What’s New in Cardiac MRI?

August 01, 2026 · 91 articles · 15 research themes · covering July 25, 2026 – August 01, 2026

Overview

This week’s cardiovascular literature is dominated by a “precision imaging” theme: researchers are pushing cardiac MRI and PET/CT beyond standard measurements toward mechanistic, quantitative, and patient-specific biomarkers. Across hypertrophic cardiomyopathy, dilated cardiomyopathy, mitral valve prolapse, aortic regurgitation, and post–myocardial infarction remodeling, multiple studies show that CMR-derived metrics (e.g., LGE/T1/ECV, feature-tracking strain, coupling indices, and microvascular obstruction phenotypes) can refine risk stratification and better predict arrhythmic or heart-failure outcomes than conventional thresholds alone. Importantly, several papers also highlight diagnostic pitfalls and modality discordance—such as ECG-based assumptions failing against CMR fibrosis reference standards, or LVEF classification differing between CMR and echocardiography—arguing for more careful, multimodality interpretation.

A second major thread is the rapid maturation of AI and accelerated imaging workflows. Studies report deep-learning reconstruction and artifact suppression for real-time or free-breathing cardiac MRI, automated segmentation for 4D flow volumetrics, and AI approaches to predict or improve image quality before scanning. Complementing this, electrophysiology-focused work uses high-density body-surface potential data and CMR-derived substrate “corridors” to connect imaging phenotypes to arrhythmia mechanisms, while PET/CT work in oncology (including immunotherapy response criteria) shows that longitudinal, whole-body metabolic trajectories and choice of response metric materially affect prognostic performance.

Finally, the digest underscores how cardiovascular disease is increasingly viewed through systemic and context lenses—ranging from infectious and autoimmune triggers of cardiac involvement, to pulmonary hypertension physiology and right-heart remodeling, to cancer therapies (radiation and cardio-oncology surveillance) and even global health determinants. Together, these studies point toward a future where imaging is not just descriptive, but integrated with biology, hemodynamics, and clinical decision-making—enabling earlier diagnosis, better phenotyping, and more tailored management.

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Cardiac Electrophysiology & Arrhythmia Risk (CMR/ECG/Mapping)

Dynamic Mode Decomposition (DMD) for Low-Latency Real-Time Cardiac MRI.

This study demonstrated dynamic mode decomposition (DMD) for low-latency real-time reconstruction in 2D real-time cardiac MRI using spiral bSSFP data. In 10 healthy adult volunteers and 6 pregnant females, DMD-based online reconstruction was evaluated against off-line spatiotemporally constrained reconstruction (STCR) and tested at two temporal resolutions. The significance is that DMD can enable faster real-time cardiac MRI reconstruction, potentially improving feasibility for time-critical imaging in both adults and fetal/maternal settings.

Yagiz E, Tasdelen B, Ozaslan IK et al. · Magnetic resonance in medicine · (2026) · View on PubMed ↗ · Free PDF ↗

Prognostic Value of Scar Spatial Properties on CMR for Major Adverse Cardiovascular Events After Myocardial Infarction.

This retrospective study evaluated whether scar spatial properties on cardiac magnetic resonance (CMR) improve prediction of major adverse cardiovascular events (MACEs) after myocardial infarction by focusing on border zone channel features quantified with ADAS 3D (BZC). Using post-MI patients with ADAS 3D post-processing confirmation of BZC, it assessed arrhythmic composite outcomes as the primary endpoint and expanded composite outcomes as secondary endpoints. The significance is that spatial characterization of the electrical conduction-relevant border zone may outperform conventional border zone measures for MACE risk prediction after MI.

Zhao X, Wang L, Chen W et al. · Academic radiology · (2026) · View on PubMed ↗

Idiopathic 2:1 AV Block With Ventriculophasic Sinus Arrhythmia in a Young Male.

This case report describes a 23-year-old male with idiopathic 2:1 atrioventricular (AV) block accompanied by ventriculophasic sinus arrhythmia, after an influenza-like presentation. The key finding was that ECG demonstrated 2:1 AV block with right bundle branch block and ventriculophasic sinus arrhythmia, while comprehensive workup excluded structural/infiltrative and other identifiable causes and exercise stress testing supported the clinical characterization. The significance is that rare conduction-physiology patterns can occur in young adults without an obvious etiology, informing differential diagnosis and evaluation strategies.

Tortorici C, Duarte G, Mark JD et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Clinical Characteristics of Multifocal PVCs Originating from the Basal Septal Region of the Left Ventricle: Anatomy, mapping and ablation.

This study examined the clinical characteristics and ablation outcomes of multifocal premature ventricular complexes (PVCs) originating from the basal septal region of the left ventricle in patients undergoing coronary venous mapping (CVM). The key finding was that despite morphological diversity, these multifocal septal PVCs could be mapped systematically to a confined basal LV septal region and targeted with ablation from the anterolateral LV ostium toward the posterior LV process. This supports a stepwise electrophysiology workflow using CVM to improve localization and treatment of complex septal PVC presentations.

Gardziejczyk P, Tertulien T, Stuckey M et al. · Heart rhythm · (2026) · View on PubMed ↗

Structural and Functional Characteristics of Cardiac MRI-Detected Corridors in Ischemic Ventricular Tachycardia.

This retrospective study evaluated whether cardiac MRI–detected corridors of ischemic ventricular tachycardia (VT) substrate correlate with electroanatomical mapping (EAM) findings and predict arrhythmogenicity and outcomes. The key finding was that corridors identified using ADAS-3D late gadolinium enhancement CMRI analysis were compared against substrate mapping with isochronal late activation mapping (ILAM) in 43 patients undergoing ischemic VT ablation. Clinically, it tests whether CMRI-derived corridor analysis can help refine VT substrate targeting and risk stratification before ablation.

Dogan M, Coteli C, Aytemir K et al. · Pacing and clinical electrophysiology : PACE · (2026) · View on PubMed ↗

Body surface potential driven personalisation of electrophysiological digital twins in hypertrophic cardiomyopathy.

The study developed body surface potential (BSP)-driven personalized electrophysiological digital twins for patients with hypertrophic cardiomyopathy (HCM) using electrocardiographic imaging (ECGI) data and multimodal clinical imaging. By integrating Bayesian model calibration, the workflow constructed patient-specific electrophysiology models that better captured inter-patient heterogeneity in ventricular electrical properties than descriptive ECGI alone. This mechanistic, personalized modelling approach could improve risk stratification for arrhythmias in HCM by linking high-density BSP measurements to underlying tissue-level electrophysiology.

Malik S, Cicci L, Qayyum A et al. · PLoS computational biology · (2026) · View on PubMed ↗ · Free PDF ↗

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Cardiac Imaging Biomarkers & Tissue Characterization (CMR T1/T2/LGE/ECV/Mapping)

Impact of Left and Right Bundle Branch Block on Left Ventricular Systolic Function and Myocardial Mechanics Assessed by Speckle-Tracking Echocardiography and Cardiac Magnetic Resonance Feature Tracking: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated how left bundle branch block (LBBB) and right bundle branch block (RBBB) affect left ventricular (LV) systolic function and myocardial mechanics in human studies, using speckle-tracking echocardiography (STE) and cardiac magnetic resonance feature tracking (CMR-FT). Across included cohorts, bundle branch block was associated with impaired conventional systolic measures and abnormal myocardial deformation/strain indices, indicating subclinical LV dysfunction beyond LVEF. These findings support using STE and CMR-FT to detect dyssynchrony-related myocardial impairment in patients with LBBB or RBBB, potentially improving risk stratification and management decisions.

Sonaglioni A, Lombardo M, Gramaglia GF et al. · Echocardiography (Mount Kisco, N.Y.) · (2026) · View on PubMed ↗

Clinical Applications of Cardiac Diffusion MRI: A Scoping Review.

This scoping review synthesized evidence from in vivo human studies on cardiac diffusion MRI, focusing on diffusion-weighted imaging (DWI) and related techniques such as cardiac diffusion tensor imaging and intravoxel incoherent motion. The review characterized the breadth of clinical applications and emerging trends through searches of MEDLINE, Embase, and Cochrane Library up to March 2025, summarizing study types, imaging methods, and reported clinical uses. By mapping where diffusion MRI is already applied and where it is heading, the review helps guide future clinical translation and research prioritization for cardiac microstructure and tissue characterization.

Vora N, Cook M, Harper L et al. · Radiology. Cardiothoracic imaging · (2026) · View on PubMed ↗

Papillary muscle fibrosis on cardiac magnetic resonance imaging: a pictorial review of causes, diagnostic challenges and practical pearls.

This pictorial review summarized causes and diagnostic pitfalls of papillary muscle fibrosis (PMF) on cardiac magnetic resonance (CMR), focusing on why PMF can be missed despite its association with ventricular arrhythmias. The key message is that careful papillary muscle assessment is required because PMF may be overlooked when papillary muscle and blood pool have similar signal intensity on late gadolinium enhancement (LGE). Clinically, improving recognition of PMF on CMR can support earlier identification of arrhythmia risk across ischaemic and non-ischaemic cardiomyopathies.

Gutierrez M, McCreavy D, Radike M · Clinical radiology · (2026) · View on PubMed ↗

Estimating the Sodium Content: A Case Series of Benign and Malignant Renal Tumours Using 23Na-MRI at 3 T.

This prospective case series applied 3T sodium MRI (23Na-MRI) to estimate sodium content in 10 patients with localized renal tumours, including renal oncocytoma, chromophobe renal cell carcinoma, and clear cell renal cell carcinoma. The study demonstrated that tumour sodium content can be quantified non-invasively and may help differentiate benign versus malignant renal tumour types. If validated, 23Na-MRI could improve early, non-invasive uro-oncology tumour subtyping and reduce reliance on invasive diagnostics.

Horvat-Menih I, Birchall JR, Zamora-Morales MJ et al. · NMR in biomedicine · (2026) · View on PubMed ↗ · Free PDF ↗

Hypertension and myocardial fibrosis: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the relationship between hypertension (HTN) and myocardial fibrosis (MF) using observational and interventional studies where MF was assessed by histology or CMR T1 mapping (including extracellular volume fraction [ECV%] and native T1). Across 39 studies totaling 45,776 participants, the analysis synthesized evidence linking HTN and/or blood pressure burden and antihypertensive treatment exposure with measures of myocardial fibrosis. The findings support HTN as a modifiable driver of myocardial fibrosis and reinforce the value of CMR T1-based fibrosis assessment in cardiovascular risk management.

Jiang J, Deng J, Dong L et al. · Clinical radiology · (2026) · View on PubMed ↗ · Free PDF ↗

Aorta and coronary artery assessment using high-contrast respiratory motion corrected and ECG-gated 3D T2-prepared GRE MRI with Dixon fat-water separation in patients with and without prior aortic root surgery at 3 T.

This CMR case series used quantitative native T1 mapping to characterize two cardiac lipomas—one papillary muscle lipoma in a 47-year-old woman and one intracavitary left ventricular lipoma in a 31-year-old Asian man. The key finding was that, despite conventional CMR fat-signal features, native T1 mapping showed markedly reduced T1 values (250 ms and 405 ms at 1.5 T), improving lesion characterization in anatomically complex or mimic-prone locations. Scientifically, it supports native T1 mapping as a quantitative adjunct for diagnosing cardiac lipomas when conventional imaging is uncertain.

Cereghetti GM, Huber LP, Todorski I et al. · European journal of radiology · (2026) · View on PubMed ↗

Impact of age, heart rate, and body surface area on myocardial native T1, T2, and extracellular volume fraction in pediatric patients at 1.5 Tesla cardiac magnetic resonance imaging.

This pediatric CMR study at 1.5 Tesla assessed how age, heart rate, and body surface area influence global myocardial native T1, T2, and extracellular volume (ECV) fraction reference values for tissue characterization. The key finding was that native T1, T2, and ECV vary systematically with physiologic covariates (including age and heart rate/body size measures), necessitating pediatric-specific reference ranges. Scientifically and clinically, these reference values improve interpretation of native T1/ECV (diffuse fibrosis) and T2 (edema) mapping in children and support more accurate CMR-based diagnosis and monitoring.

Riaza-Martin L, Escudero-Fernandez JM, Riera-Soler L et al. · Pediatric radiology · (2026) · View on PubMed ↗ · Free PDF ↗

SPACE: Pathophysiology of Platypnea-Orthodeoxia Syndrome With Aortic Aneurysm in 5 Steps.

This JACC Case Reports report describes a 47-year-old woman with platypnea-orthodeoxia syndrome in the setting of a bicuspid aortic valve and ascending aortic aneurysm, with persistent right-to-left shunting across a patent foramen ovale despite normal pulmonary vascular resistance. The key finding was that multimodal imaging showed the aneurysmal aorta displacing the cardiac axis, compressing the interatrial septum/right atrium, and—together with a prominent Eustachian valve—promoting venous flow across the foramen ovale in an upright posture. This case highlights a mechanistic, imaging-guided explanation for positional hypoxemia and supports targeted surgical management of the anatomic driver.

Hanses U, Osteresch R, Rühle S et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗

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Cardiac MRI Reconstruction, Acceleration & AI Automation

Automated whole-heart volumetrics and haemodynamics from 4D flow CMR magnitude images: development and validation of a deep learning model.

This development and validation study created and validated a deep learning model to automate whole-heart volumetrics and hemodynamics from 4D flow CMR magnitude images, using standard cine imaging as the reference. In 40 prospectively enrolled patients (PREFER-CMR registry), the model performed automated segmentation of cardiac structures from magnitude images and was validated for anatomical accuracy against conventional cine stacks. If robust, this AI approach could substantially reduce 4D flow CMR post-processing time and improve scalability of comprehensive hemodynamic assessment.

Gall A, Grafton-Clarke C, Li R et al. · European heart journal. Imaging methods and practice · (2026) · View on PubMed ↗ · Free PDF ↗

Time-resolved aortic 3D shape reconstruction from a limited number of cine 2D MRI slices.

The study evaluated feasibility and accuracy of reconstructing time-resolved, subject-specific 3D aortic geometries from a limited number of cine 2D MRI slices in 30 human subjects (19 volunteers and 11 aortic patients). It found that coupling a statistical shape model with a differentiable volumetric mesh optimization algorithm enabled accurate time-resolved 3D aortic shape reconstruction, with slice positioning first optimized on synthetic data and then tested in vivo. This supports a faster, less acquisition-intensive cardiac MRI workflow for patient-specific aortic modeling that could improve downstream hemodynamic or surgical planning.

Wolkerstorfer G, Buoso S, Schlenker R et al. · Computer methods and programs in biomedicine · (2026) · View on PubMed ↗ · Free PDF ↗

Automation Software for Transesophageal Echocardiography in Cardiac Patients: A Scoping Review.

This scoping review mapped evidence on automation software for transesophageal echocardiography (TEE) in cardiac patients, comparing automated measurements with manual measurements and summarizing validation outcomes. It found that the literature on TEE automation is heterogeneous and less established than for transthoracic echocardiography, with identified evidence gaps across tools and validation approaches. The review supports targeted future studies to standardize TEE automation validation and improve reproducibility and efficiency in peri-procedural cardiac imaging.

Ghijselings I, Elst J, Rex S et al. · Journal of cardiothoracic and vascular anesthesia · (2026) · View on PubMed ↗

Free-Breathing 3D Whole Heart and Aorta Cine MRI Without Contrast Agent-Comparison to Clinical Standard.

This prospective study evaluated a free-breathing 3D whole-heart and aorta cine MRI technique without a contrast agent at 1.5 T in 24 healthy volunteers. The key finding was that the proposed non-contrast, single-acquisition free-breathing 3D cine approach can provide simultaneous assessment of cardiac function and aortic anatomy while avoiding multiple breath-holds required by conventional multi-breath-hold 2D cine plus 3D MR angiography protocols. This is significant because it may broaden access and improve feasibility of cardiac MRI in patients with limited breath-hold capacity.

Chen R, Lu H, Cernicanu A et al. · Journal of magnetic resonance imaging : JMRI · (2026) · View on PubMed ↗ · Free PDF ↗

Pre-Imaging Clinical Factors Associated With Cardiac MR Image Quality Using Large Language Model-Enabled Data Extraction.

This retrospective study assessed whether pre-imaging clinical information extracted using a large language model (LLM) is independently associated with cardiac MR image quality in 1006 adult patients undergoing clinical cardiac MRI. It found that LLM-extracted pre-imaging factors were associated with image quality categories (excellent to nondiagnostic) across multiple protocol types (cine, black blood, MR angiogram, and late gadolinium enhancement) on 1.5 T and 3 T scanners. The result is clinically important because it suggests an AI-enabled way to predict and potentially mitigate poor image quality before scanning, reducing repeat exams.

Yu H, Bondarenko M, Nowroozi A et al. · Journal of magnetic resonance imaging : JMRI · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗

Poor R-wave progression fails to detect anterior myocardial fibrosis in MESA.

This analysis of Multi-Ethnic Study of Atherosclerosis (MESA) participants tested whether poor R-wave progression (PRWP) on 12-lead ECG identifies anterior myocardial fibrosis on modern CMR. Using prespecified PRWP criteria (RV3 ≤ 3 mm with RV3 > RV2) and a sensitivity analysis (Zema MI criterion), the study found that PRWP failed to detect anterior-wall fibrosis by the strict CMR reference standard. Scientifically, it challenges older ECG-based assumptions and supports using CMR rather than PRWP alone to evaluate anterior myocardial fibrosis.

de Alencar JN, Morales PAS · International journal of cardiology · (2026) · View on PubMed ↗

Supporting transformer-based cardiac MRI segmentation with text-to-image controllable diffusion pipelines.

This computational study developed a transformer-based cardiac MRI segmentation support method using text-to-image controllable diffusion pipelines to generate synthetic cardiac MRI scans with segmentation labels. The key finding is that combining Low-Rank Adaptation (LoRA) for pathology-aware label map generation with ControlNet for semantic and spatial conditioning enables creation of fully annotated synthetic datasets aligned with cardiac anatomy. Scientifically, it offers a scalable way to augment limited labeled datasets to improve segmentation model training for cardiac MRI.

Fouadi H, Kas M, Ruichek Y et al. · Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · (2026) · View on PubMed ↗

Rapid online deep artifact suppression for real-time spiral bSSFP CMR with blipped-CAIPI simultaneous multi-slice imaging at 1.5 T.

This technical study investigated rapid online deep artifact suppression for real-time spiral bSSFP cardiac MRI using blipped-CAIPI simultaneous multi-slice (SMS) imaging at 1.5 T in healthy volunteers. The key finding was that a 3D U-Net–based deep artifact suppression approach enabled online reconstruction of real-time spiral SMS bSSFP data, addressing limitations of iterative reconstructions for non-Cartesian trajectories. This is significant because it can shorten free-breathing functional CMR acquisition while preserving real-time usability for cardiac assessment.

Åkesson J, Dragonu I, Heiberg E et al. · Magnetic resonance imaging · (2026) · View on PubMed ↗ · Free PDF ↗

High Resolution Isotropic ‘Pseudo’ 3D Cine imaging with Automated Segmentation using Concatenated 2D Real-time Imaging and Deep Learning.

This study developed and evaluated deep learning–based automated segmentation to generate an isotropic “pseudo” 3D cine dataset by concatenating stacks of 2D free-breathing real-time cines in pediatric and congenital heart disease contexts. The key finding was that multiple deep learning models (including interslice signal correction, interslice respiratory correction, and slice-direction super-resolution) could produce a fully segmented isotropic pseudo-3D cine representation from real-time 2D inputs. Scientifically, it advances CMR reconstruction methods that may reduce breath-hold/static 3D requirements and improve functional imaging in children and patients with congenital heart disease.

Wrobel M, Yao T, Campbell R et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗

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Multimodal Imaging for Myocarditis & Inflammatory Heart Disease

Molecular mechanisms of coronary microembolization-induced MINOCA.

This basic research article investigated the molecular mechanisms by which coronary microembolization (CME) can drive myocardial infarction with non-obstructive coronary arteries (MINOCA), a condition often diagnosed late because cardiac MRI is typically performed days after the index event. The authors highlight that incomplete understanding of CME’s molecular pathways limits rapid diagnostic tools and targeted therapy development for MINOCA. Clarifying CME biology could enable earlier, mechanism-based diagnosis and more specific treatment strategies for MINOCA patients.

Iske J, Thau H, Mesfin JM et al. · Basic research in cardiology · (2026) · View on PubMed ↗ · Free PDF ↗

Imaging signatures of eosinophilic granulomatosis with polyangiitis-related myocarditis: A case report.

This case report studied a 23-year-old man with asthma and persistent hypereosinophilia who was diagnosed with eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome) with renal and neurological involvement. Cardiac MRI identified myocarditis-related abnormalities (eosinophilic infiltration pattern) that supported the diagnosis of cardiac involvement. The report is significant because it underscores cardiac MRI as the most sensitive noninvasive tool for detecting suspected Churg-Strauss myocarditis and enabling timely immunosuppression adjustment.

Lamassab NEH, Merimi I, Nabila I et al. · Radiology case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Cardiac MRI unveils the hidden storm: Myocarditis-induced ventricular tachycardia in a young patient with a structurally normal heart.

This case report studied a 37-year-old previously healthy man presenting with hemodynamically unstable ventricular tachycardia and elevated troponin but normal coronary arteries and preserved left ventricular systolic function on echocardiography. Cardiac MRI revealed subepicardial late gadolinium enhancement and myocardial edema, establishing acute myocarditis as the arrhythmogenic substrate. The clinical significance is that CMR can unmask myocarditis in young patients with structurally normal hearts when arrhythmias mimic idiopathic fascicular ventricular tachycardia.

Alkhanafsa M, Aloqaily M, Ababneh R et al. · Radiology case reports · (2026) · View on PubMed ↗ · Free PDF ↗

18F-fluorodeoxyglucose positron emission tomography and rest myocardial perfusion imaging in non-granulomatous myocarditis.

This multicenter prospective observational feasibility study evaluated the diagnostic performance of combined 18F-fluorodeoxyglucose (FDG) PET/CT and rest myocardial perfusion imaging (rMPI) in non-granulomatous myocarditis, compared with cardiac MRI and with endomyocardial biopsy (EMB) or adjudicated clinical diagnosis as reference standards. The key finding (as assessed in the study) was the feasibility and diagnostic utility of integrating FDG-PET/CT with rMPI for suspected myocarditis. The clinical significance is that a combined metabolic-and-perfusion imaging approach may improve noninvasive diagnosis of myocarditis when EMB is unavailable or limited.

Lucinian YA, Martineau P, Harel F et al. · European journal of nuclear medicine and molecular imaging · (2026) · View on PubMed ↗

Myocardial infarction with non-obstructive coronary arteries: A multimodal imaging approach to diagnosis and etiology-targeted therapy.

This article reviewed myocardial infarction with non-obstructive coronary arteries (MINOCA), a heterogeneous diagnosis affecting about 5–15% of acute MI presentations, and discussed multimodal imaging strategies to determine etiology. It emphasized that systematic exclusion of non-ischemic mimics and identification of ischemic mechanisms using intracoronary optical coherence tomography and intravascular ultrasound can enable etiology-targeted therapy rather than therapeutic inertia. The clinical significance is improved diagnostic precision and more appropriate, mechanism-based management for MINOCA patients.

Abdu FA · Current problems in cardiology · (2026) · 1 citations · View on PubMed ↗

Losartan and prednisolone for post-COVID syndrome and cardiac inflammation: a randomized, double-blind, placebo-controlled trial.

This randomized, double-blind, placebo-controlled trial (Myoflame-19) studied 279 participants with post-COVID syndrome and inflammatory cardiac involvement defined by cardiovascular magnetic resonance, comparing losartan plus prednisolone versus matched placebos for 16 weeks. The primary endpoint—change in left ventricular ejection fraction—was neutral, with no meaningful between-group difference (reported as 0.7). Clinically, the results suggest that targeting inflammation/endothelial dysfunction with losartan and prednisolone does not improve LV systolic function in this CMR-defined post-COVID inflammatory population.

Puntmann VO, Nagel E, Beitzke D et al. · Nature communications · (2026) · View on PubMed ↗

Post-traumatic pericarditis following penetrating injury to the heart: a case report.

This case report describes a 22-year-old man who developed post-traumatic pericarditis progressing to transient constrictive pericarditis after a penetrating stab wound to both ventricles. The key finding was that multimodal imaging was crucial for diagnosis and follow-up as the post-cardiac injury syndrome evolved, despite initial evaluation showing no fever and stable vitals. The clinical significance is that multimodal imaging can detect and characterize rare post-traumatic inflammatory pericardial syndromes and their progression to constriction.

Ekhelikar S, Chukwudi I, Lewis G et al. · The international journal of cardiovascular imaging · (2026) · View on PubMed ↗

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Coronary Microvascular Dysfunction & Post-MI Microvascular Obstruction

Reduced regadenoson dose using heart rate-targeted titration in paediatric stress perfusion CMR.

This retrospective study evaluated heart rate–targeted incremental regadenoson titration in 31 paediatric patients (29 technically successful) undergoing stress perfusion cardiac magnetic resonance (CMR) for known or suspected coronary artery disease. Targeting a ≥20% heart-rate increase achieved individualized dosing with feasibility and safety while maintaining diagnostic performance compared with weight-based fixed dosing. The approach may reduce excessive regadenoson exposure in children and improve the precision of pharmacologic stress CMR protocols.

Quail MA, Tann O, Linton R et al. · European heart journal. Imaging methods and practice · (2026) · View on PubMed ↗ · Free PDF ↗

Prognostic Implications of Coronary Microvascular Dysfunction in ST-Elevation Myocardial Infarction by Obesity Status.

This multicentre prospective cohort study assessed coronary microvascular dysfunction (CMD) using the angiography-derived index of microcirculatory resistance (angio-IMR) in 497 ST-elevation myocardial infarction (STEMI) patients stratified by obesity category (BMI <24, 24–28, and ≥28 kg/m2). CMD prevalence was comparable across BMI groups, while the study tested whether CMD (defined as angio-IMR >40 U) predicted long-term cardiovascular outcomes differently by obesity status. The results are significant because they clarify how obesity modifies (or does not modify) the prognostic impact of angiography-based CMD assessment after STEMI.

Guo Q, Guo Y, Shi S et al. · Diabetes, obesity & metabolism · (2026) · View on PubMed ↗ · Free PDF ↗

Prognostic impact of persistent microvascular obstruction on cardiac magnetic resonance after STEMI: A systematic review and meta-analysis.

This systematic review and meta-analysis compared prognosis in STEMI patients undergoing primary PCI who had persistent microvascular obstruction (MVO) versus transient MVO or no MVO, using follow-up cardiac magnetic resonance (CMR) classification. Persistent MVO was associated with worse outcomes than transient MVO or absence of MVO across included cohort studies. Clinically, CMR-defined persistent MVO could serve as a risk stratifier to guide intensity of post-STEMI management.

Gadelmawla AF, Taha AM, Alkuwaiti FA et al. · International journal of cardiology · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗

Rethinking post-infarction remodelling: identification and validation of data-driven cardiac MRI phenotypes for risk stratification.

This prospective longitudinal study investigated data-driven cardiac MRI phenotypes of adverse left ventricular remodeling after reperfused ST-elevation myocardial infarction (STEMI) using CMR at <7 days and at 6 months in a derivation cohort (n=337) and independent validation cohort (n=190). It found that unsupervised, longitudinal CMR-derived remodeling phenotypes had better prognostic relevance for outcomes than conventional adverse remodeling definitions based on changes in left ventricular end-diastolic volume index and ejection fraction. The significance is that phenotype-based CMR risk stratification could improve prediction of post-infarction outcomes and guide more personalized follow-up and therapy.

Xiang JY, Wu J, Zhao Y et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗

SGLT2 Inhibitor on Infarct Size and LV Remodeling by CMR in Patients With AMI.

This prospective, open-label randomized controlled trial studied whether sodium-glucose cotransporter 2 (SGLT2) inhibitor therapy affects infarct size and left ventricular (LV) remodeling measured by cardiac magnetic resonance (CMR) in patients after acute myocardial infarction (AMI) treated with percutaneous coronary intervention (PCI). The key finding was the trial’s assessment of myocardial injury and remodeling endpoints using CMR to clarify potential cardioprotective mechanisms of SGLT2 inhibitors post-AMI. Scientifically, it aims to link SGLT2 therapy to measurable CMR changes that could explain improved outcomes seen in prior large randomized trials.

Choi KH, Lee SH, Kim SM et al. · JACC. Cardiovascular interventions · (2026) · View on PubMed ↗

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Valvular Heart Disease Prognosis (Aortic Regurgitation/Mitral Valve Prolapse)

Effects of a Fasting-mimicking Diet on MRI-assessed Cardiac Structure and Function in Participants with Type 2 Diabetes.

In a secondary analysis of the prospective Fasting In diabetes Treatment trial (NCT03811587), adults with type 2 diabetes (T2D) were randomized to a monthly 5-day fasting-mimicking diet (FMD) versus usual care and underwent 3.0T cardiac MRI at baseline, 6 months, and 12 months. The study assessed whether the FMD altered LV geometry and systolic function from 2D cine images and diastolic function from 4D flow MRI. If beneficial effects were observed, they would provide MRI-based evidence that periodic fasting-mimicking dietary interventions can modify cardiac structure/function in T2D, informing cardiometabolic prevention strategies.

Chen R, Westenberg JJM, van den Burg EL et al. · Radiology. Cardiothoracic imaging · (2026) · View on PubMed ↗

Association between Cardiac MRI-derived Global Longitudinal Strain and Clinical Outcomes in Chronic Aortic Regurgitation.

This multicenter retrospective study examined whether cardiac MRI-derived left ventricular global longitudinal strain (LV GLS) measured by cine MRI feature tracking predicts outcomes in patients with isolated chronic moderate-to-severe aortic regurgitation (AR). Using multivariable Cox proportional hazards models with endpoints of all-cause death or heart failure-related hospitalization, the key finding was that LV GLS had prognostic value independent of standard measures such as LV ejection fraction (LVEF) and volumes. Clinically, incorporating MRI feature-tracking GLS could improve risk stratification for chronic AR patients and help identify those who may benefit from earlier intervention.

Hashimoto G, Enriquez-Sarano M, Koike H et al. · Radiology. Cardiothoracic imaging · (2026) · View on PubMed ↗

Cardiac Magnetic Resonance for the Prediction of Arrhythmic Events in Mitral Valve Prolapse: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis evaluated CMR biomarkers—late gadolinium enhancement (LGE), mitral annular disjunction (MAD), and systolic curling—for predicting arrhythmic events in 1,994 patients with mitral valve prolapse (MVP) across 15 studies. The key finding was that all three biomarkers were significantly associated with increased arrhythmic risk, with pooled relative risks around 1.5–1.8 depending on the marker (and moderate heterogeneity). Clinically, it supports using CMR-derived LGE, MAD, and systolic curling to refine arrhythmic risk stratification in MVP patients.

Papanastasiou CA, Kampaktsis PN, Papalamprakopoulou Z et al. · The American journal of cardiology · (2026) · View on PubMed ↗

Left ventricular global longitudinal strain improves risk stratification in chronic aortic regurgitation.

This retrospective cohort study assessed whether cardiac magnetic resonance (CMR) feature-tracking derived left ventricular global longitudinal strain (FT-LVGLS) improves risk stratification in 385 patients with chronic moderate-to-severe aortic regurgitation (AR) and minimal/no symptoms. The key finding was that FT-LVGLS provided prognostic value for adverse outcomes and added incremental predictive information beyond the 2025 ESC/EACTS Class I/IIb surgical indication parameters. Scientifically and clinically, it supports incorporating FT-LVGLS into CMR-based evaluation to better identify AR patients at higher risk who may benefit from closer management or earlier intervention.

Li B, Liu Y, Dai L et al. · European heart journal. Cardiovascular Imaging · (2026) · 1 citations · View on PubMed ↗

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Heart Failure & Cardiomyopathy Phenotyping/Prognosis (DCM/HCM/Fontan/Other)

Three-dimensional Mapping of Fibrosis Distribution in Desmoplakin Cardiomyopathy from Cardiac MRI.

This retrospective cardiac MRI study in patients with desmoplakin cardiomyopathy used late gadolinium enhancement (LGE) to identify fibrosis and mapped it onto 3D ventricular geometry using universal ventricular coordinates. By reconstructing 3D ventricular models from cine MRI and aligning fibrosis distribution to a common reference framework, the investigators enabled spatial comparison of fibrotic patterns across mild, moderate, and severe disease categories. The resulting high-resolution fibrosis maps could improve understanding of disease progression in desmoplakin cardiomyopathy and support more precise, spatially informed risk assessment.

Jilberto J, McManus B, Moghrabi A et al. · Radiology. Cardiothoracic imaging · (2026) · View on PubMed ↗

Apical hypercontractility mitigates impaired diastolic filling and lower intraventricular haemodynamic forces in human bed rest.

This experimental physiology study used cardiac magnetic resonance imaging in 24 healthy participants before, during, and after 60 days of strict head-down tilt bed rest (AGBRESA) to assess how apical hypercontractility relates to impaired diastolic filling and intraventricular haemodynamic forces. The authors found that apical hypercontractility mitigated the bed-rest–induced deterioration in diastolic filling and reduced intraventricular haemodynamic forces. These results suggest a compensatory regional contractility mechanism that may protect cardiac function early during prolonged inactivity.

Rabineau J, Al-Darwish F, Mulder E et al. · Experimental physiology · (2026) · View on PubMed ↗ · Free PDF ↗

Quantitative Assessment of Myocardial Velocity and Dyssynchrony in Fontan Circulation Using MR Tissue Phase Mapping.

This prospective study used MR tissue phase mapping (TPM) to quantify myocardial motion velocity and dyssynchrony in the functional ventricle of 28 Fontan patients and 42 matched controls. TPM-derived metrics across longitudinal (Vz), radial (Vr), and circumferential (Vphi) directions showed altered motion velocities and dyssynchrony indices in Fontan physiology, linking myocardial motion to cardiac function. These quantitative imaging biomarkers may improve assessment of mechanical dysfunction and guide monitoring in Fontan patients.

Lu XZ, Weng KP, Wu MT et al. · NMR in biomedicine · (2026) · View on PubMed ↗

Aspirin therapy after heart transplantation is associated with higher myocardial perfusion reserve assessed by cardiovascular magnetic resonance imaging.

This multicenter observational study investigated whether aspirin therapy after heart transplantation is associated with myocardial perfusion reserve, using cardiovascular magnetic resonance (CMR) in Swedish heart-transplant recipients undergoing CMR and coronary angiography. The key finding was that aspirin therapy after heart transplantation was associated with higher myocardial perfusion reserve, a CMR marker used to reflect cardiac allograft vasculopathy (CAV). Clinically, this suggests aspirin may preserve allograft microvascular function and could influence long-term CAV risk assessment in transplant care.

Jablonowski R, Löfman IH, Andersson HB et al. · JHLT open · (2026) · View on PubMed ↗ · Free PDF ↗

Prognostic Value of a Cardiac Magnetic Resonance-Derived Left Atrioventricular Coupling Index From Routine Cine Images in Dilated Cardiomyopathy: A Multicenter Study.

This multicenter retrospective study evaluated a cardiac MRI-derived left atrioventricular coupling index (LACI) from routine cine images for prognostic prediction in 403 patients with dilated cardiomyopathy (DCM). The key finding was that LACI provided prognostic value for adverse outcomes and offered incremental utility beyond conventional markers such as left ventricular ejection fraction (LVEF) and late gadolinium enhancement (LGE). This is significant because it proposes a practical, cine-based CMR metric to improve risk stratification in DCM without requiring additional specialized sequences.

Jiang YJ, Hou XC, Tao J et al. · Journal of magnetic resonance imaging : JMRI · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗

Comparison of Left Ventricular Ejection Fraction and Disease Classification by Cardiac Magnetic Resonance and Echocardiography.

This retrospective study compared left ventricular ejection fraction (LVEF) measured by cardiac magnetic resonance (CMR) versus transthoracic echocardiography (TTE) in patients who underwent both within 1 week, and examined determinants of discordance in clinical classification using ESC heart failure thresholds (50% and 35%). The key finding was that LVEF values and resulting heart-failure category assignment could differ between CMR and TTE, with measurable factors driving discordance. Scientifically and clinically, it supports careful interpretation of LVEF across modalities to reduce misclassification that could affect management decisions.

Le Y, An J, Liang L et al. · The American journal of cardiology · (2026) · View on PubMed ↗

Cardiac magnetic resonance tissue characterization in endurance athletes with paroxysmal atrial fibrillation phenotype (PAFIYAMA).

This observational cross-sectional study used cardiac magnetic resonance (CMR) tissue characterization to investigate myocardial substrate in endurance athletes with a paroxysmal atrial fibrillation phenotype (PAFIYAMA), comparing 22 PAFIYAMA athletes to 41 controls. The key finding (from the study’s CMR tissue characterization results) was that the myocardial abnormalities underlying the AF-related functional phenotype could be detected/characterized using CMR approaches such as late gadolinium enhancement and related tissue metrics. This is significant because it links AF phenotype in athletes to specific myocardial tissue features, informing risk assessment and mechanistic understanding.

Garatachea N, Echevarría-Polo M, Hernández-Vicente A et al. · International journal of cardiology · (2026) · View on PubMed ↗ · Free PDF ↗

Interatrial block in hypertrophic cardiomyopathy: Associations with left atrial remodeling and adverse atrial outcomes.

This multicenter cardiac magnetic resonance (CMR)-based study assessed interatrial block (IAB), defined by P-wave duration >120 ms, in 259 hypertrophic cardiomyopathy (HCM) patients without prior atrial fibrillation or stroke, relating IAB to left atrial (LA) remodeling and adverse atrial outcomes. The key finding is that IAB in HCM is associated with specific morphofunctional LA remodeling features measured by CMR and carries prognostic value for future atrial events. Clinically, defining IAB using ECG criteria alongside CMR LA phenotyping may help identify HCM patients at higher risk for atrial fibrillation and related complications.

Anmad-Shihadeh LA, Teis A, Sabate M et al. · Heart rhythm · (2026) · 1 citations · View on PubMed ↗

Disease penetrance and phenotypic spectrum of desmoplakin variant carriers in the population.

This population-based genetic study used exome sequencing data from 200,580 UK Biobank participants to estimate disease penetrance and phenotypic spectrum of desmoplakin (DSP) variant carriers, stratifying variants by predicted deleterious (pDel), predicted loss of function (pLOF), and ClinVar classifications. The key finding is that DSP variant carriers show measurable penetrance with a broader phenotypic spectrum than may be captured by existing diagnostic criteria for DSP-mediated arrhythmogenic cardiomyopathy. Clinically, these penetrance estimates can refine risk counseling, improve case-finding strategies, and guide surveillance intensity for individuals carrying DSP variants.

Gurumoorthi M, Dabbagh GS, Wolfe R et al. · Heart rhythm · (2026) · View on PubMed ↗ · Free PDF ↗

Indications, protocols, and interpretation of cardiovascular imaging for the evaluation and management of athletes. A Clinical Consensus Statement of the European Association of Preventive Cardiology (EAPC) and the European Association of Cardiovascular Imaging (EACVI) of the European Society of Cardiology (ESC). Part 2-Cardiovascular Magnetic Resonance, Cardiac CT and Nuclear Imaging.

This European clinical consensus statement studied how to use cardiovascular imaging modalities to evaluate and manage athletes, focusing on cardiovascular magnetic resonance (CMR), cardiac computed tomography (CT), and nuclear imaging. It found that a multimodality imaging strategy is recommended because each technique provides complementary information to distinguish physiological athlete remodeling from pathology and to guide risk stratification. Clinically, the guidance supports standardized indications, protocols, and interpretation for advanced imaging in sports cardiology to improve detection of exercise-related adverse event risk.

Maestrini V, Gati S, D’Ascenzi F et al. · European heart journal. Cardiovascular Imaging · (2026) · 2 citations · View on PubMed ↗

Indications, protocols, and interpretation of cardiovascular imaging for the evaluation and management of athletes: a clinical consensus statement of the European Association of Preventive Cardiology (EAPC) and the European Association of Cardiovascular Imaging (EACVI) of the ESC: Part 1-Exercise imaging.

This European clinical consensus statement studied exercise imaging—especially exercise stress echocardiography (ESE)—for evaluating cardiovascular function in athletes. It concluded that ESE is pivotal for assessing cardiac reserve, unmasking concealed cardiomyopathies, and stratifying risk in both competitive and recreational athletes. The significance is practical: it provides standardized indications, protocols, and interpretation to reduce misclassification of normal training adaptations as disease.

D’Ascenzi F, Sanz-de la Garza M, Maestrini V et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗ · Free PDF ↗

Phenotype, genotype and prognosis of apical hypertrophic cardiomyopathies: a French multicentric cohort.

This French multicenter cohort study evaluated phenotype, genotype, and prognosis in 208 patients with apical hypertrophic cardiomyopathy (ApHCM) from five centers, compared with 419 patients with non-apical HCM, using echocardiography, cardiac magnetic resonance, genetic testing, and follow-up. After excluding patients with Fabry disease (n=6) and amyloidosis (n=1), the study characterized ApHCM-specific genetic and clinical patterns and assessed prognostic differences versus non-apical HCM. The findings are clinically important because they refine genotype–phenotype understanding and prognosis in ApHCM while emphasizing the need to exclude mimicking genetic/infiltrative causes.

Martel H, Lucas C, Benjelloun H et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗

Integrated Left Ventricular Mass and Left Atrial Function for Prediction of Cardiovascular Outcomes: The Multi-Ethnic Study of Atherosclerosis (MESA).

This study in the Multi-Ethnic Study of Atherosclerosis (MESA) evaluated whether a CMR-derived left ventricular (LV) mass-to-left atrial (LA) strain ratio identifies early atrioventricular mechanical uncoupling and predicts cardiovascular events, using CMR data from Exam 1 (2000–2002) and Exam 5 (2010–2012). The key finding was that the LV mass-to-LA strain ratio (indexed LV mass divided by peak LA strain) reflects physiologic imbalance between LV hypertrophy and LA deformation and is associated with subsequent cardiovascular outcomes. Clinically, this provides a CMR-based quantitative marker for earlier detection of atrioventricular uncoupling and atrial myopathy before overt structural disease.

Salameh E, Hoballah M, Ebrahimihoor E et al. · American journal of physiology. Heart and circulatory physiology · (2026) · View on PubMed ↗

Midventricular Hypertrophic Cardiomyopathy With Apical Aneurysm Presenting as Persistent ST-Segment Elevation Mimicking Acute Myocardial Infarction.

This case report describes a 62-year-old woman presenting with persistent ST-segment elevation mimicking acute myocardial infarction, ultimately diagnosed with midventricular hypertrophic cardiomyopathy (HCM) with a left ventricular apical aneurysm. The key finding was that coronary angiography showed no obstructive disease and cardiac magnetic resonance/echocardiography demonstrated midcavity systolic obstruction with an apical aneurysm as the nonischemic substrate for the ECG pattern. Scientifically and clinically, it emphasizes that persistent ST elevation can reflect structural cardiomyopathy rather than coronary occlusion, guiding appropriate diagnostic pathways.

Kyvetos A, Liatakis I, Niarchou P et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Investigating Biventricular Intracardiac Flow Remodeling in Marathon Athletes With 4D Flow Cardiac MRI.

This study investigated biventricular intracardiac flow remodeling in marathon athletes using 4D flow cardiac MRI and examined associations with conventional measures of exercise-induced cardiac remodeling. The key finding was that 4D flow MRI can quantify ventricular flow components that may serve as complementary hemodynamic biomarkers for distinguishing exercise-induced remodeling from early cardiomyopathy. Clinically and scientifically, it supports the use of intracardiac flow metrics as novel imaging biomarkers for characterizing athletic cardiac adaptation.

Tang M, Ren W, Liu G et al. · Journal of magnetic resonance imaging : JMRI · (2026) · View on PubMed ↗

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Pulmonary Hypertension & Right-Heart Hemodynamics

A minimally invasive pre-operative measure of total pulmonary resistance is associated with early adverse outcomes following total cavopulmonary connection.

In children undergoing staged single-ventricle palliation, this study developed a minimally invasive pre-operative estimate of total pulmonary resistance (TPR) at the bidirectional cavopulmonary connection (BCPC) stage using jugular venous pressure as a surrogate for central venous pressure (CVP) and evaluated whether it predicts early adverse outcomes after total cavopulmonary connection (TCPC). Higher TPR was associated with early Fontan failure (EFF: death, TCPC take-down, emergency fenestration, or mechanical circulatory support within 6 months) and with prolonged post-operative ICU stay (>14 days). This provides a potentially practical hemodynamic biomarker to identify higher-risk patients before TCPC and guide perioperative planning.

Nadarajan N, Muthurangu V, Quail MA · European heart journal. Imaging methods and practice · (2026) · View on PubMed ↗ · Free PDF ↗

Right ventricular longitudinal function is associated with exercise capacity in pre-capillary pulmonary hypertension: a multimodality imaging study.

This multimodality imaging study assessed right ventricular (RV) longitudinal function in 49 patients with pre-capillary pulmonary hypertension (PHprecap) and related it to exercise capacity measured by 6-minute walk distance (6MWD). RV longitudinal dysfunction quantified by cardiac magnetic resonance (CMR) (RVEF/longitudinal measures) and echocardiography-derived indices (e.g., FWSECHO/FACECHO) showed significant associations with reduced exercise capacity. The results emphasize that RV longitudinal performance—measured by echo and CMR—tracks functional limitation in PHprecap, supporting its use for more refined prognostic assessment beyond NT-proBNP and risk strata.

Jumatate R, Labaf A, Ingvarsson A et al. · European heart journal. Imaging methods and practice · (2026) · View on PubMed ↗ · Free PDF ↗

Determinants of Abnormal Pulmonary Vasodilatory Response With Exercise in HFpEF: Pulmonary Vascular-Left Atrial Axis Abnormalities.

In a two-step invasive cardiopulmonary exercise testing study of 164 participants (80 HFpEF, 57 pre-capillary PH, 27 non-cardiac dyspnea), the investigators defined an unfavorable exercise pulmonary vascular resistance (PVR) response in HFpEF as exercise PVR >1.74 Woods units with a <22% decrease in PVR during exercise. The key finding was that specific pulmonary vascular–left atrial axis abnormalities were associated with this unfavorable exercise PVR pattern, identifying high-risk correlates for impaired pulmonary vasodilatory reserve. Scientifically and clinically, these results link exercise-induced pulmonary hemodynamic failure to right-heart risk in HFpEF and suggest targets for future mechanistic therapies.

Garcia-Arango M, Kristo A, El Shaer A et al. · Comprehensive Physiology · (2026) · View on PubMed ↗ · Free PDF ↗

Right ventricular remodeling and circulating metabolic profiles of patients with chronic thromboembolic pulmonary hypertension before and after pulmonary endarterectomy.

This prospective study enrolled 10 patients with chronic thromboembolic pulmonary hypertension (CTEPH) undergoing pulmonary endarterectomy (PEA) and 10 control patients with normal RV function, measuring right ventricular (RV) remodeling before and after PEA. It combined longitudinal RV imaging (including echocardiography and cardiac MRI) with RV histology and circulating metabolic profiling (18F-labeled imaging was mentioned in methods) to characterize changes in RV adaptation and identify potential biomarker-linked metabolic signatures. The findings aim to improve phenotyping of RV reverse remodeling after PEA, enabling biomarker-driven hypothesis generation for future mechanistic and therapeutic studies.

Guimaron S, Mercier J, Hautbergue T et al. · JHLT open · (2026) · View on PubMed ↗ · Free PDF ↗

Vascular compliance phenotyping in pulmonary arterial hypertension (a PVDOMICS study).

This analysis from the PVDOMICS study evaluated vascular compliance phenotyping in adults with World Symposium Group 1 pulmonary arterial hypertension, deriving pulmonary arterial compliance from right heart catheterization measurements. The key finding was that compliance relates to cardiac morphology and exercise metrics and is associated with mortality risk within a population otherwise similar in resistive afterload. Clinically, it positions catheter-derived pulmonary arterial compliance as a potential prognostic marker and helps define phenotypic drivers of compliance impairment in PAH.

Wilson TG, Oppegard L, Pi H et al. · JHLT open · (2026) · View on PubMed ↗ · Free PDF ↗

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Cardiac Amyloidosis & Other Infiltrative/Storage Diseases

Cardiac characteristics of Chinese patients with Danon disease associated with LAMP2 p.Leu325fs variants.

This retrospective study characterized the cardiac phenotype of Danon disease in nine Chinese patients carrying the LAMP2 frameshift variant p.Leu325fs (a premature termination variant causing loss of functional LAMP2 and lysosomal dysfunction). The key finding was that p.Leu325fs–associated Danon disease has distinct cardiac characteristics that refine genotype–phenotype understanding for this specific LAMP2 variant. Defining the cardiac implications of p.Leu325fs can improve prognostication and clinical management for genetically confirmed Danon disease.

Yin K, Li Y, Zhao H et al. · International journal of cardiology. Heart & vasculature · (2026) · View on PubMed ↗ · Free PDF ↗

Quantitative 99mTc-PYP SPECT/CT at 90 minutes improves diagnostic stratification in transthyretin cardiac amyloidosis.

This retrospective single-center study evaluated whether quantitative 99mTc-PYP SPECT/CT at 90 minutes post-injection improves diagnostic stratification for transthyretin cardiac amyloidosis (ATTR-CM) beyond standard planar imaging at 60 and 180 minutes. The key finding was that adding quantitative 90-minute SPECT/CT increased diagnostic specificity/stratification, particularly in patients with Perugini score 1 where planar imaging is often insufficient. Scientifically and clinically, it supports an optimized imaging protocol to better classify suspected ATTR-CM and reduce indeterminate results.

Nazerani-Zemann T, Stanzel S, Weitzer F et al. · European journal of nuclear medicine and molecular imaging · (2026) · View on PubMed ↗ · Free PDF ↗

Bridging Diagnostic Gaps in AL Cardiac Amyloidosis: The Emerging Role of 68 Ga-FAPI PET/CT.

This case report describes diagnostic workup in a 56-year-old man with suspected AL cardiac amyloidosis where conventional imaging and endomyocardial biopsy (EMB) were inconclusive and 99mTc-pyrophosphate scintigraphy was equivocal. The key finding is that 68Ga-FAPI-46 PET/CT showed intense myocardial uptake, prompting repeat bone marrow biopsy that confirmed AL amyloidosis. Scientifically and clinically, the report highlights 68Ga-FAPI PET/CT as an emerging tool to bridge diagnostic gaps when biopsy and standard imaging are discordant in suspected AL cardiac amyloidosis.

Kumar SA, Goyal H, Ahmed AS et al. · Clinical nuclear medicine · (2026) · View on PubMed ↗ · Free PDF ↗

Wild-Type Transthyretin Amyloid Cardiomyopathy With Positive 18F-FDG/13N-Ammonia Cardiac Positron Emission Tomography.

This case report studied an 85-year-old man with wild-type transthyretin amyloid cardiomyopathy (wtATTR-CM) whose diagnosis was initially mistaken for isolated cardiac sarcoidosis after 18F-FDG/13N-ammonia PET/CT showed matching perfusion defects with focal FDG uptake. Despite methotrexate treatment, he developed progressive heart failure with serial echocardiography showing increasing left ventricular wall thickness and worsening global longitudinal strain, highlighting atypical imaging that can mimic other cardiomyopathies. The report emphasizes that wtATTR-CM can present with sarcoid-like PET patterns and that clinicians should consider amyloidosis when imaging findings are discordant or evolve despite immunosuppression.

Elalfy A, Kholeif Z, Rashwan R et al. · JACC. Case reports · (2026) · View on PubMed ↗

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Congenital Heart Disease & Structural Anomalies (including shunts)

Left ventricular diverticulum: A case report and differential diagnosis in an asymptomatic woman.

This case report studied an asymptomatic 68-year-old woman with systemic hypertension in whom transthoracic echocardiography suggested an interventricular communication due to a septal discontinuity and hypertrophic moderator band. Cardiac MRI on a 1.5-T system clarified the differential diagnosis by demonstrating a left ventricular diverticulum, a rare congenital myocardial outpouching that contracts synchronously with the left ventricle. The clinical significance is improved diagnostic accuracy for distinguishing left ventricular diverticulum from other ventricular outpouchings with different prognoses.

Andrea D’Arma GM, Montatore M, Masino F et al. · Radiology case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Four-dimensional flow CMR-based hemodynamic assessment of ALCAPA: A case report.

This case report studied anomalous left coronary artery from the pulmonary artery (ALCAPA) in a patient using contrast-free four-dimensional flow cardiac magnetic resonance (4D flow CMR) to quantify hemodynamics and define coronary course/ostium. The key finding was that 4D flow CMR maximum intensity projection images demonstrated right coronary artery dilation and the anomalous left coronary origin from the pulmonary artery. Scientifically and clinically, it supports 4D flow CMR as a useful noninvasive tool for understanding ALCAPA physiology and guiding treatment planning.

Oka H, Nakau K, Shibagaki Y et al. · Radiology case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Atypical Atrial Flutter Unveiling Cor Triatriatum Sinister in a Stable Adult.

This JACC Case Reports report describes a 64-year-old stable adult with atypical atrial flutter in whom transesophageal echocardiography (TEE) and cardiac magnetic resonance imaging (CMR) identified cor triatriatum sinister (CTS) with a left atrial membrane. The key finding is that TEE excluded intracardiac thrombus and incidentally revealed CTS, which was confirmed as nonobstructive by CMR, enabling safe TEE-guided electrical cardioversion. The clinical significance is that CTS can present with atrial arrhythmias even in asymptomatic adults, and multimodality imaging can directly guide management and anticoagulation decisions.

Panjiyar B, Herrera AJ, Hermann J et al. · JACC. Case reports · (2026) · View on PubMed ↗

This ECG Does Not Fit: Rethinking Left Ventricular Hypertrophy.

This case report evaluated a 70-year-old man with atypical ECG findings for left ventricular hypertrophy in the context of comorbid hypertension, diabetes, chronic kidney disease, and prior PCI, to determine whether Anderson-Fabry disease (AFD) explained the LVH. The key finding was that cardiac magnetic resonance showed reduced native T1 values and genetic testing identified the GLA mutation p.N215S (late-onset AFD), confirming the diagnosis despite confounding cardiovascular comorbidities. The clinical significance is that CMR native T1 plus targeted GLA genetic testing can clarify the etiology of LVH when ECG patterns are misleading.

Perini Schweiger C, Allocca G, Gugelmo G et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Topsy-Turvy Heart: Multimodality Prenatal and Postnatal Imaging for Clinical Management.

This JACC Case Reports article presents a prenatally diagnosed case of “topsy-turvy heart” with an aortopulmonary window, using combined fetal echocardiography and fetal cardiac magnetic resonance to guide perinatal management. The key finding was that multimodality prenatal imaging identified complex intracardiac anatomy and raised suspicion for associated airway abnormalities, which aligned with severe postnatal respiratory failure requiring mechanical ventilation. The significance is that integrating fetal echo with fetal CMR can improve anticipatory planning for complex congenital heart disease with extracardiac complications.

Meyer D, Geiger J, Weber R et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗

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Cardiac Oncology & Cancer-Related Cardiotoxicity

Trends in heart failure-related mortality among breast cancer patients in the United States from 1999 to 2024.

This retrospective analysis used the US CDC WONDER database to examine trends in heart failure (HF)-related mortality among women with breast cancer aged ≥25 years from 1999 to 2024, stratified by race/ethnicity and geography. The study found time trends in HF-related mortality across the period, indicating evolving HF burden in this population. These findings are clinically important for risk stratification and for guiding prevention and cardio-oncology surveillance strategies in breast cancer survivors.

Jaiswal V, Kumar D, Kalra K et al. · American journal of preventive cardiology · (2026) · View on PubMed ↗ · Free PDF ↗

Quantitative native T1 mapping identifies papillary muscle and intracavitary cardiac lipomas: A multiparametric CMR case series.

This retrospective multicenter French-Italian registry study examined iron chelation management in 167 transfused infants and toddlers with Diamond-Blackfan anemia syndrome (DBAS), focusing on chelation initiation before age 3. The key finding was that 38% initiated chelation early (median 18 months), with common indications of serum ferritin ≥500 ng/mL and >10 transfusions, and that deferasirox was the most used chelator. This is significant because it provides early-life real-world evidence to guide chelation strategies in DBAS patients at high risk for early iron overload.

Montatore M, Rella M, Milo M et al. · Radiology case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Cardiovascular Complications in Hemoglobinopathies: Pathophysiology, Clinical Spectrum, and Management.

This review summarized cardiovascular complications in hemoglobinopathies, focusing on sickle cell disease and thalassemia syndromes and their cardiac and vascular manifestations. It highlighted that improved survival from transfusion optimization, iron chelation, and disease-modifying therapies has revealed a broad spectrum of cardiomyopathy, heart failure, pulmonary hypertension, arrhythmias, microvascular ischemia, and valvular dysfunction. Scientifically and clinically, it emphasizes the need for phenotype-aware surveillance and management strategies tailored to the evolving cardiovascular pathophysiology in these patients.

Bradach D, Salavarria KC, Diaz-Arribasplata S et al. · European journal of haematology · (2026) · View on PubMed ↗

Radiation-Induced Acute Cardiac Injury in Patients With Left-Sided Breast Cancer: A Cardiac Magnetic Resonance Study on the Dose-Response Relation.

This prospective cardiac magnetic resonance (CMR) study evaluated radiation-induced acute cardiac injury in 64 patients with postoperative left-sided breast cancer undergoing radiotherapy, using pre- and post-treatment CMR strain analysis and dose calculations to cardiac structures. The abstract indicates a dose-response assessment of acute injury after whole-breast radiotherapy (40.5 Gy/15 fractions) versus other left-sided breast RT dosing, with the key finding being that acute cardiac injury could be detected by CMR strain in relation to delivered cardiac dose. These results support CMR strain as a technique for early identification of radiation-related cardiotoxicity risk in left-sided breast cancer patients, potentially enabling earlier intervention before long-term cardiovascular outcomes develop.

Zheng L, Yang M, Luo C et al. · International journal of radiation oncology, biology, physics · (2026) · View on PubMed ↗ · Free PDF ↗

Evolving paradigms in lymph node surgery in endometrial cancer: insights from the multicenter E-PEC trial.

This multicenter retrospective E-PEC study evaluated temporal trends in lymph node surgery for newly diagnosed endometrial cancer in six German university hospitals from 2018–2022. The key finding was that lymph node staging approaches evolved over time across participating centers, reflecting changing surgical paradigms during the study period. Scientifically and clinically, it informs how practice patterns in endometrial cancer nodal assessment have shifted and may guide future standardization of surgical staging strategies.

Eser B, Papior D, Salmanton-García J et al. · Archives of gynecology and obstetrics · (2026) · View on PubMed ↗ · Free PDF ↗

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Cardio-Oncology & Immunotherapy Response Imaging (PET/CT)

Beyond target lesions: Prognostic value of longitudinal AI-derived whole-body [1⁸F]FDG PET/CT metrics in metastatic melanoma.

This study evaluated an AI-based semi-automated tool for longitudinal whole-body [18F]FDG PET/CT quantification of total metabolic tumor volume (TMTV) and total lesion glycolysis (TLG) in 43 patients with unresectable metastatic melanoma receiving immune checkpoint inhibitor (ICI) therapy. Longitudinal AI-derived metabolic metrics beyond baseline “target lesion” response showed prognostic value for outcomes and provided additional risk stratification alongside established PET metabolic response criteria. These findings support using AI-derived whole-body metabolic trajectories to better predict prognosis in metastatic melanoma treated with ICIs.

Sachpekidis C, Vagenas TP, Müller M et al. · European journal of nuclear medicine and molecular imaging · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗

Compatibility of different PET/CT criteria in evaluating treatment response and survival in non-small cell lung cancer patients treated with immunotherapy.

This retrospective analysis evaluated concordance and overall survival (OS) associations of four 18F-FDG PET/CT immunotherapy response criteria—PERCIST, PECRIT, PERCIMT, and imPERCIST5—in 35 metastatic non-small cell lung cancer (NSCLC) patients receiving second-line or later immunotherapy. The key finding is that different PET/CT criteria classify metabolic response differently and show varying degrees of association with OS, with the study specifically testing both prognostic performance and mutual agreement among criteria. This is significant for clinical trial interpretation and routine practice because it informs which PET/CT response metric best aligns with survival outcomes under immunotherapy.

Eroğlu İ, Aydos U, Ateş YÜ et al. · Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · (2026) · View on PubMed ↗

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Vascular Function & Arterial Stiffness (PWV/Distensibility)

Associations between cardiovascular risk factors and diseases with aortic pulse wave velocity and aortic distensibility: magnetic resonance imaging in the Hamburg city health study.

This population-based Hamburg City Health Study used 2D phase-contrast-flow cardiovascular magnetic resonance (CMR) to quantify aortic pulse wave velocity (PWV) and aortic distensibility (AD) in 2270 participants and examined associations with cardiovascular risk factors and cardiovascular diseases. The key finding is that CMR-derived PWV and AD provide measurable, risk- and disease-related differences across the cohort, supporting their use as imaging biomarkers for cardiovascular risk stratification. Scientifically, the study strengthens the evidence base for CMR vascular functional metrics as noninvasive markers that may improve identification of individuals at higher cardiovascular risk.

Riedl KA, Di Carluccio E, Huellebrand M et al. · Clinical research in cardiology : official journal of the German Cardiac Society · (2026) · View on PubMed ↗ · Free PDF ↗

Integrating Multimodal Data and Genomics for a Comprehensive Assessment of Cardiovascular Aging and Its Impact.

This study used UK Biobank participants to quantify cardiovascular aging by integrating multimodal biomarkers from cardiovascular magnetic resonance (CMR), electrocardiography, arterial stiffness, and carotid ultrasound, and then assessed the genetic architecture, lifestyle determinants, and prognostic relevance of the resulting cardiovascular age measure using machine-learning models. The key finding was that an ML-derived cardiovascular aging score based on these multimodal imaging/vascular biomarkers captures meaningful variation in cardiovascular aging and links it to genetic and lifestyle determinants with prognostic value. This supports a more comprehensive, genomics-informed approach to risk stratification for cardiovascular disease using routinely obtainable multimodal cardiovascular phenotypes.

Abula A, Yuan Y, Li X et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗

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Systemic/Autoimmune/Drug-Triggered Cardiac Events

Metabolic and redox pathway dysregulation in HIV-associated coronary endothelial dysfunction.

This prospective observational study combined stress cardiovascular magnetic resonance imaging with high-throughput serum proteomics in 45 virally suppressed people with HIV (PWH) and 29 matched controls to investigate coronary endothelial dysfunction mechanisms. The key finding was that endothelial dysfunction in treated HIV is associated with circulating proteomic signatures indicating metabolic and redox pathway dysregulation. Mechanistic biomarker identification could support earlier detection and more targeted therapeutic approaches to reduce cardiovascular risk in virally suppressed PWH.

Keole KS, Bukhari S, Minhas AS et al. · American journal of physiology. Heart and circulatory physiology · (2026) · View on PubMed ↗

Cardiogenic shock after ocrelizumab infusion in relapsing-remitting multiple sclerosis.

This report documents a 42-year-old man with relapsing-remitting multiple sclerosis who developed cardiogenic shock with reversible severe left ventricular systolic dysfunction after ocrelizumab infusion. The key finding is that comprehensive evaluation—including coronary angiography, cardiac magnetic resonance imaging, and endomyocardial biopsy—excluded ischemic and infectious causes, supporting ocrelizumab as a rare trigger for reversible cardiac dysfunction. Clinically, it underscores the need for vigilance and prompt cardiac assessment in patients receiving ocrelizumab who develop symptoms of heart failure or shock.

De Napoli G, Gotti E, Baldovini C et al. · Multiple sclerosis (Houndmills, Basingstoke, England) · (2026) · View on PubMed ↗

Deramiocel heart-derived cellular therapy in advanced Duchenne muscular dystrophy (HOPE-3): a phase 3, randomised, double-blind, placebo-controlled trial.

This phase 3, randomized, double-blind, placebo-controlled trial (HOPE-3) studied deramiocel, a heart-derived cellular therapy of human allogeneic cardiosphere-derived cells, in participants aged ≥10 years with advanced Duchenne muscular dystrophy (DMD). The key finding was that deramiocel improved clinical outcomes compared with placebo while maintaining an acceptable safety profile in advanced DMD, extending earlier phase 1–2 signals and supporting HOPE-2 findings. Clinically, it provides evidence for a potential disease-modifying adjunct therapy targeting both cardiac and skeletal muscle dysfunction in DMD.

McDonald CM, Villa C, Soslow JH et al. · Lancet (London, England) · (2026) · View on PubMed ↗ · Free PDF ↗

Inaugural complete heart block in anti-SSA negative systemic lupus erythematosus: the diagnostic role of anti-PM-Scl 100 antibodies.

This case report studied inaugural complete heart block (CHB) in a 21-year-old woman with anti-SSA–negative systemic lupus erythematosus (SLE), using cardiac MRI and immunologic testing including anti–PM-Scl 100 antibodies. The key finding was that CHB occurred despite anti-SSA negativity, and anti–PM-Scl 100 positivity (with exclusion of myocarditis/infiltrative and reversible causes) supported an SLE-related diagnosis. Clinically, it highlights anti–PM-Scl 100 antibodies as a diagnostic clue for rare adult SLE-associated CHB when anti-SSA/Ro is absent.

Dammene Debbih N, Laouar L, Dekdouk N et al. · Lupus · (2026) · View on PubMed ↗ · Free PDF ↗

Imaging Modalities Related to Cardiac Involvement in Systemic Sclerosis.

This review studied the evidence base for imaging modalities used to assess cardiac involvement in systemic sclerosis (SSc), a disease driven by microvasculopathy, autoimmunity, and fibrosis. The key finding was a synthesis of how different imaging techniques (e.g., echocardiography, cardiac MRI, and other modalities) contribute to identifying SSc-related cardiac inflammation and fibrosis as well as pulmonary vascular complications that affect the heart. Clinically, it provides a framework for selecting and interpreting cardiac imaging in SSc to improve early detection and monitoring of prognostically important cardiac phenotypes.

Markousis-Mavrogenis G, Sfikakis PP, Matucci-Cerinic M et al. · Journal of the American Heart Association · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗

Cardiac Imaging Phenotypes in Systemic Inflammatory Disorders and Perspectives: What Have We Learned and Where Do We Need to Go Next?

This review studied cardiac imaging phenotypes across systemic inflammatory autoimmune rheumatic diseases (SARDs) and assessed what is known and what remains to be developed. The key finding was that cardiovascular involvement is often subclinical and heterogeneous, and that imaging phenotyping is central to early detection, characterization, and longitudinal monitoring. This is significant for guiding future research toward more pathophysiology-driven imaging biomarkers and improved diagnostic strategies in SARDs.

Buch MH, Plein S · Journal of the American Heart Association · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗

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Infectious Disease & Global Health Cardiovascular Impacts

Lymphatic endothelial cells actively shape immune responses in the lungs.

This review studied how lymphatic endothelial cells (LECs) in the lungs actively regulate immune responses, focusing on organ-specific LEC differentiation and mechanisms such as PAR1-mediated lymphatic junction permeabilization. It reports experimental evidence that pulmonary LECs limit acute inflammation, modulate adaptive immunity, and influence tissue remodeling through active signaling and barrier/junction control. These findings highlight pulmonary LECs as potential therapeutic targets to tune inflammation and immunity in lung disease.

Rivers AK, Migues Ramirez C, Cleary SJ · Current opinion in immunology · (2026) · View on PubMed ↗ · Free PDF ↗

The intersection of infectious diseases and cardiovascular disease in Africa: A narrative review.

This narrative review studied the intersection of infectious diseases and cardiovascular disease in sub-Saharan Africa, emphasizing how infections and reactivation in immunosuppressed people (including those with HIV/AIDS) affect cardiac targets. It concludes that environmental and healthcare factors (poor sanitation, overcrowding, inadequate housing) facilitate infection spread and thereby worsen cardiovascular complications, including those driven by neglected tropical diseases and latent parasitic infections. The review is clinically significant because it frames cardiovascular risk in Africa as inseparable from infectious disease control and prevention strategies.

Ogah OS, Umuerri EM, Hahnle J et al. · Journal of the National Medical Association · (2026) · View on PubMed ↗

Imaging insights into systemic tuberculosis with cardiac involvement: A rare challenging case of tuberculous chronic constrictive pericarditis and myocarditis.

This report describes a rare case of systemic tuberculosis with cardiac involvement presenting as chronic constrictive pericarditis and myocarditis, emphasizing the diagnostic role of multimodal imaging when microbiological confirmation is lacking. The key finding is that advanced imaging can reveal patterns consistent with tuberculous cardiac disease across pericardial and myocardial involvement despite diagnostic uncertainty. Clinically, it highlights multimodal imaging as a critical tool for improving diagnostic accuracy in challenging cardiac TB presentations.

Jabri M, Boulouiz S, Bazid Z et al. · Radiology case reports · (2026) · View on PubMed ↗ · Free PDF ↗

Mortality among people who had contact with the criminal justice system during adolescence: a systematic review and meta-analysis.

This systematic review and meta-analysis synthesized cohort evidence on mortality after adolescent contact with the criminal justice system, including deaths from all-cause and specific causes (e.g., suicide, homicide, injuries, and substance-related causes) in people exposed before age 20. The key finding was that criminal justice contact in adolescence is associated with increased mortality risk compared with the general population, with variation by cause and risk factors. This is significant for public health and policy because it quantifies an elevated long-term risk that can inform targeted prevention and follow-up interventions.

Martinez A, Janca E, Willoughby M et al. · Social science & medicine (1982) · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗

Safety and efficacy of intravenous thrombolytics among patients with emergent intracranial stenting after thrombectomy: Subanalysis of the RESISTANT registry.

This subanalysis of the RESISTANT registry evaluated safety and efficacy of intravenous thrombolysis (IVT) before endovascular therapy (EVT) with emergent intracranial stenting in acute ischemic stroke patients with intracranial atherosclerotic disease (ICAD)-large vessel occlusion (LVO). The key finding is that IVT in this setting can be assessed for functional outcome (ordinal modified Rankin Scale at 90 days) and secondary endpoints such as excellent outcome (mRS 0–1), addressing whether IVT adds benefit or increases risk when adjuvant stenting is used. The clinical significance is that it informs treatment sequencing decisions for patients undergoing EVT plus emergent stenting in ICAD-LVO.

Mujanovic A, Olivé-Gadea M, Diana F et al. · International journal of stroke : official journal of the International Stroke Society · (2026) · View on PubMed ↗ · Free PDF ↗

Procedural and Therapy Peripheral Intravenous Catheters: A Framework for Safety, Quality and Patient-Centred Care.

This narrative review introduced a conceptual framework for peripheral intravenous catheters that differentiates devices by dwell time and therapeutic purpose to improve safety, quality, and cost-effectiveness. The key finding is the framework’s rationale—supported by guideline- and evidence-based synthesis—that tailoring catheter selection to intended use duration and therapy reduces complications and improves appropriateness. Scientifically, it provides a structured approach for clinicians and researchers to standardize catheter decision-making and evaluate outcomes by catheter type and context.

Drugeon B, Rickard CM, Peters N et al. · Journal of advanced nursing · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗

Strategies for resilient climate in smart cities mediated by Nash equilibrium and autonomous decision-makers.

This study examined a decision-making framework for climate resilience in smart cities, modeling each city as an autonomous agent using Nash equilibrium combined with autonomous multi-agent systems and machine learning. The key finding is that the integrated approach can generate city-specific policies for pollution levels and climate-warming risk management under global warming pressures. Scientifically, it provides a computational strategy for tailoring greenhouse-gas mitigation and adaptation actions to heterogeneous urban conditions rather than using one-size-fits-all plans.

Latha CM, Alvarado-Mentado M · Journal of environmental management · (2026) · View on PubMed ↗

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Generated automatically on August 01, 2026. Covers PubMed articles published July 25, 2026 – August 01, 2026. Summaries are AI-generated; always consult the original publication for clinical or research decisions.