What's New in Cardiac MRI? — October 19, 2026
AI-summarised digest of 63 PubMed articles on Cardiac MRI published in the last 7 days.
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What’s New in Cardiac MRI?
October 19, 2026 · 63 articles · 15 research themes · covering October 12, 2026 – October 19, 2026
Overview
Across this week’s set of studies, cardiac MRI (CMR) continues to expand from “diagnosis” into quantitative risk stratification and mechanistic phenotyping. Multiple cohorts and models used CMR-derived tissue metrics—such as LGE fibrosis patterns, extracellular volume (ECV), T1/T2 mapping trajectories, and novel texture/entropy measures—to predict major adverse cardiovascular events in diverse settings (STEMI, HFpEF, pulmonary arterial hypertension, chronic aortic regurgitation, and hypertensive cardiomyopathy). Complementing this, feature-tracking and deformation approaches (LV/LA strain in early hypertrophy; diffuse fibrosis tracking with rotating-frame spin-lock T1ρ/RAFF2) suggest that subtle myocardial impairment can be detected before conventional imaging thresholds are crossed.
A second dominant theme is the clinical value of multimodality imaging to find “hidden” cardiac sources of embolism or to clarify complex differential diagnoses. Case reports used TEE/CMR to localize papillary fibroelastoma and paradoxical embolic mechanisms, while other reports highlighted thrombus mimics (e.g., organizing thrombus vs metastasis) and the need for CMR-based characterization in inflammatory or hematologic disorders (eosinophilic myocarditis/endomyocarditis, mpox-associated myocarditis, and EGPA with Takotsubo-like injury plus LV thrombus). In parallel, several studies addressed how imaging protocols and acquisition choices affect comparability—most notably 4D flow CMR harmonization and measurement-method variability for aortic root sizing—underscoring that standardization is essential for translating imaging biomarkers into consistent clinical thresholds.
Finally, the digest reflects a methodological shift toward scalable, safer, and more efficient cardiovascular care: AI for artifact prediction and cross-modality ECG+CMR integration, diffusion-model reconstruction from sparse slices, and noninvasive transplant surveillance frameworks to reduce reliance on invasive biopsy. Together with trials exploring endocrine and metabolic interventions (testosterone, cortisol lowering, dapagliflozin in fibrosis-negative HFpEF), the overall picture is of CMR and computational tools increasingly guiding both prognosis and personalized management—while also improving workflow feasibility and patient comfort.
Cardiac MRI biomarkers of myocardial dysfunction and fibrosis
Life-Course Blood Pressure Trajectories and Focal Myocardial Fibrosis in Older Age in MyoFit46.
This study used the MyoFit46 prospective 1946 birth cohort (≈500 participants) to test whether life-course blood pressure (SBP/diastolic BP measured at ages 36, 43, 53, 63, 69, and 77 years) is associated with later-life focal left ventricular (LV) fibrosis measured by cardiac magnetic resonance (CMR) late gadolinium enhancement (LGE) using the 3-SD and 5-SD methods at age 77. The abstract truncation prevents reporting the specific direction/magnitude of the association between BP trajectory steepness/cumulative burden and LGE. If confirmed, these findings would clarify how long-term hypertension patterns translate into myocardial fibrosis risk and could improve lifetime risk stratification using CMR-derived fibrosis endpoints.
Topriceanu CC, Webber M, Shiwani H et al. · Hypertension (Dallas, Tex. : 1979) · (2026) · View on PubMed ↗
Left ventricular myocardial strain impairment correlates with cerebral small vessel disease burden in patients with normal ejection fraction.
This cross-sectional study evaluated whether subclinical left ventricular myocardial strain impairment is associated with cerebral small vessel disease (CSVD) burden in 139 participants with preserved left ventricular ejection fraction using concurrent cardiac and brain magnetic resonance imaging (MRI). It found that impaired left ventricular myocardial strain correlated with greater CSVD burden despite normal ejection fraction. This is clinically significant because it links subtle cardiac dysfunction to neurovascular microvascular injury markers, suggesting a potential imaging-based pathway for early risk identification.
Wang W, Zhang X, Liang M et al. · Brain research bulletin · (2026) · View on PubMed ↗ · Free PDF ↗
Clinical phenotype and outcomes of low-risk HCM patients who maintained stable exercise habits during follow-up.
This cohort study examined clinical phenotype and outcomes in 253 low-risk hypertrophic cardiomyopathy (HCM) patients stratified by reliably documented stable exercise habits during follow-up (sedentary, mild, and vigorous exercise). It found that maintaining regular exercise over time identified a subgroup with a more favorable clinical phenotype and distinct follow-up outcomes compared with sedentary behavior. This is significant because it informs risk stratification and lifestyle guidance for low-risk HCM patients engaged in long-term exercise programs.
Pelliccia A, Ferrera A, Daniello CD et al. · International journal of cardiology · (2026) · View on PubMed ↗
Septal thickness to QRS voltage ratio in Lead I/aVR: A simple tool for estimating cardiac amyloid burden.
This study assessed whether an integrated echocardiographic-electrocardiographic (echo-ECG) index—maximum septal thickness (MST) divided by QRS voltage in lead I and/or aVR—can estimate cardiac amyloid burden in patients with suspected cardiac amyloidosis. It found that the MST/QRS-voltage ratio correlated with cardiac magnetic resonance (CMR)–derived extracellular volume (ECV), the reference standard for noninvasive amyloid quantification. This is significant because it provides a simple, widely available tool for amyloid burden estimation when CMR ECV is limited by cost or availability.
Sclafani M, Arcari L, Tini G et al. · International journal of cardiology · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗
Recurrent Nonischemic Left Ventricular Aneurysms: A Cardiac MRI-Driven Diagnosis in a DES Variant Carrier.
This case report studied recurrent nonischemic left ventricular aneurysms in a 24-year-old man using cardiac magnetic resonance (CMR)-driven diagnosis in the context of a disease-associated variant carrier (DES variant). The key finding was that initial CMR identified an apical true aneurysm with normal coronary arteries and successful surgical treatment, while 5 years later CMR detected a new inferolateral basal aneurysm in a previously normal region after re-evaluation for recurrent ventricular tachycardia. Clinically, it supports serial CMR surveillance for recurrent aneurysm formation in nonischemic cardiomyopathy/variant carriers presenting with ventricular arrhythmias.
Garcia NP, Forti D, Tassine Penatti LA et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Left ventricular ejection fraction recovery under contemporary quadruple guideline-directed therapy and the need for ICD/CRT-D implantation in HFrEF: a retrospective single-center cohort study.
This study used CMR-defined left ventricular systolic impairment (LVEF <50%) in UK Biobank Imaging Enhancement Programme participants to test whether regional fat distribution predicts mortality beyond body mass index (BMI), addressing the “obesity paradox.” The key finding was that specific patterns of adiposity (regional fat phenotypes) were associated with mortality risk in people with LV systolic dysfunction, suggesting BMI alone can miss metabolically adverse fat distribution. This has prognostic implications for risk stratification and potentially for targeting interventions based on fat distribution rather than BMI.
Ajmi I, Frings MP, Forkmann M et al. · Expert review of cardiovascular therapy · (2026) · View on PubMed ↗ · Free PDF ↗
Divergent aortic root cusp-to-cusp measurement techniques on CMR: geometric implications and threshold reclassification.
This retrospective analysis compared divergent aortic root cusp-to-cusp measurement techniques on non-contrast 3D CMR in 50 patients (mean age ~42 years) and evaluated how technique choice reclassifies risk for prophylactic root replacement. The widest-to-widest cusp-to-cusp method produced systematically higher measurements than the middle cusp-to-cusp approach when compared with a traced aortic root perimeter. Scientifically and clinically, the work highlights that measurement methodology can shift surgical thresholds and therefore should be standardized or accounted for in guideline application.
Zelis JM, van Dijk A, Duijnhouwer TD et al. · European heart journal. Imaging methods and practice · (2026) · View on PubMed ↗ · Free PDF ↗
Quantitative assessment of myocardial dysfunction in mild focal left ventricular hypertrophy using CMR feature tracking.
This retrospective study evaluated left ventricular (LV) and left atrial (LA) myocardial deformation in 36 patients with mild focal left ventricular hypertrophy (MF-LVH), compared with 44 patients with hypertrophic cardiomyopathy without late gadolinium enhancement (HCM-non-LGE) and 32 healthy controls, using cardiac magnetic resonance feature tracking (CMR-FT). MF-LVH patients showed measurable impairment in LV and LA strain parameters on CMR-FT, with statistical discrimination supported by multivariable logistic regression and ROC analyses versus HCM-non-LGE and healthy controls. These findings suggest CMR-FT–derived strain metrics can quantitatively detect early myocardial dysfunction in MF-LVH, potentially improving risk stratification beyond conventional imaging.
Wang X, Yao Y, Yang W et al. · Cardiology · (2026) · View on PubMed ↗
CMR-based risk prediction and prognostic modeling
Association of Cardiac MRI-Derived Epicardial Adipose Tissue Index With Adverse Clinical Outcomes in Heart Failure With Preserved Ejection Fraction.
This retrospective study evaluated whether cardiac MRI–derived epicardial adipose tissue index (EATI) predicts major adverse cardiovascular events (MACE) in 265 patients with heart failure with preserved ejection fraction (HFpEF). Higher EATI measured on 1.5T balanced steady-state free precession cine images was associated with increased MACE risk (cardiac death and HF readmission). These findings support EATI as a potentially actionable cardiac MRI biomarker for risk stratification in HFpEF.
Ma S, Qian L, Lou K et al. · Journal of magnetic resonance imaging : JMRI · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗
Development and Prospective Validation of an Interpretable Machine Learning Model Integrating Cardiac MRI Extracellular Volume for 1-Year MACE Prediction Post-STEMI.
This prospective development and validation study created an interpretable machine learning model to predict 1-year MACE after STEMI treated with percutaneous coronary intervention, using clinical variables plus cardiac MRI extracellular volume (ECV). Incorporating CMR-ECV improved prediction of 1-year MACE compared with models using clinical features alone, with feature selection performed using Boruta algorithms. Clinically, this provides a transparent, ECV-informed risk tool to identify STEMI patients at higher near-term risk.
Zhao Z, Zhang Z, Yang Y et al. · Academic radiology · (2026) · View on PubMed ↗
Complex relationship between iron status and outcomes of STEMI: hypothesis-generating study.
This hypothesis-generating observational cohort study examined how iron status relates to outcomes across short-, mid-, and long-term follow-up in patients with ST-elevation myocardial infarction (STEMI) without prior heart failure (n=167). The key finding was that the prognostic impact of iron deficiency depended on how iron status was defined and when iron markers were sampled (e.g., at presentation), leading to variable associations with outcomes. Scientifically, it suggests that future risk prediction and intervention studies in STEMI should standardize iron marker timing and deficiency definitions to clarify whether iron deficiency is causally harmful or a marker of disease severity.
Vera-Aviles M, Kabir SN, Christodoulou MD et al. · Cardiovascular research · (2026) · View on PubMed ↗
The Prognostic Value of Entropy from T1 Mapping in Pulmonary Arterial Hypertension.
This prospective study evaluated whether myocardial entropy derived from T1 mapping on CMR predicts outcomes in pulmonary arterial hypertension (PAH) patients assessed within 72 hours of right heart catheterization (RHC). The key finding was that T1-mapping–based entropy (along with related measures such as native T1 and extracellular volume fraction) stratified risk for the composite endpoint of all-cause mortality or lung transplantation using Cox regression and Kaplan–Meier analyses. If confirmed, entropy could provide a noninvasive CMR biomarker to improve prognostication in PAH beyond conventional clinical and hemodynamic variables.
Zhao J, Guo J, He J et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
CMR techniques for myocardial tissue characterization (T1/T2/LGE/ECV/advanced mapping)
Rotating Frame Spin-Lock Cardiac MRI Method at 9.4 T Can Characterize Diffuse Fibrosis in Progressing Hypertensive Heart Disease in Mice.
In a mouse model of progressing hypertensive heart disease induced by angiotensin II infusion for 28 days, this study tested whether rotating frame spin-lock cardiac MRI at 9.4T using continuous-wave T1ρ and RAFF2 can characterize diffuse myocardial fibrosis. CW-T1ρ and RAFF2 showed complementary sensitivity to diffuse fibrosis progression compared with native T1 and late gadolinium enhancement (LGE). This supports rotating-frame spin-lock techniques as noninvasive tools for tracking diffuse fibrosis beyond conventional T1/LGE in hypertensive cardiomyopathy.
Kiviluoto R, Törmä D, Tawfek A et al. · Magnetic resonance in medicine · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac MRI in heart failure with preserved ejection fraction (HFpEF) and diastolic dysfunction
Dapagliflozin in phenotypically stratified HFpEF without myocardial fibrosis: the STADIA-HFpEF randomized crossover trial.
This randomized, double-blind, placebo-controlled crossover trial (34 weeks) tested whether dapagliflozin improves left ventricular (LV) distensibility in phenotypically stratified heart failure with preserved ejection fraction (HFpEF) patients without significant myocardial fibrosis. The abstract truncation prevents stating the trial’s primary efficacy result on LV distensibility. If dapagliflozin shows benefit in this fibrosis-negative HFpEF subgroup, it would support mechanism-targeted use of SGLT2 inhibitors for diastolic dysfunction driven by cardiomyocyte stiffness rather than extracellular matrix fibrosis.
Scheffer M, van Maarschalkerwaart W, Dong C et al. · European heart journal. Cardiovascular pharmacotherapy · (2026) · View on PubMed ↗ · Free PDF ↗
Cirrhotic cardiomyopathy: A comprehensive review of pathophysiology, diagnosis, and management.
This narrative review synthesized literature up to December 2025 on cirrhotic cardiomyopathy (CCM), focusing on pathophysiology, diagnostic criteria, imaging modalities, biomarkers, and management in patients with liver cirrhosis. The key finding is that CCM is common but underrecognized, with reported prevalence varying widely (29% to 67.2%) depending on diagnostic criteria, and that advanced imaging (including global longitudinal strain) is important for detection. Clinically, the review supports improved recognition and standardized diagnostic approaches to guide management—especially in the context of liver transplantation.
Zhang L, Yi J · Medicine · (2026) · View on PubMed ↗ · Free PDF ↗
Effects of testosterone on exercise capacity in postmenopausal women with stage B heart failure.
In a single-center, double-blind, randomized, placebo-controlled crossover trial, postmenopausal women aged ≥55 years with stage B heart failure and reduced exercise capacity were assigned transdermal testosterone 5 mg/day or placebo for 4 months. The study tested whether testosterone improves exercise capacity (including V˙O2peak) compared with placebo in this diastolic dysfunction/cardiac remodeling population. If effective, testosterone could represent a modifiable endocrine intervention to improve functional capacity in early-stage heart failure, but the clinical impact depends on the trial’s results.
Grant J, Alexander SE, Marwick TH et al. · Climacteric : the journal of the International Menopause Society · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiovascular effects of metyrapone treatment in patients with mild autonomous cortisol secretion: a secondary analysis.
This secondary analysis of a prospective, open-label, single-center study investigated cardiovascular effects of cortisol-lowering therapy in 15 patients with mild autonomous cortisol secretion (MACS) before and after 12 weeks of evening metyrapone dosing (500 mg at 6 PM and 250 mg at 10 PM). The intervention was assessed for changes in blood pressure regulation, cardiac fat depots, cardiac morphology/function, and other cardiovascular risk factors using pre/post clinical and imaging measures. The findings are clinically significant because they address whether pharmacologic cortisol suppression with metyrapone can reduce cardiovascular risk in MACS, a condition linked to increased mortality.
Niziolek H, Just I, Baumgartner C et al. · The Journal of clinical endocrinology and metabolism · (2026) · 2 citations · View on PubMed ↗ · Free PDF ↗
Coronary microvascular dysfunction (CMD) and ischemia without obstructive CAD
Coronary microvascular dysfunction in patients undergoing transcatheter aortic valve implantation: A systematic review and meta-analysis.
This systematic review and meta-analysis synthesized evidence on coronary microvascular dysfunction (CMD) in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI), focusing on pooled CMD prevalence, diagnostic modality effects, changes in coronary flow reserve (CFR) and microvascular resistance, and prognostic impact on major adverse cardiovascular events (MACE). The analysis concluded that CMD is relatively common after TAVI and that baseline CMD meaningfully influences subsequent MACE risk. These findings are clinically important because they suggest CMD assessment may refine risk stratification and potentially identify patients who could benefit from targeted microvascular therapies.
Panyawongkhanti M, Chintrakulchai P, Tanking C et al. · PloS one · (2026) · View on PubMed ↗ · Free PDF ↗
Left ventricular end-diastolic pressure in women with ischemia and no obstructive coronary artery disease: The women’s ischemia syndrome evaluation - Coronary microvascular dysfunction study (WISE-CVD).
This study evaluated women with ischemia and no obstructive coronary artery disease (INOCA) (n=253) to determine whether coronary microvascular dysfunction (CMD)–mediated impairment in LV relaxation contributes to elevated left ventricular end-diastolic pressure (LVEDP), using invasive coronary functional testing (CFT) and a pre-defined subset undergoing cardiac MRI (CMRI). It found that CMD-related physiology was associated with higher resting LVEDP, supporting a mechanistic link between microvascular dysfunction and impaired LV relaxation. This is clinically significant because it clarifies a pathophysiologic contributor to HFpEF-like hemodynamics in INOCA, potentially guiding targeted therapies.
Ranasinghe S, Tjoe B, Chang J et al. · International journal of cardiology · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗
Fully quantitative CMR rest perfusion reveals myocardial perfusion abnormality in Kawasaki disease: Association with left ventricular Remodeling.
This prospective single-center study investigated myocardial perfusion abnormalities in 87 children with Kawasaki disease using fully quantitative CMR rest perfusion with myocardial blood flow (MBF) corrected for heart rate–blood pressure product (MBFcor), and related these findings to left ventricular (LV) remodeling. It found that quantitative rest perfusion abnormalities were present in Kawasaki disease and were associated with LV remodeling measures. This is significant because it provides objective, spatially informative perfusion biomarkers that may help predict or monitor cardiac remodeling risk in pediatric KD.
Zhou Z, Ye P, Wang C et al. · International journal of cardiology · (2026) · View on PubMed ↗
Valvular heart disease imaging and outcomes (including aortic regurgitation/stenosis and MR)
Optimizing Echocardiographic Evaluation of Chronic Mitral Regurgitation: Comparison With Cardiac Magnetic Resonance Imaging and Implications for Guideline Recommendations.
This prospective study compared transthoracic echocardiography (TTE) using American Society of Echocardiography (ASE) native mitral regurgitation (MR) criteria against quantitative cardiac magnetic resonance (CMR) in 177 patients with chronic MR. The key finding was that the performance of ASE criteria—especially when fewer than four criteria are present—can be optimized by benchmarking against CMR severity grading. This work is important for refining guideline-based echocardiographic assessment of MR severity to improve diagnostic accuracy when CMR is not available.
El-Tallawi KC, Angulo C, Chamsi-Pasha M et al. · JACC. Cardiovascular imaging · (2026) · View on PubMed ↗
Impact of the Extent, Pattern, and Location of Replacement Myocardial Fibrosis on Clinical Outcomes in Aortic Regurgitation.
This study examined how the extent, pattern, and anatomical location of late gadolinium enhancement (LGE) replacement myocardial fibrosis on contrast-enhanced CMR relates to outcomes in patients with chronic aortic regurgitation (AR). LGE characteristics were associated with subsequent major adverse cardiovascular events (MACE), including cardiovascular mortality, heart transplantation, or HF rehospitalization. The findings suggest that more granular LGE phenotyping could improve prognostic assessment and clinical decision-making in AR.
Li B, Dai L, Liu Y et al. · European heart journal. Cardiovascular Imaging · (2026) · View on PubMed ↗
Coronary artery imaging in Kawasaki disease: recent updates in imaging techniques and clinical indications.
This narrative review summarized how coronary artery involvement in Kawasaki disease should be assessed across all disease stages, focusing on recent advances and clinical indications for imaging techniques. It emphasizes that echocardiography remains first-line throughout disease stages for coronary lesions and ventricular function, while computed tomography angiography (CTA) and magnetic resonance imaging (MRI/CMR) provide complementary roles for acute and chronic evaluation, including improved diagnostic accuracy with newer CT techniques. The review supports multimodality imaging strategies to better detect and characterize coronary artery abnormalities in Kawasaki disease over time.
Patharateeranart K, Goo HW, Kotoku A et al. · The international journal of cardiovascular imaging · (2026) · View on PubMed ↗
Congenital heart disease and repaired Tetralogy of Fallot (rTOF) imaging
Septal dysfunction and Abnormal Systolic Stretch Are Associated with Right Ventricular Dysfunction in Repaired Tetralogy of Fallot.
This retrospective study examined 126 pediatric patients after repaired Tetralogy of Fallot (rToF) with contemporaneous ECG, echocardiography, and cardiac magnetic resonance (CMR) from 2019–2025 to determine relationships between septal dysfunction, abnormal systolic stretch, and right ventricular (RV) dysfunction. The abstract truncation prevents reporting the specific statistical associations, but the title indicates that septal dysfunction and abnormal systolic stretch are associated with RV dysfunction. If validated, these echocardiographic/CMR-mechanical markers could help identify rToF patients at risk for RV dysfunction and electro-mechanical dyssynchrony earlier.
Fournier E, Joye R, Bitterman Y et al. · Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · (2026) · View on PubMed ↗
Prenatal Diagnosis of Distal Aortopulmonary Window by Fetal Cardiac MRI.
This case report used fetal cardiac magnetic resonance imaging (MRI) to diagnose a distal aortopulmonary window in a fetus referred after suboptimal great-vessel visualization on ultrasound. Fetal cardiac MRI demonstrated the characteristic “heart-shaped” configuration of the great vessels consistent with a distal aortopulmonary window. The report highlights fetal cardiac MRI as a complementary technique when echocardiography/ultrasound cannot adequately define complex outflow tract anatomy.
Verley M, Anquetil S, Ferreira LN et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Guiding Pacemaker Implantation With Multimodality Imaging in an Adult With Ventricular Septal Defect.
This case report studied multimodality imaging to guide pacemaker implantation in a 57-year-old man with adult congenital heart disease (repaired ventricular septal defect) who developed complete heart block. The key finding was that multimodality imaging helped identify optimal lead positioning strategies to improve procedural safety and reduce technical difficulty in complex septal anatomy. Clinically, this supports using multimodality imaging for safer device implantation planning in adults with congenital heart disease and atrioventricular conduction disease.
Singh AK, Eastwood C, Wong C · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Pulmonary valve replacement and right-heart mechanics
Cardiovascular Magnetic Resonance Predictors of Residual Pulmonary Regurgitation and Biventricular Recovery After Pulsta Valve Implantation.
This retrospective study evaluated 98 patients undergoing self-expanding percutaneous pulmonary valve implantation (PPVI) with the Pulsta valve, using paired pre- and post-procedural cardiovascular magnetic resonance (CMR) to identify predictors of residual pulmonary regurgitation (PR), residual right ventricular enlargement (RVE), and residual biventricular imbalance (BVI). Residual PR and residual right-sided remodeling after PPVI were predicted by CMR-derived right ventricular outflow tract anatomy and pre-/post-procedural CMR measures of RV size and imbalance (with residual PR defined by post-procedure CMR criteria). These findings support using CMR beyond standard RV volume thresholds to better anticipate incomplete correction and guide follow-up/selection for PPVI in heterogeneous repaired tetralogy of Fallot–type anatomy.
Baek SM, Ahn C, Lee SY et al. · Pediatric cardiology · (2026) · View on PubMed ↗
Right Ventricular Function Assessed by Speckle Tracking Echocardiography in Patients Undergoing Transcatheter Pulmonary Valve Replacement.
This study evaluated right ventricular (RV) systolic function changes in 50 patients undergoing transcatheter pulmonary valve replacement (TPVR) using speckle tracking echocardiography (STE) at pre-op, post-operative day 1, and 6-month follow-up. RV free-wall longitudinal strain and RV four-chamber strain (along with right atrial reservoir and contraction strain) were used to quantify peri-procedural and mid-term changes in RV mechanics. These findings support STE as a practical alternative to cardiac magnetic resonance (CMR) for monitoring RV function after TPVR in pediatric/congenital cardiology settings.
Kucuk M, de Alba CG, Zablah J et al. · Pediatric cardiology · (2026) · View on PubMed ↗
4D flow CMR acquisition, standardization, and hemodynamic biomarkers
4D Flow Acquisition Parameters as Technical Correlates of Hemodynamic Measurements: An Analysis of the multicenter Tetralogy of Fallot Registry of 4D flow Energetics and Kinetics (TREK).
This multicenter observational analysis assessed how 4D flow cardiovascular magnetic resonance (CMR) acquisition parameters (including vendor, sequence, and signal quality) influence hemodynamic biomarkers in repaired tetralogy of Fallot (rTOF) across the TREK registry. Technical variability in 4D flow acquisition correlated with differences in aortic and right-ventricular measurements of kinetic energy, vorticity, and viscous energy loss. The results highlight the need for harmonization/standardization of 4D flow protocols before comparing biomarkers across sites or studies.
Loke YH, Lee M, O’Hara R et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
Establishing the reliability of non-contrast 4D flow in congenital heart disease at 1.5T.
This prospective cohort study assessed whether non-contrast 4D flow cardiac MRI at 1.5T correlates with standard 2D phase-contrast (2D PC) flow and ventricular stroke volumes in pediatric and young adult patients with suspected or confirmed congenital heart disease (CHD). Non-contrast 4D flow measurements were compared to 2D PC using Pearson correlations, linear mixed-effect correlations, and Bland–Altman analyses. If validated, non-contrast 4D flow could reduce reliance on contrast agents while preserving quantitative flow accuracy for CHD evaluation.
Brown NK, Romberg EK, Schmitt C et al. · Pediatric radiology · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiac imaging for thromboembolism and intracardiac masses
Abdominal Pain as the First Presentation of Severe Heart Failure With Reduced Ejection Fraction and Left Ventricular Thrombus in a Young Asymptomatic Patient: A Diagnostic Interception.
This clinical case report studied a young, asymptomatic, physically active patient who presented with abdominal pain and was incidentally found to have severe heart failure with reduced ejection fraction (HFrEF) and a left ventricular apical thrombus. It found that early cardiac evaluation (including BNP elevation, cardiomegaly, and ECG changes) enabled timely management leading to complete thrombus resolution. This is significant because it demonstrates how atypical abdominal pain can be the first presentation of severe HFrEF with LV thrombus and underscores the value of prompt cardiac assessment.
Alarfaj MO, Alsuwailem BS, Aljeezan MK et al. · Clinical case reports · (2026) · View on PubMed ↗ · Free PDF ↗
PFO-Mediated Paradoxical Coronary Embolism Causing Myocardial Infarction: Concordant Imaging Findings.
This case report describes a 36-year-old man with myocardial infarction due to paradoxical coronary embolism in the setting of a patent foramen ovale (PFO). Coronary angiography showed distal thrombotic occlusion without significant atherosclerosis, while cardiac MRI demonstrated infarction confined to the corresponding vascular territory. The concordant imaging supports PFO-mediated embolism as a causal mechanism and underscores the value of multimodality imaging when coronary embolism is suspected.
Shrestha A, Wong C, Theuerle J et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Multimodality Imaging of a Massive Intrapericardial Mediastinal Hemangioma: A Diagnostic Challenge.
This case report describes a 68-year-old man with a massive intrapericardial mediastinal hemangioma who had a severe iodinated contrast allergy. An iodine-free multimodality strategy using 2’-deoxy-2’-[F-18] fluoro-D-glucose PET/CT, cardiac MRI, and contrast-enhanced ultrasound—guided by 3D reconstruction—enabled safe complete surgical resection. The case demonstrates a practical diagnostic pathway when iodinated contrast is contraindicated.
Weng J, Han J, Mao Y et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Compound MYH7 Mutations: Risk Stratification Challenges in an Affected Family.
This case report studied sudden cardiac death risk stratification challenges in a familial hypertrophic cardiomyopathy (HCM) setting involving compound MYH7 mutations. The key finding was that the proband carried only one of two pathogenic MYH7 variants identified in his daughter (Ala655Thr and Gly571Arg), yet the daughter had obstructive HCM with cardiac arrest and an implantable cardioverter-defibrillator while the father had mild septal hypertrophy and nonsustained ventricular tachycardia. Clinically, it underscores that genotype-phenotype interpretation is difficult in MYH7 variant carriers and that risk stratification cannot rely solely on the presence of a single pathogenic variant.
Hammad A, Yeung A, Goldschmidt H et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Primary Cardiac Leiomyosarcoma in a Young Patient: A Therapeutic Challenge.
This case report studied diagnosis and treatment challenges of primary cardiac leiomyosarcoma in a 29-year-old man. The key finding was that echocardiography followed by cardiac magnetic resonance and positron emission tomography, along with histopathology and immunohistochemistry, confirmed primary cardiac leiomyosarcoma, and the patient remained alive at 20 months on systemic therapy. The clinical significance is that multimodal imaging plus tissue diagnosis are essential for this rare aggressive tumor, and standardized treatment remains unresolved.
Calzadilla-Gutierrez HR, Blanco-Adrian N, Vaca-Villarroel JM et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Papillary fibroelastoma of the coumadin ridge as an unusual cause of recurrent ischemic stroke: a case report.
This case report described a 51-year-old woman with palpitations and recurrent ischemic stroke (including left medulla oblongata and multiple posterior fossa infarcts) in whom extensive thrombophilic and autoimmune workup was negative and patent foramen ovale was excluded. Multimodal cardiac imaging with transesophageal echocardiography (TEE) and cardiac magnetic resonance imaging (CMR) identified a highly mobile pedunculated papillary fibroelastoma (PFE) attached to the coumadin ridge near the left atrial appendage ostium, providing an embolic source for stroke recurrence. The report highlights the clinical importance of considering PFE and using TEE/CMR to localize occult cardiac emboli when standard stroke etiologies are not found.
Suchodolski A, Ogrodzka A, Kemona-Kałwa R et al. · The international journal of cardiovascular imaging · (2026) · View on PubMed ↗
Inflammatory and immune-mediated myocarditis/endomyocarditis (including eosinophilic and viral)
Prospective Cardiac MRI study comparing Recovered COVID-19 patients with Recovered Non-COVID-19 Viral Respiratory Infection Patients (R-COVID-CMR).
This prospective longitudinal CMR study compared recovered COVID-19 patients with recovered non-COVID viral respiratory infection patients to determine differences in myocardial inflammation and involvement after infection. The abstract truncation prevents stating the magnitude or direction of the CMR inflammation differences between groups. If COVID-19 shows distinct or greater CMR-detected myocardial involvement than other viral infections, it would refine post-infection cardiac risk assessment and follow-up strategies.
Ho LK, Hei ST, Yan HS et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
Loeffler’s Endomyocarditis: Clinical characteristics and outcomes from a tertiary care centre registry.
This retrospective single-center registry studied 18 patients diagnosed with Loeffler’s endomyocarditis (cardiac manifestation of hypereosinophilic syndrome) between 2017 and 2025 using clinical data, biomarkers, echocardiography, cardiac MRI (CMR), and endomyocardial biopsies (n=8). It found two distinct patterns via hierarchical clustering: an acute inflammatory form with elevated troponin T, C-reactive protein, fever, and subepicardial late gadolinium enhancement, and a more chronic/restrictive pattern. This is significant because it characterizes disease phenotypes and may improve prognostication and management strategies for this rare eosinophilic cardiomyopathy.
Buske P, Krieghoff C, Lücke C et al. · International journal of cardiology · (2026) · View on PubMed ↗ · Free PDF ↗
Fulminant Eosinophilic Myocarditis in Steroid-Refractory Hypereosinophilic Syndrome: Navigating the Thrombotic Stage With Targeted Biologic Therapy.
This JACC Case Reports report describes a 57-year-old woman with steroid-refractory hypereosinophilic syndrome who developed fulminant eosinophilic myocarditis with thrombotic complications. Cardiac MRI identified a large laminar thrombus and subendocardial necrosis, and after relapse on steroids and hydroxyurea she was treated with mepolizumab (anti–interleukin-5). The case illustrates the potential role of targeted IL-5 blockade to manage the thrombotic/eosinophilic phase of Loeffler endomyocarditis when conventional therapy fails.
Althobaiti M, Aldlgan D, Alfehaid L et al. · JACC. Case reports · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗
Loeffler’s Endomyocarditis With Embolic Stroke Secondary to Chronic Eosinophilic Leukemia With Therapy-Related Molecular Features.
This case report describes a 77-year-old man with chronic eosinophilic leukemia and therapy-related molecular features who developed Loeffler’s endomyocarditis with embolic stroke. Cardiac MRI demonstrated diffuse endomyocardial involvement with mural thrombus, following echocardiographic detection of a large apical left ventricular thrombus. The report emphasizes that clonal eosinophilic disorders can drive high-risk end-organ damage and should prompt early cardiac imaging and aggressive management.
Ramesh S, Yousif N, Affas Z et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Acute Myocarditis as an Immune-Mediated Complication of Mpox Infection.
This case report describes a 32-year-old man with well-controlled HIV who developed acute immune-mediated myocarditis after mpox infection. With coronary and embolic causes excluded, cardiac MRI showed lateral-wall edema on T2-weighted imaging and nonischemic late gadolinium enhancement meeting the updated Lake Louise Criteria, and he recovered with supportive care. The report expands the clinical spectrum of mpox complications and supports CMR-based diagnosis of myocarditis in this setting.
Khoury F, Kim JHJ, Baghdasaryan E et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Apical-to-Mid-Ventricular Phenotypic Shift in Recurrent Takotsubo Syndrome After Minor Trauma.
This case report studied recurrent Takotsubo syndrome (TTS) after minor trauma in an 84-year-old woman with prior apical ballooning. The key finding was a phenotypic shift from classic apical TTS to a mid-ventricular variant after ground-level fall with blunt chest trauma, confirmed by echocardiography, coronary angiography excluding obstructive disease, left ventriculography, and cardiac magnetic resonance. The clinical significance is that trauma can trigger atypical TTS phenotypes, so clinicians should consider TTS variants when evaluating post-traumatic troponin elevation and regional wall-motion abnormalities.
Khoury F, Chandi M, Johal M et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Relapsing-Remitting Perimyocarditis and Emerging Acute Myeloid Leukemia.
This case report studied relapsing-remitting perimyocarditis as an initial presentation of emerging acute myeloid leukemia (AML) in a 66-year-old man. The key finding was that repeat cardiac magnetic resonance showed evolving biventricular dysfunction with myocardial edema and late gadolinium enhancement plus a circumferential pericardial effusion, and endomyocardial biopsy confirmed severe lymphocytic myocarditis while AML emerged over time. Scientifically and clinically, it emphasizes that recurrent or steroid-refractory perimyocarditis should prompt consideration of underlying hematologic malignancy and repeat diagnostic reassessment.
Zipperer-Giblin MB, Bowman JI, Patel N et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
BHSMS: a new software for searching the most stable structure of clusters based on the improved basin hopping algorithm.
This case report described a 42-year-old woman with EGPA who developed acute LV dysfunction consistent with Takotsubo-like syndrome alongside lymphocyte-predominant myocardial inflammation. The key finding was that the episode was complicated by LV thrombus. The significance is that EGPA can produce Takotsubo-like cardiac presentations that require careful imaging and management for both inflammation and thrombosis.
Zhang YY, Cheng Y, Zhang SW et al. · Physical chemistry chemical physics : PCCP · (2026) · View on PubMed ↗
Cardiac Manifestations of EGPA: An Overlap Phenotype of Inflammatory Myocardial Injury and Takotsubo-Like Syndrome.
This case report characterized cardiac manifestations of EGPA in a 42-year-old woman, focusing on an unusual presentation combining inflammatory myocardial injury and Takotsubo-like syndrome. The key finding was transient LV dysfunction with lymphocyte-predominant myocardial inflammation and LV thrombus. This is clinically important because it expands the differential diagnosis of Takotsubo-like syndromes and highlights thrombus risk in inflammatory EGPA myocarditis.
Shalit B, Buonomo G, Shaw DG et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Cardiotoxicity and cancer-related cardiac complications
FOLFOX-Associated Ventricular Fibrillation Arrest in a Patient With Colon Cancer.
This JACC Case Reports report describes a 43-year-old man with stage IIIB colon cancer who developed chest discomfort and out-of-hospital ventricular fibrillation arrest about 72 hours after his first FOLFOX cycle (leucovorin, 5-fluorouracil [5-FU], and oxaliplatin). Cardiac evaluation showed severe left ventricular dysfunction on echocardiography with subsequent improvement on cardiac magnetic resonance imaging and no myocardial edema or late gadolinium enhancement, supporting fluoropyrimidine-associated cardiotoxicity/arrhythmia. The case is clinically important because it underscores the life-threatening potential of fluoropyrimidines and the value of CMR in characterizing cardiotoxic injury patterns after chemotherapy.
Al Osta S, Ahmed M, Xu WD et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Transplantation surveillance and allograft vasculopathy
Sustained improvement in sickle cell cardiomyopathy after haematopoietic stem cell transplantation is superior to that with disease-modifying therapy.
This prospective clinical trial followed children and young adults with sickle cell disease (including HbSS and other genotypes) undergoing matched-sibling or haploidentical allogeneic hematopoietic stem cell transplantation (HSCT), using serial cardiac magnetic resonance (CMR) and echocardiography up to 36 months to compare myocardial remodeling after HSCT versus disease-modifying therapy. The key finding reported in the abstract is that sustained improvement in sickle cell cardiomyopathy after HSCT is superior to that achieved with disease-modifying therapy. Clinically, this supports HSCT as a more effective long-term strategy for reversing or improving cardiac remodeling in pediatric/young adult SCD beyond standard disease-modifying approaches.
Rai P, Selukar S, Bi Y et al. · British journal of haematology · (2026) · View on PubMed ↗
Multi-center study of CMR versus cardiac catheterization with endomyocardial biopsy for pediatric transplant surveillance: study protocol.
This study protocol describes a multi-center pediatric transplant surveillance approach to replace or reduce reliance on invasive endomyocardial biopsy (EMB) for detecting acute allograft rejection (AR) in pediatric heart transplant recipients (PHTX). It will validate non-invasive CMR using T1 and T2 parametric mapping together with blood biomarkers (including cell-free DNA [cfDNA] and microRNA [miRNA]) against EMB-based AR detection. If successful, it would provide a less invasive, pediatric-validated surveillance framework to improve safety and comfort while maintaining diagnostic accuracy for AR.
Heimerl AT, Crum K, Lockard CA et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗
Rapid Progression of Cardiac Allograft Vasculopathy With Sudden Cardiac Death Within the First Year of Heart Transplantation: A Case Report.
This case report describes a 56-year-old man with non-ischemic cardiomyopathy who underwent left ventricular assist device implantation followed by orthotopic heart transplantation (HT), with subsequent development of rapid cardiac allograft vasculopathy (CAV) and sudden cardiac death within the first year. The key clinical finding is that CAV progressed quickly and presented with atypical chest discomfort before sudden death, illustrating that sudden cardiac death can be the first manifestation of early CAV after HT. Scientifically and clinically, it highlights the need for vigilant early CAV monitoring and consideration of atypical symptoms in the first post-transplant year.
Dix M, Iskandar JP, He L et al. · Transplantation proceedings · (2026) · View on PubMed ↗
Diffuse elevations of T1 and T2 are common in newly transplanted pediatric cardiac grafts without rejection and decrease over time.
This prospective CMR study followed 14 pediatric heart transplant recipients without acute rejection who underwent 22 non-contrast 1.5T CMR scans, comparing newly transplanted grafts (≤6 months) with established grafts (≥12 months) and matched controls. Diffuse elevations of T1 and T2 parametric maps were common in new grafts despite no rejection and decreased over time. These results support using CMR T1/T2 trajectories to distinguish normal post-transplant myocardial remodeling from rejection-related injury in pediatric graft surveillance.
Vegulla RV, Blackwell S, Ceneri NM et al. · Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · (2026) · View on PubMed ↗ · Free PDF ↗
Arrhythmia phenotyping and electrophysiology case-based insights
The Innocent Delta Wave in Progressive Cardiomyopathy - Culprit vs Bystander.
This case report studied a 34-year-old man with progressive cardiomyopathy, recurrent palpitations, atrial fibrillation, and an acute ischemic stroke, in the context of familial hypertrophic cardiomyopathy (HCM) and conduction disease. It found that electrocardiographic features after cardioversion (including a short PR interval) and the HCM phenotype suggested an “innocent delta wave” as a bystander rather than the primary driver of the clinical events. The report is significant because it highlights the diagnostic pitfall of misattributing delta-wave findings in progressive cardiomyopathy and emphasizes careful clinical correlation.
Ansari AG, Shanmugam S, Vijay J et al. · The American journal of cardiology · (2026) · View on PubMed ↗
LGL-Phenocopy With Dual AV Nodal Physiology and Malignant SVT: A Diagnostic Pitfall With Sudden Deaths.
This case report studied Lown-Ganong-Levine (LGL) phenocopy with dual atrioventricular (AV) nodal physiology in a 45-year-old man presenting with malignant supraventricular tachycardia (SVT) and family history of sudden cardiac death. The key finding was that despite a short PR interval without preexcitation on postconversion ECG, the patient had dual AV nodal physiology and malignant SVT substrates associated with Hisian extrasystoles and QRS variability. Scientifically and clinically, it highlights that “benign” LGL-phenocopy ECG patterns can mask high-risk arrhythmogenic mechanisms requiring careful electrophysiologic evaluation.
Negm AY, Zhfan S, Khalil M et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Intracardiac Thrombi Mimicking Cardiac Metastases in a Patient With Lung Adenocarcinoma.
This case report studied cardiac magnetic resonance (CMR) findings of two right-sided intracardiac masses in a 50-year-old man with lung adenocarcinoma and venous thromboembolism who was receiving therapeutic anticoagulation. The key finding was that histopathology of an excised atrial mass showed organizing thrombus (not metastasis), and the remaining ventricular lesion resolved after 1 month of therapeutic enoxaparin. The clinical significance is that cancer-associated intracardiac thrombi can mimic metastatic disease on CMR, so anticoagulation response and tissue diagnosis may be critical before concluding cardiac metastases.
Lembo M, De Vivo R, La Mura L et al. · JACC. Case reports · (2026) · View on PubMed ↗ · Free PDF ↗
Imaging/AI methods, reconstruction, and workflow optimization
HeartFusion: A Cross-Modality Transformer for Accurate Cardiovascular Disease Diagnosis and Severity Assessment.
This retrospective cohort study trained and evaluated machine learning models to predict the occurrence of cardiac magnetic resonance (CMR) motion artifacts in 514 adult patients undergoing non-sedated CMR, using 15 baseline clinical features including psychological and physiological indicators. The best-performing model was eXtreme Gradient Boosting with AUC = 0.875, and the study also aimed to provide clinically interpretable post-hoc feature attribution. This is significant because accurate pre-scan artifact risk prediction could reduce rescans and improve workflow and patient experience in CMR.
Ji Y, Hu Y · Journal of visualized experiments : JoVE · (2026) · View on PubMed ↗
Machine Learning and Post-Hoc Feature Attribution for Predicting Cardiac MRI Motion Artifacts: A Retrospective Cohort Study.
This JoVE study developed the HeartFusion cross-modality Transformer to integrate electrocardiogram (ECG) and cardiac magnetic resonance (MRI) for cardiovascular disease diagnosis and severity assessment. The method encodes wavelet-derived ECG time-frequency representations and MRI structure (via TransUNet), aligns modality embeddings in a shared latent space using cross-modal attention, and performs classification with an ordinal regression head. Scientifically, it provides a framework for combining electrophysiology and anatomy to improve diagnostic accuracy and severity staging across CVD phenotypes.
Li Y, Cai Q, Li L et al. · Journal of visualized experiments : JoVE · (2026) · View on PubMed ↗
Real-time assessment of mitotic rate in malignant melanoma by ex vivo confocal microscopy.
This pilot study evaluated whether ex vivo confocal laser scanning microscopy (EVCM) can reliably measure mitotic rate in fresh malignant melanoma tissue. The central finding was that EVCM can assess mitotic activity, potentially extending its intraoperative diagnostic utility beyond morphology and Breslow thickness estimation. If validated, EVCM-based mitotic quantification could improve prognostication and guide sentinel lymph node decisions during melanoma surgery.
Hartmann D, Wex K, Braun A et al. · Clinical and experimental dermatology · (2026) · View on PubMed ↗
Latent Interpolation Learning Using Diffusion Models for Cardiac Volume Reconstruction.
This study proposed a Cardiac Latent Interpolation Diffusion (CaLID) framework to reconstruct 3D cardiac volumes from sparsely acquired 2D short-axis CMR slices without relying on predefined interpolation schemes or additional semantic inputs like segmentation labels or motion data. The key contribution is a diffusion-model-based latent interpolation approach that improves volumetric reconstruction quality under sparse sampling. This is significant for expanding the clinical utility of CMR by enabling more accurate 3D assessment from faster or more limited acquisition protocols.
Bubeck N, Shit S, Chen C et al. · IEEE transactions on medical imaging · (2026) · 1 citations · View on PubMed ↗ · Free PDF ↗
AI and Deep Learning in Cardiovascular Imaging: From Risk Stratification to Precision Phenotyping.
This review studied how artificial intelligence (AI) and deep learning can be applied to cardiovascular imaging for risk stratification and precision phenotyping across modalities such as chest radiography and computed tomography. It found that modern deep-learning architectures and training strategies can extract quantitative prognostic and phenotypic features from routine images that exceed conventional interpretation capacity. These advances are significant because they support more scalable, data-driven cardiovascular risk assessment and phenotyping in clinical practice.
Diao K, Lu J, Dimitrakakis A et al. · Arteriosclerosis, thrombosis, and vascular biology · (2026) · View on PubMed ↗
3D magnetic nanocomposite modified with molybdenum disulfide: preparation and application in aqueous Cr(vi) remediation.
This materials study developed a 3D molybdenum disulfide magnetic biochar nanocomposite (3DMMB) using traditional Chinese medicine residues as biomass feedstock and iron-based sludge as an iron source, then tested it for aqueous Cr(VI) remediation. It found that solution pH strongly influenced Cr(VI) removal and that the fabricated 3DMMB enabled efficient adsorption-based remediation. This is significant for environmental remediation because it offers a low-cost, high-performance adsorbent strategy using industrial/biomass waste inputs.
Duan X, Zhang J, Wang Y et al. · Nanoscale advances · (2026) · View on PubMed ↗ · Free PDF ↗
Concentric macular rings: ultrawide-field biomarker in pediatric albinism.
This retrospective study evaluated the prevalence and clinical relevance of concentric macular rings (CMR sign) on ultrawide-field (UWF) imaging as a noninvasive biomarker of foveal hypoplasia in pediatric albinism. The key finding was that UWF imaging (including green-filter UWF) could be used to assess CMR sign morphology/size in children where optical coherence tomography (OCT) is limited by nystagmus and poor fixation, and the CMR sign was analyzed in relation to foveal hypoplasia grading and visual acuity. Clinically, it supports UWF imaging as a practical biomarker approach for quantifying foveal hypoplasia in pediatric albinism when OCT acquisition is challenging.
Caminal-Caramés M, Català Mora J, Díaz-Cascajosa J et al. · Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · (2026) · View on PubMed ↗
Pattern and texton-based feature descriptors for diabetic foot ulcer detection.
This paper proposed a deep learning framework (DLS-DFUD) for diabetic foot ulcer (DFU) detection using a pipeline of preprocessing, segmentation, feature extraction, and classification. The key methodological contribution was using wavelet transform-based Wiener filtering (WT-WF) for noise reduction and improved image quality before segmentation and classification. Clinically, more accurate DFU detection could enable earlier intervention and reduce infection and amputation risk in diabetes care.
Mastanvali, Rajini NH, Laxmaiah M · Expert review of medical devices · (2026) · View on PubMed ↗
A Milestone in the Globalization of Cardiovascular Magnetic Resonance and a Legacy for Brazil and Latin America.
This article described the SCMR Rio 2026 meeting as a milestone in the globalization of cardiovascular magnetic resonance (CMR), emphasizing development of regional scientific capacity in Brazil and Latin America. The key finding is the documented transition from international participation to sustained local leadership, education, certification, and multidisciplinary collaboration. The significance is that such regional initiatives can expand access to high-quality CMR training and practice.
Rochitte CE, Azevedo C, Fernandes JL · Arquivos brasileiros de cardiologia · (2026) · View on PubMed ↗ · Free PDF ↗
Generated automatically on October 19, 2026. Covers PubMed articles published October 12, 2026 – October 19, 2026. Summaries are AI-generated; always consult the original publication for clinical or research decisions.