What's New in Cardiac MRI? — October 16, 2026
AI-summarised digest of 65 PubMed articles on Cardiac MRI published in the last 7 days.
Jump to category
What’s New in Cardiac MRI?
October 16, 2026 · 65 articles · 35 research themes · covering October 09, 2026 – October 16, 2026
Overview
This week’s digest is dominated by a clear push toward precision cardiovascular phenotyping using advanced imaging and biomarker integration—especially cardiac MRI. Multiple papers emphasize that “conventional” metrics (standard risk scores, single-parameter imaging, or presence/absence of LGE) are often insufficient for modern, heterogeneous patient groups such as cancer patients, congenital heart disease populations, and HFpEF. Instead, studies highlight incremental value from combining modalities (e.g., biomarkers plus imaging), extracting richer tissue and functional information (strain, T1/T2 mapping, myocardial work, perfusion, feature tracking), and using more interpretable or standardized approaches so results can be compared across time and sites.
A second major theme is improving clinical decision-making by refining thresholds, harmonizing protocols, and validating new metrics. Reviews and statements on CMR strain standardization, plus studies on LGE quantification cutoffs, T1 mapping ROI choices, and 4D flow acquisition variability, collectively point to a field that is moving from “can we measure it?” toward “can we measure it reliably and meaningfully?” This is complemented by prognostic modeling work (e.g., ECV-informed prediction after STEMI) and by efforts to distinguish normal physiologic evolution from pathology (e.g., post-transplant T1/T2 trajectories).
Finally, several articles underscore the clinical importance of recognizing specific high-risk phenotypes—ranging from chemotherapy- and infection-associated myocardial injury that can mimic ACS, to eosinophilic and immune-mediated myocarditis with thrombotic complications, to inherited arrhythmia substrates and malignant mitral valve prolapse. Together, they reinforce a practical message: when symptoms and ECG/biomarkers are ambiguous, multimodality imaging and careful phenotyping can prevent misdiagnosis, guide therapy, and identify patients at risk of sudden deterioration.
Cardio-oncology biomarkers & risk stratification
Fully quantitative CMR rest perfusion reveals myocardial perfusion abnormality in Kawasaki disease: Association with left ventricular Remodeling.
This prospective single-center study assessed children with Kawasaki disease (n=87; mean age 7.5 years) using fully quantitative cardiac MRI rest perfusion to measure myocardial blood flow (MBF) corrected for heart rate–blood pressure product (MBFcor). Kawasaki disease patients demonstrated myocardial perfusion abnormalities on rest perfusion imaging, which were associated with left ventricular remodeling. These results support quantitative CMR perfusion as a marker of myocardial injury burden and a potential tool for tracking remodeling risk in pediatric Kawasaki disease.
Zhou Z, Ye P, Wang C et al. · International journal of cardiology · (2026) · View on PubMed ↗
Impact of the Extent, Pattern, and Location of Replacement Myocardial Fibrosis on Clinical Outcomes in Aortic Regurgitation.
This retrospective cohort study assessed how the extent, pattern, and anatomical location of late gadolinium enhancement (LGE) replacement myocardial fibrosis on contrast-enhanced CMR relates to clinical outcomes in patients with chronic aortic regurgitation (AR). The key finding was that specific LGE characteristics (beyond presence alone) were associated with major adverse cardiovascular events (MACE), including cardiovascular death, heart transplantation, and heart-failure rehospitalization. Clinically, it supports using detailed LGE phenotyping to refine prognosis and potentially guide risk-adapted management in chronic AR.
Li B, Dai L, Liu Y et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗
Toward Precision Cardio-Oncology: Integrating Biomarkers and Cardiac Imaging for Cardiovascular Risk Assessment in Patients With Cancer.
This narrative review examined how to integrate circulating biomarkers (including high-sensitivity cardiac troponins and natriuretic peptides) with multimodality cardiac imaging (e.g., echocardiography) to refine cardiovascular risk stratification in patients with cancer across treatment phases. It found that conventional cardiovascular risk scores are inadequate for oncology populations and that combining myocardial injury and hemodynamic-stress biomarkers with imaging can better capture treatment-related cardiovascular risk before, during, and after therapy. This supports a precision cardio-oncology approach to identify patients at higher risk of cardiotoxicity and improve clinical decision-making for cancer treatment delivery and long-term outcomes.
Sabouret A, Giamundo DM, Mamas M et al. · Oncology research and treatment · (2026) · View on PubMed ↗
Pediatric vascular health & arterial stiffness norms
Age-specific reference values for pulse wave velocity in paediatric populations: a systematic review with meta-analysis.
This systematic review and meta-analysis studied age-specific pulse wave velocity (PWV) reference values in healthy paediatric populations using observational studies stratified by age (and additional sex stratification where available). It reported pooled PWV estimates with age-specific reference ranges derived from random-effects models, addressing the lack of well-defined paediatric PWV norms. These reference values can improve interpretation of arterial stiffness measurements in children and enable more accurate early identification of vascular risk.
Martínez-Cifuentes Ó, Nilsson PM, Saz-Lara A et al. · Journal of hypertension · (2026) · View on PubMed ↗
Genetic cardiomyopathies & inherited arrhythmia risk
The Innocent Delta Wave in Progressive Cardiomyopathy - Culprit vs Bystander.
This case report described a 34-year-old man with progressive cardiomyopathy and recurrent arrhythmias who developed an acute ischemic stroke, with echocardiography showing a hypertrophic cardiomyopathy (HCM) phenotype and moderate left ventricular systolic dysfunction. The clinical course highlighted an “innocent delta wave” on ECG as a bystander rather than the primary driver of events, in the context of atrial fibrillation and underlying HCM with conduction disease in the family. The report emphasizes careful interpretation of ECG findings in HCM patients and the importance of evaluating for arrhythmia and structural disease when stroke occurs.
Ansari AG, Shanmugam S, Vijay J et al. · The American journal of cardiology · (2026) · View on PubMed ↗
LGL-Phenocopy With Dual AV Nodal Physiology and Malignant SVT: A Diagnostic Pitfall With Sudden Deaths.
This case report studied a 45-year-old man with Lown-Ganong-Levine (short PR without preexcitation) phenocopy and malignant supraventricular tachycardia, using serial ECGs and postconversion rhythm assessment to characterize atrioventricular nodal physiology. The patient demonstrated dual AV nodal physiology with SVT (~220 bpm) and a family history of sudden cardiac death in three siblings, indicating that the “benign” LGL-phenocopy pattern can reflect malignant arrhythmogenic substrates. Clinically, it highlights the need for careful electrophysiologic evaluation and risk consideration when short PR/LGL-phenocopy coexists with malignant SVT and strong familial SCD.
Negm AY, Zhfan S, Khalil M et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Compound MYH7 Mutations: Risk Stratification Challenges in an Affected Family.
This case report studied a familial hypertrophic cardiomyopathy (HCM) pedigree undergoing sudden cardiac death risk stratification, focusing on compound MYH7 mutations (Ala655Thr and Gly571Arg) and borderline phenotype expression. The proband carried only Ala655Thr with mild septal hypertrophy and nonsustained ventricular tachycardia, while his daughter had obstructive HCM, cardiac arrest, and an implantable cardioverter-defibrillator after septal myomectomy. The findings emphasize that MYH7 genotype–phenotype relationships and SCD risk prediction can be difficult in genotype-positive relatives with subtle or variable expression.
Hammad A, Yeung A, Goldschmidt H et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Recurrent Nonischemic Left Ventricular Aneurysms: A Cardiac MRI-Driven Diagnosis in a DES Variant Carrier.
This case report studied a 24-year-old man with recurrent nonischemic left ventricular aneurysms in the setting of a disease-causing (DES) variant carrier, using cardiac magnetic resonance (CMR) for tissue characterization and localization. Initial CMR showed an apical true aneurysm treated surgically, and five years later CMR identified a new inferolateral basal aneurysm in a previously normal region after re-evaluation for recurrent ventricular tachycardia. The clinical significance is that CMR can drive diagnosis and surveillance for evolving aneurysm formation in genetic cardiomyopathy, potentially guiding timely intervention.
Garcia NP, Forti D, Tassine Penatti LA et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Ventricular Fibrillation in PRKAG2 Cardiomyopathy: A Genetic Arrhythmia Substrate Beyond Wolff-Parkinson-White.
This JACC Case Reports article described a 25-year-old woman with genetically confirmed PRKAG2 cardiomyopathy who presented with out-of-hospital cardiac arrest, using echocardiography, cardiac magnetic resonance imaging, and electrophysiological study to characterize the arrhythmia substrate. The key finding was ventricular fibrillation occurring in the setting of PRKAG2 syndrome, with electrophysiological testing excluding Wolff-Parkinson-White syndrome as the cause of pre-excitation. Clinically, it highlights PRKAG2-related conduction system disease as a substrate for malignant ventricular arrhythmias beyond classic WPW physiology.
Visch J, Hopman LHGA, Holtus D et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac MRI strain & standardized imaging protocols
Comparison of Septal Region-of-Interest and Whole-Myocardium Contouring Methods for Myocardial T1 Measurement in Metabolic Syndrome.
This JoVE protocol study compared septal region-of-interest (ROI) versus whole-myocardium contouring methods for myocardial T1 mapping in metabolic syndrome (MetS), particularly addressing whether to exclude focal LGE scar regions. The key finding was that T1 values derived from a septal ROI approach (avoiding LGE lesions) can differ from conventional whole-myocardium measurements and may affect predictive performance for MetS-related myocardial remodeling. Methodologically, it provides a practical framework for standardizing T1 quantification strategies in the presence of focal LGE.
Zhao Y, Yang H, Zhang M et al. · Journal of visualized experiments : JoVE · (2026) · View on PubMed ↗
Cardiovascular magnetic resonance derived myocardial strain: applications, acquisition techniques, analysis, and reporting. A Scientific Statement of the Society for Cardiovascular Magnetic Resonance, Radiological Society of North America, and the European Association of Cardiovascular Imaging of the ESC.
This scientific statement reviewed and standardized cardiovascular magnetic resonance (CMR) myocardial strain imaging, covering applications, acquisition techniques, analysis, and reporting. The key finding was that CMR-derived strain provides incremental diagnostic and prognostic value but clinical adoption is limited by variability in protocols, noise sensitivity, and insufficient robust normative reference ranges across age, sex, and ethnicity. The statement’s significance is that it provides consensus guidance to harmonize strain measurement and reporting to enable broader routine clinical use.
Gulsin GS, Ambale-Venkatesh B, Axel L et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiovascular magnetic resonance derived myocardial strain: applications, acquisition techniques, analysis, and reporting.
This European Heart Journal–Cardiovascular Imaging review studied cardiovascular magnetic resonance (CMR)–derived myocardial strain, focusing on applications, acquisition techniques, analysis methods, and reporting standards. It found that CMR strain imaging provides incremental diagnostic and prognostic value over conventional imaging parameters across multiple cardiac diseases, but that clinical adoption is limited by lack of standardized protocols, noise sensitivity, and insufficient normative reference ranges by age, sex, and ethnicity. Scientifically, it supports harmonization of CMR strain acquisition/analysis and development of robust reference standards to enable reliable routine clinical use.
Gulsin GS, Ambale-Venkatesh B, Axel L et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗ · Free PDF ↗
Viral latency & post-MI immune inflammation
Cytomegalovirus Latency Fuels Inflammation Following Myocardial Infarction.
This Circulation Research study investigated how latent murine cytomegalovirus (CMV) infection affects cardiac immune cell dynamics and post–myocardial infarction (MI) inflammation in C57BL/6J mice. The key finding was that latent CMV alters inflammatory responses during MI repair, characterized using spectral flow cytometry and bulk and single-cell RNA/T-cell receptor (TCR) sequencing. This mechanistic evidence links CMV latency to adverse post-MI remodeling processes and supports targeting virus-driven inflammation as a potential therapeutic strategy.
Dapergola E, Šustić M, Ashour D et al. · Circulation research · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗
Fetal cardiac imaging & congenital outflow tract anomalies
Prenatal Diagnosis of Distal Aortopulmonary Window by Fetal Cardiac MRI.
This case report studied prenatal detection of a distal aortopulmonary window in a single fetus referred for fetal cardiac MRI after suboptimal great-vessel visualization on ultrasound. Fetal cardiac MRI demonstrated a distal aortopulmonary window with a characteristic “heart-shaped” great-vessel appearance. The finding supports fetal cardiac MRI as a complementary technique to echocardiography for characterizing complex fetal outflow tract abnormalities when ultrasound is limited.
Verley M, Anquetil S, Ferreira LN et al. · JACC. Case reports · (2026) · View on PubMed ↗
Hormonal therapies in heart failure (testosterone/cortisol modulation)
Effects of testosterone on exercise capacity in postmenopausal women with stage B heart failure.
This randomized, double-blind, placebo-controlled crossover trial studied whether transdermal testosterone (5 mg/day) improves exercise capacity in postmenopausal women (age ≥55) with stage B heart failure and reduced V˙O2peak. The abstract truncates before reporting the trial’s primary results. If effective, testosterone could represent a targeted hormonal intervention to improve functional capacity in women with early-stage (stage B) heart failure.
Grant J, Alexander SE, Marwick TH et al. · Climacteric : the journal of the International Menopause Society · (2026) · View on PubMed ↗
Cardiovascular effects of metyrapone treatment in patients with mild autonomous cortisol secretion: a secondary analysis.
This secondary analysis studied cardiovascular effects of cortisol-lowering therapy with metyrapone in 15 patients with mild autonomous cortisol secretion (MACS) before and after 12 weeks of evening dosing (500 mg at 6 PM and 250 mg at 10 PM). The abstract truncates before providing the key outcomes on blood pressure regulation, cardiac fat depots, and myocardial function/morphology. Clinically, demonstrating cardiovascular benefit would strengthen the rationale for treating MACS to reduce downstream cardiovascular risk.
Niziolek H, Just I, Baumgartner C et al. · The Journal of clinical endocrinology and metabolism · (2026) · 2 citations · View on PubMed ↗ · Free PDF ↗
Echocardiography–CMR concordance for valvular disease severity
Optimizing Echocardiographic Evaluation of Chronic Mitral Regurgitation: Comparison With Cardiac Magnetic Resonance Imaging and Implications for Guideline Recommendations.
This prospective study evaluated how to optimize American Society of Echocardiography (ASE) criteria for diagnosing definite severe chronic mitral regurgitation by comparing transthoracic echocardiography against quantitative cardiac magnetic resonance (CMR) in 177 patients. The abstract truncates before stating the performance results of the ASE criteria when fewer than four criteria are present. The work is significant because it could refine guideline-based echocardiographic thresholds to better match CMR severity and improve MR classification in practice.
El-Tallawi KC, Angulo C, Chamsi-Pasha M et al. · JACC. Cardiovascular imaging · (2026) · View on PubMed ↗
Cardiac MRI in pediatric transplant monitoring
Diffuse elevations of T1 and T2 are common in newly transplanted pediatric cardiac grafts without rejection and decrease over time.
This prospective CMR study examined temporal patterns of diffuse T1 and T2 elevations in 14 pediatric heart transplant recipients without acute rejection, using non-contrast 1.5T CMR (22 scans) alongside routine catheterization. The abstract truncates before detailing the magnitude of change, but the title indicates that T1/T2 elevations are common in newly transplanted grafts (≤6 months) and decrease over time. Scientifically, these findings help distinguish normal post-transplant CMR evolution from rejection-related myocardial injury signals.
Vegulla RV, Blackwell S, Ceneri NM et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗
Cardiac microvascular dysfunction (CMD) in structural heart disease & HFpEF
Coronary microvascular dysfunction in patients undergoing transcatheter aortic valve implantation: A systematic review and meta-analysis.
This systematic review and meta-analysis studied coronary microvascular dysfunction (CMD) in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI), focusing on pooled CMD prevalence, post-TAVI changes in coronary flow reserve (CFR) and microvascular resistance, and prognostic impact on major adverse cardiovascular events (MACE). The abstract truncates before providing the pooled prevalence, trajectory estimates, or effect sizes. The clinical significance is that defining CMD frequency and prognostic value could improve risk stratification and guide post-TAVI monitoring or therapies.
Panyawongkhanti M, Chintrakulchai P, Tanking C et al. · PloS one · (2026) · View on PubMed ↗
Left ventricular end-diastolic pressure in women with ischemia and no obstructive coronary artery disease: The women’s ischemia syndrome evaluation - Coronary microvascular dysfunction study (WISE-CVD).
This study enrolled 253 women with ischemia and no obstructive coronary artery disease (INOCA) to test whether coronary microvascular dysfunction (CMD) affects left ventricular end-diastolic pressure (LVEDP), using invasive coronary functional testing (CFT) and a predefined subset undergoing cardiac MRI. CMD-mediated impairment in LV relaxation was associated with elevated LVEDP, supporting a mechanistic pathway from microvascular dysfunction to HFpEF physiology. Clinically, measuring LVEDP and LV relaxation in INOCA/CMD may improve understanding and targeting of HFpEF risk in women.
Ranasinghe S, Tjoe B, Chang J et al. · International journal of cardiology · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗
Pattern and texton-based feature descriptors for diabetic foot ulcer detection.
This paper studied a deep learning strategy for diabetic foot ulcer (DFU) detection, proposing the DLS-DFUD framework that uses wavelet transform-based Wiener filtering (WT-WF) for preprocessing, followed by segmentation, feature extraction using pattern/texton-based descriptors, and classification. The key finding is that the proposed pipeline provides a structured approach to improve DFU image quality and extract discriminative features for more accurate ulcer detection. This is significant because earlier and more precise DFU detection can reduce downstream infections and amputations in people with diabetes.
Mastanvali, Rajini NH, Laxmaiah M · Expert review of medical devices · (2026) · View on PubMed ↗
Regional fat distribution as a determinant of mortality in populations with left ventricular systolic dysfunction: challenging the obesity paradox.
This study examined whether regional fat distribution predicts mortality in individuals with left ventricular systolic dysfunction, addressing the “obesity paradox,” using UK Biobank Imaging Enhancement Programme participants who underwent cardiac magnetic resonance (CMR). The key finding was that CMR-defined left ventricular systolic impairment (LVEF <50%) combined with specific adiposity phenotypes based on regional fat distribution provided prognostic information beyond body mass index (BMI). This is clinically significant because it suggests that fat distribution—not just BMI—may better stratify risk in patients with LV systolic dysfunction.
Khanna S, Ho W, Takeuchi F et al. · European journal of preventive cardiology · (2026) · 9 citations · View on PubMed ↗
Cardiac MRI reconstruction & computational imaging methods
Latent Interpolation Learning Using Diffusion Models for Cardiac Volume Reconstruction.
This engineering study proposed a diffusion-model-based method, Cardiac Latent Interpolation Diffusion (CaLID), for cardiac volume reconstruction from sparsely acquired 2D short-axis CMR slices. The abstract truncates before reporting quantitative reconstruction performance or comparisons to baseline interpolation methods. If successful, CaLID could improve 3D cardiac assessment without requiring predefined interpolation schemes or additional semantic inputs like segmentation labels or motion data.
Bubeck N, Shit S, Chen C et al. · IEEE transactions on medical imaging · (2026) · View on PubMed ↗
BHSMS: a new software for searching the most stable structure of clusters based on the improved basin hopping algorithm.
The study developed BHSMS, a new global-minimum search software package for atomic and molecular clusters, implementing an improved basin-hopping (BH) algorithm combined with structure relaxation (SR), structure similarity recognition (SSR), planarity recognition (PR), and constraints for molecular rotation (CMR). The key finding is that BHSMS provides an efficient workflow to search for the most stable (global-minimum) cluster structures by integrating these recognition/constraint algorithms with improved BH. This is significant for cluster science because it can accelerate and improve the identification of ground-state geometries that underpin predicted cluster properties in quantum-chemistry workflows.
Zhang YY, Cheng Y, Zhang SW et al. · Physical chemistry chemical physics : PCCP · (2026) · View on PubMed ↗
Oncology treatment cardiotoxicity & chemotherapy-associated arrhythmias
FOLFOX-Associated Ventricular Fibrillation Arrest in a Patient With Colon Cancer.
This JACC Case Reports article described a 43-year-old man with stage IIIB colon cancer who developed ventricular fibrillation arrest about 72 hours after the first FOLFOX cycle (leucovorin, fluorouracil [5-FU], and oxaliplatin). The key finding was fluoropyrimidine-associated cardiotoxicity presenting with ST-segment elevations and severe left ventricular dysfunction that improved on cardiac MRI without myocardial edema or late enhancement. The clinical significance is heightened awareness of life-threatening arrhythmias with FOLFOX and the potential role of cardiac MRI in characterizing myocardial injury patterns.
Al Osta S, Ahmed M, Xu WD et al. · JACC. Case reports · (2026) · View on PubMed ↗
AI/deep learning for cardiovascular imaging & diagnostics
AI and Deep Learning in Cardiovascular Imaging: From Risk Stratification to Precision Phenotyping.
This review article studied how artificial intelligence (AI) and deep learning can be applied to cardiovascular imaging across tasks such as risk stratification and precision phenotyping. The abstract truncates before listing specific model results, but it emphasizes summarizing AI/deep-learning fundamentals and current applications across imaging modalities. The significance is that it provides a framework for translating AI methods into clinical cardiovascular imaging workflows and improving quantitative, prognostic phenotyping.
Diao K, Lu J, Dimitrakakis A et al. · Arteriosclerosis, thrombosis, and vascular biology · (2026) · View on PubMed ↗
Cardiac MRI biomarkers for systemic/brain vascular disease link
Left ventricular myocardial strain impairment correlates with cerebral small vessel disease burden in patients with normal ejection fraction.
This cross-sectional study evaluated whether subclinical left ventricular myocardial dysfunction, assessed by cardiac MRI in 139 participants with preserved left ventricular ejection fraction, correlates with cerebral small vessel disease (CSVD) burden measured on brain MRI. Left ventricular myocardial strain impairment was associated with higher CSVD burden. These findings support a heart–brain microvascular link and suggest that subtle LV dysfunction may help identify patients at greater risk of CSVD-related brain injury even when ejection fraction is normal.
Wang W, Zhang X, Liang M et al. · Brain research bulletin · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac amyloidosis & noninvasive burden estimation
Septal thickness to QRS voltage ratio in Lead I/aVR: A simple tool for estimating cardiac amyloid burden.
This diagnostic study evaluated whether an echocardiographic-electrocardiographic index—maximum septal thickness (MST) divided by QRS voltage in lead I and/or aVR—can estimate cardiac amyloid burden in patients with suspected cardiac amyloidosis. The MST/QRS voltage ratio correlated with cardiac MRI-derived extracellular volume (ECV), offering a simpler alternative when ECV measurement is limited. If validated broadly, this tool could enable more accessible noninvasive screening and risk stratification for cardiac amyloidosis.
Sclafani M, Arcari L, Tini G et al. · International journal of cardiology · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗
CMR T1/T2 mapping & diffuse myocardial injury/fibrosis
Rotating Frame Spin-Lock Cardiac MRI Method at 9.4 T Can Characterize Diffuse Fibrosis in Progressing Hypertensive Heart Disease in Mice.
This preclinical mouse study used a rotating frame spin-lock cardiac MRI approach at 9.4 T—continuous wave T1ρ and RAFF2 (relaxation along a fictitious field with Rank 2)—to characterize diffuse myocardial fibrosis in angiotensin II–induced hypertensive heart disease (HHD) with diastolic dysfunction, and compared it with native T1 and late gadolinium enhancement (LGE). The key finding was that CW-T1ρ and RAFF2 provided fibrosis-related contrast that complements or improves characterization of diffuse fibrosis progression relative to conventional native T1 and LGE in progressing HHD. Scientifically, it advances quantitative, noninvasive MRI methods for detecting diffuse fibrotic remodeling earlier than LGE alone, with potential translational value for monitoring hypertensive cardiomyopathy.
Kiviluoto R, Törmä D, Tawfek A et al. · Magnetic resonance in medicine · (2026) · View on PubMed ↗ · Free PDF ↗
CMR hemodynamics & 4D flow standardization
4D Flow Acquisition Parameters as Technical Correlates of Hemodynamic Measurements: An Analysis of the multicenter Tetralogy of Fallot Registry of 4D flow Energetics and Kinetics (TREK).
This multicenter observational study evaluated how 4D flow CMR acquisition parameters (including magnet vendor, sequence choice, and signal quality) affect derived hemodynamic biomarkers—kinetic energy (KE), vorticity (ω), and viscous energy loss (VEL)—in repaired tetralogy of Fallot (rTOF) patients enrolled in the TREK registry. The key finding was that real-world variability in 4D flow acquisition technical factors meaningfully correlates with differences in aortic and right-ventricular 4D flow measurements, indicating that biomarker sensitivity is not purely biological. Clinically, this supports harmonization/standardization (or parameter-aware interpretation) of 4D flow acquisition when using energetics and kinetics biomarkers for rTOF risk stratification and longitudinal comparisons across sites.
Loke YH, Lee M, O’Hara R et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
Establishing the reliability of non-contrast 4D flow in congenital heart disease at 1.5T.
This prospective cohort study evaluated the reliability of non-contrast 4D flow cardiac MRI at 1.5T in pediatric and young adult patients with congenital heart disease by comparing non-contrast 4D flow (NC 4D Flow) to 2D phase-contrast (2D PC) flow and ventricular stroke volumes. The key finding was that NC 4D Flow correlated well with 2D PC measurements and stroke volumes, with agreement assessed using correlation statistics and Bland–Altman comparisons. Clinically, establishing NC 4D flow reliability supports broader use of 4D flow without contrast exposure in congenital heart disease imaging workflows.
Brown NK, Romberg EK, Schmitt C et al. · Pediatric radiology · (2026) · View on PubMed ↗ · Free PDF ↗
Myocardial work (PV-loop) & subtype phenotyping
Myocardial work in light-chain and transthyretin-related amyloidosis with preserved ejection fraction: a cardiovascular magnetic resonance study.
This prospective CMR study evaluated myocardial work derived from pressure–volume loop (PV-loop) analysis in 100 confirmed cardiac amyloidosis patients with preserved LVEF (86 AL-CA and 14 ATTR-CA) versus 40 matched healthy controls. The key finding was that PV-loop–based myocardial work parameters differ between amyloidosis subtypes (AL versus ATTR) and from controls, supporting their use as subtype differential diagnostic markers. Scientifically and clinically, myocardial work on CMR may improve noninvasive phenotyping of amyloid cardiomyopathy when ejection fraction is preserved.
Liang S, Chen J, Deng Q et al. · Insights into imaging · (2026) · View on PubMed ↗ · Free PDF ↗
CMR biomarkers in pulmonary arterial hypertension
The Prognostic Value of Entropy from T1 Mapping in Pulmonary Arterial Hypertension.
This prospective study evaluated prognostic biomarkers derived from cardiovascular magnetic resonance (CMR) T1 mapping—native T1, extracellular volume fraction (ECV), and entropy—in patients with pulmonary arterial hypertension (PAH) assessed within 72 hours of right heart catheterization (RHC). The key finding was that myocardial entropy from T1 mapping had prognostic value for all-cause mortality or lung transplantation, with outcomes analyzed using Cox proportional hazards and Kaplan–Meier methods. This is significant because it identifies a potentially useful CMR-derived metric for risk stratification in PAH beyond conventional imaging parameters.
Zhao J, Guo J, He J et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
CMR feature tracking & early hypertrophy-related dysfunction
Quantitative assessment of myocardial dysfunction in mild focal left ventricular hypertrophy using CMR feature tracking.
This retrospective study assessed myocardial dysfunction in patients with mild focal left ventricular hypertrophy (MF-LVH) by measuring left ventricular (LV) and left atrial (LA) deformation using CMR feature tracking (CMR-FT). The key finding was that CMR-FT–derived strain parameters can differentiate dysfunction patterns in MF-LVH compared with hypertrophic cardiomyopathy without late gadolinium enhancement (HCM-non-LGE) and healthy controls, supported by multivariable logistic regression and ROC analyses. Clinically, this suggests CMR-FT strain metrics may improve characterization of early or subtle hypertrophy-related dysfunction.
Wang X, Yao Y, Yang W et al. · Cardiology · (2026) · View on PubMed ↗
Microstructural assessment of hypertrophic cardiomyopathy with preserved left ventricular ejection fraction using second-order motion-compensated spin echo diffusion tensor cardiovascular magnetic resonance imaging.
This cross-sectional observational study used second-order motion-compensated spin echo diffusion tensor cardiovascular magnetic resonance imaging (M2-cDTI) at 1.5T to assess myocardial microstructure in 41 patients with hypertrophic cardiomyopathy (HCM) with preserved LVEF and 21 healthy volunteers. The key finding was that cDTI detects microstructural abnormalities beyond what is captured by late gadolinium enhancement (LGE), indicating additional diffuse or non-LGE-related tissue changes. Scientifically, it suggests cDTI may improve characterization of HCM pathology and potentially refine risk or disease phenotyping beyond conventional LGE imaging.
Xu J, Wang S, Du F et al. · European journal of radiology · (2026) · View on PubMed ↗
Myocardial tissue characterization: LGE phenotyping & prognosis
Association of Cardiac MRI-Derived Epicardial Adipose Tissue Index With Adverse Clinical Outcomes in Heart Failure With Preserved Ejection Fraction.
This retrospective study evaluated 265 patients with heart failure with preserved ejection fraction (HFpEF) to determine whether the cardiac MRI-derived epicardial adipose tissue index (EATI), quantified on cine images, predicts adverse outcomes. Higher EATI was associated with increased major adverse cardiovascular events (MACE), including cardiac death and HF-related readmission. These findings suggest that EATI on routine cardiac MRI may serve as an imaging biomarker for risk stratification in HFpEF.
Ma S, Qian L, Lou K et al. · Journal of magnetic resonance imaging : JMRI · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗
Development and Prospective Validation of an Interpretable Machine Learning Model Integrating Cardiac MRI Extracellular Volume for 1-Year MACE Prediction Post-STEMI.
This study developed and prospectively validated an interpretable machine learning model that integrates cardiac MRI extracellular volume (CMR-ECV) with clinical variables to predict 1-year major adverse cardiac events (MACE) after percutaneous coronary intervention for ST-segment elevation myocardial infarction (STEMI). The key finding was that adding ECV and using an interpretable feature-selection strategy (Boruta algorithm) improved 1-year MACE prediction performance in a prospective cohort. Scientifically and clinically, it provides a more transparent, ECV-informed risk tool for post-STEMI prognosis that may help identify patients who could benefit from intensified follow-up or therapy.
Zhao Z, Zhang Z, Yang Y et al. · Academic radiology · (2026) · View on PubMed ↗
A Visual LGE Extent Cutoff for Mortality Risk Stratification in Ischemic Cardiomyopathy.
This bicentric retrospective French study assessed late gadolinium enhancement (LGE) extent on cardiovascular magnetic resonance in 3,591 patients with ischemic cardiomyopathy and left ventricular ejection fraction (LVEF) <50%. The key finding was the derivation of an optimal semi-quantitative LGE segments cutoff to stratify mortality risk in this high-risk subgroup. This provides a practical imaging threshold that may improve prognostic risk stratification when fully quantitative LGE methods are not feasible.
Unger A, Garot J, Duhamel S et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
Identifying the High-Risk Arrhythmic Mitral Valve Prolapse Phenotype by Imaging.
This review article studied the imaging identification of the high-risk arrhythmic mitral valve prolapse (AMVP) phenotype, focusing on malignant mitral valve prolapse. The key finding was that malignant MVP can be recognized by a constellation of imaging features—myxomatous (often bileaflet) MVP with mitral annular disjunction, abnormal valvular–myocardial mechanics, and associated arrhythmogenic substrate markers such as complex ventricular ectopy and nonsustained ventricular tachycardia. Clinically, defining this imaging phenotype supports earlier recognition of patients at high risk for malignant ventricular arrhythmias and sudden cardiac death.
Thamman R, Haugaa KH, Hung J et al. · JACC. Cardiovascular imaging · (2026) · View on PubMed ↗
Cardiac imaging for thrombus, embolism, and intracardiac masses
Abdominal Pain as the First Presentation of Severe Heart Failure With Reduced Ejection Fraction and Left Ventricular Thrombus in a Young Asymptomatic Patient: A Diagnostic Interception.
This clinical case report described a young, asymptomatic physically active patient whose first presentation was abdominal pain, leading to incidental detection of severe heart failure with reduced ejection fraction (HFrEF) and a left ventricular apical thrombus. Early cardiac evaluation and management resulted in complete thrombus resolution. The case highlights the need to consider occult cardiac decompensation and ventricular thrombus in atypical presentations, enabling timely intervention to prevent embolic complications.
Alarfaj MO, Alsuwailem BS, Aljeezan MK et al. · Clinical case reports · (2026) · View on PubMed ↗ · Free PDF ↗
PFO-Mediated Paradoxical Coronary Embolism Causing Myocardial Infarction: Concordant Imaging Findings.
This JACC Case Reports report describes a 36-year-old man with myocardial infarction caused by paradoxical coronary embolism in the setting of a patent foramen ovale (PFO). The key finding was concordant multimodality imaging: coronary angiography showed a distal thrombotic occlusion without atherosclerosis, while cardiac MRI demonstrated subendocardial-to-transmural infarction with edema confined to the corresponding vascular territory, and echocardiography confirmed PFO with right-to-left shunting. Clinically, it illustrates how integrated imaging can establish causality in suspected paradoxical coronary embolism and guide appropriate management of the embolic source.
Shrestha A, Wong C, Theuerle J et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Multimodality Imaging of a Massive Intrapericardial Mediastinal Hemangioma: A Diagnostic Challenge.
This case report describes a 68-year-old man with a massive intrapericardial mediastinal hemangioma who had a severe iodinated contrast allergy, creating a diagnostic and procedural challenge. The key finding was that an iodine-free multimodality strategy—2′-deoxy-2′-[F-18] fluoro-D-glucose PET/CT plus cardiac MRI and contrast-enhanced ultrasound, guided by 3D reconstruction—enabled safe complete surgical resection of an adventitial mixed hemangioma. Scientifically and clinically, it demonstrates a practical imaging pathway when iodinated contrast is contraindicated, improving diagnostic confidence and surgical planning.
Weng J, Han J, Mao Y et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Guiding Pacemaker Implantation With Multimodality Imaging in an Adult With Ventricular Septal Defect.
This JACC Case Reports report describes a 57-year-old adult with repaired congenital ventricular septal defect and other congenital heart disease history who developed complete heart block requiring pacemaker implantation. The key finding was that multimodality imaging was used to plan the procedure by clarifying complex septal anatomy and informing optimal lead positioning strategies to improve procedural safety. Clinically, it supports routine use of advanced imaging for individualized pacemaker planning in adults with congenital heart disease and challenging conduction-system anatomy.
Singh AK, Eastwood C, Wong C · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Intracardiac Thrombi Mimicking Cardiac Metastases in a Patient With Lung Adenocarcinoma.
This case report studied a 50-year-old man with lung adenocarcinoma and venous thromboembolism who developed two right-sided intracardiac masses, using cardiac magnetic resonance (CMR) and histopathology after surgical excision. Despite therapeutic anticoagulation, CMR suggested cardiac metastases, but pathology confirmed organizing thrombus and the remaining ventricular lesion resolved after 1 month of therapeutic enoxaparin. Scientifically and clinically, it shows that cancer-associated intracardiac thrombi can mimic metastatic disease on CMR, so anticoagulation response and tissue diagnosis are critical to avoid misclassification.
Lembo M, De Vivo R, La Mura L et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Primary Cardiac Leiomyosarcoma in a Young Patient: A Therapeutic Challenge.
This case report studied a 29-year-old man with primary cardiac leiomyosarcoma, using echocardiography, cardiac magnetic resonance (CMR), positron emission tomography (PET), and histopathology with immunohistochemistry for diagnosis. The multimodality imaging identified a cardiac mass and pathology/immunohistochemistry confirmed leiomyosarcoma, and the patient remained alive at 20 months while receiving systemic therapy. The scientific and clinical significance is that early recognition using advanced imaging plus tissue diagnosis is essential for managing this rare, aggressive sarcoma despite the lack of standardized treatment.
Calzadilla-Gutierrez HR, Blanco-Adrian N, Vaca-Villarroel JM et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Papillary fibroelastoma of the coumadin ridge as an unusual cause of recurrent ischemic stroke: a case report.
This case report studied a 51-year-old woman with recurrent ischemic stroke in whom cardiac papillary fibroelastoma (PFE) of the coumadin ridge was identified as the embolic source. The key finding was that multimodal imaging—transesophageal echocardiography (TEE) and cardiac magnetic resonance imaging (CMR)—revealed a highly mobile pedunculated mass near the left atrial appendage ostium, explaining recurrent posterior fossa infarcts after negative thrombophilia/autoimmune workup and exclusion of patent foramen ovale. This is significant because it underscores that rare benign tumors like PFE can cause recurrent stroke and that TEE/CMR are crucial for diagnosis and management planning.
Suchodolski A, Ogrodzka A, Kemona-Kałwa R et al. · The international journal of cardiovascular imaging · (2026) · View on PubMed ↗
Inflammatory myocarditis/pericarditis & immune-mediated injury
Acute Myocarditis as an Immune-Mediated Complication of Mpox Infection.
This case report describes a 32-year-old man with well-controlled HIV who developed acute myocarditis as an immune-mediated complication of mpox infection. The key finding was that cardiac MRI met updated Lake Louise Criteria, showing lateral-wall edema on T2-weighted imaging and nonischemic late gadolinium enhancement with preserved ejection fraction after coronary and embolic causes were excluded. Clinically, it supports considering mpox-associated myocarditis in patients with chest pain after mpox and demonstrates CMR’s role in confirming immune-mediated myocardial injury.
Khoury F, Kim JHJ, Baghdasaryan E et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Apical-to-Mid-Ventricular Phenotypic Shift in Recurrent Takotsubo Syndrome After Minor Trauma.
This case report studied an 84-year-old woman with recurrent Takotsubo syndrome (TTS) after minor trauma, using serial troponins, echocardiography, coronary angiography, left ventriculography, and cardiac magnetic resonance (CMR). After a ground-level fall with blunt chest trauma, she developed a mid-ventricular TTS variant (mid-ventricular akinesia with hyperkinetic apex) with elevated troponin and lateral T-wave inversions, confirmed by ventriculography and CMR. The clinical significance is that trauma can trigger atypical TTS phenotypes with apical-to-mid-ventricular shift, supporting variant-aware diagnosis to prevent misattribution to acute coronary syndrome.
Khoury F, Chandi M, Johal M et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Relapsing-Remitting Perimyocarditis and Emerging Acute Myeloid Leukemia.
This case report studied a 66-year-old man with relapsing-remitting perimyocarditis following Coxsackievirus B exposure who was ultimately found to have emerging acute myeloid leukemia (AML), using repeat CMR and endomyocardial biopsy. Initial work-ups were unrevealing, but repeat CMR showed biventricular dysfunction, new late gadolinium enhancement, myocardial edema, and a circumferential pericardial effusion, and biopsy confirmed severe lymphocytic myocarditis. Clinically, it suggests that persistent or relapsing myocarditis/perimyocarditis can be an early manifestation of AML and warrants ongoing hematologic evaluation even when initial testing is negative.
Zipperer-Giblin MB, Bowman JI, Patel N et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac Manifestations of EGPA: An Overlap Phenotype of Inflammatory Myocardial Injury and Takotsubo-Like Syndrome.
This case report studied a 42-year-old woman with eosinophilic granulomatosis with polyangiitis (EGPA) presenting with acute left ventricular (LV) dysfunction, lymphocyte-predominant myocardial inflammation, and a Takotsubo-like syndrome with LV thrombus. The key finding was that the patient’s cardiac presentation represented an overlap phenotype of inflammatory myocardial injury and Takotsubo-like physiology, confirmed in the setting of antineutrophil cytoplasmic antibodies (ANCA)-negative EGPA. Clinically, it highlights that EGPA can mimic Takotsubo syndrome and can be complicated by LV thrombus, supporting careful cardiac imaging and management for thromboembolic risk.
Shalit B, Buonomo G, Shaw DG et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Acute Pancreatitis Presenting With ST-Segment Elevation and Marked Troponin Elevation: A Diagnostic Dilemma in a Resource-Limited Setting-A Case Report.
This case report studied a patient with acute pancreatitis who presented with ST-segment elevation and marked troponin elevation in a resource-limited setting. The key finding was that acute myocardial injury associated with pancreatitis can closely mimic Type 1 acute coronary syndrome, making differentiation difficult when coronary angiography, cardiac MRI, and serial high-sensitivity troponin testing are unavailable. Clinically, the report highlights the need for careful diagnostic reasoning to avoid misdiagnosis and inappropriate reperfusion pathways in pancreatitis patients with ACS-like ECG and troponin patterns.
Aweke SK, Assale NM, Mengistu AG et al. · Clinical case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Eosinophilic heart disease (Loeffler’s endomyocarditis) & IL-5 therapy
Loeffler’s Endomyocarditis: Clinical characteristics and outcomes from a tertiary care centre registry.
This retrospective single-center registry analyzed 18 patients diagnosed with Loeffler’s endomyocarditis (cardiac manifestation of hypereosinophilic syndrome) between 2017 and 2025 using clinical data, biomarkers, echocardiography, cardiac MRI, and endomyocardial biopsies (n=8). Unsupervised clustering identified two clinical patterns: an acute inflammatory form with elevated troponin T and C-reactive protein, fever, and subepicardial late gadolinium enhancement, and a more chronic restrictive pattern. The findings refine phenotypic recognition and may guide prognosis and management strategies for this rare eosinophilic cardiomyopathy.
Buske P, Krieghoff C, Lücke C et al. · International journal of cardiology · (2026) · View on PubMed ↗ · Free PDF ↗
Fulminant Eosinophilic Myocarditis in Steroid-Refractory Hypereosinophilic Syndrome: Navigating the Thrombotic Stage With Targeted Biologic Therapy.
This JACC Case Reports report describes a 57-year-old woman with steroid-refractory hypereosinophilic syndrome who developed fulminant eosinophilic myocarditis (Loeffler endomyocarditis) with thrombotic and embolic complications. The key finding was that cardiac MRI identified a large laminar intracardiac thrombus and subendocardial necrosis, and targeted biologic therapy with mepolizumab (anti–interleukin-5) was used to navigate the thrombotic stage after relapse on steroids and hydroxyurea. Clinically, it highlights the role of CMR for detecting eosinophilic thrombo-inflammatory injury and supports IL-5–targeted therapy as a potential strategy in refractory hypereosinophilic cardiac disease.
Althobaiti M, Aldlgan D, Alfehaid L et al. · JACC. Case reports · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗
Loeffler’s Endomyocarditis With Embolic Stroke Secondary to Chronic Eosinophilic Leukemia With Therapy-Related Molecular Features.
This case report describes a 77-year-old man with chronic eosinophilic leukemia with therapy-related molecular features who developed Loeffler’s endomyocarditis complicated by embolic stroke. The key finding was that cardiac MRI demonstrated diffuse endomyocardial involvement consistent with eosinophil-mediated injury and mural thrombus, explaining the embolic presentation in the setting of clonal hypereosinophilia after R-CHOP chemotherapy. Clinically, it underscores that therapy-related clonal eosinophilic disorders can cause high-risk Loeffler’s endomyocarditis and that CMR can be pivotal for diagnosis when thromboembolic events occur.
Ramesh S, Yousif N, Affas Z et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Congestive hepatopathy monitoring in congenital heart disease
Native Spleen T1 Mapping for the Assessment of Hepatic Congestion in Children With Congenital Heart Disease.
This study investigated native spleen T1 relaxation time (ST1) as a marker of hepatic congestion in 120 children with congenital heart disease (CHD), including those with Fontan circulation, using CMR alongside blood tests and cardiac catheterization. The key finding was that ST1 was associated with hemodynamic parameters and biomarkers of liver injury, supporting its utility as a noninvasive surrogate for congestive hepatopathy risk. Clinically, ST1 mapping could help monitor hepatic congestion in pediatric CHD patients where repeated invasive assessment is undesirable.
Tao K, Yamamura K, Sato M et al. · Circulation reports · (2026) · View on PubMed ↗ · Free PDF ↗
Right ventricular remodeling after congenital interventions
Right Ventricular Function Assessed by Speckle Tracking Echocardiography in Patients Undergoing Transcatheter Pulmonary Valve Replacement.
This prospective study assessed right ventricular (RV) function before and after transcatheter pulmonary valve replacement (TPVR) in 50 patients using speckle tracking echocardiography (STE) to measure RV systolic strain and right atrial (RA) strain. The key finding was that STE-derived RV free-wall and chamber-specific longitudinal strain parameters changed after TPVR (pre-op, post-operative day 1, and at 6-month follow-up), supporting STE as a feasible surrogate for RV functional assessment when CMR is impractical. Scientifically, it supports STE for longitudinal monitoring of RV remodeling after TPVR, potentially improving follow-up care in pediatric and congenital heart disease populations.
Kucuk M, de Alba CG, Zablah J et al. · Pediatric cardiology · (2026) · View on PubMed ↗
Hypertrophic cardiomyopathy: exercise, risk, and phenotyping
Clinical phenotype and outcomes of low-risk HCM patients who maintained stable exercise habits during follow-up.
This cohort study characterized clinical phenotype and follow-up outcomes in 253 low-risk hypertrophic cardiomyopathy (HCM) patients stratified by reliably documented stable exercise habits (sedentary, mild, or vigorous). Patients who maintained regular exercise over follow-up showed a more favorable clinical and arrhythmic profile compared with sedentary patients. The results suggest that sustained physical activity may identify a subgroup of low-risk HCM with better long-term outcomes, informing risk stratification and counseling.
Pelliccia A, Ferrera A, Daniello CD et al. · International journal of cardiology · (2026) · View on PubMed ↗
Left ventricular ejection fraction recovery under contemporary quadruple guideline-directed therapy and the need for ICD/CRT-D implantation in HFrEF: a retrospective single-center cohort study.
This retrospective single-center cohort study evaluated 65 patients with heart failure with reduced ejection fraction (HFrEF) in Germany to determine left ventricular ejection fraction (LVEF) recovery under contemporary “quadruple” guideline-directed medical therapy and the implications for implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy-defibrillator (CRT-D) implantation. The key finding was that LVEF reassessment after at least three months of therapy is central to deciding on ICD/CRT-D, and real-world outcomes under beta-blocker, angiotensin receptor-neprilysin inhibitor, mineralocorticoid receptor antagonist, and SGLT2 inhibitor were characterized in this contemporary treated population. Scientifically and clinically, the results inform how often patients recover sufficient LVEF to potentially defer device implantation in modern HFrEF care.
Ajmi I, Frings MP, Forkmann M et al. · Expert review of cardiovascular therapy · (2026) · View on PubMed ↗ · Free PDF ↗
Suicide risk after prison release (public health epidemiology)
Sociodemographic, Criminological and Clinical Determinants in Suicide After Release From Prison: A 23-Year National Cohort Study.
This 23-year national cohort study examined suicide after prison release in all people incarcerated in Norway from 2000–2022 (Norwegian Prison Release Study linked to national registries). The key finding was the characterization of suicide mortality patterns over time after release and identification of sociodemographic, criminological, and clinical determinants associated with elevated post-release suicide risk compared with the general population. Scientifically and clinically, the results support targeted prevention strategies timed to high-risk periods following release.
Bukten A, Mehlum L, Fazel S et al. · Acta psychiatrica Scandinavica · (2026) · View on PubMed ↗ · Free PDF ↗
Non-cardiac biomedical imaging/biomarkers (e.g., melanoma mitosis, albinism rings)
Real-time assessment of mitotic rate in malignant melanoma by ex vivo confocal microscopy.
This pilot study investigated whether ex vivo confocal laser scanning microscopy (EVCM) can reliably assess mitotic rate in malignant melanoma, a prognostic marker relevant to sentinel lymph node decisions. The abstract truncates before reporting the accuracy or validation results. If validated, EVCM could enable rapid intraoperative or near-intraoperative quantification of mitotic activity to support timely melanoma management.
Hartmann D, Wex K, Braun A et al. · Clinical and experimental dermatology · (2026) · View on PubMed ↗
Concentric macular rings: ultrawide-field biomarker in pediatric albinism.
This retrospective study evaluated pediatric albinism patients using ultrawide-field (UWF) imaging to assess concentric macular rings (CMR) as a noninvasive biomarker of foveal hypoplasia (FH), with OCT used when feasible. The key finding was that the prevalence and morphology/size of concentric macular rings on UWF imaging correlated with FH grade and related macular features, providing a practical alternative when OCT acquisition is limited by nystagmus and poor fixation. Clinically, CMR on UWF imaging may improve phenotyping and risk stratification for visual impairment in children with albinism when OCT is difficult.
Caminal-Caramés M, Català Mora J, Díaz-Cascajosa J et al. · Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · (2026) · View on PubMed ↗
Materials science for water remediation (Cr(VI))
3D magnetic nanocomposite modified with molybdenum disulfide: preparation and application in aqueous Cr(vi) remediation.
This materials study developed a 3D molybdenum disulfide magnetic biochar nanocomposite (3DMMB) using traditional Chinese medicine residues as biomass feedstock and iron-based sludge as an iron source, then tested it for aqueous hexavalent chromium [Cr(VI)] remediation. The work found that solution pH strongly influenced Cr(VI) removal and that the fabricated 3DMMB enabled effective adsorption-based remediation. The approach provides a low-cost, high-performance adsorbent strategy for treating Cr(VI)-contaminated water using waste-derived components.
Duan X, Zhang J, Wang Y et al. · Nanoscale advances · (2026) · View on PubMed ↗
Cardiac imaging workflow & patient experience (anxiety/breath-hold)
A Milestone in the Globalization of Cardiovascular Magnetic Resonance and a Legacy for Brazil and Latin America.
This article described the milestone of SCMR Rio 2026 and its role in the globalization of cardiovascular magnetic resonance (CMR) with a legacy for Brazil and Latin America. The key finding is that the meeting catalyzed regional scientific capacity through Latin American leadership, education, certification, and multidisciplinary collaboration rather than only geographic internationalization. Scientifically and clinically, this supports broader access to high-quality CMR training and practice, which can improve research and patient care capacity in the region.
Rochitte CE, Azevedo C, Fernandes JL · Arquivos brasileiros de cardiologia · (2026) · View on PubMed ↗
MRI-specific anxiety, patient experience, beta-blocker therapy, and image quality during cardiac magnetic resonance imaging.
This mixed-methods study evaluated how MRI-specific anxiety, state anxiety, and patient experience affect breath-hold performance and image quality during cardiac magnetic resonance imaging in 53 early post-infarction patients. The key finding was that emotional distress and MRI-specific anxiety were associated with breath-hold effort/duration and consequently with CMR image quality, with relationships potentially varying by factors such as prior MRI experience, sex, and beta-blocker therapy. Clinically, the findings support incorporating anxiety assessment and mitigation strategies to improve CMR acquisition quality and reliability.
Wahlström S, Rosendahl L, Lundvall LL et al. · Radiography (London, England : 1995) · (2026) · View on PubMed ↗ · Free PDF ↗
Coronary involvement imaging in Kawasaki disease (CT/MRI/echo)
Coronary artery imaging in Kawasaki disease: recent updates in imaging techniques and clinical indications.
This review studied current and emerging imaging approaches for coronary artery involvement in Kawasaki disease across acute and chronic stages, emphasizing indications for computed tomography (CT) and magnetic resonance imaging (MRI) alongside echocardiography. The key finding is that multimodality imaging is necessary throughout disease progression, with echocardiography remaining first-line for coronary lesions and ventricular function while advances in coronary CT angiography improve diagnostic accuracy for coronary artery abnormalities. This is significant because it guides clinicians on when and how to use different imaging modalities to detect and monitor coronary complications in Kawasaki disease.
Patharateeranart K, Goo HW, Kotoku A et al. · The international journal of cardiovascular imaging · (2026) · View on PubMed ↗
Generated automatically on October 16, 2026. Covers PubMed articles published October 09, 2026 – October 16, 2026. Summaries are AI-generated; always consult the original publication for clinical or research decisions.