regions.
The HERZCHECK cross-sectional cohort study evaluated a fully mobile, telemedicine-supervised cardiac MRI screening algorithm for subclinical pre-heart failure in asymptomatic adults aged 40–69 years with cardiovascular risk factors in rural and underresourced regions across 12 sites in Germany. The key finding was that a standardized, ubiquitously applicable mobile CMR approach could be implemented as a screening tool for pre-HF, addressing the lack of validated algorithms. If validated prospectively, this workflow could enable earlier identification of at-risk individuals and support preventive interventions before symptomatic heart failure develops.
Kelle S, Müller ML, Beyer RE et al. · Circulation. Heart failure · (2026) · View on PubMed ↗
The contribution of adolescent cardiovascular disease risk factors to vascular stiffness and cardiac remodelling in young adults.
Using Raine Study participants classified by adolescent cardiovascular risk (cluster analysis at age 17) and re-assessed in young adulthood at age 27, this study examined how adolescent risk factors relate to vascular stiffness (pulse wave velocity) and cardiac remodeling/function measured by cardiac MRI, including LV/RV/LA strain and LV mass index. The key finding was that higher adolescent cardiovascular risk was associated with greater vascular stiffness and adverse cardiac remodeling/functional measures in young adulthood. This is significant because it links early-life risk stratification to measurable CMR phenotypes that may identify targets for earlier intervention to prevent future cardiovascular disease.
Barden AE, Beilin LJ, Lan NSR et al. · European journal of preventive cardiology · (2026) · 2 citations · View on PubMed ↗ · Free PDF ↗
Colorectal anastomotic safety assessment using ICG fluorescence and flexible endoscopy (COLOSSEUM): a global survey of 1367 surgeons.
The COLOSSEUM study surveyed 1367 colorectal surgeons worldwide to characterize real-world practice patterns for colorectal anastomotic safety assessment using indocyanine green (ICG) fluorescence and flexible endoscopy (FE). The key finding was substantial global variation in how surgeons use ICG and FE, reflecting differences in institutional practice and implementation. This is clinically significant because it highlights the need for structured recommendations or standardization to reduce intersurgeon variability and potentially improve anastomotic outcomes.
Belvedere A, Licardie E, Sochorova D et al. · Surgical endoscopy · (2026) · View on PubMed ↗ · Free PDF ↗
Prognostic value of epicardial adipose tissue distribution as a complementary risk marker for major adverse cardiovascular events in diabetes.
This prospective study evaluated whether epicardial adipose tissue (EAT) volume and spatial distribution measured by cardiac magnetic resonance (CMR) better predicts major adverse cardiovascular events (MACE) than BMI, waist–hip ratio (WHR), and visceral adiposity index (VAI) in 1071 adults with diabetes mellitus. The key finding was that increased EAT (including its distribution) provided complementary prognostic information for MACE beyond general obesity metrics. This supports using CMR-derived EAT as an additional cardiovascular risk marker to refine MACE prediction in people with diabetes.
Qiao S, Liu C, Ma Y et al. · Scientific reports · (2026) · View on PubMed ↗ · Free PDF ↗
Extra-Mitral Abnormalities in Non-Syndromic Mitral Valve Prolapse assessed by Cardiovascular Magnetic Resonance.
This retrospective case-control study used cardiovascular magnetic resonance (CMR) to investigate systemic morpho-functional features consistent with connective tissue alterations in 120 non-syndromic mitral valve prolapse (MVP) patients without more than mild regurgitation and without confounding conditions such as bicuspid aortic valve or known syndromic connective tissue disease. The key finding was the presence of extra-mitral abnormalities on CMR, suggesting systemic involvement beyond the mitral leaflets in non-syndromic MVP. Clinically, these CMR findings may help identify MVP patients who warrant broader cardiovascular assessment for connective-tissue–related phenotypes.
Figliozzi S, Stankowski K, Donia D et al. · The Canadian journal of cardiology · (2026) · View on PubMed ↗
Generated automatically on July 20, 2026. Covers PubMed articles published July 13, 2026 – July 20, 2026. Summaries are AI-generated; always consult the original publication for clinical or research decisions.